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Article: [Rezension von: Davis, S. J., ..., Job creation and destruction]

Picot, W. Garnett / Davis, S. J

The review of income and wealth : journal of the International Association for Research in Income and Wealth 43 ,2, S. 253-260

1997

Author's details	Garnett Picot
Keywords	40;49
Language	English
Publisher	Wiley-Blackwell
Publishing place	Oxford [u.a.]
Document type	Article
ZDB-ID	218541-6 ; 2051176-0
ISSN	1475-4991 ; 0034-6586
ISSN (online)	1475-4991
ISSN	0034-6586
Database	ECONomics Information System

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Article ; Online: Finding the Hidden Professional Culture of Mental Health Nursing-Spiritual Care for Individuals with a Co-morbid Life-Limiting Illness.

Picot, Sharon / Harrington, Ann / Fuller, Jeffrey

Issues in mental health nursing

2023 Volume 44, Issue 10, Page(s) 951–959

Abstract: People with severe mental illness are dying up to thirty years earlier than the general population. The limited literature on their experience of dying indicates that they often suffer from inequities in their access to healthcare services, and further, ... ...

Abstract	People with severe mental illness are dying up to thirty years earlier than the general population. The limited literature on their experience of dying indicates that they often suffer from inequities in their access to healthcare services, and further, what care they do receive is frequently poor. Living with both a mental illness and facing death can engender spiritual concerns and dying at a younger age is a risk factor for spiritual despair. Hence, addressing spiritual concerns can be an important dimension of mental health nursing care. The aim of this ethnographic study of 11 senior and experienced mental health nurses was to determine if the culture of the mental health service impacted their spiritual care for those patients who were facing death. The data highlighted that the nurses felt comfortable in providing spiritual care when the person was suffering from psychosis. Yet, the results also revealed that nurses felt disempowered by the dominance of the biomedical culture, in which they felt unable to articulate their care. However, it was identified that their spiritual care was inherent within the professional values, knowledge, and skills of mental health nursing and framed through their therapeutic relationships. Therefore, strategies need to be used by the organization to assist nurses to reclaim their power and assist the mental health service to further develop and engage in spiritual care practices.
MeSH term(s)	Humans ; Psychiatric Nursing ; Spirituality ; Psychotic Disorders ; Comorbidity ; Spiritual Therapies
Language	English
Publishing date	2023-11-15
Publishing country	England
Document type	Journal Article
ZDB-ID	603180-8
ISSN	1096-4673 ; 0161-2840
ISSN (online)	1096-4673
ISSN	0161-2840
DOI	10.1080/01612840.2023.2246064
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Article ; Online: Microbial interactions in theory and practice: when are measurements compatible with models?

Picot, Aurore / Shibasaki, Shota / Meacock, Oliver J / Mitri, Sara

Current opinion in microbiology

2023 Volume 75, Page(s) 102354

Abstract: Most predictive models of ecosystem dynamics are based on interactions between organisms: their influence on each other's growth and death. We review here how theoretical approaches are used to extract interaction measurements from experimental data in ... ...

Abstract	Most predictive models of ecosystem dynamics are based on interactions between organisms: their influence on each other's growth and death. We review here how theoretical approaches are used to extract interaction measurements from experimental data in microbiology, particularly focusing on the generalised Lotka-Volterra (gLV) framework. Though widely used, we argue that the gLV model should be avoided for estimating interactions in batch culture - the most common, simplest and cheapest in vitro approach to culturing microbes. Fortunately, alternative approaches offer a way out of this conundrum. Firstly, on the experimental side, alternatives such as the serial-transfer and chemostat systems more closely match the theoretical assumptions of the gLV model. Secondly, on the theoretical side, explicit organism-environment interaction models can be used to study the dynamics of batch-culture systems. We hope that our recommendations will increase the tractability of microbial model systems for experimentalists and theoreticians alike.
MeSH term(s)	Ecosystem ; Models, Theoretical ; Models, Biological ; Microbial Interactions
Language	English
Publishing date	2023-07-06
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	1418474-6
ISSN	1879-0364 ; 1369-5274
ISSN (online)	1879-0364
ISSN	1369-5274
DOI	10.1016/j.mib.2023.102354
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Zs.A 5514: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Cardiac magnetic resonance ventricular parameters correlate with cardiopulmonary fitness in patients with functional single ventricle.

Bredy, Charlene / Werner, Oscar / Helena, Huguet / Picot, Marie-Christine / Amedro, Pascal / Adda, Jerome

The international journal of cardiovascular imaging

2024

Abstract: Owing to advances in medical and surgical fields, patients with single ventricle (SV) have a greatly improved life expectancy. However, progressive functional deterioration is observed over time, with a decrease in cardiopulmonary fitness. This study ... ...

