Article ; Online: Polydopamine Biomaterials for Skin Regeneration.
ACS biomaterials science & engineering
2022 Volume 8, Issue 6, Page(s) 2196–2219
Abstract: Designing biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic ... ...
Abstract | Designing biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of biomedical applications. Moreover, biomaterials based on PDA and its derivatives have near-infrared (NIR) absorption, excellent biocompatibility, intrinsic antioxidative activity, antibacterial activity, and cell affinity. PDA can regulate cell behavior by controlling signal transduction pathways. It governs the focal adhesion behavior of cells at the biomaterials interface. These features make melanin-like PDA a fascinating biomaterial for wound healing and skin regeneration. This paper overviews PDA-based biomaterials' synthesis, properties, and interactions with biological entities. Furthermore, the utilization of PDA nano- and microstructures as a constituent of wound-dressing formulations is highlighted. |
---|---|
MeSH term(s) | Biocompatible Materials/pharmacology ; Biocompatible Materials/therapeutic use ; Indoles/chemistry ; Indoles/pharmacology ; Polymers/pharmacology ; Polymers/therapeutic use ; Wound Healing |
Chemical Substances | Biocompatible Materials ; Indoles ; Polymers ; polydopamine |
Language | English |
Publishing date | 2022-06-01 |
Publishing country | United States |
Document type | Journal Article ; Review |
ISSN | 2373-9878 |
ISSN (online) | 2373-9878 |
DOI | 10.1021/acsbiomaterials.1c01436 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Inter-library loan at ZB MED
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.