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  1. Article ; Online: From the BCVS Chair.

    Liao, Ronglih

    Circulation research

    2018  Volume 120, Issue 11, Page(s) 1707–1708

    MeSH term(s) American Heart Association ; Anniversaries and Special Events ; Cardiovascular Diseases/therapy ; Congresses as Topic/trends ; Humans ; Leadership ; United States
    Language English
    Publishing date 2018-01-30
    Publishing country United States
    Document type News ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.117.310524
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  2. Article ; Online: Decoding the Nanoenvironment in Cardiac Amyloidosis Through Proteomics.

    Alexander, Kevin M / Jha, Alokkumar / Liao, Ronglih

    JACC. CardioOncology

    2020  Volume 2, Issue 4, Page(s) 644–646

    Language English
    Publishing date 2020-11-17
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2666-0873
    ISSN (online) 2666-0873
    DOI 10.1016/j.jaccao.2020.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Worming along in amyloid cardiotoxicity.

    Liao, Ronglih

    Blood

    2014  Volume 123, Issue 23, Page(s) 3525–3526

    MeSH term(s) Amyloidosis/diagnosis ; Animals ; Caenorhabditis elegans ; Female ; Heart Diseases/diagnosis ; Humans ; Immunoglobulin Light Chains/immunology ; Male
    Chemical Substances Immunoglobulin Light Chains
    Language English
    Publishing date 2014-06-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2014-04-566703
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  4. Article ; Online: Generation of two induced pluripotent stem cell lines from hereditary amyloidosis patients with polyneuropathy carrying heterozygous transthyretin (TTR) mutation

    Juan Melesio / Bernardo Bonilauri / Audrey Li / Paul D. Pang / Ronglih Liao / Ronald M. Witteles / Joseph C. Wu / Karim Sallam

    Stem Cell Research, Vol 74, Iss , Pp 103265- (2024)

    2024  

    Abstract: Hereditary transthyretin amyloidosis with polyneuropathy (ATTR-PN) results from specific TTR gene mutations. In this study, we generated two induced pluripotent stem cell (iPSC) lines derived from ATTR-PN patients with heterozygous TTR gene mutations ( ... ...

    Abstract Hereditary transthyretin amyloidosis with polyneuropathy (ATTR-PN) results from specific TTR gene mutations. In this study, we generated two induced pluripotent stem cell (iPSC) lines derived from ATTR-PN patients with heterozygous TTR gene mutations (Ala97Ser and Phe64Leu). These iPSC lines exhibited normal morphology, karyotype, high pluripotency marker expression, and differentiation into cells representing all germ layers. The generation of these iPSC lines serve as a valuable tool for investigating the mechanisms of ATTR-PN across various cell types and facilitating patient-specific in vitro amyloidosis modeling.
    Keywords hiPSC ; Stem cells ; Pluripotency ; TTR ; Transthyretin ; Polyneuropathy ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2024-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Elucidating effects of the environmental pollutant benzo[a]pyrene [BaP] on cardiac arrhythmogenicity.

    Yang, Johnson Y / Mondéjar-Parreño, Gema / Jahng, James W S / Lu, Yu / Hamburg, Naomi / Nadeau, Kari C / Conklin, Daniel J / Liao, Ronglih / Chandy, Mark / Wu, Joseph C

    Journal of molecular and cellular cardiology

    2024  Volume 191, Page(s) 23–26

    Language English
    Publishing date 2024-04-20
    Publishing country England
    Document type Letter
    ZDB-ID 80157-4
    ISSN 1095-8584 ; 0022-2828
    ISSN (online) 1095-8584
    ISSN 0022-2828
    DOI 10.1016/j.yjmcc.2024.04.013
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  6. Article ; Online: Amyloid Cardiomyopathy: Disease on the Rise.

    Liao, Ronglih / Ward, Jennifer E

    Circulation research

    2017  Volume 120, Issue 12, Page(s) 1865–1867

    MeSH term(s) Amyloidosis/diagnosis ; Amyloidosis/epidemiology ; Animals ; Biomedical Research/trends ; Cardiomyopathies/diagnosis ; Cardiomyopathies/epidemiology ; Humans
    Language English
    Publishing date 2017-06-09
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.117.310643
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  7. Article ; Online: Thomas L. Force, MD: 1951-2020: A Brilliant Physician-Scientist Gone Too Soon.

    Koch, Walter J / Vagnozzi, Ronald J / Wang, Thomas J / Liao, Ronglih / Houser, Steven R

    Circulation research

    2021  Volume 128, Issue 1, Page(s) 6–7

    Language English
    Publishing date 2021-01-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.120.318673
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  8. Article ; Online: Generation of two induced pluripotent stem cell lines from hereditary amyloidosis patients with polyneuropathy carrying heterozygous transthyretin (TTR) mutation.

