LIVIVO - Search results -

Search results

Result 1 - 10 of total 95

Search options

Article ; Online: Pharmacological Effects and Clinical Prospects of Cepharanthine.

Liang, Di / Li, Qi / Du, Lina / Dou, Guifang

2022 Volume 27, Issue 24

Abstract: Cepharanthine is an active ingredient separated and extracted ... ...

Abstract	Cepharanthine is an active ingredient separated and extracted from
Language	English
Publishing date	2022-12-15
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules27248933
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Effects of UV-based oxidation processes on the degradation of microplastic: Fragmentation, organic matter release, toxicity and disinfection byproduct formation.

Du, Zhenqi / Li, Guifang / Ding, Shunke / Song, Wuchang / Zhang, Mengyu / Jia, Ruibao / Chu, Wenhai

Water research

2023 Volume 237, Page(s) 119983

Abstract: The occurrence and transformation of microplastics (MPs) remaining in the water treatment plants has recently attracted considerable attention. However, few efforts have been made to investigate the behavior of dissolved organic matter (DOM) derived from ...

Abstract	The occurrence and transformation of microplastics (MPs) remaining in the water treatment plants has recently attracted considerable attention. However, few efforts have been made to investigate the behavior of dissolved organic matter (DOM) derived from MPs during oxidation processes. In this study, the characteristics of DOM leached from MPs during typical ultraviolet (UV)-based oxidation was focused on. The toxicity and disinfection byproduct (DBP) formation potentials of MP-derived DOM were further investigated. Overall, UV-based oxidation significantly enhanced the aging and fragmentation of highly hydroscopic MPs. The mass scales of leachates to MPs increased from 0.03% - 0.18% at initial stage to 0.09% - 0.71% after oxidation, which were significantly higher than those leached by natural light exposure. Combined fluorescence analysis with high resolution mass spectrometer scan confirmed that the dominant MP-derived DOM are chemical additives. PET-derived DOM and PA6-derived DOM showed inhibition of Vibrio fischeri activity with corresponding EC
MeSH term(s)	Disinfection/methods ; Microplastics ; Plastics ; Chlorella vulgaris ; Halogens ; Halogenation ; Water Purification ; Water Pollutants, Chemical/analysis
Chemical Substances	Microplastics ; Plastics ; Halogens ; Water Pollutants, Chemical
Language	English
Publishing date	2023-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2023.119983
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 78/260: Show issues
Z 3381: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Design and Construction of Carbon-Coated Fe

Liu, Huan / Zhang, Weibin / Wang, Weili / Han, Guifang / Zhang, Jingde / Zhang, Shiwei / Wang, Jianchuan / Du, Yong

Small (Weinheim an der Bergstrasse, Germany)

2023 Volume 19, Issue 52, Page(s) e2304264

Abstract: Transition metal oxides, highly motivated anodes for lithium-ion batteries due to high theoretical capacity, typically afflict by inferior conductivity and significant volume variation. Architecting heterogeneous structures with distinctive interfacial ... ...

Abstract	Transition metal oxides, highly motivated anodes for lithium-ion batteries due to high theoretical capacity, typically afflict by inferior conductivity and significant volume variation. Architecting heterogeneous structures with distinctive interfacial features can effectively regulate the electronic structure to favor electrochemical properties. Herein, an engineered carbon-coated nanosized Fe
Language	English
Publishing date	2023-09-03
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202304264
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Effects of UV-based oxidation processes on the degradation of microplastic: fragmentation, organic matter release, toxicity and disinfection byproduct formation

Du, Zhenqi / Li, Guifang / Ding, Shunke / Song, Wuchang / Zhang, Mengyu / Jia, Ruibao / Chu, Wenhai

