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  1. Book: Neural plasticity and cognitive development

    Stiles, Joan

    insights from children with perinatal brain injury

    2012  

    Author's details Joan Stiles
    Keywords Brain Injuries / complications ; Infant, Newborn ; Developmental Disabilities / etiology ; Brain / growth & development ; Neuronal Plasticity / physiology ; Child Development ; Child ; Infant
    Language English
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index ; Neuroplasticity and the developing brain -- The basics of brain development -- Etiology and neurological effects of perinatal stroke -- Somatosensory and motor processes -- Visuospatial processes -- Attention, memory, and executive functions -- Early communicative development to first words -- Later language development : syntax and discourse -- Plasticity of overall intellectual functioning : evidence from standardized tests -- Clinical implications -- Toward and integrative model of neurobehavioral development
    HBZ-ID HT017282937
    ISBN 978-0-19-538994-4 ; 0-19-538994-8
    Database Catalogue ZB MED Medicine, Health

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  2. Book: The fundamentals of brain development

    Stiles, Joan

    integrating nature and nurture

    2008  

    Author's details Joan Stiles
    Keywords Brain / embryology ; Brain / growth & development ; Neurons / physiology ; Mental Disorders / etiology ; Neuropsychology ; Brain/Growth ; Nature and nurture
    Subject code 612.82
    Language English
    Size XII, 421 S. : Ill.
    Publisher Harvard Univ. Press
    Publishing place Cambridge, Mass. u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015603039
    ISBN 978-0-674-02674-2 ; 0-674-02674-8
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Principles of brain development.

    Stiles, Joan

    Wiley interdisciplinary reviews. Cognitive science

    2017  Volume 8, Issue 1-2

    Abstract: Throughout much of the 20th century, the major models of brain development were strongly deterministic. It was thought that brain development proceeds via a prescribed blueprint that is somehow innately specified in the organism. Contemporary models ... ...

    Abstract Throughout much of the 20th century, the major models of brain development were strongly deterministic. It was thought that brain development proceeds via a prescribed blueprint that is somehow innately specified in the organism. Contemporary models present a distinctly different view of both inheritance and brain development. First, we do not inherit blueprints or plans, we inherit genes and the cellular machinery for expressing them. Genes carry essential information for creating proteins, but do not determine biological processes or developmental outcomes; the first cells contain the elements necessary for creating proteins based on the information coded in the nucleotide sequences of genes. Second, brain development is dynamic: the biological state of the brain at any moment is the product of developmental processes that involve an intricate interplay among genes and an ever-expanding range of environmental factors-from local cellular events to influences from the outside world. In science, models matter. They reflect underlying assumptions about how things can happen, and thus influence the kinds of questions we ask, the kinds of experiments we propose, the therapies we develop, and the educational curricula we construct. The dynamic model of brain development accounts for powerful neurobehavioral effects that can simply not be accommodated by deterministic models. WIREs Cogn Sci 2017, 8:e1402. doi: 10.1002/wcs.1402 For further resources related to this article, please visit the WIREs website.
    MeSH term(s) Animals ; Brain/growth & development ; Gene-Environment Interaction ; Human Development ; Humans ; Neuronal Plasticity
    Language English
    Publishing date 2017-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2553336-8
    ISSN 1939-5086 ; 1939-5078
    ISSN (online) 1939-5086
    ISSN 1939-5078
    DOI 10.1002/wcs.1402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The effects of injury to dynamic neural networks in the mature and developing brain.

    Stiles, Joan

    Developmental psychobiology

    2012  Volume 54, Issue 3, Page(s) 343–349

    Abstract: This special section emphasizes three key factors relevant to understanding brain responses to injury. First, it is important to consider the impact of injury on brain networks rather then just the localized neuropathology. In contrast to older ... ...

    Abstract This special section emphasizes three key factors relevant to understanding brain responses to injury. First, it is important to consider the impact of injury on brain networks rather then just the localized neuropathology. In contrast to older localizationist models, neural systems views emphasize that the effects of localized injury cascade through the neural system altering function at multiple levels. Thus, effective remediation must accommodate the multiple effects of brain injury. Second, the role of neural plasticity in the brain response to injury is critical. Rehabilitation implies that neural system is adaptive and capable of changing in response to input. Thus exploiting the brain's inherent plasticity is central to remediation. Finally, the timing of injury is an essential consideration. Adult injury disrupts stable neural systems and plasticity operates to regain functional balance. In contrast, early injury affects fundamental development processes and alters the emerging organization and functioning of neural systems.
    MeSH term(s) Animals ; Brain/physiopathology ; Brain Injuries/physiopathology ; Humans ; Nerve Net/physiopathology ; Neuronal Plasticity/physiology ; Recovery of Function/physiology
    Language English
    Publishing date 2012-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 4107-5
    ISSN 1098-2302 ; 0012-1630
    ISSN (online) 1098-2302
    ISSN 0012-1630
    DOI 10.1002/dev.20628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Brain development and the nature versus nurture debate.

