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Book ; Online: Autonomous Dimension Reduction by Flattening Deformation of Data Manifold under an Intrinsic Deforming Field

Zhuang, Xiaodong

2021

Abstract: A new dimension reduction (DR) method for data sets is proposed by autonomous deforming of data manifolds. The deformation is guided by the proposed deforming vector field, which is defined by two kinds of virtual interactions between data points. The ... ...

Abstract	A new dimension reduction (DR) method for data sets is proposed by autonomous deforming of data manifolds. The deformation is guided by the proposed deforming vector field, which is defined by two kinds of virtual interactions between data points. The flattening of data manifold is achieved as an emergent behavior under the elastic and repelling interactions between data points, meanwhile the topological structure of the manifold is preserved. To overcome the uneven sampling (or "short-cut edge") problem, the soft neighborhood is proposed, in which the neighbor degree is defined and adaptive interactions between neighbor points is implemented. The proposed method provides a novel geometric viewpoint on dimension reduction. Experimental results prove the effectiveness of the proposed method in dimension reduction, and implicit feature of data sets may also be revealed. Comment: 18 pages, 23 figures
Keywords	Computer Science - Machine Learning ; Computer Science - Computer Vision and Pattern Recognition
Publishing date	2021-10-21
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Organic-moiety-engineering on copper surface for carbon dioxide reduction.

Lu, Chenbao / Su, Yuezeng / Zhu, Jinhui / Sun, Jie / Zhuang, Xiaodong

Chemical communications (Cambridge, England)

2023 Volume 59, Issue 45, Page(s) 6827–6836

Abstract: Electrochemical conversion of carbon dioxide ( ... ...

Abstract	Electrochemical conversion of carbon dioxide (CO
Language	English
Publishing date	2023-06-01
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d3cc01049j
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Research on distribution network fault processing technology based on knowledge of graph

Qiang Li / Feng Zhao / Li Zhuang / Jiangwen Su / Xiaodong Zhang

PLoS ONE, Vol 18, Iss

2023 Volume 12

Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Near-infrared Light-Induced Polymerizations: Mechanisms and Applications.

Qiu, Feng / Gong, Jiao / Tong, Gangsheng / Han, Sheng / Zhuang, Xiaodong / Zhu, Xinyuan

ChemPlusChem

2024 , Page(s) e202300782

Abstract: Photopolymerizations have garnered significant attention in polymer science due to their low polymerization temperature, high production efficiency, environmental friendliness, and spatial controllability. Despite these merits, the poor penetration and ... ...

Abstract	Photopolymerizations have garnered significant attention in polymer science due to their low polymerization temperature, high production efficiency, environmental friendliness, and spatial controllability. Despite these merits, the poor penetration and severe chemical damage from ultraviolet/visible (UV/Vis) light resources pose significant barriers to their success in conventional photopolymerizations. A recent breakthrough involving the utilization of near-infrared (NIR) laser with long wavelength has been exploited for diverse applications. With the combination of a NIR photosensitizer (PS), NIR-induced photopolymerizations have been successfully developed to alleviate the challenges in conventional methods. The enhancement of penetration depth and safety of NIR-induced photopolymerizations can contribute significantly to improving the efficiency of polymerization for production of intricate structures across various scales. In this concept, the typical types of PSs and polymerization mechanisms (PMs) within the NIR-induced photopolymerization systems have been classified in detail. Additionally, the applications of various polymers achieved by NIR-induced photopolymerizations are summarized. Furthermore, research directions and future challenges of this field are also discussed comprehensively.
Language	English
Publishing date	2024-02-12
Publishing country	Germany
Document type	Journal Article ; Review
ISSN	2192-6506
ISSN (online)	2192-6506
DOI	10.1002/cplu.202300782
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Low-Cost and Lithium-Free Hole Transport Layer for Efficient and Stable Normal Perovskite Solar Cells.

Tzoganakis, Nikolaos / Tsikritzis, Dimitris / Chatzimanolis, Konstantinos / Zhuang, Xiaodong / Kymakis, Emmanuel

Nanomaterials (Basel, Switzerland)

2023 Volume 13, Issue 5

Abstract: The most widely used material as a hole-transport layer (HTL) for effective normal perovskite solar cells (PSCs) is still 2,2',7,7'-Tetrakis[N, N-di(4-methoxyphenyl)amino]-9,9'-spirobifluorene (Spiro-OMeTAD), which requires heavy doping with the ... ...

