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  1. Article: Lipids, hormones, and gastric bypass.

    Penland, Heath R

    The American journal of psychiatry

    2006  Volume 163, Issue 6, Page(s) 1113; author reply 1113–4

    MeSH term(s) Adipose Tissue/metabolism ; Brain/physiopathology ; Gastric Bypass/adverse effects ; Humans ; Lipid Metabolism/physiology ; Lipids/physiology ; Psychotic Disorders/etiology ; Psychotic Disorders/physiopathology ; Steroids/metabolism ; Steroids/physiology ; Weight Loss/physiology
    Chemical Substances Lipids ; Steroids
    Language English
    Publishing date 2006-06
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/ajp.2006.163.6.1113a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Combined use of lamotrigine and electroconvulsive therapy in bipolar depression: a case series.

    Penland, Heath R / Ostroff, Robert B

    The journal of ECT

    2006  Volume 22, Issue 2, Page(s) 142–147

    Abstract: Objective: Lamotrigine and electroconvulsive therapy (ECT) are both safe and effective treatments for bipolar depression. Concerns exist that anticonvulsants may interfere with seizure expression during ECT or may exacerbate cognitive side effects, ... ...

    Abstract Objective: Lamotrigine and electroconvulsive therapy (ECT) are both safe and effective treatments for bipolar depression. Concerns exist that anticonvulsants may interfere with seizure expression during ECT or may exacerbate cognitive side effects, potentially affecting clinical response. This report examines the clinical use of concurrent ECT and lamotrigine for acute bipolar depression and the transition to maintenance therapy.
    Methods: Nine patients with acute bipolar depression were simultaneously treated with a course of ECT while titrating lamotrigine for maintenance therapy. We compared mean stimulus intensity, mean seizure duration, and mean time to orientation after treatment for each patient during treatment with their highest and lowest lamotrigine dose.
    Results: All 9 patients were treated to remission. From the lowest daily dose to the highest daily dose, mean increase in lamotrigine was 102.8 mg. Clinically adequate seizures were obtained in each patient. Lamotrigine had minimal effect on each measured ECT parameter. The interval between ECT treatments was spaced to a mean of 15.2 days. The treatment combination was well tolerated, with no serious adverse events, no rashes, and no worsening of cognitive side effects.
    Conclusions: Concurrent use of lamotrigine with ECT in bipolar depression seems safe, did not interfere with routine ECT practice, and allowed for transition to maintenance pharmacotherapy.
    MeSH term(s) Adult ; Aged ; Antidepressive Agents/therapeutic use ; Bipolar Disorder/drug therapy ; Bipolar Disorder/therapy ; Combined Modality Therapy ; Electroconvulsive Therapy ; Female ; Humans ; Lamotrigine ; Male ; Middle Aged ; Triazines/therapeutic use
    Chemical Substances Antidepressive Agents ; Triazines ; Lamotrigine (U3H27498KS)
    Language English
    Publishing date 2006-06-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1426385-3
    ISSN 1533-4112 ; 1095-0680
    ISSN (online) 1533-4112
    ISSN 1095-0680
    DOI 10.1097/00124509-200606000-00013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The catatonic dilemma expanded.

    Penland, Heath R / Weder, Natalie / Tampi, Rajesh R

    Annals of general psychiatry

    2006  Volume 5, Page(s) 14

    Abstract: Catatonia is a common syndrome that was first described in the literature by Karl Kahlbaum in 1874. The literature is still developing and remains unclear on many issues, especially classification, diagnosis, and pathophysiology. Clinicians caring for ... ...

    Abstract Catatonia is a common syndrome that was first described in the literature by Karl Kahlbaum in 1874. The literature is still developing and remains unclear on many issues, especially classification, diagnosis, and pathophysiology. Clinicians caring for psychiatric patients with catatonic syndromes continue to face many dilemmas in diagnosis and treatment. We discuss many of the common problems encountered in the care of a catatonic patient, and discuss each problem with a review of the literature. Focus is on practical aspects of classification, epidemiology, differential diagnosis, treatment, medical comorbidity, cognition, emotion, prognosis, and areas for future research in catatonic syndromes.
    Language English
    Publishing date 2006-09-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2090401-0
    ISSN 1744-859X ; 1744-859X ; 1475-2832
    ISSN (online) 1744-859X
    ISSN 1744-859X ; 1475-2832
    DOI 10.1186/1744-859X-5-14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Catatonia: a review.

    Weder, Natalie D / Muralee, Sunanda / Penland, Heath / Tampi, Rajesh R

    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists

    2008  Volume 20, Issue 2, Page(s) 97–107

    Abstract: Background: To write an up-to-date review paper on catatonia using published literature.: Methods: This review involved a search using the terms "catatonia," "stupor," "catatonic schizophrenia" and "catalepsy" in the Cochrane Database of Systematic ... ...

    Abstract Background: To write an up-to-date review paper on catatonia using published literature.
    Methods: This review involved a search using the terms "catatonia," "stupor," "catatonic schizophrenia" and "catalepsy" in the Cochrane Database of Systematic Reviews, the Medline database and EMBASE and PsychINFO. Additional use was made of these databases in searching for randomized controlled trials, meta-analyses, cohort studies, case-control studies, case series, case reports and reviews.
    Results: Available evidence indicates that catatonia is a common neuropsychiatric syndrome characterized by the presence of various motor signs and symptoms. The underlying pathophysiologic-mechanisms points to a heterogeneous group of etiologies. Current classifications are based on the type of presentation and the duration of symptoms; agitated versus retarded and acute versus chronic. Available data supports the efficacy of benzodiazepines and electroconvulsive therapy (ECT) in the treatment of this condition, but the treatment response is limited by the chronicity of symptoms.
    Conclusions: Catatonia is a common disorder that occurs in a wide variety of psychiatric, neurological and medical conditions. At the current time, there is sufficient evidence to consider it as a specific nosologic syndrome with different subtypes and treatment responses.
    MeSH term(s) Catatonia/classification ; Catatonia/diagnosis ; Catatonia/drug therapy ; Catatonia/etiology ; Humans
    Language English
    Publishing date 2008-04
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 1025337-3
    ISSN 1547-3325 ; 1040-1237
    ISSN (online) 1547-3325
    ISSN 1040-1237
    DOI 10.1080/10401230802017092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The catatonic dilemma expanded

    Weder Natalie / Penland Heath R / Tampi Rajesh R

    Annals of General Psychiatry, Vol 5, Iss 1, p

    2006  Volume 14

    Abstract: Abstract Catatonia is a common syndrome that was first described in the literature by Karl Kahlbaum in 1874. The literature is still developing and remains unclear on many issues, especially classification, diagnosis, and pathophysiology. Clinicians ... ...

    Abstract Abstract Catatonia is a common syndrome that was first described in the literature by Karl Kahlbaum in 1874. The literature is still developing and remains unclear on many issues, especially classification, diagnosis, and pathophysiology. Clinicians caring for psychiatric patients with catatonic syndromes continue to face many dilemmas in diagnosis and treatment. We discuss many of the common problems encountered in the care of a catatonic patient, and discuss each problem with a review of the literature. Focus is on practical aspects of classification, epidemiology, differential diagnosis, treatment, medical comorbidity, cognition, emotion, prognosis, and areas for future research in catatonic syndromes.
    Keywords Psychiatry ; RC435-571 ; Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Psychiatry ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2006-09-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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