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Article ; Online: Semblance of a physician

Gabriel Lavorato Neto / Egberto Ribeiro Turato / Maria Cândida Ribeiro Parisi

Interface: Comunicação, Saúde, Educação, Vol

medical students’ experiences during Type 2 Diabetes Mellitus clinic simulation

2023 Volume 27

Abstract: This qualitative research aimed to understand the experiences of a fourth-year medical class during two clinical simulation scenarios of type 2 diabetes management in Primary Care. Ten simulated students were interviewed. The results describe the ... ...

Abstract	This qualitative research aimed to understand the experiences of a fourth-year medical class during two clinical simulation scenarios of type 2 diabetes management in Primary Care. Ten simulated students were interviewed. The results describe the symbolic conception of diabetes and its treatment as anguish, damage, condemnation and an unpleasant sentence that affects the appropriation and performance of the medical role by students. Considering Medical Psychology, we suggest that such subjective factors should be addressed in teaching-learning in addition to commonly cognitive aspects mentioned in the medical education literature in order for students to develop the work profile to cope with diabetes in Primary Care. Clinical simulation facilitates the subjective approach through its group support component to promote reflection, insights and self-awareness.
Keywords	Simulation training ; Type 2 Diabetes Mellitus ; Education ; medical ; undergraduate ; Physician’s role ; Psychology ; Public aspects of medicine ; RA1-1270
Subject code	370
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Faculdade de Medicina de Botucatu (Unesp)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Higher systemic inflammatory status and cardiovascular risk associated with Charcot arthropathy unrelated to infection or extremity amputation.

de Vasconcelos, Jessica Castro / Atala, Yeelen Ballesteros / Zantut-Wittmann, Denise Engelbrecht / Parisi, Maria Cândida Ribeiro

Journal of diabetes and metabolic disorders

2022 Volume 21, Issue 2, Page(s) 1407–1413

Abstract: Purpose: People with diabetes and Charcot arthropathy have higher mortality than people with diabetes without this complication. Are the causes of this higher mortality exclusively infectious or of a cardiovascular origin? We aimed to study aspects ... ...

Abstract	Purpose: People with diabetes and Charcot arthropathy have higher mortality than people with diabetes without this complication. Are the causes of this higher mortality exclusively infectious or of a cardiovascular origin? We aimed to study aspects related to cardiovascular risk and inflammation in a population of people with type 2 diabetes with and without Charcot arthropathy. Methods: A cross-sectional study was performed in people with diabetes and Charcot Eickenholtz III arthropathy, matched for sex and age, with two groups of people with diabetes without Charcot arthropathy with and without peripheral sensory-motor neuropathy, in the absence of active infection. All participants underwent clinical and laboratory evaluation at the time of the interview, and their cardiovascular risk was calculated according to the United Kingdom Prospective Diabetes Study (UKPDS) calculator. Results: We evaluated 69 people with type 2 diabetes (21 with Charcot arthropathy, 24 with diabetic peripheral neuropathy and 24 without this neuropathy), with a mean age between 57 and 61 years and with a diabetes duration of more than 10 years. Patients with Charcot arthropathy had a longer duration of diabetes; more frequency of dyslipidemia; and higher levels of uric acid, microalbuminuria and C-reactive protein than the other two groups. A total of 73.9% of the people evaluated had high or very high cardiovascular risk according to the UKPDS score. Conclusion: The people with type 2 diabetes presenting Charcot arthropathy had greater values of systemic inflammatory parameters, even in the chronic phase of the complication, with a higher risk of mortality unrelated to infections.
Language	English
Publishing date	2022-06-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2680289-2
ISSN	2251-6581
ISSN	2251-6581
DOI	10.1007/s40200-022-01073-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The COVID-19 pandemic and the challenge of using technology for medical education in low and middle income countries

Dario Cecilio-Fernandes / Maria Cândida Ribeiro Parisi / Thiago M. Santos / John Sandars

MedEdPublish, Vol 9, Iss

2020 Volume 1

Abstract: The current use of technology for medical education in low and middle income countries (LMIC) during the COVID-19 pandemic is not yet reaching its potential. We provide recommendations for LMIC that has focus on a systematic framework that considers both ...

Abstract	The current use of technology for medical education in low and middle income countries (LMIC) during the COVID-19 pandemic is not yet reaching its potential. We provide recommendations for LMIC that has focus on a systematic framework that considers both faculty development and developing the skills of students. An enormous challenge for all medical educators, but especially in LMIC, continues to be how to maintain clinical teaching in these extraordinary times.
Keywords	COVID-19 ; faculty development ; online teaching and learning ; low and middle income countries ; medical education ; Special aspects of education ; LC8-6691 ; Medicine ; R ; covid19
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Digital educational technology for care management of diabetes mellitus people's feet.