Abstract	The most widely used material as a hole-transport layer (HTL) for effective normal perovskite solar cells (PSCs) is still 2,2',7,7'-Tetrakis[N, N-di(4-methoxyphenyl)amino]-9,9'-spirobifluorene (Spiro-OMeTAD), which requires heavy doping with the hydroscopic Lithium bis(trifluoromethanesulfonyl)imide (Li-ΤFSI). However, the long-term stability and performance of PCSs are frequently hampered by the residual insoluble dopants in the HTL, Li
Language	English
Publishing date	2023-02-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano13050883
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Article: Machine learning-based identification of novel hub genes associated with oxidative stress in lupus nephritis: implications for diagnosis and therapeutic targets.

Zeng, Huiqiong / Zhuang, Yu / Yan, Xiaodong / He, Xiaoyan / Qiu, Qianwen / Liu, Wei / Zhang, Ye

Lupus science & medicine

2024 Volume 11, Issue 1

Abstract: Background: Lupus nephritis (LN) is a complication of SLE characterised by immune dysfunction and oxidative stress (OS). Limited options exist for LN. We aimed to identify LN-related OS, highlighting the need for non-invasive diagnostic and therapeutic ... ...

Abstract	Background: Lupus nephritis (LN) is a complication of SLE characterised by immune dysfunction and oxidative stress (OS). Limited options exist for LN. We aimed to identify LN-related OS, highlighting the need for non-invasive diagnostic and therapeutic approaches. Methods: LN-differentially expressed genes (DEGs) were extracted from Gene Expression Omnibus datasets (GSE32591, GSE112943 and GSE104948) and Molecular Signatures Database for OS-associated DEGs (OSEGs). Functional enrichment analysis was performed for OSEGs related to LN. Weighted gene co-expression network analysis identified hub genes related to OS-LN. These hub OSEGs were refined as biomarker candidates via least absolute shrinkage and selection operator. The predictive value was validated using receiver operating characteristic (ROC) curves and nomogram for LN prognosis. We evaluated LN immune cell infiltration using single-sample gene set enrichment analysis and CIBERSORT. Additionally, gene set enrichment analysis explored the functional enrichment of hub OSEGs in LN. Results: The study identified four hub genes, namely Conclusion: These findings contribute to advancing our understanding of the complex interplay between OS, immune dysregulation and molecular pathways in LN, laying a foundation for the identification of potential diagnostic biomarkers and therapeutic targets.
MeSH term(s)	Humans ; Lupus Nephritis/diagnosis ; Lupus Nephritis/genetics ; Phosphatidylinositol 3-Kinases ; Lupus Erythematosus, Systemic ; Oxidative Stress/genetics ; Machine Learning ; DNA Helicases ; RNA Helicases ; Multifunctional Enzymes
Chemical Substances	Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; SETX protein, human (EC 3.6.1.-) ; DNA Helicases (EC 3.6.4.-) ; RNA Helicases (EC 3.6.4.13) ; Multifunctional Enzymes
Language	English
Publishing date	2024-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2779620-6
ISSN	2053-8790
ISSN	2053-8790
DOI	10.1136/lupus-2023-001126
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Article ; Online: Epitaxial Growth of Two-Dimensional Nonlayered AuCrS

Wang, Mengjia / Chen, DeChao / Li, Zheng / Wang, Ziqian / Huang, Senhe / Hai, Pengqi / Tan, Yongwen / Zhuang, Xiaodong / Liu, Pan

Nano letters

2024 Volume 24, Issue 7, Page(s) 2308–2314

Abstract: Two-dimensional (2D) nonlayered transition metal dichalcogenide (TMD) materials are emergent platforms for various applications from catalysis to quantum devices. However, their limited availability and nonstraightforward synthesis methods hinder our ... ...

Abstract	Two-dimensional (2D) nonlayered transition metal dichalcogenide (TMD) materials are emergent platforms for various applications from catalysis to quantum devices. However, their limited availability and nonstraightforward synthesis methods hinder our understanding of these materials. Here, we present a novel technique for synthesizing 2D nonlayered AuCrS
Language	English
Publishing date	2024-02-07
Publishing country	United States
Document type	Journal Article
ISSN	1530-6992
ISSN (online)	1530-6992
DOI	10.1021/acs.nanolett.3c04672
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Article ; Online: The impact of visit-to-visit heart rate variability on all-cause mortality in atrial fibrillation.

Zhou, Xiaoyan / Yuan, Qinghua / Yuan, Jie / Du, Zhi-Min / Zhuang, Xiaodong / Liao, Xinxue

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

2024 Volume 29, Issue 1, Page(s) e13094

Abstract: Objective: We aimed to investigate the association between visit-to-visit heart rate variability (VVHRV) and all-cause mortality in patients diagnosed with atrial fibrillation (AF). Previous studies have shown a positive correlation between VVHRV and ... ...

