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Article ; Online: Community health nurses leadership in advancing health equity.

Baxter, Catherine / Schofield, Ruth / Currie, Genevieve / Gauley, Patti

2024 Volume 41, Issue 2, Page(s) 310–317

Abstract: Objective: To describe the solutions community health nurses (CHNs) identify to address health inequities during the COVID-19 pandemic and to explore what leadership competencies enable CHNs to enact these solutions.: Design: Online survey, ... ...

Abstract	Objective: To describe the solutions community health nurses (CHNs) identify to address health inequities during the COVID-19 pandemic and to explore what leadership competencies enable CHNs to enact these solutions. Design: Online survey, distributed to all members of the Community Health Nurses of Canada and associated provincial and territorial networks. Participants: Inclusion criteria included all nurses who were working during the COVID-19 pandemic in Canada. A total of 245 responses were included in the analysis. Measurement: The survey included 25 open ended and fixed response questions. Descriptive statistics were used to describe the quantitative data. Framework Analysis was used to analyze the qualitative data. Results: Solutions focused on advancing health equity and expanding community relationships and partnerships were identified as priorities. To enact these solutions system transformation, engaging others, and developing coalitions were identified as the main leadership competencies required by CHNs. Conclusion: Participants in this study clearly articulated structural and process solutions to address health inequities among priority populations during the pandemic. CHNs described with practice knowledge and confidence that solutions enacted in system transformation with community partners are necessary to advance health equity.
MeSH term(s)	Humans ; Nurses, Community Health ; Health Equity ; Leadership ; Pandemics ; COVID-19
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	632563-4
ISSN	1525-1446 ; 0737-1209
ISSN (online)	1525-1446
ISSN	0737-1209
DOI	10.1111/phn.13286
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Zs.B 2794: Show issues

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Article ; Online: Cross-Education Effects of Isokinetic Eccentric Plantarflexor Training on Flexibility, Strength, and Muscle-Tendon Mechanics.

Kay, Anthony D / Blazevich, Anthony J / Tysoe, Jessica C / Baxter, Brett A

Medicine and science in sports and exercise

2024

Abstract: ... limbs for dorsiflexion ROM (r = 0.59) and both isometric (r = 0.79) and eccentric (r = 0.73) peak ...

Abstract	Introduction: Large increases in joint range of motion (ROM) have been reported after eccentric resistance training, however limited data exist describing the associated mechanisms or potential cross-education effects in the contralateral limb. Therefore, the effects of a 6-week isokinetic eccentric plantarflexor training program were examined in 26 participants. Methods: Before and after the training program, dorsiflexion ROM, plantarflexor strength, and muscle-tendon unit (MTU) morphology and mechanics were measured in control (n = 13) and experimental (n = 13) young adult groups. Training consisted of 5 sets of 12 maximal isokinetic eccentric plantarflexor contractions twice weekly on the right limb. Results: Significant (P < 0.05) increases in dorsiflexion ROM (4.0-9.5°), stretch tolerance (40.3-95.9%), passive elastic energy storage (47.5-161.3%), and isometric (38.1-40.6%) and eccentric (46.7-67.0%) peak plantarflexor torques were detected in both trained and contralateral limbs in the experimental group. Significant increases in gastrocnemius medialis (GM) and soleus thickness (5.4-6.1%), GM fascicle length (7.6 ± 8.5%), passive plantarflexor MTU stiffness (30.1 ± 35.5%) and Achilles tendon stiffness (5.3 ± 4.9%) were observed in the trained limb only. Significant correlations were detected between the changes in trained and contralateral limbs for dorsiflexion ROM (r = 0.59) and both isometric (r = 0.79) and eccentric (r = 0.73) peak torques. No significant changes in any metric were detected in the control group. Conclusions: Large ROM increases in the trained limb were associated with neurological, mechanical, and structural adaptations, with evidence of a cross-education effect in the contralateral limb being primarily driven by neurological adaptation (stretch tolerance). The large improvements in ROM, muscle size, and strength confirm that isokinetic eccentric training is a highly effective training tool, with potential for use in athletic and clinical populations where MTU function is impaired and current therapies are ineffective.
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	603994-7
ISSN	1530-0315 ; 0195-9131 ; 0025-7990
ISSN (online)	1530-0315
ISSN	0195-9131 ; 0025-7990
DOI	10.1249/MSS.0000000000003418
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Article ; Online: Reconstruction of Subaqueous Eruption‐Fed Current Characteristics and Source Location Using Anisotropy of Magnetic Susceptibility (AMS) at Otapahi, Dunedin Volcano, New Zealand

Baxter, R. J. M. / White, J. D. L. / Ohneiser, C. / Brenna, M.