Santiago, Maria Alice Moreira Torres / Tarcia, Rita Maria Lino / Frederico, Giovana Andrade / Vitorino, Luciano Magalhães / Parisi, Maria Cândida Ribeiro / Gamba, Mônica Antar

Revista brasileira de enfermagem

2021 Volume 74Suppl 5, Issue Suppl 5, Page(s) e20190725

Abstract: Objective: to develop and validate a distance learning course aimed at the pillars of care management of diabetes mellitus people's feet.: Method: a technological production research using Moodle Virtual Learning Environment, based on Andragogy, ... ...

Abstract	Objective: to develop and validate a distance learning course aimed at the pillars of care management of diabetes mellitus people's feet. Method: a technological production research using Moodle Virtual Learning Environment, based on Andragogy, Constructionism and Instructional Design. Content is based on consensus guidelines on diabetic foot. Validation was carried out by distance education, diabetes and/or diabetic foot experts. Results: the course's content is based on diabetic foot guidelines, and is structured in units with didactic material, videos, forums and questionnaires to assess the participants' learning. The judges considered it appropriate to meet nurses' needs in clinical practice. Conclusion: the virtual learning course has been validated, being a promising strategy for training nurses on care management of diabetes mellitus people's feet.
MeSH term(s)	Diabetes Complications ; Diabetes Mellitus/therapy ; Diabetic Foot/therapy ; Education, Continuing ; Education, Distance/methods ; Educational Technology/methods ; Guidelines as Topic ; Humans ; Reproducibility of Results ; Surveys and Questionnaires
Language	Portuguese
Publishing date	2021-03-29
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	731983-6
ISSN	1984-0446 ; 0034-7167
ISSN (online)	1984-0446
ISSN	0034-7167
DOI	10.1590/0034-7167-2019-0725
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Article ; Online: The COVID-19 pandemic and the challenge of using technology for medical education in low and middle income countries.

Cecilio-Fernandes, Dario / Parisi, Maria Cândida Ribeiro / Santos, Thiago M / Sandars, John

MedEdPublish (2016)

2020 Volume 9, Page(s) 74

Abstract: This article was migrated. The article was marked as recommended. The current use of technology for medical education in low and middle income countries (LMIC) during the COVID-19 pandemic is not yet reaching its potential. We provide recommendations for ...

Abstract	This article was migrated. The article was marked as recommended. The current use of technology for medical education in low and middle income countries (LMIC) during the COVID-19 pandemic is not yet reaching its potential. We provide recommendations for LMIC that has focus on a systematic framework that considers both faculty development and developing the skills of students. An enormous challenge for all medical educators, but especially in LMIC, continues to be how to maintain clinical teaching in these extraordinary times.
Language	English
Publishing date	2020-04-23
Publishing country	Scotland
Document type	Journal Article
ISSN	2312-7996
ISSN (online)	2312-7996
DOI	10.15694/mep.2020.000074.1
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Article ; Online: Ambivalence about the selection of cardiovascular risk stratification tools: Evidence in a type 1 diabetes population.

Bovi, Ticiane G / Zantut-Wittmann, Denise Engelbrecht / Parisi, Maria Cândida Ribeiro

Diabetes & metabolic syndrome

2019 Volume 13, Issue 3, Page(s) 2322–2327

Abstract: Background: Cardiovascular disease (CVD) is one of the leading causes of death among people with diabetes, however, despite the increasing incidence of CVD, there are few tools for evaluating Cardiovascular Risk (CVR) in the population of patients with ... ...

