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Book ; Online ; E-Book: Hyperacusis and disorders of sound intolerance

Fagelson, Marc / Baguley, David M.

clinical and research perspectives

2018

Abstract: This is a professional resource for audiology practitioners involved in the clinical management of patients who have sound tolerance concerns. The text covers emerging assessment and intervention strategies associated with hyperacusis, disorders of pitch ...

Author's details	Marc Fagelson, PhD, David M. Baguley, BSc, MSc, MBA, PhD
Abstract	This is a professional resource for audiology practitioners involved in the clinical management of patients who have sound tolerance concerns. The text covers emerging assessment and intervention strategies associated with hyperacusis, disorders of pitch perception, and other unusual processing deficits of the auditory system. In order to illustrate the patients' perspectives and experiences with disorders of auditory processing, cases are included throughout.
Keywords	Hyperacusis / diagnosis ; Hyperacusis / therapy ; Tinnitus / diagnosis ; Tinnitus / therapy
Language	English
Size	1 Online-Ressource (xi, 280 Seiten), Illustrationen, Diagramme
Publisher	Plural Publishing Inc
Publishing place	San Diego, CA
Publishing country	United States
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT019942832
ISBN	978-1-944883-29-4 ; 1-944883-29-0
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book: Hyperacusis

Baguley, David M. / Andersson, Gerhard

mechanisms, diagnosis, and therapies

2007

Author's details	David M. Baguley ; Gerhard Andersson
Keywords	Hyperacusis
Language	English
Size	XII, 110 S. : Ill.
Publisher	Plural Publ
Publishing place	San Diego, Calif. u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT015036528
ISBN	1-59756-104-5 ; 978-1-59756-104-4
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2007 A 4354	order for loan	Magazin

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Article ; Online: The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review.

Phillips, Olivia R / Baguley, David M / Pearson, Stephanie E / Akeroyd, Michael A

Journal of cancer survivorship : research and practice

2023 Volume 17, Issue 1, Page(s) 40–58

Abstract: Purpose: To elucidate the long-term impacts of hearing loss, tinnitus and balance in people living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT).: Methods: A literature search was conducted between March and June 2022 ... ...

Abstract	Purpose: To elucidate the long-term impacts of hearing loss, tinnitus and balance in people living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT). Methods: A literature search was conducted between March and June 2022 using PubMed, Web of Science and Google Scholar. Full-text papers in English were included. Articles explored the impacts of hearing loss, tinnitus and balance and discussed them in the context of treatment. If PBCT was used in conjunction with other treatments, the article was included. There were no constraints on age, cancer type, publication date, location, study design or data type. Sixteen studies and two reviews were included. Results: Hearing loss and tinnitus can cause communication difficulties and subsequent social withdrawal. There were deficits in cognition, child development and educational performance. Employment and the ease of everyday life were disrupted by hearing loss and tinnitus, whereas poor balance interfered with walking and increased the risk of falls. Depression and anxiety were related to ototoxicity. Most notable were the differing mindsets experienced by adults LWBC with ototoxicity. There was evidence of inadequate monitoring of ototoxicity by clinicians and a lack of communication between clinicians and patients about ototoxicity as a side effect. Conclusions: Ototoxicity has a negative long-term impact on multiple areas of life for adults and children LWBC. This can compromise their quality of life. Implications for cancer survivors: Increased awareness, monitoring and education surrounding these issues may lead to earlier intervention and better management of ototoxicity, enhancing the quality of life of people LWBC.
MeSH term(s)	Child ; Adult ; Humans ; Antineoplastic Agents/adverse effects ; Cisplatin/adverse effects ; Carboplatin/adverse effects ; Tinnitus/chemically induced ; Quality of Life ; Platinum/therapeutic use ; Ototoxicity/drug therapy ; Ototoxicity/etiology ; Cancer Survivors ; Hearing Loss/chemically induced ; Neoplasms/complications ; Neoplasms/drug therapy
Chemical Substances	Antineoplastic Agents ; Cisplatin (Q20Q21Q62J) ; Carboplatin (BG3F62OND5) ; Platinum (49DFR088MY)
Language	English
Publishing date	2023-01-13
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2388888-X
ISSN	1932-2267 ; 1932-2259
ISSN (online)	1932-2267
ISSN	1932-2259
DOI	10.1007/s11764-022-01314-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An Exploratory Investigation of Pupillometry As a Measure of Tinnitus Intrusiveness on a Test of Auditory Short-Term Memory.

