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  1. Article ; Online: Origin of Interface Limitation in Zn(O,S)/CuInS

    Sood, Mohit / Bombsch, Jakob / Lomuscio, Alberto / Shukla, Sudhanshu / Hartmann, Claudia / Frisch, Johannes / Bremsteller, Wolfgang / Ueda, Shigenori / Wilks, Regan G / Bär, Marcus / Siebentritt, Susanne

    ACS applied materials & interfaces

    2022  Volume 14, Issue 7, Page(s) 9676–9684

    Abstract: Copper indium disulfide ( ... ...

    Abstract Copper indium disulfide (CuInS
    Language English
    Publishing date 2022-02-08
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.1c19156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Online Emotions During the Storming of the U.S. Capitol

    Jakubik, Johannes / Vössing, Michael / Bär, Dominik / Pröllochs, Nicolas / Feuerriegel, Stefan

    Evidence from the Social Media Network Parler

    2022  

    Abstract: The storming of the U.S. Capitol on January 6, 2021 has led to the killing of 5 people and is ...

    Abstract The storming of the U.S. Capitol on January 6, 2021 has led to the killing of 5 people and is widely regarded as an attack on democracy. The storming was largely coordinated through social media networks such as Parler. Yet little is known regarding how users interacted on Parler during the storming of the Capitol. In this work, we examine the emotion dynamics on Parler during the storming with regard to heterogeneity across time and users. For this, we segment the user base into different groups (e.g., Trump supporters and QAnon supporters). We use affective computing (Kratzwald et al. 2018) to infer the emotions in the contents, thereby allowing us to provide a comprehensive assessment of online emotions. Our evaluation is based on a large-scale dataset from Parler, comprising of 717,300 posts from 144,003 users. We find that the user base responded to the storming of the Capitol with an overall negative sentiment. Akin to this, Trump supporters also expressed a negative sentiment and high levels of unbelief. In contrast to that, QAnon supporters did not express a more negative sentiment during the storming. We further provide a cross-platform analysis and compare the emotion dynamics on Parler and Twitter. Our findings point at a comparatively less negative response to the incidents on Parler compared to Twitter accompanied by higher levels of disapproval and outrage. Our contribution to research is three-fold: (1) We identify online emotions that were characteristic of the storming; (2) we assess emotion dynamics across different user groups on Parler; (3) we compare the emotion dynamics on Parler and Twitter. Thereby, our work offers important implications for actively managing online emotions to prevent similar incidents in the future.

    Comment: Accepted at the International AAAI Conference on Web and Social Media (ICWSM, 2023)
    Keywords Computer Science - Social and Information Networks
    Publishing date 2022-04-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: S erratus anterior plane block alone, paravertebral block alone and their combination in video-assisted thoracoscopic surgery: the THORACOSOPIC double-blind, randomized trial.

    Leviel, Florent / Fourdrain, Alex / Delatre, Florian / De Dominicis, Florence / Lefebvre, Thomas / Bar, Stéphane / Alshatri, Hamza Yahia / Lorne, Emmanuel / Georges, Olivier / Berna, Pascal / Dupont, Hervé / Meynier, Jonathan / Abou-Arab, Osama

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2024  Volume 65, Issue 4

    Abstract: Objectives: Serratus anterior plane block (SAPB) and paravertebral block (PVB) are well known to reduce pain levels after video-assisted thoracoscopic surgery (VATS). However, the relative efficacies of each block and a combination of the 2 have not ... ...

    Abstract Objectives: Serratus anterior plane block (SAPB) and paravertebral block (PVB) are well known to reduce pain levels after video-assisted thoracoscopic surgery (VATS). However, the relative efficacies of each block and a combination of the 2 have not been fully characterized. The objective of the present study was to assess the efficacy of PVB alone, SAPB alone and the combination of PVB and SAPB with regard to the occurrence and intensity of pain after VATS.
    Methods: We conducted the THORACOSOPIC single-centre, double-blind, randomized trial in adult patients due to undergo elective VATS lung resection. The participants were randomized to PVB only, SAPB only and PVB + SAPB groups. The primary end-point was pain on coughing on admission to the postanaesthesia care unit. The secondary end-points were postoperative pain at rest and on coughing at other time points and the cumulative opioid consumption. Pain was scored on a visual analogue scale.
    Results: One-hundred and fifty-six patients (52 in each group) were included. On admission to the postanaesthesia care unit, the 3 groups did not differ significantly with regard to the pain on coughing: the visual analogue scale score was 3 (0-6), 4 (0-8) and 2 (0-6) in the PVB, SAPB and PVB + SAPB groups, respectively (P = 0.204). During postoperative care, the overall pain score was significantly lower in the SABP + PVP group at rest and on cough.
    Conclusions: The combination of SABP + PVB could be beneficial for pain management in VATS in comparison to SABP or PVB alone.
    MeSH term(s) Adult ; Humans ; Thoracic Surgery, Video-Assisted/adverse effects ; Nerve Block ; Analgesics, Opioid ; Pain, Postoperative/prevention & control
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2024-03-28
    Publishing country Germany
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezae082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Normal cell cycle progression requires negative regulation of E2F1 by Groucho during S phase and its relief at G2 phase.

