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Article ; Online: Body Composition of Infants With Congenital Gastroschisis.

McNelis, Kera / Poindexter, Anne / Goddard, Gillian / Riddle, Stefanie / Wessel, Jacqueline / Helmrath, Michael

Journal of pediatric gastroenterology and nutrition

2021 Volume 74, Issue 2, Page(s) e35–e38

Abstract: Abstract: Infants born with congenital gastroschisis are at risk for intrauterine growth restriction, small for gestational size at birth, and growth failure during the newborn period despite advanced care. Body composition provides a more complete ... ...

Abstract	Abstract: Infants born with congenital gastroschisis are at risk for intrauterine growth restriction, small for gestational size at birth, and growth failure during the newborn period despite advanced care. Body composition provides a more complete picture of proportional growth than weight and length alone. Fat-free mass (FFM) represents organ growth, and in preterm infants without gastroschisis, improved FFM deposition is associated with improved neurodevelopmental outcomes. There is limited literature regarding the body composition of infants with gastroschisis. This case series describes the body composition of 10 infants with gastroschisis.
MeSH term(s)	Body Composition ; Fetal Growth Retardation ; Gastroschisis/surgery ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Infant, Premature
Language	English
Publishing date	2021-08-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	603201-1
ISSN	1536-4801 ; 0277-2116
ISSN (online)	1536-4801
ISSN	0277-2116
DOI	10.1097/MPG.0000000000003288
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Article ; Online: Phthalate exposure in the neonatal intensive care unit is associated with development of bronchopulmonary dysplasia.

Stroustrup, Annemarie / Zhang, Xueying / Spear, Emily / Bandyopadhyay, Sanjukta / Narasimhan, Srinivasan / Meher, Anil K / Choi, Jaeun / Qi, Gao / Poindexter, Brenda B / Teitelbaum, Susan L / Andra, Syam S / Gennings, Chris / Aschner, Judy L

Environment international

2023 Volume 178, Page(s) 108117

Abstract: Objective: Bronchopulmonary dysplasia (BPD) is a serious yet common morbidity of preterm birth. Although prior work suggests a possible role for phthalate exposure in the development of BPD, no study has rigorously evaluated this. Our objective was to ... ...

Abstract	Objective: Bronchopulmonary dysplasia (BPD) is a serious yet common morbidity of preterm birth. Although prior work suggests a possible role for phthalate exposure in the development of BPD, no study has rigorously evaluated this. Our objective was to determine whether hospital-based phthalate exposure is associated with the development of BPD and to identify developmental windows sensitive to exposure. Study design: This is a prospective multicenter cohort study of 360 preterm infants born at 23-33 weeks gestation participating in the Developmental Impact of NICU Exposures (DINE) cohort. 939 urine specimens collected during the NICU stay were analyzed for biomarkers of phthalate exposure by liquid chromatography with tandem mass spectrometry. The modified Shennan definition was used to diagnose bronchopulmonary dysplasia. Reverse distributed-lag modeling identified developmental windows sensitive to specific phthalate exposure, controlling for relevant covariates including sex and respiratory support. Results: Thirty-five percent of participants were diagnosed with BPD. Exposure to specific phthalate mixtures at susceptible points in preterm infant development are associated with later diagnosis of BPD in models adjusted for use of respiratory support. The weighted influence of specific phthalate metabolites in the mixtures varied by sex. Metabolites of di(2-ethylhexyl) phthalate, a phthalate previously linked to neonatal respiratory support equipment, drove this association, particularly among female infants, at 26- to 30-weeks post-menstrual age. Conclusions: This is the largest and only multi-site study of NICU-based phthalate exposure and clinical impact yet reported. In well-constructed models accounting for infant sex and respiratory support, we found a significant positive association between ultimate diagnosis of BPD and prior exposure to phthalate mixtures with DEHP predominance at 26- to 30-weeks PMA or 34-36-weeks PMA. This information is critically important as it identifies a previously unrecognized and modifiable contributing factor to BPD.
MeSH term(s)	Infant ; Child ; Infant, Newborn ; Humans ; Female ; Infant, Premature ; Intensive Care Units, Neonatal ; Bronchopulmonary Dysplasia/epidemiology ; Bronchopulmonary Dysplasia/diagnosis ; Cohort Studies ; Prospective Studies ; Premature Birth ; Gestational Age
Chemical Substances	phthalic acid (6O7F7IX66E)
Language	English
Publishing date	2023-07-26
Publishing country	Netherlands
Document type	Multicenter Study ; Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2023.108117
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Zs.A 3131: Show issues

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Article ; Online: Psychological distress among postpartum women who took opioids during pregnancy: the role of perceived stigma in healthcare settings.