Abstract	Background: Cardiovascular disease (CVD) is one of the leading causes of death among people with diabetes, however, despite the increasing incidence of CVD, there are few tools for evaluating Cardiovascular Risk (CVR) in the population of patients with Type 1 Diabetes (T1D), with the existing ones diverging in the stratification of risk and in the suggestions for therapeutic conduct. Methods: A cross-sectional study was carried out with 104 participants diagnosed with T1D, aged 18-40, attending specialized services. The Steno Type 1 Risk Engine and the Cardiovascular Risk Stratification Calculator (CRSC) were used to assess the risk of a cardiovascular event over a 10-year period. Findings: Of the total sample selected, 62% were female, with a median age of 32 years (IQ 24; 43). There was a large difference between the stratification of CVR between the calculators, and 65.82% of the patients classified as low risk for CVD according to the Steno were identified as intermediate (30, 38.00%) and high risk (35.44%) by the CRSC. The analysis also highlighted a great difference in eligibility for statin use according to the risk stratification of the tools. Conclusion: The CRSC and Steno tools evaluated and stratified the CVR of the same population with T1D, with there being divergence of the results. It was found that the CRSC tool classified the majority of the sample as high risk. Due to this result, the eligibility to use statins, which is one of the applications of these tools, showed great differences, with the Steno tool presenting less aggressive provisions regarding the prescription of statins in patients with type 1 DM.
MeSH term(s)	Adolescent ; Adult ; Biomarkers/analysis ; Brazil/epidemiology ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/etiology ; Cross-Sectional Studies ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/epidemiology ; Female ; Follow-Up Studies ; Guideline Adherence ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Male ; Practice Guidelines as Topic/standards ; Prognosis ; Risk Assessment/methods ; Risk Factors ; Young Adult
Chemical Substances	Biomarkers ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
Language	English
Publishing date	2019-05-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2273766-2
ISSN	1878-0334 ; 1871-4021
ISSN (online)	1878-0334
ISSN	1871-4021
DOI	10.1016/j.dsx.2019.05.024
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Article ; Online: Full Diabetic Foot Ulcer Healing and Pain Relief Based on Platelet-Rich-Plasma gel Formulation Treatment and the Involved Pathways.

Leme, Krissia Caroline / Neri, Guilherme Martins / Biscaro, Gabriel Gaspar / Bulgareli, Andreia Afaz / Duran, Nelson / Parisi, Maria Candida Ribeiro / Luzo, Ângela Cristina Malheiros

The international journal of lower extremity wounds

2022 , Page(s) 15347346221109758

Abstract: Diabetic foot ulcer is a severe Diabetic Mellitus-associated complication. It is induced by poor glycemic control, which leads to peripheral neuropathy and vascular diseases. Platelet-rich plasma could be beneficial for healing processes due to its ... ...

Abstract	Diabetic foot ulcer is a severe Diabetic Mellitus-associated complication. It is induced by poor glycemic control, which leads to peripheral neuropathy and vascular diseases. Platelet-rich plasma could be beneficial for healing processes due to its active biomolecules that promotes immunomodulation, angiogenesis, cell proliferation and analgesia.
Language	English
Publishing date	2022-07-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171119-7
ISSN	1552-6941 ; 1534-7346
ISSN (online)	1552-6941
ISSN	1534-7346
DOI	10.1177/15347346221109758
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Zs.A 6003: Show issues

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Article ; Online: Influence of thyroid hormone in the expression of the marker pro-apoptosis BID, in spite of the predominance of anti-apoptosis activation in intratiroidal lymphocytic infiltration in Hashimoto's thyroiditis.

Vasconcelos, Jessica Castro de / Siqueira, Icleia Barreto de / Maia, Frederico Fernandes Ribeiro / Parisi, Maria Cândida Ribeiro / Zantut-Wittmann, Denise Engelbrecht

Molecular and cellular endocrinology

2021 Volume 537, Page(s) 111421

Abstract: Cell destruction in Hashimoto's thyroiditis (HT) involves autoantibodies and cytotoxic T lymphocytes. Thyrocytes maintenance occurs by pro-apoptotic, anti-apoptotic and cell proliferation balance.: Objectives: To characterize factors related to the ... ...

Abstract	Cell destruction in Hashimoto's thyroiditis (HT) involves autoantibodies and cytotoxic T lymphocytes. Thyrocytes maintenance occurs by pro-apoptotic, anti-apoptotic and cell proliferation balance. Objectives: To characterize factors related to the mechanisms of apoptosis and cell proliferation in thyroid cells and intrathyroid lymphocytic infiltrate in HT. Methods: We assessed lymphocytic infiltrate and thyroid cells from HT and normal thyroid by immunohistochemical analysis of cell proliferation (Ki-67), antiproliferation (p27Kip1), pro-apoptosis (Fas, Fas-ligand, BID) and anti-apoptosis (MCL-1, BCL2) markers. Results: Lymphocytic infiltrate presented BCL2 and MCL-1 higher expression, Ki-67 and p27kip1 balance. Thyrocytes exhibited Fas and FasL balance, higher BID expression; MCL-1, BCL-2, Ki-67 similar to the normal thyroid. T4 and higher lymphocytes BID expression were associated. Conclusions: In lymphocytic infiltrate predominated anti-apoptosis in relation to pro-apoptosis except for BID. Thyrocytes presented pro-apoptosis and anti-apoptosis balance and cell proliferation similar to normal thyroid. T4-associated BID expression in HT lymphocytes suggests the influence of thyroid hormone as a signal to up-regulate the BID pro-apoptotic protein and thus increase lymphocytic apoptosis rates.
MeSH term(s)	Adult ; Aged ; Apoptosis/drug effects ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Biomarkers/metabolism ; Cell Proliferation/drug effects ; Female ; Hashimoto Disease/immunology ; Hashimoto Disease/pathology ; Hashimoto Disease/physiopathology ; Humans ; Ki-67 Antigen/metabolism ; Lymphocytes/drug effects ; Lymphocytes/immunology ; Middle Aged ; Organ Size/drug effects ; Thyroid Hormones/pharmacology ; Young Adult
Chemical Substances	BH3 Interacting Domain Death Agonist Protein ; Biomarkers ; Ki-67 Antigen ; Thyroid Hormones
Language	English
Publishing date	2021-08-10
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	187438-x
ISSN	1872-8057 ; 0303-7207
ISSN (online)	1872-8057
ISSN	0303-7207
DOI	10.1016/j.mce.2021.111421
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Zs.A 1127: Show issues