Abstract	Owing to advances in medical and surgical fields, patients with single ventricle (SV) have a greatly improved life expectancy. However, progressive functional deterioration is observed over time, with a decrease in cardiopulmonary fitness. This study aimed to identify, in patients with SV, the association between cardiac magnetic resonance imaging (CMR) parameters and change in cardiopulmonary fitness assessed by cardiopulmonary exercise test (CPET), and if certain thresholds could anticipate a decline in aerobic fitness. Patients with an SV physiology were retrospectively screened from 2011 and 2021 in a single-centre observational study. We evaluated (1) the correlation between baseline CMR and CPET parameters, (2) the association between baseline CMR results and change in peak oxygen uptake (peak VO
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-024-03072-4
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Article ; Online: The 26RFa (QRFP)/GPR103 neuropeptidergic system: A key regulator of energy and glucose metabolism.

Devère, Mélodie / Takhlidjt, Saloua / Prévost, Gaëtan / Chartrel, Nicolas / Leprince, Jérôme / Picot, Marie

Neuroendocrinology

2024

Abstract: Background: Obesity and type 2 diabetes are strongly associated pathologies, currently considered as a worldwide epidemic problem. Understanding the mechanisms that drive the development of these diseases would enable to develop new therapeutic ... ...

Abstract	Background: Obesity and type 2 diabetes are strongly associated pathologies, currently considered as a worldwide epidemic problem. Understanding the mechanisms that drive the development of these diseases would enable to develop new therapeutic strategies for their prevention and treatment. Particularly, the role of the brain in the energy and glucose homeostasis has been studied for two decades. In specific, the hypothalamus contains well-identified neural networks regulating appetite and potentially also glucose homeostasis. A new concept has thus emerged, suggesting that obesity and diabetes could be due to a dysfunction of the same, still poorly understood, neural networks. Summary: The neuropeptide 26RFa (also termed QRFP) belongs to the family of RFamide regulatory peptides and has been identified as the endogenous ligand of the human G protein-coupled receptor GPR103 (QRFPR). The primary structure of 26RFa is strongly conserved during vertebrate evolution, suggesting its crucial roles in the control of vital functions. Indeed, the 26RFa/GPR103 peptidergic system is reported to be involved in the control of various neuroendocrine functions, notably the control of energy metabolism in which it plays an important role, both centrally and peripherally, since 26RFa regulates feeding behavior, thermogenesis and lipogenesis. Moreover, 26RFa is reported to control glucose homeostasis both peripherally, where it acts as an incretin, and centrally, where the 26RFa/GPR103 system relays insulin signaling in the brain to control glucose metabolism. Key messages: This review gives a comprehensive overview of the role of the 26RFa/GPR103 system as a key player in the control of energy and glucose metabolism. In pathophysiological context, this neuropeptidergic system represents a prime therapeutic target whose mechanisms are highly relevant to decipher.
Language	English
Publishing date	2024-04-10
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	123303-8
ISSN	1423-0194 ; 0028-3835
ISSN (online)	1423-0194
ISSN	0028-3835
DOI	10.1159/000538629
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Article: Une chapelle de Iéproserie oubliée: Saint-Lazare d'Herbet, à Clermont-Ferrand.

Picot, Johan

Revue de la Societe francaise d'histoire des hopitaux

2014 , Issue 152, Page(s) 17–23

Title translation	The forgotten leper colony: Saint Lazare at Clermont-Ferrand.
MeSH term(s)	Catholicism ; France ; History, Ancient ; History, Medieval ; Hospital Design and Construction/history ; Humans ; Leper Colonies/history ; Leprosy/history
Language	French
Publishing date	2014-11
Publishing country	France
Document type	Historical Article ; Journal Article
ZDB-ID	1217183-9
ISSN	1255-250X
ISSN	1255-250X
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Zs.A 4653: Show issues

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Article ; Online: Neurodevelopmental outcomes after prenatal exposure to lamotrigine monotherapy in women with epilepsy: a systematic review and meta-analysis.

Peron, Audrey / Picot, Cyndie / Jurek, Lucie / Nourredine, Mikaïl / Ripoche, Emmanuelle / Ajiji, Priscilla / Cucherat, Michel / Cottin, Judith

BMC pregnancy and childbirth

2024 Volume 24, Issue 1, Page(s) 103

Abstract: Background: Lamotrigine has become one of the most commonly prescribed antiseizure medications (ASM) in epileptic women during pregnancy and therefore requires regular updates regarding its safety. The aim of this study was to estimate the association ... ...

