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  1. Article ; Online: Cancer and the Metaorganism.

    Zitvogel, Laurence / Kroemer, Guido

    Cancer discovery

    2024  Volume 14, Issue 4, Page(s) 658–662

    Abstract: Summary: Pathogenic shifts in the gut microbiota are part of the "ecological" alterations that accompany tumor progression and compromise immunosurveillance. The future management of health and disease including cancer will rely on the diagnosis of such ...

    Abstract Summary: Pathogenic shifts in the gut microbiota are part of the "ecological" alterations that accompany tumor progression and compromise immunosurveillance. The future management of health and disease including cancer will rely on the diagnosis of such shifts and their therapeutic correction by general or personalized strategies, hence restoring metaorganismal homeostasis.
    MeSH term(s) Humans ; Neoplasms ; Gastrointestinal Microbiome ; Homeostasis
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2625242-9
    ISSN 2159-8290 ; 2159-8274
    ISSN (online) 2159-8290
    ISSN 2159-8274
    DOI 10.1158/2159-8290.CD-23-1484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6916: Show issues Location:
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  2. Article ; Online: Introduction to the Special Issue: Nutrition, microbiota and immunity.

    Zitvogel, Laurence / Kroemer, Guido

    Seminars in immunology

    2023  Volume 67, Page(s) 101767

    MeSH term(s) Humans ; Microbiota ; Gastrointestinal Microbiome
    Language English
    Publishing date 2023-05-02
    Publishing country England
    Document type Editorial
    ZDB-ID 1018141-6
    ISSN 1096-3618 ; 1044-5323
    ISSN (online) 1096-3618
    ISSN 1044-5323
    DOI 10.1016/j.smim.2023.101767
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    Zs.A 2843: Show issues Location:
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  3. Article ; Online: Anticancer action of caloric restrictions via microbiota.

    Zitvogel, Laurence / Kroemer, Guido

    Nature metabolism

    2023  Volume 5, Issue 1, Page(s) 8–9

    MeSH term(s) Microbiota ; Gastrointestinal Microbiome
    Language English
    Publishing date 2023-01-31
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ISSN 2522-5812
    ISSN (online) 2522-5812
    DOI 10.1038/s42255-022-00705-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Light shed from the gut in large B-cell lymphoma.

    Bigenwald, Camille / Zitvogel, Laurence

    Blood

    2023  Volume 141, Issue 18, Page(s) 2165–2166

    MeSH term(s) Humans ; Dysbiosis ; Lymphoma, Large B-Cell, Diffuse/pathology
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023019858
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    Zs.MO 364: Show issues

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  5. Article ; Online: Dietary fibers affecting gastrointestinal immunity.

    Zitvogel, Laurence / Kroemer, Guido

    Trends in immunology

    2023  Volume 44, Issue 11, Page(s) 868–870

    Abstract: Dietary fibers, including chitin, have a major impact on gastrointestinal (GI) physiology and immunity. Two recent articles, by Parrish et al. and Kim et al., credit depletion of dietary fibers or supplementation with chitin, with negative and positive ... ...

    Abstract Dietary fibers, including chitin, have a major impact on gastrointestinal (GI) physiology and immunity. Two recent articles, by Parrish et al. and Kim et al., credit depletion of dietary fibers or supplementation with chitin, with negative and positive effects, respectively, on the immune system of the murine digestive tract. This has relevant implications for food allergies and systemic metabolism.
    MeSH term(s) Humans ; Animals ; Mice ; Verrucomicrobia/metabolism ; Dietary Fiber ; Gastrointestinal Tract ; Chitin/metabolism
    Chemical Substances Dietary Fiber ; Chitin (1398-61-4)
    Language English
    Publishing date 2023-10-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2036831-8
    ISSN 1471-4981 ; 1471-4906
    ISSN (online) 1471-4981
    ISSN 1471-4906
    DOI 10.1016/j.it.2023.09.008
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    Zs.A 1601: Show issues Location:
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    Zs.MG 2: Show issues

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  6. Article ; Online: Boosting the immunotherapy response by nutritional interventions.