Barrett, Doug J K / Souto, David / Pilling, Michael / Baguley, David M

Ear and hearing

2022 Volume 43, Issue 5, Page(s) 1540–1548

Abstract: Objectives: The purpose of the current study was to investigate the potential of pupillometry to provide an objective measure of competition between tinnitus and external sounds during a test of auditory short-term memory.: Design: Twelve ... ...

Abstract	Objectives: The purpose of the current study was to investigate the potential of pupillometry to provide an objective measure of competition between tinnitus and external sounds during a test of auditory short-term memory. Design: Twelve participants with chronic tinnitus and twelve control participants without tinnitus took part in the study. Pretest sessions used an adaptive method to estimate listeners' frequency discrimination threshold on a test of delayed pitch discrimination for pure tones. Target and probe tones were presented at 72 dB SPL and centered on 750 Hz±2 semitones with an additional jitter of 5 to 20 Hz. Test sessions recorded baseline pupil diameter and task-related pupillary responses (TEPRs) during three blocks of delayed pitch discrimination trials. The difference between target and probe tones was set to the individual's frequency detection threshold for 80% response-accuracy. Listeners with tinnitus also completed the Tinnitus Handicap Inventory (THI). Linear mixed effects procedures were applied to examine changes in baseline pupil diameter and TEPRs associated with group (tinnitus versus control), block (1 to 3) and their interaction. The association between THI scores and maximum TEPRs was assessed using simple linear regression. Results: Patterns of baseline pupil dilation across trials diverged in listeners with tinnitus and controls. For controls, baseline pupil dilation remained constant across blocks. For listeners with tinnitus, baseline pupil dilation increased on blocks 2 and 3 compared with block 1. TEPR amplitudes were also larger in listeners with tinnitus than controls. Linear mixed effects models yielded a significant group by block interaction for baseline pupil diameter and a significant main effect of group on maximum TEPR amplitudes. Regression analyses yielded a significant association between THI scores and TEPR amplitude in listeners with tinnitus. Conclusions: Our data indicate measures of baseline pupil diameter, and TEPRs are sensitive to competition between tinnitus and external sounds during a test of auditory short-term memory. This result suggests pupillometry can provide an objective measure of intrusion in tinnitus. Future research will be required to establish whether our findings generalize to listeners across a full range of tinnitus severity.
MeSH term(s)	Auditory Perception/physiology ; Humans ; Memory, Short-Term ; Pitch Discrimination/physiology ; Pupil/physiology ; Tinnitus
Language	English
Publishing date	2022-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	603093-2
ISSN	1538-4667 ; 0196-0202
ISSN (online)	1538-4667
ISSN	0196-0202
DOI	10.1097/AUD.0000000000001214
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1548: Show issues

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Article: The International Vocabulary of Tinnitus.

Baguley, David M / Caimino, Charlotte / Gilles, Annick / Jacquemin, Laure

Frontiers in neuroscience

2022 Volume 16, Page(s) 887592

Abstract: Tinnitus is a common experience which can have a severe impact on ones quality of life. Whilst there have been reports of historical references to tinnitus, there has not been an international cross-sectional analysis of the vocabulary used for tinnitus. ...

Abstract	Tinnitus is a common experience which can have a severe impact on ones quality of life. Whilst there have been reports of historical references to tinnitus, there has not been an international cross-sectional analysis of the vocabulary used for tinnitus. In this study, with 227 respondents (of which 53.3% experiencing tinnitus themselves), we report such an analysis of 252 words or phrases, from 42 languages and 48 countries. The results indicate that the majority of vocabulary used has a negative connotation (63%), though a small minority are positive (4%). Many words used for tinnitus in different languages are onomatopoeic-thus mimicking aspects of the percept experienced-or describe the sound (in total 42% of the vocabulary). The involvement of the ear is implied in some terminology, though other vocabulary expresses the impact. Participants experiencing tinnitus significantly differed on the codes for their proposed words or phrases (
Language	English
Publishing date	2022-05-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2022.887592
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Looking beyond the audiogram in ototoxicity associated with platinum-based chemotherapy.

Baguley, David M / Prayuenyong, Pattarawadee

Cancer chemotherapy and pharmacology

2019 Volume 85, Issue 2, Page(s) 245–250

Abstract: Introduction: Ototoxicity associated with platinum-based chemotherapy is highly prevalent and can cause detrimental consequences among cancer survivors.: Discussion: In this article, we highlight important aspects of the evaluation of ototoxicity ... ...