    Bar-Cohen, Shaked / Martínez Quiles, María Lorena / Baskin, Alexey / Dawud, Ruba / Jennings, Barbara H / Paroush, Ze'ev

    Development (Cambridge, England)

    2023  Volume 150, Issue 11

    Abstract: ... expressed throughout the cell cycle, its activity is selectively inactivated by phosphorylation, except in S ...

    Abstract The cell cycle depends on a sequence of steps that are triggered and terminated via the synthesis and degradation of phase-specific transcripts and proteins. Although much is known about how stage-specific transcription is activated, less is understood about how inappropriate gene expression is suppressed. Here, we demonstrate that Groucho, the Drosophila orthologue of TLE1 and other related human transcriptional corepressors, regulates normal cell cycle progression in vivo. We show that, although Groucho is expressed throughout the cell cycle, its activity is selectively inactivated by phosphorylation, except in S phase when it negatively regulates E2F1. Constitutive Groucho activity, as well as its depletion and the consequent derepression of e2f1, cause cell cycle phenotypes. Our results suggest that Cdk1 contributes to phase-specific phosphorylation of Groucho in vivo. We propose that Groucho and its orthologues play a role in the metazoan cell cycle that may explain the links between TLE corepressors and several types of human cancer.
    MeSH term(s) Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Cycle/genetics ; Co-Repressor Proteins/genetics ; Co-Repressor Proteins/metabolism ; Drosophila/metabolism ; E2F1 Transcription Factor/genetics ; E2F1 Transcription Factor/metabolism ; G2 Phase ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; S Phase ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism
    Chemical Substances Basic Helix-Loop-Helix Transcription Factors ; Co-Repressor Proteins ; E2F1 Transcription Factor ; Repressor Proteins ; E2f1 protein, Drosophila ; gro protein, Drosophila ; Drosophila Proteins
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 90607-4
    ISSN 1477-9129 ; 0950-1991
    ISSN (online) 1477-9129
    ISSN 0950-1991
    DOI 10.1242/dev.201041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Properties of pellets of torrefied U.S. waste blends.

    Zinchik, Stas / Xu, Zhuo / Kolapkar, Shreyas S / Bar-Ziv, Ezra / McDonald, Armando G

    Waste management (New York, N.Y.)

    2020  Volume 104, Page(s) 130–138

    Abstract: With the continued growing U.S. population, solid waste generation will increase, which will lead ...

    Abstract With the continued growing U.S. population, solid waste generation will increase, which will lead to undesired and significant growth in landfilling. Thermal treatment can turn these high calorific value wastes into fuels that can be used in small-to-large power plants. This article focuses on using blends with 40% plastic and 60% fiber wastes and converting them into densified solid fuel by torrefaction and extrusion. The material was torrefied at 300 °C to obtain torrefied samples with different mass losses, ranging from 0% to a maximum of 51%. The torrefaction results showed a clear synergy between plastics and fibers. The torrefied material was then extruded into 9 mm diameter rods and the products were characterized by molecular functional group analysis, thermomechanical analysis, dynamic mechanical analysis, dynamic rheological measurement, density measurement, flexural testing, water absorption test, size distribution measurement, heat content test, and combustion test. The fiber content in the material decreased as mass loss increased, and the process reduced significantly the variability of the material. The heat content increased as the mass loss increased. The plastic in the feedstock acted as a process enabler as it imparted properties like bindability, water resistance, high heat content, and increased degradation reaction rate.
    MeSH term(s) Biomass ; Hot Temperature ; Plastics ; Solid Waste ; Temperature ; Water
    Chemical Substances Plastics ; Solid Waste ; Water (059QF0KO0R)
    Language English
    Publishing date 2020-01-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2001471-5
    ISSN 1879-2456 ; 0956-053X
    ISSN (online) 1879-2456
    ISSN 0956-053X
    DOI 10.1016/j.wasman.2020.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cost-effectiveness and public health impact of RTS,S/AS01

    Ndeketa, Latif / Mategula, Donnie / Terlouw, Dianne J / Bar-Zeev, Naor / Sauboin, Christophe J / Biernaux, Sophie

    Wellcome open research

    2021  Volume 5, Page(s) 260

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-08-12
    Publishing country England
    Document type Journal Article
    ISSN 2398-502X
    ISSN 2398-502X
    DOI 10.12688/wellcomeopenres.16224.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The State of the World’s Midwifery 2021 report

    Andrea Nove / Petra ten Hoope-Bender / Martin Boyce / Sarah Bar-Zeev / Luc de Bernis / Geeta Lal / Zoë Matthews / Million Mekuria / Caroline S. E. Homer

    Human Resources for Health, Vol 19, Iss 1, Pp 1-

    findings to drive global policy and practice

    2021  Volume 7

    Abstract: Abstract The third global State of the World’s Midwifery report (SoWMy 2021) provides an updated ...