Bann, Carla M / Okoniewski, Katherine C / Clarke, Leslie / Wilson-Costello, Deanne / Merhar, Stephanie / DeMauro, Sara / Lorch, Scott / Ambalavanan, Namasivayam / Peralta-Carcelen, Myriam / Limperopoulos, Catherine / Poindexter, Brenda / Davis, Jonathan M / Walsh, Michele / Newman, Jamie

Archives of women's mental health

2023 Volume 27, Issue 2, Page(s) 275–283

Abstract: This study examined the relationship between perceived stigma in healthcare settings during pregnancy and psychological distress and well-being in the postpartum period among individuals who took opioids while pregnant. Analyses included 134 birth ... ...

Abstract	This study examined the relationship between perceived stigma in healthcare settings during pregnancy and psychological distress and well-being in the postpartum period among individuals who took opioids while pregnant. Analyses included 134 birth mothers of opioid-exposed infants. At 0-1 months postpartum, perceived stigma and psychological distress were measured using the Prenatal Opioid use Perceived Stigma scale and measures from the Patient-Reported Outcome Measurement Information System (PROMIS). Food insecurity, housing instability, and Adverse Childhood Experiences (ACEs) were also assessed. Linear and generalized linear mixed-effect models were conducted to compare PROMIS scale scores and unmet needs by stigma, adjusting for site/location, age, race/ethnicity, marital status, education, public insurance, and parity. More than half of participants (54%) perceived stigma in healthcare settings. Individuals reporting stigma had higher depression, anxiety, and anger scores (p < 0.001) indicating greater psychological distress in the postpartum period compared to those reporting no stigma, after controlling for demographic characteristics. In addition, they scored significantly lower on the PROMIS meaning and purpose scale, an indicator of well-being (p = 0.002). Those reporting stigma were more likely to have food insecurity (p = 0.003), three or more ACEs (p = 0.040), verbal or physical abuse during pregnancy (p < 0.001), and less emotional support (p = 0.006) than those who did not. An association was observed between perceived stigma in the prenatal period and psychological distress in the postpartum period, providing support for stigma reduction interventions and education for healthcare providers on trauma-informed care.
MeSH term(s)	Pregnancy ; Infant ; Female ; Humans ; Analgesics, Opioid ; Stress, Psychological/psychology ; Postpartum Period/psychology ; Delivery of Health Care ; Psychological Distress
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2023-11-13
Publishing country	Austria
Document type	Journal Article
ZDB-ID	1463529-X
ISSN	1435-1102 ; 1434-1816
ISSN (online)	1435-1102
ISSN	1434-1816
DOI	10.1007/s00737-023-01390-5
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Zs.A 5115: Show issues

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Article: BIOLOGICAL PROPERTIES AND CLASSIFICATION OF THE CAULOBACTER GROUP.

POINDEXTER, J S

Bacteriological reviews

2003 Volume 28, Page(s) 231–295

MeSH term(s)	Bacteria ; Bacteriophages ; Caulobacter ; Cell Division ; Classification ; Ecology ; Electrons ; Metabolism ; Microscopy ; Microscopy, Electron ; Microscopy, Phase-Contrast ; Research
Language	English
Publishing date	2003-08-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	207943-4
ISSN	0005-3678
ISSN	0005-3678
DOI	10.1128/br.28.3.231-295.1964
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Ud II Zs.96: Show issues

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Article ; Online: Eating, Sleeping, Consoling for Neonatal Opioid Withdrawal (ESC-NOW): a Function-Based Assessment and Management Approach study protocol for a multi-center, stepped-wedge randomized controlled trial.