Abstract	Background: Lamotrigine has become one of the most commonly prescribed antiseizure medications (ASM) in epileptic women during pregnancy and therefore requires regular updates regarding its safety. The aim of this study was to estimate the association between in utero exposure to lamotrigine monotherapy and the occurrence of neurodevelopmental outcomes. Methods: All comparative studies assessing the occurrence of neurodevelopmental outcomes after epilepsy-indicated lamotrigine monotherapy exposure during pregnancy were searched. First, references were identified through a snowballing approach, then, through electronic databases (Medline and Embase) from 2015 to June 2022. One investigator evaluated study eligibility and extracted data and a second independent investigator reviewed the meta-analysis (MA). A systematic review and random-effects model approach were performed using a collaborative WEB-based meta-analysis platform (metaPreg.org) with a registered protocol (osf.io/u4gva). Results: Overall, 18 studies were included. For outcomes reported by at least 4 studies, the pooled odds ratios and 95% confidence interval obtained with the number of exposed (N1) and unexposed children (N0) included were: neurodevelopmental disorders as a whole 0.84 [0.66;1.06] (N1 = 5,271; N0 = 22,230); language disorders or delay 1.16 [0.67;2.00] (N1 = 313; N0 = 506); diagnosis or risk of ASD 0.97 [0.61;1.53] (N1 = at least 5,262; N0 = 33,313); diagnosis or risk of ADHD 1.14 [0.75;1.72] (N1 = at least 113; N0 = 11,530) and psychomotor developmental disorders or delay 2.68 [1.29-5.56] (N1 = 163; N0 = 220). The MA of cognitive outcomes included less than 4 studies and retrieved a significant association for infants exposed to lamotrigine younger than 3 years old but not in the older age groups. Conclusion: Prenatal exposure to lamotrigine monotherapy is not found to be statistically associated with neurodevelopmental disorders as a whole, language disorders or delay, diagnosis or risk of ASD and diagnosis or risk of ADHD. However, the MA found an increased risk of psychomotor developmental disorders or delay and cognitive developmental delay in less than 3 years old children. Nevertheless, these findings were based exclusively on observational studies presenting biases and on a limited number of included children. More studies should assess neurodevelopmental outcomes in children prenatally exposed to lamotrigine.
MeSH term(s)	Pregnancy ; Child ; Infant ; Female ; Humans ; Aged ; Child, Preschool ; Lamotrigine/adverse effects ; Prenatal Exposure Delayed Effects/epidemiology ; Prenatal Exposure Delayed Effects/chemically induced ; Anticonvulsants/adverse effects ; Epilepsy/drug therapy ; Vitamins/therapeutic use ; Language Disorders/chemically induced ; Language Disorders/drug therapy
Chemical Substances	Lamotrigine (U3H27498KS) ; Anticonvulsants ; Vitamins
Language	English
Publishing date	2024-02-02
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2059869-5
ISSN	1471-2393 ; 1471-2393
ISSN (online)	1471-2393
ISSN	1471-2393
DOI	10.1186/s12884-023-06242-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Use of proton pump inhibitors during pregnancy: A systematic review and meta-analysis of congenital malformations.

Peron, Audrey / Ripoche, Emmanuelle / Picot, Cyndie / Ajiji, Priscilla / Cucherat, Michel / Cottin, Judith

Reproductive toxicology (Elmsford, N.Y.)

2023 Volume 119, Page(s) 108419

Abstract: Use of proton pump inhibitors (PPI) are common among pregnant women to relieve gastrointestinal symptoms. The number of exposed pregnancies is therefore considerable, and a recent meta-analysis (MA) from 2020 raised concern about their teratogenicity. ... ...

Abstract	Use of proton pump inhibitors (PPI) are common among pregnant women to relieve gastrointestinal symptoms. The number of exposed pregnancies is therefore considerable, and a recent meta-analysis (MA) from 2020 raised concern about their teratogenicity. The aim of the study was to provide a MA of the risk of major congenital malformations (MCM) after PPI exposure during the first trimester of pregnancy. A systematic review and random-effects model approach were performed using a collaborative WEB-based meta-analysis platform (metaPreg.org) with a registered protocol (osf.io/u4gva). The primary outcome was the incidence of overall MCM. The secondary outcomes of interest were specific MCM reported by at least three studies. All comparative studies assessing these outcomes in PPI exposed pregnancies were searched from inception to April 2022. From the 211 initially identified studies, 11 were included in the MA. The pooled odds ratio (OR) for the primary outcome showed no significant results based on 5 618 exposed pregnancies (OR 1.10, 95% CI [0.95;1.26]; I²=0%). Similarly, no result was significant for the secondary outcomes. The total exposed sample size ranged from 3 161-5 085; OR ranged between 0.60 and 1.92; heterogeneity was between 0% and 23%. Based on the results of the present MA, first trimester PPI exposure was not associated with a significantly increased risk of overall or specific MCM. However, this MA included only observational studies which are prone to bias and there were insufficient data to evaluate PPI at a substance level. Future studies are needed to address this concern.
MeSH term(s)	Pregnancy ; Humans ; Female ; Proton Pump Inhibitors/adverse effects ; Pregnancy Trimester, First ; Teratogenesis
Chemical Substances	Proton Pump Inhibitors
Language	English
Publishing date	2023-06-02
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	639342-1
ISSN	1873-1708 ; 0890-6238
ISSN (online)	1873-1708
ISSN	0890-6238
DOI	10.1016/j.reprotox.2023.108419
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Article ; Online: Changes in mothers' and fathers' stress level, mental health and coping strategies during the 3 years following ASD diagnosis.