    Abstract Abstract The third global State of the World’s Midwifery report (SoWMy 2021) provides an updated evidence base on the sexual, reproductive, maternal, newborn and adolescent health (SRMNAH) workforce. For the first time, SoWMy includes high-income countries (HICs) as well as low- and middle-income countries. This paper describes the similarities and differences between regions and income groups, and discusses the policy implications of these variations. SoWMy 2021 estimates a global shortage of 900,000 midwives, which is particularly acute in low-income countries (LICs) and in Africa. The shortage is projected to improve only slightly by 2030 unless additional investments are made. The evidence suggests that these investments would yield important returns, including: more positive birth experiences, improved health outcomes, and inclusive and equitable economic growth. Most HICs have sufficient SRMNAH workers to meet the need for essential interventions, and their education and regulatory environments tend to be strong. Upper-middle-income countries also tend to have strong policy environments. LICs and lower-middle-income countries tend to have a broader scope of practice for midwives, and many also have midwives in leadership positions within national government. Key regional variations include: major midwife shortages in Africa and South-East Asia but more promising signs of growth in South-East Asia than in Africa; a strong focus in Africa on professional midwives (rather than associate professionals: the norm in many South-East Asian countries); heavy reliance on medical doctors rather than midwives in the Americas and Eastern Mediterranean regions and parts of the Western Pacific; and a strong educational and regulatory environment in Europe but a lack of midwife leaders at national level. SoWMy 2021 provides stakeholders with the latest data and information to inform their efforts to build back better and fairer after COVID-19. This paper provides a number of policy responses to SoWMy 2021 that are ...
    Keywords Midwives ; Midwifery ; Human resources for health ; Health workforce ; Sexual ; reproductive ; maternal ; newborn and adolescent health ; Medicine (General) ; R5-920 ; Public aspects of medicine ; RA1-1270
    Subject code 306 ; 360
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Properties of pellets of torrefied U.S. waste blends

    Zinchik, Stas / Xu, Zhuo / Kolapkar, Shreyas S / Bar-Ziv, Ezra / McDonald, Armando G

    Waste management. 2020 Mar. 01, v. 104

    2020  

    Abstract: With the continued growing U.S. population, solid waste generation will increase, which will lead ...

    Abstract With the continued growing U.S. population, solid waste generation will increase, which will lead to undesired and significant growth in landfilling. Thermal treatment can turn these high calorific value wastes into fuels that can be used in small-to-large power plants. This article focuses on using blends with 40% plastic and 60% fiber wastes and converting them into densified solid fuel by torrefaction and extrusion. The material was torrefied at 300 °C to obtain torrefied samples with different mass losses, ranging from 0% to a maximum of 51%. The torrefaction results showed a clear synergy between plastics and fibers. The torrefied material was then extruded into 9 mm diameter rods and the products were characterized by molecular functional group analysis, thermomechanical analysis, dynamic mechanical analysis, dynamic rheological measurement, density measurement, flexural testing, water absorption test, size distribution measurement, heat content test, and combustion test. The fiber content in the material decreased as mass loss increased, and the process reduced significantly the variability of the material. The heat content increased as the mass loss increased. The plastic in the feedstock acted as a process enabler as it imparted properties like bindability, water resistance, high heat content, and increased degradation reaction rate.
    Keywords combustion ; extrusion ; feedstocks ; fiber content ; fuels ; heat ; moieties ; pellets ; plastics ; power plants ; solid wastes ; torrefaction ; waste management ; water uptake ; United States
    Language English
    Dates of publication 2020-0301
    Size p. 130-138.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2001471-5
    ISSN 1879-2456 ; 0956-053X
    ISSN (online) 1879-2456
    ISSN 0956-053X
    DOI 10.1016/j.wasman.2020.01.009
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Preliminary nonclinical safety and immunogenicity of an rVSV-ΔG-SARS-CoV-2-S vaccine in mice, hamsters, rabbits and pigs.