Young, Leslie W / Ounpraseuth, Songthip / Merhar, Stephanie L / Simon, Alan E / Das, Abhik / Greenberg, Rachel G / Higgins, Rosemary D / Lee, Jeannette / Poindexter, Brenda B / Smith, P Brian / Walsh, Michele / Snowden, Jessica / Devlin, Lori A

Trials

2022 Volume 23, Issue 1, Page(s) 638

MeSH term(s)	Analgesics, Opioid/adverse effects ; Humans ; Infant, Newborn ; Multicenter Studies as Topic ; Randomized Controlled Trials as Topic ; Research Design ; Sample Size
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2022-08-09
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-022-06445-z
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Article ; Online: White Matter Injury and Structural Anomalies in Infants with Prenatal Opioid Exposure.

Merhar, S L / Parikh, N A / Braimah, A / Poindexter, B B / Tkach, J / Kline-Fath, B

AJNR. American journal of neuroradiology

2019 Volume 40, Issue 12, Page(s) 2161–2165

Abstract: Previous studies have not found structural injury or brain malformations in infants and children with prenatal opioid exposure. As part of an ongoing study evaluating neuroimaging in infants with prenatal opioid exposure, we reviewed structural brain MR ... ...

Abstract	Previous studies have not found structural injury or brain malformations in infants and children with prenatal opioid exposure. As part of an ongoing study evaluating neuroimaging in infants with prenatal opioid exposure, we reviewed structural brain MR imaging in 20 term infants with prenatal opioid exposure and 20 term controls at 4-8 weeks of age. We found that 8 of the 20 opioid-exposed infants had punctate white matter lesions or white matter signal abnormality on structural MR imaging, and 2 of the opioid-exposed infants had a septopreoptic fusion anomaly. No controls had white matter injury or structural malformations. Our findings underscore the importance of clinical neurodevelopmental follow-up and the need for more comprehensive imaging and long-term outcomes research following prenatal opioid exposure.
MeSH term(s)	Analgesics, Opioid/adverse effects ; Brain/drug effects ; Brain/pathology ; Female ; Humans ; Infant ; Infant, Newborn ; Longitudinal Studies ; Magnetic Resonance Imaging/methods ; Male ; Neuroimaging/methods ; Pregnancy ; Prenatal Exposure Delayed Effects/pathology ; White Matter/drug effects ; White Matter/pathology
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2019-10-17
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	603808-6
ISSN	1936-959X ; 0195-6108
ISSN (online)	1936-959X
ISSN	0195-6108
DOI	10.3174/ajnr.A6282
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Zs.A 1580: Show issues

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Article ; Online: Rising occurrence of hypocitraturia and hyperoxaluria associated with increasing prevalence of stone disease in calcium kidney stone formers.

Youssef, Ramy F / Martin, Jeremy W / Sakhaee, Khashayar / Poindexter, John / Dianatnejad, Sharmin / Scales, Charles D / Preminger, Glenn M / Lipkin, Michael E

Scandinavian journal of urology

2020 Volume 54, Issue 5, Page(s) 426–430

Abstract: Objective: To evaluate metabolic risk factors in calcium kidney stone formers from two different decades, comparing changes in metabolic profiles over time.: Methods: A retrospective analysis was performed of calcium kidney stone formers who ... ...

Abstract	Objective: To evaluate metabolic risk factors in calcium kidney stone formers from two different decades, comparing changes in metabolic profiles over time. Methods: A retrospective analysis was performed of calcium kidney stone formers who underwent metabolic evaluation of urolithiasis with 24-hour urine collections at a single institution. There were 309 patients evaluated from 1988 to 1994 (Group A), and 229 patients from 2007 to 2010 (Group B). A comparison between both groups was performed to assess changes in demographics and in metabolic stone profiles. Results: Comparing Group A to Group B, the percentage of females increased from 43 to 56%, obese patients (BMI ≥ 30) increased from 22 to 35%, and patients ≥ 50 years increased from 29 to 47% (all Conclusions: Urolithiasis has increased in females, obese, and older patients, consistent with population-based studies. We report a rising incidence of hypocitraturia and hyperoxaluria in the contemporary cohort, particularly in obese patients and in males, respectively. Further studies are needed to better characterize the metabolic changes corresponding to the increase in stone disease.
MeSH term(s)	Calcium ; Female ; Humans ; Hyperoxaluria/complications ; Hyperoxaluria/epidemiology ; Kidney Calculi/epidemiology ; Kidney Calculi/etiology ; Male ; Middle Aged ; Prevalence ; Recurrence ; Retrospective Studies ; Risk Factors
Chemical Substances	Calcium (SY7Q814VUP)
Language	English
Publishing date	2020-07-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2701936-6
ISSN	2168-1813 ; 2168-1805
ISSN (online)	2168-1813
ISSN	2168-1805
DOI	10.1080/21681805.2020.1794955
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Zs.A 601: Show issues

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Article: A multiple channel electronic stethoscope for teaching and demonstration.