Water Research. 2023 Apr. 18, p.119983-

2023 , Page(s) 119983–

Abstract	The occurrence and transformation of microplastics (MPs) remaining in the water treatment plants has recently attracted considerable attention. However, few efforts have been made to investigate the behavior of dissolved organic matter (DOM) derived from MPs during oxidation processes. In this study, the characteristics of DOM leached from MPs during typical ultraviolet (UV)-based oxidation was focused on. The toxicity and disinfection byproduct (DBP) formation potentials of MP-derived DOM were further investigated. Overall, UV-based oxidation significantly enhanced the aging and fragmentation of highly hydroscopic MPs. The mass scales of leachates to MPs increased from 0.03% - 0.18% at initial stage to 0.09% - 0.71% after oxidation, which were significantly higher than those leached by natural light exposure. Combined fluorescence analysis with high resolution mass spectrometer scan confirmed that the dominant MP-derived DOM are chemical additives. PET-derived DOM and PA6-derived DOM showed inhibition of Vibrio fischeri activity with corresponding EC₅₀ of 2.84 mg/L and 4.58 mg/L of DOC. Bioassay testing with Chlorella vulgaris and Microcystis aeruginosa showed that high concentrations of MP-derived DOM inhibited algal growth by disrupting the cell membrane permeability and integrity. MP-derived DOM had a similar chlorine consumption (1.63 ± 0.41 mg/DOC) as surface water (1.0 - 2.0 mg/DOC), and MP-derived DOM mainly served as precursors for the investigated DBPs. Contrary to the results of previous studies, the DBP yields from MP-derived DOM were relatively lower than those of aquatic DOM under simulated distribution system conditions. This suggests that MP-derived DOM itself rather than serving as DBP precursor might be potential toxic concern.
Keywords	Chlorella vulgaris ; Microcystis aeruginosa ; Vibrio fischeri ; algae ; bioassays ; byproducts ; chlorine ; disinfection ; dissolved organic matter ; fluorescence ; membrane permeability ; microplastics ; oxidation ; research ; solar radiation ; spectrometers ; surface water ; toxicity ; water treatment ; Microplastic ; advanced oxidation processes ; disinfection byproducts
Language	English
Dates of publication	2023-0418
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2023.119983
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 78/260: Show issues
Z 3381: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Cepharanthine Dry Powder Inhaler for the Treatment of Acute Lung Injury.

Liang, Di / Wang, Wanmei / Chen, Guangrui / Li, Jian / Dou, Guifang / Gan, Hui / Han, Peng / Du, Lina / Gu, Ruolan

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 11

Abstract: Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) induces a severe cytokine storm that may cause acute lung injury/acute respiratory distress syndrome (ALI/ARDS) with high clinical morbidity and mortality in infected individuals. Cepharanthine ...

Abstract	Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) induces a severe cytokine storm that may cause acute lung injury/acute respiratory distress syndrome (ALI/ARDS) with high clinical morbidity and mortality in infected individuals. Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid isolated and extracted from
MeSH term(s)	Rats ; Animals ; Administration, Inhalation ; Dry Powder Inhalers ; COVID-19/metabolism ; SARS-CoV-2 ; Respiratory Aerosols and Droplets ; Lung/metabolism ; Acute Lung Injury/drug therapy ; Acute Lung Injury/metabolism ; Benzylisoquinolines/pharmacology ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/analysis ; Particle Size ; Powders/analysis
Chemical Substances	cepharanthine (7592YJ0J6T) ; Benzylisoquinolines ; Anti-Inflammatory Agents ; Powders
Language	English
Publishing date	2023-05-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28114441
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Cepharanthine Dry Powder Inhaler for the Treatment of Acute Lung Injury

Di Liang / Wanmei Wang / Guangrui Chen / Jian Li / Guifang Dou / Hui Gan / Peng Han / Lina Du / Ruolan Gu