    Zitvogel, Laurence / Kroemer, Guido

    The Journal of clinical investigation

    2022  Volume 132, Issue 11

    MeSH term(s) Immunologic Factors ; Immunotherapy
    Chemical Substances Immunologic Factors
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI161483
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  7. Article ; Online: A probiotic supplement boosts response to cancer immunotherapy.

    Derosa, Lisa / Zitvogel, Laurence

    Nature medicine

    2022  Volume 28, Issue 4, Page(s) 633–634

    MeSH term(s) Dietary Supplements ; Humans ; Immunotherapy ; Neoplasms/therapy ; Probiotics/therapeutic use
    Language English
    Publishing date 2022-03-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-022-01723-4
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    Zs.A 4212: Show issues Location:
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    Zs.MG 39: Show issues

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  8. Article ; Online: Tumor-infiltrating lymphocytes for melanoma immunotherapy.

    Kepp, Oliver / Liu, Peng / Zitvogel, Laurence / Kroemer, Guido

    Oncoimmunology

    2023  Volume 12, Issue 1, Page(s) 2175506

    MeSH term(s) Humans ; Lymphocytes, Tumor-Infiltrating ; Melanoma/therapy ; Immunotherapy
    Language English
    Publishing date 2023-02-07
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2645309-5
    ISSN 2162-402X ; 2162-402X
    ISSN (online) 2162-402X
    ISSN 2162-402X
    DOI 10.1080/2162402X.2023.2175506
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  9. Article ; Online: Ghrelin and leptin regulating wound healing.

    Kroemer, Guido / Zitvogel, Laurence

    Trends in immunology

    2022  Volume 43, Issue 10, Page(s) 777–779

    Abstract: A recent article by Kratofil et al. investigated the immune inflammatory response against Staphylococcus aureus-contaminated foreign bodies placed under mouse skin. In this model, neutrophils are indispensable for bacterial clearance, while monocyte- ... ...

    Abstract A recent article by Kratofil et al. investigated the immune inflammatory response against Staphylococcus aureus-contaminated foreign bodies placed under mouse skin. In this model, neutrophils are indispensable for bacterial clearance, while monocyte-derived macrophages are required for optimal wound healing. Intriguingly, ghrelin produced by macrophages favors, and leptin produced by hypodermal adipocytes inhibits, an adequate foreign body response.
    MeSH term(s) Animals ; Ghrelin ; Leptin ; Mice ; Neutrophils ; Staphylococcal Infections ; Wound Healing
    Chemical Substances Ghrelin ; Leptin
    Language English
    Publishing date 2022-08-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2036831-8
    ISSN 1471-4981 ; 1471-4906
    ISSN (online) 1471-4981
    ISSN 1471-4906
    DOI 10.1016/j.it.2022.08.005
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  10. Article ; Online: Cross-reactivity between microbial and tumor antigens.

    Zitvogel, Laurence / Kroemer, Guido

    Current opinion in immunology

    2022  Volume 75, Page(s) 102171

    Abstract: The composition of the gut microbiota has a major impact on anticancer immunosurveillance. This effect is in part determined by systemic effects of bacterial or fungal metabolites, as well as by microbial ligands of pattern recognition receptors that ... ...

    Abstract The composition of the gut microbiota has a major impact on anticancer immunosurveillance. This effect is in part determined by systemic effects of bacterial or fungal metabolites, as well as by microbial ligands of pattern recognition receptors that modulate adjuvant signals and hence determine the general immune tonus. In addition, microbial antigens can elicit specific T lymphocyte responses that are cross-reactive with respect to tumor-associated antigens, hence inducing specific antitumor immune responses. Here, we discuss current evidence in favor of such cross-reactive anticancer/antimicrobial T cell response and delineate a methodology to demonstrate their actual importance for the immune control of malignant cells.
    MeSH term(s) Antigens, Neoplasm/metabolism ; Bacteria ; Gastrointestinal Microbiome ; Humans ; Immunotherapy ; T-Lymphocytes
    Chemical Substances Antigens, Neoplasm
    Language English
    Publishing date 2022-02-24
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1035767-1
    ISSN 1879-0372 ; 0952-7915
    ISSN (online) 1879-0372
    ISSN 0952-7915
    DOI 10.1016/j.coi.2022.102171
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