BUTTERWORTH, J S / POINDEXTER, C A

American heart journal

2008 Volume 36, Issue 1, Page(s) 112–114

MeSH term(s)	Electronics ; Humans ; Stethoscopes
Language	English
Publishing date	2008-08-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	80026-0
ISSN	1097-6744 ; 0002-8703
ISSN (online)	1097-6744
ISSN	0002-8703
DOI	10.1016/0002-8703(48)90550-x
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Ui IV Zs.15: Show issues

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Article ; Online: Spatiotemporal Co-occurrence of Flanders and West Nile Viruses Within Culex Populations in Shelby County, Tennessee.

Lucero, D E / Carlson, T C / Delisle, J / Poindexter, S / Jones, T F / Moncayo, A C

Journal of medical entomology

2016 Volume 53, Issue 3, Page(s) 526–532

Abstract: West Nile virus (WNV) and Flanders virus (FLAV) can cocirculate in Culex mosquitoes in parts of North America. A large dataset of mosquito pools tested for WNV and FLAV was queried to understand the spatiotemporal relationship between these two viruses ... ...

Abstract	West Nile virus (WNV) and Flanders virus (FLAV) can cocirculate in Culex mosquitoes in parts of North America. A large dataset of mosquito pools tested for WNV and FLAV was queried to understand the spatiotemporal relationship between these two viruses in Shelby County, TN. We found strong evidence of global clustering (i.e., spatial autocorrelation) and overlapping of local clustering (i.e., Hot Spots based on Getis Ord Gi*) of maximum likelihood estimates (MLE) of infection rates (IR) during 2008-2013. Temporally, FLAV emerges and peaks on average 10.2 wk prior to WNV based on IR. Higher levels of WNV IR were detected within 3,000 m of FLAV-positive pool buffers than outside these buffers.
MeSH term(s)	Animal Distribution ; Animals ; Culex/growth & development ; Culex/virology ; Female ; Insect Vectors/growth & development ; Insect Vectors/virology ; Male ; Rhabdoviridae/genetics ; Rhabdoviridae/isolation & purification ; Rhabdoviridae/physiology ; Seasons ; Tennessee ; West Nile virus/genetics ; West Nile virus/isolation & purification ; West Nile virus/physiology
Language	English
Publishing date	2016
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	410635-0
ISSN	1938-2928 ; 0022-2585
ISSN (online)	1938-2928
ISSN	0022-2585
DOI	10.1093/jme/tjw011
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Zs.A 303: Show issues

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Article ; Online: Innovative strategies to improve diabetes outcomes in disadvantaged populations.

Ruddock, J S / Poindexter, M / Gary-Webb, T L / Walker, E A / Davis, N J

Diabetic medicine : a journal of the British Diabetic Association

2016 Volume 33, Issue 6, Page(s) 723–733

Abstract: Diabetes disproportionately affects disadvantaged populations. Eighty percent of deaths directly caused by diabetes occurred in low- and middle-income countries. In high-income countries, there are marked disparities in diabetes control among racial/ ... ...

Abstract	Diabetes disproportionately affects disadvantaged populations. Eighty percent of deaths directly caused by diabetes occurred in low- and middle-income countries. In high-income countries, there are marked disparities in diabetes control among racial/ethnic minorities and those with low socio-economic status. Innovative, effective and cost-effective strategies are needed to improve diabetes outcomes in these populations. Technological advances, peer educators and community health workers have expanded methodologies to reach, educate and monitor individuals with diabetes. In the present manuscript we review the outcomes of these strategies, and describe the barriers to and facilitators of these approaches for improving diabetes outcomes.
Language	English
Publishing date	2016-06
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	605769-x
ISSN	1464-5491 ; 0742-3071 ; 1466-5468
ISSN (online)	1464-5491
ISSN	0742-3071 ; 1466-5468
DOI	10.1111/dme.13088
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