Molecules, Vol 28, Iss 4441, p

2023 Volume 4441

Abstract	Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) induces a severe cytokine storm that may cause acute lung injury/acute respiratory distress syndrome (ALI/ARDS) with high clinical morbidity and mortality in infected individuals. Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid isolated and extracted from Stephania cepharantha Hayata . It exhibits various pharmacological effects, including antioxidant, anti-inflammatory, immunomodulatory, anti-tumor, and antiviral activities. The low oral bioavailability of CEP can be attributed to its poor water solubility. In this study, we utilized the freeze-drying method to prepare dry powder inhalers (DPI) for the treatment of acute lung injury (ALI) in rats via pulmonary administration. According to the powder properties study, the aerodynamic median diameter (D a ) of the DPIs was 3.2 μm, and the in vitro lung deposition rate was 30.26; thus, meeting the Chinese Pharmacopoeia standard for pulmonary inhalation administration. We established an ALI rat model by intratracheal injection of hydrochloric acid (1.2 mL/kg, pH = 1.25). At 1 h after the model’s establishment, CEP dry powder inhalers (CEP DPIs) (30 mg/kg) were sprayed into the lungs of rats with ALI via the trachea. Compared with the model group, the treatment group exhibited a reduced pulmonary edema and hemorrhage, and significantly reduced content of inflammatory factors (TNF-α, IL-6 and total protein) in their lungs ( p < 0.01), indicating that the main mechanism of CEP underlying the treatment of ALI is anti-inflammation. Overall, the dry powder inhaler can deliver the drug directly to the site of the disease, increasing the intrapulmonary utilization of CEP and improving its efficacy, making it a promising inhalable formulation for the treatment of ALI.
Keywords	cepharanthine ; pulmonary drug delivery ; acute lung injury ; dry powder inhalers ; Organic chemistry ; QD241-441
Subject code	610
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Light Addressable Potentiometric Sensors for Biochemical Imaging on Microscale

Jiezhang Luo / Shibin Liu / Yinhao Chen / Jie Tan / Wenbo Zhao / Yun Zhang / Guifang Li / Yongqian Du / Yaoxin Zheng / Xueliang Li / Huijuan Li / Yue Tan

ACS Omega, Vol 8, Iss 45, Pp 42028-

A Review on Optimization of Imaging Speed and Spatial Resolution

2023 Volume 42044

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Effects of aerobic exercise or Tai Chi Chuan interventions on problematic mobile phone use and the potential role of intestinal flora: A multi-arm randomized controlled trial.

Zhang, Kexin / Guo, Haiyun / Zhang, Xueqing / Yang, Huayu / Yuan, Guojing / Zhu, Zhihui / Lu, Xiaoyan / Zhang, Jianghui / Du, Jun / Shi, Haiyan / Jin, Guifang / Ren, Juan / Hao, Jiahu / Sun, Ying / Su, Puyu / Zhang, Zhihua

Journal of psychiatric research

2024 Volume 170, Page(s) 394–407

Abstract: Background: Problematic use of mobile phones (PMPU) has been described as a serious public health issue.: Methods: This study was a parallel three-arm randomized controlled trial and has completed registration (ClinicalTrials.gov Identifier: ... ...

Abstract	Background: Problematic use of mobile phones (PMPU) has been described as a serious public health issue. Methods: This study was a parallel three-arm randomized controlled trial and has completed registration (ClinicalTrials.gov Identifier: NCT05843591). Ninety college students with PMPU were randomly assigned to the aerobic exercise group (AE group, n = 30), the Tai Chi Chuan group (TCC group, n = 30), or the wait-list control group (WLC group, n = 30). At the end of the intervention, stool samples from the study participants were collected for biological analysis based on 16 S rDNA amplicon sequencing technology. The primary outcome was addiction symptoms assessed by the Smartphone Addiction Scale-Short Version (SAS-SV). The secondary outcomes are emotional symptoms, physical symptoms, and flora species. Results: Compared with the WLC group, the AE and TCC groups showed reductions in PMPU levels, physical and mental fatigue, but there was no difference between the two groups. Moreover, the effect of increasing self-esteem embodied in the TCC group was not present in the AE group. Compared to the WLC group, the relative abundance of Bacteroidaceae and Bacteroides were lower in the AE group, while the relative abundance of Erysipelotrichaceae and Alistipes were lower in the TCC group. And the relative abundance of Bacteroidaceae, Bacteroides, and Alistipes were significantly and negatively correlated with the decline in PMPU scores. Conclusion: AE or TCC is an effective, safe and efficient intervention for college students with PMPU, providing some physiological and psychological benefits and having some impact on their intestinal flora.
MeSH term(s)	Humans ; Tai Ji ; Cell Phone Use ; Gastrointestinal Microbiome ; Exercise ; Students/psychology
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	3148-3
ISSN	1879-1379 ; 0022-3956
ISSN (online)	1879-1379
ISSN	0022-3956
DOI	10.1016/j.jpsychires.2024.01.012
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui I Zs.243: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Light Addressable Potentiometric Sensors for Biochemical Imaging on Microscale: A Review on Optimization of Imaging Speed and Spatial Resolution.

