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Article ; Online: How does the selection of national development zones affect urban green innovation?-Evidence from China.

Yu, Xiaolin / Wan, Kai

2022 Volume 17, Issue 8, Page(s) e0268111

Abstract: The launch of the selection process for National Development Zones(NDZs) marked a fundamental change in the construction of development zones, making it an essential position for local authorities to implement high-quality development. Based on the data ... ...

Abstract	The launch of the selection process for National Development Zones(NDZs) marked a fundamental change in the construction of development zones, making it an essential position for local authorities to implement high-quality development. Based on the data of prefecture-level cities in China from 2000 to 2018, this paper examines the impact and mechanism of selecting NDZs on urban green innovation through a double-difference spatial durbin model using the selection of NDZs as a "quasi-natural experiment". The study finds that the selection of NDZs can promote green innovation in cities and has a significant window-radiating effect. The heterogeneity test results show that the implementation of the selection policy for development zones in non-old industrial cities, large and medium-sized cities, cities with easy access to transportation, and cities with high market orientation are more likely to promote urban green innovation. At the same time, the higher the level of government governance and the better the level of economic development of the development zones, the more it helps to realize the effects of the selection policy. The results of the mechanism test show that the selection of NDZs has a positive impact on urban green innovation through environmental regulation effects, resource allocation effects, and policy amplification effects.
MeSH term(s)	China ; Cities ; Economic Development ; Government ; Industry
Language	English
Publishing date	2022-08-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0268111
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: How does the selection of national development zones affect urban green innovation?-Evidence from China.

Xiaolin Yu / Kai Wan

PLoS ONE, Vol 17, Iss 8, p e

2022 Volume 0268111

Abstract	The launch of the selection process for National Development Zones(NDZs) marked a fundamental change in the construction of development zones, making it an essential position for local authorities to implement high-quality development. Based on the data of prefecture-level cities in China from 2000 to 2018, this paper examines the impact and mechanism of selecting NDZs on urban green innovation through a double-difference spatial durbin model using the selection of NDZs as a "quasi-natural experiment". The study finds that the selection of NDZs can promote green innovation in cities and has a significant window-radiating effect. The heterogeneity test results show that the implementation of the selection policy for development zones in non-old industrial cities, large and medium-sized cities, cities with easy access to transportation, and cities with high market orientation are more likely to promote urban green innovation. At the same time, the higher the level of government governance and the better the level of economic development of the development zones, the more it helps to realize the effects of the selection policy. The results of the mechanism test show that the selection of NDZs has a positive impact on urban green innovation through environmental regulation effects, resource allocation effects, and policy amplification effects.
Keywords	Medicine ; R ; Science ; Q
Subject code	710
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Role of sestrins in metabolic and aging-related diseases.

Fang, Huan / Shi, Xiaomin / Wan, Juyi / Zhong, Xiaolin

Biogerontology

2023 Volume 25, Issue 1, Page(s) 9–22

Abstract: Sestrins are a type of highly conserved stress-inducing protein that has antioxidant and mTORC1 inhibitory functions. Metabolic dysfunction and aging are the main risk factors for development of human diseases, such as diabetes, neurodegenerative ... ...

Abstract	Sestrins are a type of highly conserved stress-inducing protein that has antioxidant and mTORC1 inhibitory functions. Metabolic dysfunction and aging are the main risk factors for development of human diseases, such as diabetes, neurodegenerative diseases, and cancer. Sestrins have important roles in regulating glucose and lipid metabolism, anti-tumor functions, and aging by inhibiting the reactive oxygen species and mechanistic target of rapamycin complex 1 pathways. In this review, the structure and biological functions of sestrins are summarized, and how sestrins are activated and contribute to regulation of the downstream signal pathways of metabolic and aging-related diseases are discussed in detail with the goal of providing new ideas and therapeutic targets for the treatment of related diseases.
MeSH term(s)	Humans ; Sestrins/metabolism ; Nuclear Proteins/metabolism ; Oxidative Stress/physiology ; Signal Transduction/physiology ; Aging ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Neoplasms ; Heat-Shock Proteins/metabolism
Chemical Substances	Sestrins ; Nuclear Proteins ; Mechanistic Target of Rapamycin Complex 1 (EC 2.7.11.1) ; Heat-Shock Proteins
Language	English
Publishing date	2023-07-30
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2047160-9
ISSN	1573-6768 ; 1389-5729
ISSN (online)	1573-6768
ISSN	1389-5729
DOI	10.1007/s10522-023-10053-y
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Article ; Online: Determination of the pressure and composition of wet gas fluid inclusions: An in situ Raman spectroscopic approach.