    Melesio, Juan / Bonilauri, Bernardo / Li, Audrey / Pang, Paul D / Liao, Ronglih / Witteles, Ronald M / Wu, Joseph C / Sallam, Karim

    Stem cell research

    2023  Volume 74, Page(s) 103265

    Abstract: Hereditary transthyretin amyloidosis with polyneuropathy (ATTR-PN) results from specific TTR gene mutations. In this study, we generated two induced pluripotent stem cell (iPSC) lines derived from ATTR-PN patients with heterozygous TTR gene mutations ( ... ...

    Abstract Hereditary transthyretin amyloidosis with polyneuropathy (ATTR-PN) results from specific TTR gene mutations. In this study, we generated two induced pluripotent stem cell (iPSC) lines derived from ATTR-PN patients with heterozygous TTR gene mutations (Ala97Ser and Phe64Leu). These iPSC lines exhibited normal morphology, karyotype, high pluripotency marker expression, and differentiation into cells representing all germ layers. The generation of these iPSC lines serve as a valuable tool for investigating the mechanisms of ATTR-PN across various cell types and facilitating patient-specific in vitro amyloidosis modeling.
    MeSH term(s) Humans ; Induced Pluripotent Stem Cells/metabolism ; Prealbumin/genetics ; Prealbumin/metabolism ; Amyloid Neuropathies, Familial/genetics ; Amyloid Neuropathies, Familial/metabolism ; Polyneuropathies/genetics ; Polyneuropathies/metabolism ; Mutation/genetics
    Chemical Substances Prealbumin
    Language English
    Publishing date 2023-11-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393143-7
    ISSN 1876-7753 ; 1873-5061
    ISSN (online) 1876-7753
    ISSN 1873-5061
    DOI 10.1016/j.scr.2023.103265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Fortune Favors the Prepared: Safety and Efficacy of Allogeneic Hypoxia Preconditioned Mesenchymal Stromal Cells in Primates.

    Kuster, Gabriela M / Liao, Ronglih

    Circulation research

    2016  Volume 118, Issue 6, Page(s) 908–910

    MeSH term(s) Animals ; Ischemic Preconditioning, Myocardial/methods ; Male ; Mesenchymal Stem Cell Transplantation/methods ; Mesenchymal Stromal Cells/physiology ; Myocardial Infarction/therapy ; Myocardial Revascularization ; Paracrine Communication/physiology
    Language English
    Publishing date 2016-03-18
    Publishing country United States
    Document type Comment ; Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.116.308410
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  10. Article ; Online: Harnessing Cardiac Regeneration as a Potential Therapeutic Strategy for AL Cardiac Amyloidosis.

    Joshi, Shaurya / Evangelisti, Alessandro / Liao, Ronglih / Alexander, Kevin M

    Current cardiology reports

    2020  Volume 22, Issue 1, Page(s) 1

    Abstract: Purpose of review: Cardiac regeneration has received much attention as a possible means to treat various forms of cardiac injury. This review will explore the field of cardiac regeneration by highlighting the existing animal models, describing the ... ...

    Abstract Purpose of review: Cardiac regeneration has received much attention as a possible means to treat various forms of cardiac injury. This review will explore the field of cardiac regeneration by highlighting the existing animal models, describing the involved molecular pathways, and discussing attempts to harness cardiac regeneration to treat cardiomyopathies.
    Recent findings: Light chain cardiac amyloidosis is a degenerative disease characterized by progressive heart failure due to amyloid fibril deposition and light chain-mediated cardiotoxicity. Recent findings in a zebrafish model of light chain amyloidosis suggest that cardiac regenerative confers a protective effect against this disease. Cardiac regeneration remains an intriguing potential tool for treating cardiovascular disease. Degenerative diseases, such as light chain cardiac amyloidosis, may be particularly suited for therapeutic interventions that target cardiac regeneration. Further studies are needed to translate preclinical findings for cardiac regeneration into effective therapies.
    MeSH term(s) Amyloidosis/complications ; Amyloidosis/diagnosis ; Animals ; Cardiomyopathies/complications ; Cardiomyopathies/metabolism ; Cardiomyopathies/therapy ; Cardiotoxicity/physiopathology ; Heart Failure/diagnosis ; Heart Failure/etiology ; Humans ; Immunoglobulin Light Chains/metabolism ; Myocardium/pathology ; Regeneration ; Zebrafish
    Chemical Substances Immunoglobulin Light Chains
    Language English
    Publishing date 2020-01-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2055373-0
    ISSN 1534-3170 ; 1523-3782
    ISSN (online) 1534-3170
    ISSN 1523-3782
    DOI 10.1007/s11886-020-1252-3
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