Abstract	Introduction: Ototoxicity associated with platinum-based chemotherapy is highly prevalent and can cause detrimental consequences among cancer survivors. Discussion: In this article, we highlight important aspects of the evaluation of ototoxicity with the aim to increase awareness of Oncologists in this regard. Standard pure tone audiometry alone is inadequate for this context. Comprehensive and consistent hearing tests should be implemented in a monitoring and surveillance program. High-frequency audiometry (10-16 kHz) is a sensitive tool in the detection of ototoxic hearing loss at onset. In addition to threshold audiometry, measures of speech comprehension (both in quiet and in noise) can add useful information in the evaluation of hearing in real-life situations. Not only hearing loss, but also tinnitus and imbalance are common in patients who receive platinum-based chemotherapy, and can cause debilitating effects upon quality of life in this population. Moreover, self-report measures associated with cochlear and vestibular handicaps can provide valuable information regarding the impact of ototoxicity. Conclusions: It is vital to build awareness about the variety and impact of the symptoms of ototoxicity. Comprehensive evaluation of hearing status along with self-reported impact of the cochlear and vestibular handicap should be implemented in a monitoring and surveillance program for appropriate investigation and management.
MeSH term(s)	Antineoplastic Agents/adverse effects ; Hearing/drug effects ; Hearing Loss/chemically induced ; Humans ; Organoplatinum Compounds/adverse effects ; Ototoxicity/etiology
Chemical Substances	Antineoplastic Agents ; Organoplatinum Compounds
Language	English
Publishing date	2019-12-21
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	6820-2
ISSN	1432-0843 ; 0344-5704 ; 0943-9404
ISSN (online)	1432-0843
ISSN	0344-5704 ; 0943-9404
DOI	10.1007/s00280-019-04012-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1420: Show issues

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Article ; Online: Readability assessment of self-report hyperacusis questionnaires.

Margol-Gromada, Magdalena / Sereda, Magdalena / Baguley, David M

International journal of audiology

2020 Volume 59, Issue 7, Page(s) 506–512

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Comprehension ; Educational Status ; Health Literacy ; Humans ; Hyperacusis/diagnosis ; Reading ; Surveys and Questionnaires/standards
Language	English
Publishing date	2020-03-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2073098-6
ISSN	1708-8186 ; 1499-2027
ISSN (online)	1708-8186
ISSN	1499-2027
DOI	10.1080/14992027.2020.1723033
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Zs.A 549: Show issues

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Article ; Online: The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study.

Pearson, Stephanie E / Caimino, Charlotte / Shabbir, Maryam / Baguley, David M

Journal of cancer survivorship : research and practice

2021 Volume 16, Issue 5, Page(s) 976–987

Abstract: Purpose: This study aimed to explore the burden of inner ear damage (ototoxicity) on adults living with and beyond cancer treated with chemotherapy and the impact on their quality of life (QoL). Furthermore, this study aimed to explore patient ... ...

Abstract	Purpose: This study aimed to explore the burden of inner ear damage (ototoxicity) on adults living with and beyond cancer treated with chemotherapy and the impact on their quality of life (QoL). Furthermore, this study aimed to explore patient awareness surrounding chemotherapy-induced inner ear damage, known as ototoxicity, and assess what support they had been offered. Methods: Participants were adults who had undergone chemotherapy, recruited from cancer clinics, charities and social media. Using semi-structured interviews and fieldnotes, an inductive thematic analysis was used to develop key themes surrounding this topic. Results: Twenty participants from the UK were interviewed. Two key themes were developed from the thematic analysis, cancer-related QoL and ototoxicity-related QoL, with each one including 5 subthemes. Subthemes consisted of impact of ototoxicity, hearing, tinnitus, clinical experience, audiological assessments, and impact of treatment, cancer and chemotherapy, other toxicities, information and patient reflections. Conclusions: Ototoxicity can have a negative impact on QoL, specifically on social life and the fear of hearing loss and/or tinnitus worsening. There are opportunities for increased awareness by patients and clinicians, including improved information sources, and hearing monitoring not only for those undergoing platinum-based chemotherapy but many others surviving after treatment for cancer. Implications for cancer survivors: Better monitoring of hearing and information about ototoxicity during chemotherapy could potentially reduce the fear of the symptoms of ototoxicity worsening. Furthermore, hearing monitoring would facilitate the detection of hearing loss at early stages of survivorship, which would facilitate earlier access to clinical interventions and longer term counselling.
MeSH term(s)	Adult ; Antineoplastic Agents/adverse effects ; Cancer Survivors ; Ear, Inner ; Hearing Loss/chemically induced ; Humans ; Neoplasms/drug therapy ; Ototoxicity ; Quality of Life ; Tinnitus/chemically induced
Chemical Substances	Antineoplastic Agents
Language	English
Publishing date	2021-08-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2388888-X
ISSN	1932-2267 ; 1932-2259
ISSN (online)	1932-2267
ISSN	1932-2259
DOI	10.1007/s11764-021-01089-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Preferential Cochleotoxicity of Cisplatin.