    Stiles, Joan

    Progress in brain research

    2011  Volume 189, Page(s) 3–22

    Abstract: Over the past three decades, developmental neurobiologists have made tremendous progress in defining basic principles of brain development. This work has changed the way we think about how brains develop. Thirty years ago, the dominant model was strongly ...

    Abstract Over the past three decades, developmental neurobiologists have made tremendous progress in defining basic principles of brain development. This work has changed the way we think about how brains develop. Thirty years ago, the dominant model was strongly deterministic. The relationship between brain and behavioral development was viewed as unidirectional; that is, brain maturation enables behavioral development. The advent of modern neurobiological methods has provided overwhelming evidence that it is the interaction of genetic factors and the experience of the individual that guides and supports brain development. Brains do not develop normally in the absence of critical genetic signaling, and they do not develop normally in the absence of essential environmental input. The fundamental facts about brain development should be of critical importance to neuropsychologists trying to understand the relationship between brain and behavioral development. However, the underlying assumptions of most contemporary psychological models reflect largely outdated ideas about how the biological system develops and what it means for something to be innate. Thus, contemporary models of brain development challenge the foundational constructs of the nature versus nurture formulation in psychology. The key to understanding the origins and emergence of both the brain and behavior lies in understanding how inherited and environmental factors are engaged in the dynamic and interactive processes that define and guide development of the neurobehavioral system.
    MeSH term(s) Behavior/physiology ; Body Patterning ; Brain/embryology ; Brain/growth & development ; Brain/physiology ; Environment ; Humans ; Inheritance Patterns ; Nature ; Neural Stem Cells/physiology ; Neuronal Plasticity ; Signal Transduction
    Language English
    Publishing date 2011
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ISSN 1875-7855 ; 0079-6123
    ISSN (online) 1875-7855
    ISSN 0079-6123
    DOI 10.1016/B978-0-444-53884-0.00015-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Construction of the human forebrain.

    Jernigan, Terry L / Stiles, Joan

    Wiley interdisciplinary reviews. Cognitive science

    2017  Volume 8, Issue 1-2

    Abstract: The adult human brain is arguably the most complex of biological systems. It contains 86 billion neurons (the information processing cells of the brain) and many more support cells. The neurons, with the assistance of the support cells, form trillions of ...

    Abstract The adult human brain is arguably the most complex of biological systems. It contains 86 billion neurons (the information processing cells of the brain) and many more support cells. The neurons, with the assistance of the support cells, form trillions of connections creating complex, interconnected neural networks that support all human thought, feeling, and action. A challenge for modern neuroscience is to provide a model that accounts for this exquisitely complex and dynamic system. One fundamental part of this model is an account of how the human brain develops. This essay describes two important aspects of this developmental story. The first part of the story focuses on the remarkable and dynamic set of events that unfold during the prenatal period to give rise to cell lineage that form the essential substance of the brain, particularly the structures of the cerebral hemispheres. The second part of the story focuses on the formation of the major brain pathways of the cerebrum, the intricate fiber bundles that connect different populations of neurons to form the information processing systems that support all human thought and action. These two aspects of early brain development provide an essential foundation for understanding how the structure, organization, and functioning of the human brain emerge. WIREs Cogn Sci 2017, 8:e1409. doi: 10.1002/wcs.1409 For further resources related to this article, please visit the WIREs website.
    MeSH term(s) Humans ; Neural Pathways/anatomy & histology ; Neural Pathways/embryology ; Neural Pathways/growth & development ; Neural Stem Cells ; Neuroglia/physiology ; Neurons/physiology ; Prosencephalon/anatomy & histology ; Prosencephalon/embryology ; Prosencephalon/growth & development
    Language English
    Publishing date 2017-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2553336-8
    ISSN 1939-5086 ; 1939-5078
    ISSN (online) 1939-5086
    ISSN 1939-5078
    DOI 10.1002/wcs.1409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Conference proceedings: Spatial cognition

    Stiles-Davis, Joan

    brain bases and development ; [based on the Spatial Cognition Workshop, held Apr. 1984 at the Salk Institute for Biological Studies]