Li, Feiyang / Wan, Ye / Sun, Dongquan / Wang, Xiaolin / Hu, Wenxuan

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

2023 Volume 308, Page(s) 123774

Abstract: Carbonaceous fluid within mineral-hosted inclusions provides important information for carbon cycle in deep Earth. In addition to ... ...

Abstract	Carbonaceous fluid within mineral-hosted inclusions provides important information for carbon cycle in deep Earth. In addition to CH
Language	English
Publishing date	2023-12-18
Publishing country	England
Document type	Journal Article
ZDB-ID	210413-1
ISSN	1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
ISSN (online)	1873-3557
ISSN	0370-8322 ; 0584-8539 ; 1386-1425
DOI	10.1016/j.saa.2023.123774
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Article ; Online: Clinical Reasoning: A 30-Year-Old Woman Presenting With Rapidly Progressive Dementia and Extreme Hypoglycorrhachia.

Bai, Xiaolin / Xiang, Jingyan / Deng, Jiangshan / Ding, Wan Hai / Luan, Xinghua / Geng, Zhi

Neurology

2024 Volume 102, Issue 5, Page(s) e209188

Abstract: A 30-year-old woman presented with rapidly progressive dementia 1 month after the coronavirus disease 2019 infection. Repeated CSF analysis showed extreme hypoglycorrhachia, while cultures, metagenomic next-generation sequencing, and cytopathology ... ...

Abstract	A 30-year-old woman presented with rapidly progressive dementia 1 month after the coronavirus disease 2019 infection. Repeated CSF analysis showed extreme hypoglycorrhachia, while cultures, metagenomic next-generation sequencing, and cytopathology testing of CSF were negative. Laboratory investigations for possible etiologies revealed elevated blood ammonia and cancer antigen 125. Brain MRI demonstrated bilateral symmetric diffuse cortical lesions with mild hyperintensity on T1-weighted image and postcontrast enhancement. A more thorough history and specific examinations subsequently indicated an underlying etiology. This case provides an approach for evaluating young patients with rapidly progressive dementia, extreme hypoglycorrhachia, and diffuse CNS lesions, highlighting the importance of considering a broad differential diagnosis.
MeSH term(s)	Female ; Humans ; Adult ; Dementia/diagnosis ; Dementia/etiology ; Clinical Reasoning
Language	English
Publishing date	2024-02-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207147-2
ISSN	1526-632X ; 0028-3878
ISSN (online)	1526-632X
ISSN	0028-3878
DOI	10.1212/WNL.0000000000209188
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Article ; Online: Image Deblurring Based on an Improved CNN-Transformer Combination Network

Xiaolin Chen / Yuanyuan Wan / Donghe Wang / Yuqing Wang

Applied Sciences, Vol 13, Iss 1, p

2022 Volume 311

Abstract: Recently, using a CNN has been a common practice to restore blurry images due to its strong ability to learn feature information from large-scale datasets. However, CNNs essentially belong to local operations and have the defect of a limited receptive ... ...

Abstract	Recently, using a CNN has been a common practice to restore blurry images due to its strong ability to learn feature information from large-scale datasets. However, CNNs essentially belong to local operations and have the defect of a limited receptive field, which reduces the naturalness of deblurring results. Moreover, CNN-based deblurring methods usually adopt many downsample operations, which hinder detail recovery. Fortunately, transformers focus on modeling the global features, so they can cooperate with CNNs to enlarge the receptive field and compensate for the details lost as well. In this paper, we propose an improved CNN-transformer combination network for deblurring, which adopts a coarse-to-fine architecture as the backbone. To extract the local features and global features simultaneously, the common methods are two blocks connected in parallel or cascaded. Different from these, we design a local-global feature combination block (LGFCB) with a new connecting structure to better use the extracted features. The LGFCB comprises multi-scale residual blocks (MRB) and a transformer block. In addition, we adopt a channel attention fusion block (CAFB) in the encoder path to integrate features. To improve the ability of feature representation, in the decoder path, we introduce a supervised attention block (SAB) operated on restoration images to refine features. Numerous experiments on GoPro and RealBlur datasets indicated that our model achieves remarkable accuracy and processing speed.
Keywords	image deblurring ; coarse-to-fine strategy ; transformer ; CNN-transformer combination ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	006
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Study on the Efficacy of Ω Toenail Correction Treating Paronychia.

Liu, Yang / Lu, Wen / Zhang, Zhen / Wan, Hao / Wang, Kaiqi / Ding, Xiaolin

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons

2023

Abstract: To study the clinical effects of Ω toenail correction in the treatment of paronychia. One hundred thirty-six cases of 130 patients during the period from August 2018 to August 2021 were treated with Ω toenail correction according to clinical stages, the ... ...