Journal of Geophysical Research: Solid Earth. 2023 Aug., v. 128, no. 8 p.e2022JB025605-

2023

Abstract: Information about birth and early eruptions of composite volcanoes is scarce, but erosion has revealed very early deposits of the Dunedin Volcano, and we apply anisotropy of magnetic susceptibility (AMS) techniques to retrieve information about the ... ...

Abstract	Information about birth and early eruptions of composite volcanoes is scarce, but erosion has revealed very early deposits of the Dunedin Volcano, and we apply anisotropy of magnetic susceptibility (AMS) techniques to retrieve information about the earliest known, submarine, eruptive centre. Although AMS has been used to recover information from subaerial eruptions, and to examine turbidites, this is its first use in investigating depositional processes and the source location for submarine volcaniclastic deposits. AMS fabrics of the deposits, emplaced by submarine eruption‐fed density currents, show basal portions of the currents were decoupled from more‐buoyant upper parts. Triangulation of AMS vectors and orientations yields a vent site location, with some imprecision reflecting the chaotic nature of deposits rapidly aggraded within 500 m of the source vent. This method elucidates depositional processes of subaqueous volcanic currents as well as subaerial ones, while still yielding sufficient consistency for triangulation of flow source sites.
Keywords	anisotropy ; geophysics ; magnetic susceptibility ; research ; New Zealand
Language	English
Dates of publication	2023-08
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ISSN	2169-9313
DOI	10.1029/2022JB025605
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Patient and clinician priorities for information on treatment outcomes for advanced ovarian cancer: a Delphi exercise.

Baxter, Kathryn / Agnew, Heather / Morgan, Jennie / Holland, Cathrine / Flynn, Darren / Edmondson, Richard

Journal of gynecologic oncology

2024

Abstract: Objective: Patients with advanced ovarian cancer face a range of treatment options, and there is unwarranted variation in treatment decision-making between UK providers. Decision support tools that produce data on treatment outcomes as a function of ... ...

Abstract	Objective: Patients with advanced ovarian cancer face a range of treatment options, and there is unwarranted variation in treatment decision-making between UK providers. Decision support tools that produce data on treatment outcomes as a function of individual patient characteristics, would help both patients and clinicians to make informed, preference- and values-based choices. However, data on treatment outcomes to include in such tools are lacking. Methods: Following a literature review, a questionnaire was designed for use in a Delphi process to establish which treatment outcomes are important to both patients and clinicians in decision-making for treatment for advanced ovarian cancer. Patient and clinician panels were established. Results: Following 2 Delphi rounds, consensus was achieved for 7/11 items in the patient panel and 8/11 items in the clinician panel. Consensus across both panels was achieved for inclusion of both overall survival and progression free survival as important items in the decision-making process, although there remained differences of opinion as to whether these should be presented as relative or absolute values. Conclusion: Information needs for treatment decision-making in ovarian cancer differ between and within patient and clinician groups. Whilst overall survival and progression free survival are universally accepted as important data items, decision support tools will need to be nuanced to allow presentation of a range of outcomes and associated probabilities, and in a range of formats, that can be tailored to the preferences of clinician and patients.
Language	English
Publishing date	2024-03-21
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2478405-9
ISSN	2005-0399 ; 2005-0380
ISSN (online)	2005-0399
ISSN	2005-0380
DOI	10.3802/jgo.2024.35.e63
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Article ; Online: Abuse liability of two electronic nicotine delivery systems compared with combustible cigarettes and nicotine gum from an open-label randomized crossover study.

Campbell, Chris / Jin, Tao / Round, Elaine K / Nelson, Paul R / Baxter, Sarah

Scientific reports

2023 Volume 13, Issue 1, Page(s) 18951

Abstract: ... followed by the Vuse ENDS, with nicotine gum consistently having the lowest scores. The PK results (C ...

Abstract	An assessment of the likelihood of use and abuse potential for new tobacco products is an important part of tobacco product regulation in the United States and abroad. This paper reports the results of a randomized, open-label, crossover clinical study that assessed factors related to product adoption and abuse liability (AL), comparing two closed electronic nicotine delivery system (ENDS) products to combustible cigarettes and nicotine gum, high- and low-AL comparator products, respectively. During an 11-day confinement period that included multiple product familiarization sessions, healthy adult smokers participated in AL test sessions to evaluate the abuse liability of each product. During these test sessions, changes in subjective measures; speed and amount of nicotine uptake; and maximum changes in physiological effects before, during, and after use of each assigned product were assessed over 4 h. Positive subjective effects measures scores such as product-liking and overall intent to use again were highest for cigarettes, followed by the Vuse ENDS, with nicotine gum consistently having the lowest scores. The PK results (C
MeSH term(s)	Cross-Over Studies ; Electronic Nicotine Delivery Systems ; Nicotine/adverse effects ; Nicotine Chewing Gum ; Tobacco Products/adverse effects ; United States ; Humans
Chemical Substances	Nicotine (6M3C89ZY6R) ; Nicotine Chewing Gum
Language	English
Publishing date	2023-11-02
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-45894-7
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Article ; Online: The nature and causes of children's grammatical difficulties: Evidence from an intervention to improve past tense marking in children with Down syndrome.