Prayuenyong, Pattarawadee / Baguley, David M / Kros, Corné J / Steyger, Peter S

Frontiers in neuroscience

2021 Volume 15, Page(s) 695268

Abstract: Cisplatin-induced ototoxicity in humans is more predominant in the cochlea than in the vestibule. Neither definite nor substantial vestibular dysfunction after cisplatin treatment has been consistently reported in the current literature. Inner ear hair ... ...

Abstract	Cisplatin-induced ototoxicity in humans is more predominant in the cochlea than in the vestibule. Neither definite nor substantial vestibular dysfunction after cisplatin treatment has been consistently reported in the current literature. Inner ear hair cells seem to have intrinsic characteristics that make them susceptible to direct exposure to cisplatin. The existing literature suggests, however, that cisplatin might have different patterns of drug trafficking across the blood-labyrinth-barrier, or different degrees of cisplatin uptake to the hair cells in the cochlear and vestibular compartments. This review proposes an explanation for the preferential cochleotoxicity of cisplatin based on current evidence as well as the anatomy and physiology of the inner ear. The endocochlear potential, generated by the stria vascularis, acting as the driving force for hair cell mechanoelectrical transduction might also augment cisplatin entry into cochlear hair cells. Better understanding of the stria vascularis might shed new light on cochleotoxic mechanisms and inform the development of otoprotective interventions to moderate cisplatin associated ototoxicity.
Language	English
Publishing date	2021-07-26
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2021.695268
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Article: Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.

Prayuenyong, Pattarawadee / Kasbekar, Anand V / Baguley, David M

Frontiers in public health

2020 Volume 8, Page(s) 252

Abstract: At this time of the COVID-19 pandemic, potentially effective treatments are currently under urgent investigation. Benefits of chloroquine and hydroxychloroquine for the treatment of COVID-19 infection have been proposed and clinical trials are underway. ... ...

Abstract	At this time of the COVID-19 pandemic, potentially effective treatments are currently under urgent investigation. Benefits of chloroquine and hydroxychloroquine for the treatment of COVID-19 infection have been proposed and clinical trials are underway. Chloroquine and hydroxychloroquine, typically used for the treatment of malaria and autoimmune diseases, have been considered for off-label use in several countries. In the literature, there are reports of ototoxic effects of the drugs causing damage to the inner ear structures, which then result in hearing loss, tinnitus, and/or imbalance. This mini-review represents a summary of the findings from a systematic search regarding ototoxicity of chloroquine and hydroxychloroquine in the published literature. The characteristics of sensorineural hearing loss and/or tinnitus after chloroquine or hydroxychloroquine treatment can be temporary but reports of persistent auditory and vestibular dysfunction exist. These are not frequent, but the impact can be substantial. Additionally, abnormal cochleovestibular development in the newborn was also reported after chloroquine treatment in pregnant women. The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater. There are potential implications from this review for survivors of COVID-19 treated with chloroquine or hydroxychloroquine. Patient reports of hearing loss, tinnitus, or imbalance should be noted. Those with troublesome hearing loss, tinnitus and/or imbalance are encouraged to be referred for hearing evaluation and interventions once they are stable. Clinical trials of chloroquine or hydroxychloroquine should also consider including audiological monitoring in the protocol.
MeSH term(s)	Antimalarials/administration & dosage ; Antiviral Agents/administration & dosage ; COVID-19/drug therapy ; Chloroquine/administration & dosage ; Emergencies ; Hearing Loss/etiology ; Humans ; Hydroxychloroquine/administration & dosage ; Ototoxicity/complications ; Public Health ; SARS-CoV-2 ; Tinnitus/etiology
Chemical Substances	Antimalarials ; Antiviral Agents ; Hydroxychloroquine (4QWG6N8QKH) ; Chloroquine (886U3H6UFF)
Keywords	covid19
Language	English
Publishing date	2020-05-29
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2711781-9
ISSN	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2020.00252
Database	MEDical Literature Analysis and Retrieval System OnLINE

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