Rattaz, Cécile / Loubersac, Julie / Michelon, Cécile / Picot, Marie-Christine / Baghdadli, Amaria

Research in developmental disabilities

2023 Volume 137, Page(s) 104497

Abstract: Background: ASD in a child affects parental mental health, with elevated levels of stress, anxiety and depression reported in parents.: Method: In this study, we examined mothers' and fathers' stress, anxiety and depression, as well as their coping ... ...

Abstract	Background: ASD in a child affects parental mental health, with elevated levels of stress, anxiety and depression reported in parents. Method: In this study, we examined mothers' and fathers' stress, anxiety and depression, as well as their coping strategies in a sample of 103 children and adolescents enrolled in the ELENA cohort study in France at diagnosis and three years after diagnosis. Results: Results showed that mothers had higher levels of stress and anxiety / depression than fathers and used more social support coping strategies at diagnosis, which might be explained by increased levels of parental involvement. Mothers' stress level significantly decreased during the three years following ASD diagnosis but no such decrease was observed in fathers' stress level. A significant decrease in anxiety and depression was observed for both parents, suggesting that parental distress is particularly elevated during the critical diagnosis period. Results finally yielded a significant decrease in emotion-focused coping strategy in mothers over the three-year period, an ineffective strategy that takes places at the time of diagnosis but then decreases during the period following ASD diagnosis, in relation to the acceptance process. Conclusions: Implications in terms of addressing the unmet mental health needs of parents and their coping strategies are discussed.
MeSH term(s)	Male ; Child ; Female ; Adolescent ; Humans ; Fathers/psychology ; Mental Health ; Cohort Studies ; Mothers/psychology ; Adaptation, Psychological ; Parents/psychology ; Autism Spectrum Disorder/diagnosis
Language	English
Publishing date	2023-03-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	639175-8
ISSN	1873-3379 ; 0891-4222
ISSN (online)	1873-3379
ISSN	0891-4222
DOI	10.1016/j.ridd.2023.104497
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Article: Adaptation of the working alliance inventory to therapeutic interventions for early-age regulatory and behavioral symptoms: French versions of the infant-toddler WAI for parents and therapists.

Hervé, M-J / Picot, M-C / Maury, M / Kerbage, H / Purper-Ouakil, D

L'Encephale

2022 Volume 49, Issue 6, Page(s) 564–571

Abstract: Objectives: The therapeutic alliance, an essential component of the therapeutic process, has been investigated in adult and child therapy, but studies in the context of parent-infant or parent-toddler therapeutic interventions are scarce. This ... ...

Abstract	Objectives: The therapeutic alliance, an essential component of the therapeutic process, has been investigated in adult and child therapy, but studies in the context of parent-infant or parent-toddler therapeutic interventions are scarce. This monocentric study aims to produce a French cross-cultural adaptation of a therapeutic alliance scale for the context of early consultations in a child and psychiatry department. Method: Fifty-five young children aged 3 to 30 months consulting for regulation or behavioral disorders and their mothers were included in the study. The working alliance inventory (WAI) was translated into French by two bilingual translators and adapted to early-age consultations in parent and therapist versions. Assessments of the child's symptoms and the parents' anxiety and depression were carried out at the start and end of therapy. We studied the association of the alliance with the initial clinical characteristics and with the outcome of the child and the mother. An exploratory factor analysis was performed considering the items most associated with expected outcomes. Results: The alliance coded by the mother was lower in case of child behavioral problems and was associated with the mother and child outcome. Short versions of the infant-toddler WAI were developed based on factor analysis, highlighting four factors: positive goals and tasks, bond with the mother, alliance with the child, negative experience of care relationship. Discussion: Results were similar to those found in therapy with adults or older children. The alliance issue in mother-baby therapies was as essential as in other therapy contexts. The short Infant-Toddler WAI resulting from this work must be validated in future studies.
MeSH term(s)	Adult ; Female ; Humans ; Child, Preschool ; Infant ; Child ; Adolescent ; Psychotherapy/methods ; Mental Disorders ; Parents ; Behavioral Symptoms ; Mothers ; Professional-Patient Relations
Language	English
Publishing date	2022-10-15
Publishing country	France
Document type	Journal Article
ZDB-ID	214431-1
ISSN	0013-7006
ISSN	0013-7006
DOI	10.1016/j.encep.2022.06.010
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