Abstract	To study the clinical effects of Ω toenail correction in the treatment of paronychia. One hundred thirty-six cases of 130 patients during the period from August 2018 to August 2021 were treated with Ω toenail correction according to clinical stages, the clinical therapeutic effects of which were evaluated in terms of the operation time, the time to resume movement, treatment cycle, 1-y recurrence rate, and visual analogue scale (VAS) scores before and after treatment. The clinical efficacy was analyzed and compared of Ω toenail correction in treating paronychia of different clinical stages. It has been demonstrated that there was no significant difference in operation time, time to resume movement, treatment cycle and recurrence rate among different stages of paronychia, while there existed the significant difference (p < .05) in VAS score of resting-state pain before and after correction which stood at 6.43 ± 0.29 points with the after-treatment VAS scores at 1.10 ± 0.22. There is a statistical difference (p < .05) in VAS score of movement-evoked pain between before and after treatment. The VAS scores of movement-evoked pain stood at 7.55 ± 0.42, which is in contrast with the after-treatment VAS at 1.74 ± 0.93. It has been concluded that Ω toenail correction characterized by easy operation can relieve the pain immediately, which can achieve satisfactory clinical efficacy for treating paronychia of different stages.
Language	English
Publishing date	2023-08-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1146972-9
ISSN	1542-2224 ; 1067-2516
ISSN (online)	1542-2224
ISSN	1067-2516
DOI	10.1053/j.jfas.2023.05.010
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Article ; Online: The effect of the problem based learning teaching model combined with mind mapping on nursing teaching: A meta-analysis.

Gao, Xiaolin / Wang, Li / Deng, Jianjun / Wan, Chaomin / Mu, Dezhi

Nurse education today

2022 Volume 111, Page(s) 105306

Abstract: Background: To evaluate the effect of the problem-based learning (PBL) teaching model combined with mind mapping on nursing teaching.: Methods: The Cochrane Library, PubMed/MEDLINE, EBSCO, OVID, Science Citation Index (SCI), China Knowledge Resource ... ...

Abstract	Background: To evaluate the effect of the problem-based learning (PBL) teaching model combined with mind mapping on nursing teaching. Methods: The Cochrane Library, PubMed/MEDLINE, EBSCO, OVID, Science Citation Index (SCI), China Knowledge Resource Integrated (CNKI), VIP, WF and other databases were searched for studies published from 2000 to 2021 on the application of the PBL model in nursing teaching. Literature screening and data extraction were conducted by two independent evaluators based on inclusion and exclusion criteria, and heterogeneity was analysed. A meta-analysis was performed using RevMan 5.3 software. Results: A total of 1907 papers were initially retrieved, and 8 randomized controlled studies were eventually included in the meta-analysis after screening. Theoretical test scores, practical test scores, and students' self-learning ability in the experimental group were all significantly higher than those in the control group (P < 0.05); however, practical test scores were highly heterogeneous (I Conclusion: The PBL teaching model combined with mind mapping works well for nursing teaching in China. It can improve students' self-learning ability, which is conducive to Chinese nursing students mastering theoretical knowledge and improving practical abilities, and can be affected by a variety of factors in practical teaching.
MeSH term(s)	China ; Humans ; Knowledge ; Learning ; Problem-Based Learning ; Students, Nursing ; Teaching
Language	English
Publishing date	2022-02-26
Publishing country	Scotland
Document type	Journal Article ; Meta-Analysis
ZDB-ID	1062570-7
ISSN	1532-2793 ; 0260-6917
ISSN (online)	1532-2793
ISSN	0260-6917
DOI	10.1016/j.nedt.2022.105306
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Article ; Online: Topological Electronic Transition Contributing to Improved Thermoelectric Performance in p-Type Mg

Xie, Sen / Wan, Xiaolin / Wu, Yasong / Li, Chunxia / Yan, Fan / Ouyang, Yujie / Ge, Haoran / Li, Xianda / Liu, Yong / Wang, Rui / Toriyama, Michael Y / Snyder, G Jeffrey / Yang, Jiong / Zhang, Qingjie / Liu, Wei / Tang, Xinfeng

Advanced materials (Deerfield Beach, Fla.)

2024 , Page(s) e2400845

Abstract: Topological electronic transition is the very promising strategy for achieving high band degeneracy ( ... ...