    1988  

    Event/congress Spatial Cognition Workshop (1984, SanDiegoCalif.)
    Author's details ed. by Joan Stiles-Davis
    Keywords Space Perception / congresses ; Neuropsychology / congresses ; Raumwahrnehmung ; Physiologie ; Neuropsychologie
    Subject Humanphysiologie ; Mensch ; Körperfunktion ; Wahrnehmung ; Raumerleben ; Raumerlebnis ; Räumliche Wahrnehmung ; Raumempfindung
    Size XV, 459 S. : graph. Darst.
    Publisher Erlbaum
    Publishing place Hillsdale, NJ u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT003401586
    ISBN 0-8058-0046-8 ; 0-8058-0078-6 ; 978-0-8058-0046-3 ; 978-0-8058-0078-4
    Database Catalogue ZB MED Medicine, Health

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  8. Book: Neural plasticity and cognitive development

    Stiles, Joan

    insights from children with perinatal brain injury

    2012  

    Author's details Joan Stiles ... [et al.]
    MeSH term(s) Brain Injuries/complications ; Infant, Newborn ; Developmental Disabilities/etiology ; Brain/growth & development ; Neuronal Plasticity/physiology ; Child Development ; Child ; Infant
    Language English
    Size xi, 366 p. :, ill.
    Publisher Oxford University Press
    Publishing place New York
    Document type Book
    ISBN 9780195389944 ; 0195389948
    Database Catalogue of the US National Library of Medicine (NLM)

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  9. Article ; Online: Implementation Costs of Technology-Enhanced Transitional Palliative Care for Rural Caregivers.

    Kaufman, Brystana G / Holland, Diane E / Vanderboom, Catherine E / Ingram, Cory / Wild, Ellen M / Dose, Ann Marie / Stiles, Carole / Gustavson, Allison M / Chun, Alice / Langan, Erica M / Baer-Benson, Henry A / Mandrekar, Jay / Griffin, Joan M

    The American journal of hospice & palliative care

    2023  Volume 41, Issue 1, Page(s) 38–44

    Abstract: Objectives: Compared to urban family caregivers (FCG), rural FCG experience greater burdens accessing coordinated care for their loved ones during and after hospitalization. The impact of technology-enhanced transitional palliative care (TPC) on ... ...

    Abstract Objectives: Compared to urban family caregivers (FCG), rural FCG experience greater burdens accessing coordinated care for their loved ones during and after hospitalization. The impact of technology-enhanced transitional palliative care (TPC) on caregiver outcomes is currently being evaluated in a randomized control trial. This study evaluates resource use and health system costs of this FCG-focused TPC intervention and potential Medicare reimbursement mechanisms.
    Methods: Rural caregivers of hospitalized patients were randomized into an 8-week intervention consisting of video visits conducted by a registered nurse certified in palliative care, supplemented with phone calls and texts (n = 215), or attentional control. Labor costs were estimated for a registered nurse and compared to scenario analyses using a nurse practitioner or social worker wages. Medicare reimbursement scenarios included Transitional Care Management (TCM) and Chronic Care Management (CCM) CPT codes.
    Results: In the base case, TPC cost was $395 per FCG facilitated by a registered nurse, compared to $337 and $585 if facilitated by a social worker or nurse practitioner, respectively. Mean Medicare reimbursement in the TCM-only scenario was $322 and $260 for high or moderate complexity patients, respectively. Reimbursement in the CCM only scenario was $348 and $274 for complex and non-complex patients, respectively. Reimbursement in the TCM+CCM scenario was $496 and $397, for high/complex and moderate/non-complex patients, respectively.
    Conclusion: TPC is a feasible, low cost and sustainable strategy to enhance FCG support in rural areas. Potential reimbursement mechanisms are available to offset the costs to the health system for providing transitional palliative care to caregivers of patients recently hospitalized.
    MeSH term(s) Aged ; Humans ; United States ; Palliative Care ; Caregivers ; Transitional Care ; Medicare ; Long-Term Care
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1074344-3
    ISSN 1938-2715 ; 1049-9091
    ISSN (online) 1938-2715
    ISSN 1049-9091
    DOI 10.1177/10499091231156145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: The fundamentals of brain development

    Stiles, Joan

    integrating nature and nurture

    2008  

    Author's details Joan Stiles
    MeSH term(s) Brain/embryology ; Brain/growth & development ; Neurons/physiology ; Mental Disorders/etiology ; Neuropsychology
    Language English
    Size xii, 421 p. :, ill.
    Publisher Harvard University Press
    Publishing place Cambridge, Mass
    Document type Book
    ISBN 9780674026742 ; 0674026748
    Database Catalogue of the US National Library of Medicine (NLM)

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