Baxter, Rebecca / Rees, Rachel / Perovic, Alexandra / Hulme, Charles

Developmental science

2022 Volume 25, Issue 4, Page(s) e13220

Abstract: Children with language learning difficulties frequently display problems learning grammar. One such group is children with Down syndrome. This study evaluates the effectiveness of an intervention to teach the use of the regular simple past tense to ... ...

Abstract	Children with language learning difficulties frequently display problems learning grammar. One such group is children with Down syndrome. This study evaluates the effectiveness of an intervention to teach the use of the regular simple past tense to children with Down syndrome. Trained teaching assistants delivered the intervention for 20 min per day for 10 weeks. We conducted a Randomised Controlled Trial, with a waiting list control design in which the Intervention group (N = 26) received the intervention immediately, while the delayed intervention group (N = 26) received the intervention later. Immediately following the intervention, the intervention group showed significantly larger gains in the use of regular simple past tense forms (d = 1.63 on a composite measure of simple past tense formation) as well as generalisation to verbs not explicitly taught. In addition, following the intervention children made overregularisation errors by incorrectly using regular simple past tense marking for irregular verbs; such errors support the claim that children had acquired generative knowledge underlying past tense marking. The delayed intervention control group showed identical benefits from the intervention when they received it, and the gains shown by the intervention group were maintained at follow up testing. This study shows that children with Down syndrome, who display severe language difficulties, can be taught to use simple past tense marking. The theoretical and applied implications of these findings for understanding the nature, causes and treatments of children's language difficulties are discussed.
MeSH term(s)	Child ; Down Syndrome ; Humans ; Language ; Language Development Disorders ; Language Tests ; Linguistics
Language	English
Publishing date	2022-01-23
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2023952-X
ISSN	1467-7687 ; 1363-755X
ISSN (online)	1467-7687
ISSN	1363-755X
DOI	10.1111/desc.13220
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Article ; Online: Point prevalence of penicillin allergy in hospital inpatients.

Baxter, M / Bethune, C / Powell, R / Morgan, M

The Journal of hospital infection

2020 Volume 106, Issue 1, Page(s) 65–70

Abstract: Ten percent of the general population believe themselves to be allergic to beta-lactams, many erroneously. Alternative, broader-spectrum antibiotics are associated with increased drug costs and colonization with resistant organisms. A point prevalence ... ...

Abstract	Ten percent of the general population believe themselves to be allergic to beta-lactams, many erroneously. Alternative, broader-spectrum antibiotics are associated with increased drug costs and colonization with resistant organisms. A point prevalence study of hospital inpatients determined the local reported rate of penicillin allergy, the nature of allergy described, evidence of antimicrobial resistance and antimicrobial regimens used as a result. Of the 583 patients assessed, the overall rate of penicillin allergy was 13.7% [95% confidence interval (CI) 11-17%]. Rash was the most commonly reported reaction (27.5%, 95% CI 18-39%). Details of the nature of the penicillin allergy were poorly recorded on drug charts. Significantly higher rates of meticillin-resistant Staphylococcus aureus were seen in the allergic cohort (P=0.0065) compared with those without a label of penicillin allergy; this was also seen for vancomycin-resistant enterococci, but this did not reach significance. This study demonstrates an increase in detection of resistant organisms in penicillin-allergic patients which may result from use of broader-spectrum antibiotics in this group.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/adverse effects ; Cohort Studies ; Drug Hypersensitivity/epidemiology ; Female ; Hospitals ; Humans ; Inpatients ; Male ; Methicillin-Resistant Staphylococcus aureus/genetics ; Middle Aged ; Penicillins/adverse effects ; Prevalence ; Staphylococcal Infections/epidemiology ; Young Adult
Chemical Substances	Anti-Bacterial Agents ; Penicillins
Language	English
Publishing date	2020-06-15
Publishing country	England
Document type	Journal Article
ZDB-ID	779366-2
ISSN	1532-2939 ; 0195-6701
ISSN (online)	1532-2939
ISSN	0195-6701
DOI	10.1016/j.jhin.2020.06.016
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Article ; Online: NMR Fingerprints of Formyl Phloroglucinol Meroterpenoids and Their Application to the Investigation of

Baxter, James R / Holland, Darren C / Gavranich, Brody / Nicolle, Dean / Hayton, Joshua B / Avery, Vicky M / Carroll, Anthony R

Journal of natural products

2023 Volume 86, Issue 5, Page(s) 1317–1334

Abstract: NMR fingerprints provide powerful tools to identify natural products in complex mixtures. Principal component analysis and machine learning ... ...