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Article: Influence of thyroid hormone in the expression of the marker pro-apoptosis BID, in spite of the predominance of anti-apoptosis activation in intratiroidal lymphocytic infiltration in Hashimoto’s thyroiditis

Vasconcelos, Jessica Castro de / Siqueira, Icleia Barreto de / Maia, Frederico Fernandes Ribeiro / Parisi, Maria Cândida Ribeiro / Zantut-Wittmann, Denise Engelbrecht

Molecular and cellular endocrinology. 2021 Nov. 01, v. 537

2021

Abstract: Cell destruction in Hashimoto's thyroiditis (HT) involves autoantibodies and cytotoxic T lymphocytes. Thyrocytes maintenance occurs by pro-apoptotic, anti-apoptotic and cell proliferation balance.To characterize factors related to the mechanisms of ... ...

Abstract	Cell destruction in Hashimoto's thyroiditis (HT) involves autoantibodies and cytotoxic T lymphocytes. Thyrocytes maintenance occurs by pro-apoptotic, anti-apoptotic and cell proliferation balance.To characterize factors related to the mechanisms of apoptosis and cell proliferation in thyroid cells and intrathyroid lymphocytic infiltrate in HT.We assessed lymphocytic infiltrate and thyroid cells from HT and normal thyroid by immunohistochemical analysis of cell proliferation (Ki-67), antiproliferation (p27Kip1), pro-apoptosis (Fas, Fas-ligand, BID) and anti-apoptosis (MCL-1, BCL2) markers.Lymphocytic infiltrate presented BCL2 and MCL-1 higher expression, Ki-67 and p27kip1 balance. Thyrocytes exhibited Fas and FasL balance, higher BID expression; MCL-1, BCL-2, Ki-67 similar to the normal thyroid. T4 and higher lymphocytes BID expression were associated.In lymphocytic infiltrate predominated anti-apoptosis in relation to pro-apoptosis except for BID. Thyrocytes presented pro-apoptosis and anti-apoptosis balance and cell proliferation similar to normal thyroid. T4-associated BID expression in HT lymphocytes suggests the influence of thyroid hormone as a signal to up-regulate the BID pro-apoptotic protein and thus increase lymphocytic apoptosis rates.
Keywords	apoptosis ; autoantibodies ; cell proliferation ; cytotoxicity ; immunohistochemistry ; pro-apoptotic proteins ; thyroid hormones
Language	English
Dates of publication	2021-1101
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	187438-x
ISSN	1872-8057 ; 0303-7207
ISSN (online)	1872-8057
ISSN	0303-7207
DOI	10.1016/j.mce.2021.111421
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: The challenges and benefits of online teaching about diabetes during the COVID-19 pandemic.

Parisi, Maria Cândida Ribeiro / Frutuoso, Letícia / Benevides, Saulo Saad Nogueira / Barreira, Nadia Hellmeister Morali / Silva, Juliany Lino Gomes / Pereira, Monica Corso / Cecilio-Fernandes, Dario

Diabetes & metabolic syndrome

2020 Volume 14, Issue 4, Page(s) 575–576

MeSH term(s)	Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/virology ; Education, Distance/methods ; Global Health/education ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Teaching
Keywords	covid19
Language	English
Publishing date	2020-05-11
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2273766-2
ISSN	1878-0334 ; 1871-4021
ISSN (online)	1878-0334
ISSN	1871-4021
DOI	10.1016/j.dsx.2020.04.043
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