Luo, Jiezhang / Liu, Shibin / Chen, Yinhao / Tan, Jie / Zhao, Wenbo / Zhang, Yun / Li, Guifang / Du, Yongqian / Zheng, Yaoxin / Li, Xueliang / Li, Huijuan / Tan, Yue

ACS omega

2023 Volume 8, Issue 45, Page(s) 42028–42044

Abstract: Light addressable potentiometric sensors (LAPS) are a competitive tool for unmarked biochemical imaging, especially imaging on microscale. It is essential to optimize the imaging speed and spatial resolution of LAPS since the imaging targets of LAPS, ... ...

Abstract	Light addressable potentiometric sensors (LAPS) are a competitive tool for unmarked biochemical imaging, especially imaging on microscale. It is essential to optimize the imaging speed and spatial resolution of LAPS since the imaging targets of LAPS, such as cell, microfluidic channel, etc., require LAPS to image at the micrometer level, and a fast enough imaging speed is a prerequisite for the dynamic process involved in biochemical imaging. In this study, we discuss the improvement of LAPS in terms of imaging speed and spatial resolution. The development of LAPS in imaging speed and spatial resolution is demonstrated by the latest applications of biochemistry monitoring and imaging on the microscale.
Language	English
Publishing date	2023-11-03
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c04789
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Inhibitory effects of catalpol on DNCB-induced atopic dermatitis and IgE-mediated mast cells reaction.

Sun, Yun / Zhu, Defen / Qu, Lu / Li, Manping / Du, Wenxia / Wang, Mingming / Zhang, Yi / Chen, Guifang / Rao, Gaoxiong / Yu, Xiaoling / Wu, Xiangnong / Huang, Feng / Tong, Xiaoyun

International immunopharmacology

2023 Volume 126, Page(s) 111274

Abstract: Atopic dermatitis (AD) is a chronic, inflammatory cutaneous disease driven by immune dysregulation. Catalpol is an iridoids, possessing anti-inflammatory, antioxidant, and neuroprotective activities. It can be added to food as a dietary supplement. To ... ...

Abstract	Atopic dermatitis (AD) is a chronic, inflammatory cutaneous disease driven by immune dysregulation. Catalpol is an iridoids, possessing anti-inflammatory, antioxidant, and neuroprotective activities. It can be added to food as a dietary supplement. To evaluate the effects and mechanisms of catalpol on AD, both in vitro and in vivo studies were conducted. It was found that catalpol downregulated the phosphorylation of Lyn and Syk to inhibit various downstream pathways, including intracellular Ca
MeSH term(s)	Mice ; Animals ; Dermatitis, Atopic/chemically induced ; Dermatitis, Atopic/drug therapy ; Mast Cells ; Dinitrochlorobenzene ; Immunoglobulin E/metabolism ; Skin ; Cytokines/metabolism ; Mice, Inbred BALB C
Chemical Substances	catalpol (2415-24-9) ; Dinitrochlorobenzene ; Immunoglobulin E (37341-29-0) ; Cytokines
Language	English
Publishing date	2023-12-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2043785-7
ISSN	1878-1705 ; 1567-5769
ISSN (online)	1878-1705
ISSN	1567-5769
DOI	10.1016/j.intimp.2023.111274
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5408: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito