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  1. Book: Risiken und Nebenwirkungen von Psychotherapie

    Freyberger, Harald J. / Linden, Michael / Strauß, Bernhard

    Erfassung, Bewältigung, Risikovermeidung

    2018  

    Author's details Michael Linden, Bernhard Strauß (Hrsg.) ; mit Beiträgen von H.J. Freyberger [und 18 anderen]
    Keywords Psychotherapie ; Nebenwirkung ; Risiko ; Therapieerfolg
    Subject Behandlung ; Psychologische Behandlung ; Therapie ; Behandlungserfolg ; Heilungserfolg ; Heilerfolg
    Language German
    Size XIII, 201 Seiten, Illustration
    Edition 2., aktualisierte Auflage
    Publisher Medizinisch Wissenschaftliche Verlagsgesellschaft
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT019805656
    ISBN 978-3-95466-400-9 ; 3-95466-400-3
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Trajectories of relationship and sexual satisfaction over 2 years in the Covid-19 pandemic: A latent class analysis.

    Vigl, Julia / Strauß, Hannah / Talamini, Francesca / Zentner, Marcel

    Journal of personality

    2024  

    Abstract: Objective: Previous research on the impact of the Covid-19 pandemic on romantic relationships has mainly concentrated on short-term effects and average trends of change. This study aimed to explore different trajectories of relationship and sexual ... ...

    Abstract Objective: Previous research on the impact of the Covid-19 pandemic on romantic relationships has mainly concentrated on short-term effects and average trends of change. This study aimed to explore different trajectories of relationship and sexual satisfaction from April 2020 to March 2022.
    Method: Including a cross-national sample of 2859 individuals, a latent class approach was applied to identify subgroups of sexual and relationship satisfaction trajectories. Participants' satisfaction levels, attachment style, psychological symptoms, life satisfaction, and living arrangements were taken into account.
    Results: Three latent classes were identified for both relationship and sexual satisfaction: (1) a group with high satisfaction levels but a slightly declining trajectory, (2) a group with low satisfaction levels but an ascending trajectory, and (3) a fluctuating group. Living apart, having children, psychological symptoms, low life satisfaction, and avoidant attachment characterized the two groups with low or fluctuating trajectories.
    Conclusions: The findings suggest that there were different trajectories of relationship and sexual satisfaction during the pandemic, which can be predicted by individual dispositions. Even 2 years after the pandemic, its effects had not disappeared.
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 420745-2
    ISSN 1467-6494 ; 0022-3506
    ISSN (online) 1467-6494
    ISSN 0022-3506
    DOI 10.1111/jopy.12928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vibration receptor organs in the insect leg: neuroanatomical diversity and functional principles.

    Strauß, Johannes / Stritih-Peljhan, Nataša / Nishino, Hiroshi

    Current opinion in insect science

    2023  Volume 61, Page(s) 101153

    Abstract: Detecting substrate vibrations is essential for insects in different behavioural contexts. These vibrational behaviours are mediated by mechanoreceptor organs detecting and processing vibrational stimuli transmitted in the environment. We discuss ... ...

    Abstract Detecting substrate vibrations is essential for insects in different behavioural contexts. These vibrational behaviours are mediated by mechanoreceptor organs detecting and processing vibrational stimuli transmitted in the environment. We discuss recently gained insights about the functional principles of insect vibration receptors, mainly leg chordotonal organs highly sensitive to vibrational stimuli, and the mechanisms of their diversification in neuroanatomy and functional morphology, in relation to the attachment structures and mechanical coupling. The two main input pathways for vibration stimuli transferred by the insect legs to vibrosensory organs via the cuticle and via the hemolymph are fundamental for explaining sensory specialisations. The vibroreceptor organs can diversify in their neuroanatomy and morphology in several key aspects. This provides the structural basis for complex adaptations in sensory evolution.
    MeSH term(s) Animals ; Vibration ; Neuroanatomy ; Sensory Receptor Cells ; Insecta/physiology
    Language English
    Publishing date 2023-12-19
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2772833-X
    ISSN 2214-5753 ; 2214-5745
    ISSN (online) 2214-5753
    ISSN 2214-5745
    DOI 10.1016/j.cois.2023.101153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Chronische Rhinosinusitis mit Polyposis nasi : Retrospektive Analyse des therapeutischen Vorgehens bei 463 Patienten.

    Strauss, J / Lochbaum, R / Hoffmann, T K / Mayer, B / Appel, H / Hahn, J

    HNO

    2024  

    Abstract: Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial inflammatory disease, the treatment of which has undergone significant changes in recent years. In addition to surgical approaches, topical and systemic steroids, and ... ...

    Title translation Chronic rhinosinusitis with nasal polyposis : A retrospective analysis of therapeutic approaches in 463 patients.
    Abstract Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial inflammatory disease, the treatment of which has undergone significant changes in recent years. In addition to surgical approaches, topical and systemic steroids, and adaptive acetylsalicylic acid (ASA) desensitization, three specific antibodies have complemented the therapeutic portfolio since 2019.
    Methods: A retrospective evaluation of all patients who presented as outpatients for the first time due to CRSwNP in 2007 and 2008 (collective A) and 2017 and 2018 (collective B) was performed, up to and including June 2023.
    Results: The clinical courses of 463 patients (mean age 49.1 years, range 5-82 years; 65.9% male) were included in the analysis. Conservative treatment with nasal corticosteroids started before initial presentation was more frequent in collective B (collective A 43.9% vs. collective B 72.2%). In 278 of the 463 patients (60%; A: 62%, B: 58%), at least one operation on the nasal sinuses had been performed after initial presentation; in 101 of these patients (36.3%) recurrent polyposis (within mean follow-up of 2.4 years) required further treatment. The indication for ASA provocation/desensitization was applied less frequently in collective B, also due to a high discontinuation rate (at least 38%) of the maintenance therapy. Of the total cohort, 16 patients (3.5%; A: n = 8, B: n = 8) were meanwhile switched to antibody therapy at recurrence.
    Conclusion: A step-by-step guideline-orientated approach is recommended in the treatment of CRSwNP. Systemic antibodies as an add-on to nasal corticosteroids are a relatively new therapeutic option for treatment-refractory CRSwNP, which reduces the indication for ASA desensitization, which is associated with a relatively high incidence of side effects and poor compliance.
    Language German
    Publishing date 2024-05-03
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 200040-4
    ISSN 1433-0458 ; 0017-6192
    ISSN (online) 1433-0458
    ISSN 0017-6192
    DOI 10.1007/s00106-024-01479-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Real-World Evidence for Causal Inference-Are We Ready?

    Strauss, Martin H / Narkiewicz, Krzysztof / Lavie, Carl J / Masi, Stefano

    Mayo Clinic proceedings

    2023  Volume 98, Issue 12, Page(s) 1890–1892

    Language English
    Publishing date 2023-12-01
    Publishing country England
    Document type Letter
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: In Memoriam: Barry Zaret-A Life Well Lived, A Guiding Beacon, A Paragon to Follow.

    Leppo, Jeffrey / Strauss, H William / Narula, Jagat

    Journal of the American College of Cardiology

    2023  Volume 81, Issue 4, Page(s) 425–427

    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.12.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Long-Term Efficacy and Safety Among Patients With Severe Eosinophilic Asthma Treated With Mepolizumab and Its Effect on Small Airways.

    Strauss, Ronald / Leflein, Hannah / Kolesar, Anna / Hammel, Jeffrey

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 12, Page(s) 3670–3679.e2

    Abstract: Background: The major problem at the Cleveland Allergy and Asthma Center was the need for additional therapy for severe eosinophilic asthma patients who were steroid-dependent or required frequent bursts of prednisone.: Objectives: The objectives of ... ...

    Abstract Background: The major problem at the Cleveland Allergy and Asthma Center was the need for additional therapy for severe eosinophilic asthma patients who were steroid-dependent or required frequent bursts of prednisone.
    Objectives: The objectives of this study were to determine the efficacy of monthly mepolizumab (MP) injections up to 6½ years using Asthma Control Quesitonnaire-7 (ACQ-7), forced expiratory volume in 1 second (FEV
    Methods: We reviewed the charts of 67 patients with severe eosinophilic asthma and compared the results between 47 super-responders and the rest of the cohort regarding ACQ-6, ACQ-7, eosinophils, FEV
    Results: After 6½ years, there were no significant changes in FEV
    Conclusions: The use of MP up to 6½ years was safe and effective, with significant changes to ACQ-7 and FEF
    MeSH term(s) Humans ; Anti-Asthmatic Agents ; Asthma ; Antibodies, Monoclonal, Humanized/adverse effects ; Pulmonary Eosinophilia/drug therapy ; Forced Expiratory Volume ; Treatment Outcome
    Chemical Substances mepolizumab (90Z2UF0E52) ; Anti-Asthmatic Agents ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.08.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Current State of Synovial Fluid Biomarkers in Sports Medicine.

    Markus, Danielle H / Berlinberg, Elyse J / Strauss, Eric J

    JBJS reviews

    2021  Volume 9, Issue 8

    Abstract: While the gross mechanical abnormalities contributing to posttraumatic osteoarthritis (PTOA) have been well described, new research is demonstrating that these insults to the articular cartilage may also initiate changes in the joint microenvironment ...

    Abstract »: While the gross mechanical abnormalities contributing to posttraumatic osteoarthritis (PTOA) have been well described, new research is demonstrating that these insults to the articular cartilage may also initiate changes in the joint microenvironment that seed the development of PTOA.
    »: A growing amount of literature has identified key biomarkers that exhibit altered expression in the synovial fluid following a knee injury, with a portion of these molecules remaining elevated in the years following an injury.
    »: These biomarkers have the potential to aid in the early detection of PTOA before radiographic evidence becomes apparent. Furthermore, deciphering the processes that occur within the articular microenvironment after trauma may allow for better identification of therapeutic targets for the prevention and earlier treatment of PTOA.
    MeSH term(s) Biomarkers ; Cartilage, Articular/diagnostic imaging ; Humans ; Osteoarthritis ; Sports Medicine ; Synovial Fluid
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Journal Article
    ISSN 2329-9185
    ISSN (online) 2329-9185
    DOI e21.00024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Less Is More: Developments in Nanotechnology for Antirestenosis Therapies.

    Trepanier, Chantal M / Burke-Kleinman, Jonah / Strauss, Bradley H / Santerre, J Paul / Bendeck, Michelle P

    Arteriosclerosis, thrombosis, and vascular biology

    2023  Volume 43, Issue 7, Page(s) 1096–1110

    Abstract: Despite recent advancements in vascular disease treatments, thrombosis and poor long-term vessel patency remain significant barriers to effective endovascular intervention. Current balloon angioplasty and stenting techniques effectively restore acute ... ...

    Abstract Despite recent advancements in vascular disease treatments, thrombosis and poor long-term vessel patency remain significant barriers to effective endovascular intervention. Current balloon angioplasty and stenting techniques effectively restore acute blood flow in occluded vessels but have persistent limitations. Damage to the arterial endothelium caused by injury during catheter tracking triggers neointimal hyperplasia and the release of proinflammatory factors leading to increased risk of thrombosis and restenosis. Antirestenotic agents commonly delivered on angioplasty balloons and stents have lowered arterial restenosis rates, but the absence of cell type selectivity significantly delays critical endothelium repair. Targeted delivery of biomolecular therapeutics, coupled with engineered nanoscale excipients, has the potential to redefine cardiovascular interventions by improving long-term efficacy, limiting off-target effects, and reducing costs compared with conventional clinical standards of care. This review analyzes current forms of localized vascular drug delivery, emerging nanoscale therapeutic and excipient strategies, and provides recommendations for future areas of study to advance the treatment of vascular disease through innovations in nanotechnology.
    MeSH term(s) Humans ; Angioplasty, Balloon/adverse effects ; Angioplasty, Balloon/methods ; Stents ; Constriction, Pathologic/etiology ; Vascular Diseases/etiology ; Thrombosis/etiology ; Nanotechnology ; Treatment Outcome
    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1221433-4
    ISSN 1524-4636 ; 1079-5642
    ISSN (online) 1524-4636
    ISSN 1079-5642
    DOI 10.1161/ATVBAHA.123.318450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Emergency Department-Based Physical Function Measures for Falls in Older Adults and Outcomes: A Secondary Analysis of GAPcare.

    Strauss, Daniel H / Davoodi, Natalie M / Resnik, Linda J / Keene, Sarah / Serina, Peter T / Goldberg, Elizabeth M

    Journal of geriatric physical therapy (2001)

    2024  

    Abstract: Background and purpose: Falls are the leading reason for injury-related emergency department (ED) visits for older adults. The Geriatric Acute and Post-acute Fall Prevention Intervention (GAPcare), an in-ED intervention combining a medication therapy ... ...

    Abstract Background and purpose: Falls are the leading reason for injury-related emergency department (ED) visits for older adults. The Geriatric Acute and Post-acute Fall Prevention Intervention (GAPcare), an in-ED intervention combining a medication therapy management session delivered by a pharmacist and a fall risk assessment and plan by a physical therapist, reduced ED revisits at 6 months among older adults presenting after a fall. Our objective was to evaluate the relationship between measures of function obtained in the ED and clinical outcomes.
    Methods: This was a secondary analysis of data from GAPcare, a randomized controlled trial conducted from January 2018 to October 2019 at 2 urban academic EDs. Standardized measures of function (Timed Up and Go [TUG] test, Barthel Activity of Daily Living [ADL], Activity Measure for Post Acute Care [AM-PAC] 6 clicks) were collected at the ED index visit. We performed a descriptive analysis and hypothesis testing (chi square test and analysis of variance) to assess the relationship of functional measures with outcomes (ED disposition, ED revisits for falls, and place of residence at 6 months). Emergency department disposition status refers to discharge location immediately after the ED evaluation is complete (eg, hospital admission, original residence, skilled nursing facility).
    Results and discussion: Among 110 participants, 55 were randomized to the GAPcare intervention and 55 received usual care. Of those randomized to the intervention, 46 received physical therapy consultation. Median age was 81 years; participants were predominantly women (67%) and White (94%). Seventy-three (66%) were discharged to their original residence, 14 (13%) were discharged to a skilled nursing facility and 22 (20%) were admitted. There was no difference in ED disposition status by index visit Barthel ADLs (P = .371); however, TUG times were faster (P = .016), and AM-PAC 6 clicks score was higher among participants discharged to their original residence (P ≤ .001). Participants with slower TUG times at the index ED visit were more likely to reside in nursing homes by six months (P = .002), while Barthel ADL and AM-PAC 6 clicks did not differ between those residing at home and other settings.
    Conclusions: Measures of function collected at the index ED visit, such as the AM-PAC 6 clicks and TUG time, may be helpful at predicting clinical outcomes for older adults presenting for a fall. Based on our study findings, we suggest a novel workflow to guide the use of these clinical measures for ED patients with falls.
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2250801-6
    ISSN 2152-0895 ; 1539-8412
    ISSN (online) 2152-0895
    ISSN 1539-8412
    DOI 10.1519/JPT.0000000000000403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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