Abstract	Objective: We aimed to investigate the association between visit-to-visit heart rate variability (VVHRV) and all-cause mortality in patients diagnosed with atrial fibrillation (AF). Previous studies have shown a positive correlation between VVHRV and several adverse outcomes. However, the relationship between VVHRV and the prognosis of AF remains uncertain. Methods: In our study, we aimed to examine the relationship between VVHRV and mortality rates among 3983 participants with AF, who were part of the AFFIRM study (Atrial Fibrillation Follow-Up Investigation of Rhythm Management). We used the standard deviation of heart rate (HRSD) to measure VVHRV and divided the patients into four groups based on quartiles of HRSD (1st, <5.69; 2nd, 5.69-8.00; 3rd, 8.01-11.01; and 4th, ≥11.02). Our primary endpoint was all-cause death, and we estimated the hazard ratios for mortality using the Cox proportional hazard regressions. Results: Our analysis included 3983 participants from the AFFIRM study and followed for an average of 3.5 years. During this period, 621 participants died from all causes. In multiple-adjustment models, we found that the lowest and highest quartiles of HRSD independently predicted an increased risk of all-cause mortality compared to the other two quartiles, presenting a U-shaped relationship (1st vs 2nd, hazard ratio = 2.28, 95% CI = 1.63-3.20, p < .01; 1st vs. 3rd, hazard ratio = 2.23, 95% CI = 1.60-3.11, p < .01; 4th vs. 2nd, hazard ratio = 1.82, 95% CI = 1.26-2.61, p < .01; and 4th vs. 3rd, hazard ratio = 1.78, 95% CI = 1.25-2.52, p < .01). Conclusion: In patients with AF, we found that both lower VVHRV and higher VVHRV increased the risk of all-cause mortality, indicating a U-shaped curve relationship.
MeSH term(s)	Humans ; Atrial Fibrillation ; Causality ; Electrocardiography ; Heart Rate/physiology ; Prognosis ; Risk Factors ; Mortality
Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	1325530-7
ISSN	1542-474X ; 1082-720X
ISSN (online)	1542-474X
ISSN	1082-720X
DOI	10.1111/anec.13094
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Zs.A 4953: Show issues

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bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
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Article ; Online: The role of circadian clock pathways in viral replication.

Zhuang, Xiaodong / Edgar, Rachel S / McKeating, Jane A

Seminars in immunopathology

2022 Volume 44, Issue 2, Page(s) 175–182

Abstract: The daily oscillations of bi ological and behavioural processes are controlled by the circadian clock circuitry that drives the physiology of the organism and, in particular, the functioning of the immune system in response to infectious agents. ... ...

Abstract	The daily oscillations of bi ological and behavioural processes are controlled by the circadian clock circuitry that drives the physiology of the organism and, in particular, the functioning of the immune system in response to infectious agents. Circadian rhythmicity is known to affect both the pharmacokinetics and pharmacodynamics of pharmacological agents and vaccine-elicited immune responses. A better understanding of the role circadian pathways play in the regulation of virus replication will impact our clinical management of these diseases. This review summarises the experimental and clinical evidence on the interplay between different viral pathogens and our biological clocks, emphasising the importance of continuing research on the role played by the biological clock in virus-host organism interaction.
MeSH term(s)	Circadian Clocks/physiology ; Circadian Rhythm/physiology ; Humans ; Virus Replication
Language	English
Publishing date	2022-02-22
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2316828-6
ISSN	1863-2300 ; 1863-2297
ISSN (online)	1863-2300
ISSN	1863-2297
DOI	10.1007/s00281-021-00908-2
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Zs.A 1425: Show issues

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Article ; Online: Simultaneously improving the pore structure and electron conductive network of the anode catalyst layer

Li, Bang / Li, Guangfu / Wan, Qiqi / Yuan, Lei / Liu, Yingying / Li, Longxu / Zhuang, Xiaodong / Zhang, Junliang / Ke, Changchun

RSC advances

2024 Volume 14, Issue 15, Page(s) 10390–10396

Abstract: Proton exchange membrane water electrolysis (PEMWE) is a promising technology for green hydrogen production. However, its large-scale commercial application is limited by its high precious metal loading, because low catalyst loading leads to reduced ... ...

Abstract	Proton exchange membrane water electrolysis (PEMWE) is a promising technology for green hydrogen production. However, its large-scale commercial application is limited by its high precious metal loading, because low catalyst loading leads to reduced electron transport channels and decreased water transportation,
Language	English
Publishing date	2024-04-02
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d4ra00270a
Database	MEDical Literature Analysis and Retrieval System OnLINE

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