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  1. Article ; Online: Reply to Argiri Sianou, George Galyfos and Georgios Kaparos' Letter to the Editor re: Alan J. Wolfe, Linda Brubaker. "Sterile Urine" and the Presence of Bacteria. Eur Urol 2015;68:173-4.

    Wolfe, Alan J / Brubaker, Linda

    European urology

    2016  Volume 69, Issue 1, Page(s) e8–9

    MeSH term(s) Bacteria/isolation & purification ; Bacteriological Techniques ; Female ; Humans ; Microbiota ; Urinary Bladder/microbiology ; Urinary Incontinence/microbiology ; Urinary Tract Infections/microbiology ; Urine/microbiology
    Language English
    Publishing date 2016-01
    Publishing country Switzerland
    Document type Comment ; Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2015.06.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1247: Show issues Location:
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    Zs.MO 294: Show issues

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  2. Book: The second messenger cyclic Di GMP

    Wolfe, Alan J.

    2010  

    Title variant The second messenger cyclic Di-GMP
    Author's details ed. by Alan J. Wolfe
    Keywords Cyclic GMP / physiology ; Cyclic GMP / analogs & derivatives ; Signal Transduction / physiology ; Bacterial Physiological Phenomena ; Genome, Bacterial
    Language English
    Size XI, 344 S. : Ill., graph. Darst.
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT016183901
    ISBN 978-1-55581-499-1 ; 1-55581-499-9
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2010 A 1259 order for loan Magazin

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  3. Article ; Online: Complete genome sequences of

    Choi, Brian I / Fontes Noronha, Melline / Kaindl, Jacob / Wolfe, Alan J

    Microbiology resource announcements

    2024  , Page(s) e0015624

    Abstract: Previously identified under the single designation ... ...

    Abstract Previously identified under the single designation of
    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00156-24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Urine microbiome in individuals with an impaired immune system.

    Elsayed, Noha S / Wolfe, Alan J / Burk, Robert D

    Frontiers in cellular and infection microbiology

    2024  Volume 13, Page(s) 1308665

    Abstract: With the advent of next generation sequencing, it is now appreciated that human urine is not sterile. Recent investigations of the urinary microbiome (urobiome) have provided insights into several urological diseases. Urobiome dysbiosis, defined as non- ... ...

    Abstract With the advent of next generation sequencing, it is now appreciated that human urine is not sterile. Recent investigations of the urinary microbiome (urobiome) have provided insights into several urological diseases. Urobiome dysbiosis, defined as non-optimal urine microbiome composition, has been observed in many disorders; however, it is not clear whether this dysbiosis is the cause of urinary tract disorders or a consequence. In addition, immunologically altered disorders are associated with higher rates of urinary tract infections. These disorders include immunoproliferative and immunodeficiency diseases, cancer, and immunosuppressant therapy in transplant recipients. In this review, we examine the current state of knowledge of the urobiome in immunologically altered diseases, its composition and metabolomic consequences. We conclude that more data are required to describe the urobiome in immune altered states, knowledge that could facilitate understanding the role of the urobiome and its pathophysiological effects on urinary tract infections and other disorders of the urinary tract.
    MeSH term(s) Humans ; Dysbiosis ; Urinary Tract ; Microbiota ; Urinary Tract Infections ; Immune System
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1308665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Microbiome of Male Infertility: Paving the Road Ahead.

    Bajic, Petar / Wolfe, Alan J

    European urology

    2021  Volume 79, Issue 6, Page(s) 837–838

    MeSH term(s) Humans ; Infertility, Male/therapy ; Male ; Microbiota ; Occupational Exposure
    Language English
    Publishing date 2021-02-16
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.02.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 294: Show issues

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  6. Article ; Online: Exploring the genotypic and phenotypic differences distinguishing

    Ene, Adriana / Banerjee, Swarnali / Wolfe, Alan J / Putonti, Catherine

    mSphere

    2023  Volume 8, Issue 4, Page(s) e0056222

    Abstract: Lactobacillus ... ...

    Abstract Lactobacillus crispatus
    MeSH term(s) Female ; Humans ; Vagina ; RNA, Ribosomal, 16S/genetics ; Maltose ; Lactobacillus/genetics ; Genotype
    Chemical Substances RNA, Ribosomal, 16S ; Maltose (69-79-4)
    Language English
    Publishing date 2023-06-27
    Publishing country United States
    Document type Journal Article
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00562-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Urinary Plasmids Reduce Permissivity to Coliphage Infection.

    Montelongo Hernandez, Cesar / Putonti, Catherine / Wolfe, Alan J

    Microbiology spectrum

    2023  Volume 11, Issue 4, Page(s) e0130923

    Abstract: The microbial community of the urinary tract (urinary microbiota or urobiota) has been associated with human health. Bacteriophages (phages) and plasmids present in the urinary tract, like in other niches, may shape urinary bacterial dynamics. While ... ...