    Madar-Balakirski, Noa / Rosner, Amir / Melamed, Sharon / Politi, Boaz / Steiner, Michal / Tamir, Hadas / Yahalom-Ronen, Yfat / Bar-David, Elad / Ben-Shmuel, Amir / Sittner, Assa / Glinert, Itai / Weiss, Shay / Bar-Haim, Erez / Cohen, Hila / Elia, Uri / Achdout, Hagit / Erez, Noam / Rotem, Shahar / Lazar, Shlomi /
    Nyska, Abraham / Yitzhaki, Shmuel / Beth-Din, Adi / Levy, Haim / Paran, Nir / Israely, Tomer / Marcus, Hadar

    Archives of toxicology

    2022  Volume 96, Issue 3, Page(s) 859–875

    Abstract: rVSV-ΔG-SARS-CoV-2-S is a clinical stage (Phase 2) replication competent recombinant vaccine ...

    Abstract rVSV-ΔG-SARS-CoV-2-S is a clinical stage (Phase 2) replication competent recombinant vaccine against SARS-CoV-2. To evaluate the safety profile of the vaccine, a series of non-clinical safety, immunogenicity and efficacy studies were conducted in four animal species, using multiple doses (up to 10
    MeSH term(s) Animals ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; COVID-19 Vaccines/immunology ; COVID-19 Vaccines/toxicity ; Cricetinae ; Female ; Membrane Glycoproteins/genetics ; Mesocricetus ; Mice ; Mice, Inbred C57BL ; Rabbits ; Swine ; Vaccination ; Vaccines, Synthetic/toxicity ; Viral Envelope Proteins/genetics
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral ; COVID-19 Vaccines ; G protein, vesicular stomatitis virus ; Membrane Glycoproteins ; Vaccines, Synthetic ; Viral Envelope Proteins
    Language English
    Publishing date 2022-01-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124992-7
    ISSN 1432-0738 ; 0340-5761
    ISSN (online) 1432-0738
    ISSN 0340-5761
    DOI 10.1007/s00204-021-03214-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Therapeutic effects of different doses of prebiotic (isolated from S

    de Sales Guilarducci, Janina / Marcelino, Breno Augusto Ribeiro / Konig, Isaac Filipe Moreira / Orlando, Tamira Maria / Varaschin, Mary Suzan / Pereira, Luciano José

    Diabetology & metabolic syndrome

    2020  Volume 12, Page(s) 69

    Abstract: Background: The regular intake of fiber generates numerous health benefits. However, the efficacy depends on the duration of consumption and the ingested dose. Studies investigating the optimal dose are of interest to enable the inclusion of fiber in ... ...

    Abstract Background: The regular intake of fiber generates numerous health benefits. However, the efficacy depends on the duration of consumption and the ingested dose. Studies investigating the optimal dose are of interest to enable the inclusion of fiber in the routine treatment of diabetic patients.
    Objective: We aimed to evaluate the effects of different doses of β-glucan (BG-isolated from
    Methods: Forty animals were randomly divided into six groups receiving 0 mg/kg, 10 mg/kg, 20 mg/kg, or 40 mg/kg BG daily for 4 weeks or fish oil derivative [1000 mg/kg of omega-3 fatty acids (n-3)] for the same period. One additional group was composed of healthy controls. Serum metabolic and immunological parameters were evaluated by colorimetric and ELISA assays respectively. Histopathological analysis of the liver, small intestine and pancreas were also conducted. Significant changes due to BG intake were set into regression models with second-degree fit in order to estimate the optimal BG dose to achieve health benefits.
    Results: The animals that ingested BG had lower food and water intake (p < 0.05) than the negative control group (0 mg/kg). However, consumption was still elevated in comparison to healthy controls. Blood glucose and serum levels of total cholesterol, LDL-c, and TG (p < 0.05) reduced in comparison to diabetic animals without treatment (better or similar to n-3 group depending on dose), but did not reach normal levels (in comparison to healthy controls). HDL-c was not different (p > 0.05) among all groups. These reductions were already seen with the lowest dose of 10 mg/kg. On average, the serum levels of the hepatic enzymes ALT and AST were 40% and 60% lower in the BG groups in comparison to diabetic animals without treatment (better results than n-3 group). The group receiving 40 mg/kg reached similar values of healthy controls for ALT; whereas the same result occurred from the dose of 10 mg/kg for AST. The ideal dose, estimated from the mean of all metabolic parameters was approximately 30 mg/kg/day. Regarding the immunological profile, TNF-α significantly decreased in the BG groups compared to controls (p < 0.05), reaching better values than n-3 group and similar to healthy controls. No significant differences were found between the groups in IL-1β or IL-10 (p > 0.05). No histological changes were found in the pancreas, liver, or intestine due to treatment among diabetic animals.
    Conclusions: BG significantly reduced blood glucose as well as serum total cholesterol, LDL-c and TG. There was a hepatoprotective effect due to the reduction in ALT and AST and a reduction in TNF-α, indicating a modulation of the immune response. In general, BG effects were better than n-3 supplement (or at least comparable) depending on the dose.
    Language English
    Publishing date 2020-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2518786-7
    ISSN 1758-5996
    ISSN 1758-5996
    DOI 10.1186/s13098-020-00576-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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