Abstract	NMR fingerprints provide powerful tools to identify natural products in complex mixtures. Principal component analysis and machine learning using
MeSH term(s)	Eucalyptus/chemistry ; Phloroglucinol/chemistry ; Plant Leaves/chemistry ; Magnetic Resonance Spectroscopy ; Magnetic Resonance Imaging ; Molecular Structure
Chemical Substances	Phloroglucinol (DHD7FFG6YS)
Language	English
Publishing date	2023-05-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	304325-3
ISSN	1520-6025 ; 0163-3864
ISSN (online)	1520-6025
ISSN	0163-3864
DOI	10.1021/acs.jnatprod.3c00139
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Article: Inductively Coupled Plasma Mass Spectrometry: Introduction to Analytical Aspects.

Wilschefski, Scott C / Baxter, Matthew R

The Clinical biochemist. Reviews

2018 Volume 40, Issue 3, Page(s) 115–133

Abstract: Inductively coupled plasma mass spectrometry (ICP-MS) is an analytical technique that can be used to measure elements at trace levels in biological fluids. Although older techniques such as atomic absorption and atomic emission are still in use by some ... ...

Abstract	Inductively coupled plasma mass spectrometry (ICP-MS) is an analytical technique that can be used to measure elements at trace levels in biological fluids. Although older techniques such as atomic absorption and atomic emission are still in use by some laboratories, there has been a slow shift toward ICP-MS, particularly in the last decade. As this shift is likely to continue, clinical scientists should be aware of the analytical aspects of ICP-MS, as well as the potential for both spectroscopic and non-spectroscopic interference, and strategies that can be employed to eliminate or mitigate these issues.
Language	English
Publishing date	2018-03-10
Publishing country	Australia
Document type	Journal Article ; Review
ZDB-ID	1018054-0
ISSN	1838-0212 ; 0159-8090
ISSN (online)	1838-0212
ISSN	0159-8090
DOI	10.33176/AACB-19-00024
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Article ; Online: Moving towards a standardized definition of antimicrobial resistance: a comparison of the antimicrobial susceptibility profile of difficult-to-treat resistance (DTR) versus multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates (CANWARD, 2016-2021).

Walkty, A / Karlowsky, J A / Lagacé-Wiens, P R S / Baxter, M R / Adam, H J / Bay, D C / Zhanel, G G

Diagnostic microbiology and infectious disease

2023 Volume 108, Issue 2, Page(s) 116130

Abstract: Pseudomonas aeruginosa clinical isolates demonstrating difficult-to-treat resistance (DTR) and multidrug-resistant (MDR) phenotypes were evaluated by broth microdilution. Susceptibility was lower for all antimicrobials versus DTR relative to MDR isolates. ...

Abstract	Pseudomonas aeruginosa clinical isolates demonstrating difficult-to-treat resistance (DTR) and multidrug-resistant (MDR) phenotypes were evaluated by broth microdilution. Susceptibility was lower for all antimicrobials versus DTR relative to MDR isolates. Ceftazidime-avibactam, ceftolozane-tazobactam, and imipenem-relebactam susceptibility was 35.9%, 64.5%, and 47.0% for DTR isolates and 60.5%, 80.6%, and 71.5% for MDR isolates.
MeSH term(s)	Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Pseudomonas aeruginosa ; Drug Resistance, Bacterial ; Ceftazidime/pharmacology ; Ceftazidime/therapeutic use ; Cephalosporins/pharmacology ; Cephalosporins/therapeutic use ; Pseudomonas Infections/drug therapy ; Anti-Infective Agents/pharmacology ; Azabicyclo Compounds/pharmacology ; Azabicyclo Compounds/therapeutic use ; Drug Combinations ; Microbial Sensitivity Tests ; Drug Resistance, Multiple, Bacterial
Chemical Substances	Anti-Bacterial Agents ; Ceftazidime (9M416Z9QNR) ; Cephalosporins ; Anti-Infective Agents ; Azabicyclo Compounds ; Drug Combinations
Language	English
Publishing date	2023-11-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	604920-5
ISSN	1879-0070 ; 0732-8893
ISSN (online)	1879-0070
ISSN	0732-8893
DOI	10.1016/j.diagmicrobio.2023.116130
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