    Abstract The microbial community of the urinary tract (urinary microbiota or urobiota) has been associated with human health. Bacteriophages (phages) and plasmids present in the urinary tract, like in other niches, may shape urinary bacterial dynamics. While urinary Escherichia coli strains associated with urinary tract infection (UTI) and their phages have been catalogued for the urobiome, bacterium-plasmid-phage interactions have yet to be explored. In this study, we characterized urinary E. coli plasmids and their ability to decrease permissivity to E. coli phage (coliphage) infection. Putative F plasmids were predicted in 47 of 67 urinary E. coli isolates, and most of these plasmids carried genes that encode toxin-antitoxin (TA) modules, antibiotic resistance, and/or virulence. Urinary E. coli plasmids, from urinary microbiota strains UMB0928 and UMB1284, were conjugated into E. coli K-12 strains. These transconjugants included genes for antibiotic resistance and virulence, and they decreased permissivity to coliphage infection by the laboratory phage P1vir and the urinary phages Greed and Lust. Plasmids in one transconjugant were maintained in E. coli K-12 for up to 10 days in the absence of antibiotic resistance selection; this included the maintenance of the antibiotic resistance phenotype and decreased permissivity to phage. Finally, we discuss how F plasmids present in urinary E. coli strains could play a role in coliphage dynamics and the maintenance of antibiotic resistance in urinary E. coli.
    MeSH term(s) Humans ; Escherichia coli/genetics ; Plasmids/genetics ; Coliphages/genetics ; Bacteriophages/genetics ; Escherichia coli Infections/microbiology ; Urinary Tract ; Bacteria/genetics ; Anti-Bacterial Agents
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01309-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Profiling the plasmid conjugation potential of urinary

    Montelongo Hernandez, Cesar / Putonti, Catherine / Wolfe, Alan J

    Microbial genomics

    2022  Volume 8, Issue 5

    Abstract: Escherichia ... ...

    Abstract Escherichia coli
    MeSH term(s) Escherichia coli ; Escherichia coli Infections/microbiology ; Female ; Humans ; Male ; Plasmids/genetics ; Urinary Tract Infections/microbiology
    Language English
    Publishing date 2022-05-25
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2835258-0
    ISSN 2057-5858 ; 2057-5858
    ISSN (online) 2057-5858
    ISSN 2057-5858
    DOI 10.1099/mgen.0.000814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Draft Genome Sequence of Staphylococcus epidermidis UMB7543, Isolated from a Female Patient with Recurrent Urinary Tract Infections.

    Jablonska, Sandra / Wolfe, Alan J / Putonti, Catherine

    Microbiology resource announcements

    2022  Volume 11, Issue 12, Page(s) e0096222

    Abstract: Staphylococcus epidermidis is a Gram-positive bacterium that is part of the normal human flora, found in multiple anatomical sites. Here, we present the 2.6-Mbp draft genome sequence of S. epidermidis UMB7543, isolated from a catheterized urine sample ... ...

    Abstract Staphylococcus epidermidis is a Gram-positive bacterium that is part of the normal human flora, found in multiple anatomical sites. Here, we present the 2.6-Mbp draft genome sequence of S. epidermidis UMB7543, isolated from a catheterized urine sample from a female patient with a documented diagnosis of recurrent urinary tract infection.
    Language English
    Publishing date 2022-11-10
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00962-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Microbiologist in the clinic: coitally related symptoms with negative urine cultures.

    Brubaker, Linda / Horsley, Harry / Khasriya, Rajvinder / Wolfe, Alan J

    International urogynecology journal

    2023  Volume 34, Issue 11, Page(s) 2701–2704

    Abstract: In this first episode of the Microbiologist in the Clinic series, clinicians and laboratory scientists share their perspectives about a 30 y/o woman, who is seeking specialty consultation for frequent episodes of urinary urgency, frequency, and dysuria, ... ...

    Abstract In this first episode of the Microbiologist in the Clinic series, clinicians and laboratory scientists share their perspectives about a 30 y/o woman, who is seeking specialty consultation for frequent episodes of urinary urgency, frequency, and dysuria, which respond to short courses of antibiotics. Although her home dipsticks suggest that she has a UTI, and her urinalysis typically has a moderate number of white blood cells, her urine cultures are always negative. The challenges of this clinical presentation are discussed with evidence for evaluation and treatment.
    MeSH term(s) Humans ; Female ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/drug therapy ; Urinalysis ; Anti-Bacterial Agents/therapeutic use ; Dysuria ; Urination Disorders ; Urine
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-023-05662-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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