Abstract	Topological electronic transition is the very promising strategy for achieving high band degeneracy (N
Language	English
Publishing date	2024-04-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.202400845
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Article: First Report of Black Leaf Spot Caused by

Yan, Mingfeng / Hu, Yanyue / Zhao, Xiaolin / Zeng, Rong / Wan, Chuanxu / Hua, Juling / Sun, Yang / Huang, Shuijin

Plant disease

2024

Abstract: Chinese yam (Dioscorea polystachya Turczaninow cv. Tiegun), which belongs to the family Dioscoreaceae, is widely cultivated throughout China due to its high economic and medicinal value. In June 2023, black leaf spots on Chinese yam (cv. Purple 1) were ... ...

Abstract	Chinese yam (Dioscorea polystachya Turczaninow cv. Tiegun), which belongs to the family Dioscoreaceae, is widely cultivated throughout China due to its high economic and medicinal value. In June 2023, black leaf spots on Chinese yam (cv. Purple 1) were observed in Nanchang city (28.45° N, 115.49° E) of Jiangxi province, southeastern China. The incidence of the disease ranged between 70 and 85% of plants, and up to 30% of the leaves per plant were affected in the field over a 2-week period of study. Infected foliage displayed brown necrotic lesions, elliptical or irregular, with yellow halo at the edge of the lesion (0.5 to 3 cm diam.). To identify the causal agent, 32 symptomatic leaves of eight symptomatic plants were collected. Small pieces from the margin of necrotic leaf tissue (about 3 x 3 mm) were surface sterilized in 75% ethanol for 30 s followed in 0.1% HgCl2 for 1 min, and washed three times with ddH2O. Then, the pieces were transferred onto potato dextrose agar (PDA) plates and incubated at 26°C for 3 days with a 12-h light-dark cycle. From the 32 isolates, 21 exhibited similar morphology after hyphal tipping resulting in an isolation frequency of 65.6%. Colonies on PDA were initially white aerial hyphae but became grayish with age, and a reddish orange pigment on the underside. After 16 days of incubation, pycnidia were observed, which were dark, spherical or flat spherical, and 64.1 to 172.5 µm (n = 25) in diameter. Conidia were ellipsoidal, aseptate, hyaline, and 4.1 to 5.6 × 1.8 to 2.7 µm (n = 80). In addition, a blackish green discoloration was produced on malt extract agar (MEA) using the NaOH spot test. The isolates were tentatively identified as Epicoccum spp. based on morphological characteristics (Chen et al. 2017). Isolate AYZ-1 was randomly selected for identification and pathogenicity testing. Genomic DNA of the isolate (AYZ-1) was extracted and amplified by polymerase chain reaction (PCR) using ITS1/ITS4 for the internal transcribed spacer (ITS) region (White et al. 1990), Btub2Fd/Btub4Rd for the β-tubulin (TUB) region (Woudenberg et al. 2009), LROR/LR7 for the large ribosomal RNA gene (LSU) region (Rehner and Samuels 1994), and RPB2-5F2/fRPB2-7cR for RNA polymerase II second largest subunit (RPB2) region (Liu et al. 1999), respectively. The concatenated sequences (GenBank Accession No. OR574165, OR567827, OR574166, OR567828, respectively) shared 99.8 to 100% identity with Epicoccum latusicollum (OP788080, MN329871, OR428532, and OL422485, respectively). A neighbor-joining phylogenetic tree was generated based on the concatenated sequences in MEGA7, placed isolate (AYZ-1) within E. latusicollum. To fulfill Koch's postulates, healthy leaflets from three one-year-old Chinese yam (cv. Purple 1) were used as inoculation materials, using isolate AYZ-1. Two sites of each leaf were wounded with a sterile needle and covered with a piece of cotton drenched with 200 µL spore suspension (106 conidia/mL) on the left sides, while sterilized water served as the control on the right sides of leaves. All inoculated leaves were covered with clear polyethylene bags for 24 h. Plants were grown outdoors at a daily average temperature of 26°C with relative humidity over 45%. After 7 days of incubation, the leaves showed the same symptoms as the original diseased leaves. The E. latusicollum isolate was re-isolated from diseased leaves and confirmed by morphology and sequencing analysis, fulfilling Koch's postulates. E. latusicollum has been previously reported to cause black root on yam in China's south-western province of Sichuan (Han et al. 2019). Meanwhile, leaf spot have been reported on many plants by this genus, such as tobacco (Guo et al. 2020) and banana (Liu et al. 2023). According to our knowledge, this is the first report of E. latusicollum causing black leaf spot on Chinese yam in China. This finding will provide an important reference for understanding the biology of E. latusicollum and the distribution of the disease, but more research is needed to determine if management is warranted.
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	754182-x
ISSN	0191-2917
ISSN	0191-2917
DOI	10.1094/PDIS-11-23-2409-PDN
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