Result 1 - 10 of total 242
Africa Health
| Keywords | covid19 |
|---|---|
| Publisher | WHO |
| Document type | Article |
| Note | WHO #Covidence: #860171 |
| Database | COVID19 |
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2022 Volume 176, Issue 7, Page(s) 728
| MeSH term(s) | Adolescent ; COVID-19 ; Child ; Humans ; Income ; Poverty |
|---|---|
| Language | English |
| Publishing date | 2022-05-19 |
| Publishing country | United States |
| Document type | Journal Article ; Comment |
| ZDB-ID | 2701223-2 |
| ISSN | 2168-6211 ; 2168-6203 |
| ISSN (online) | 2168-6211 |
| ISSN | 2168-6203 |
| DOI | 10.1001/jamapediatrics.2022.1162 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Um IV Zs.74: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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The New England journal of medicine
2023 Volume 389, Issue 1, Page(s) 1–4
| MeSH term(s) | Humans ; Africa/epidemiology ; HIV Infections/drug therapy ; HIV Infections/economics ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; United States ; United States Government Agencies/economics ; United States Government Agencies/organization & administration ; International Cooperation |
|---|---|
| Language | English |
| Publishing date | 2023-07-01 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 207154-x |
| ISSN | 1533-4406 ; 0028-4793 |
| ISSN (online) | 1533-4406 |
| ISSN | 0028-4793 |
| DOI | 10.1056/NEJMp2304600 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.34: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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BMJ global health
2022 Volume 7, Issue 2
| MeSH term(s) | Adolescent ; Africa/epidemiology ; COVID-19 ; Child ; Humans ; SARS-CoV-2 ; Vaccination |
|---|---|
| Language | English |
| Publishing date | 2022-02-10 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, N.I.H., Extramural |
| ISSN | 2059-7908 |
| ISSN | 2059-7908 |
| DOI | 10.1136/bmjgh-2021-008315 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Journal of the International Association of Providers of AIDS Care
2023 Volume 22, Page(s) 23259582231221955
Abstract: Background: ...
| Abstract | Background: |
|---|---|
| MeSH term(s) | Adult ; Child ; Humans ; Adolescent ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Democratic Republic of the Congo/epidemiology ; Retrospective Studies ; Cohort Studies ; Treatment Outcome |
| Language | English |
| Publishing date | 2023-12-25 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2709037-1 |
| ISSN | 2325-9582 ; 2325-9574 |
| ISSN (online) | 2325-9582 |
| ISSN | 2325-9574 |
| DOI | 10.1177/23259582231221955 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2022 Volume 18, Issue 2, Page(s) 126–135
Abstract: HIV-associated cardiomyopathy (HIVAC) is a poorly understood group of diseases with a poor prognosis once ventricular dysfunction is present. Cardiovascular magnetic resonance has revealed a previously unappreciated burden of asymptomatic myocardial ... ...
| Abstract | HIV-associated cardiomyopathy (HIVAC) is a poorly understood group of diseases with a poor prognosis once ventricular dysfunction is present. Cardiovascular magnetic resonance has revealed a previously unappreciated burden of asymptomatic myocardial abnormalities in people living with HIV, including abnormalities already present at the time of HIV diagnosis. These abnormalities include thickened, inflamed ventricles that bear resemblance to cases of symptomatic HIVAC that are reported on in this article. Our understanding and the significance of asymptomatic HIV-associated myocardial pathology will be explored as early disease on a continuum towards more advanced cardiomyopathy. The need for prospective research in persons naïve to anti-retroviral therapy is emphasised as it may provide key findings to better understand this elusive disease process. |
|---|---|
| Language | English |
| Publishing date | 2022-05-04 |
| Publishing country | South Africa |
| Document type | Journal Article |
| ZDB-ID | 2580527-7 |
| ISSN | 2071-4602 ; 2071-4602 |
| ISSN (online) | 2071-4602 |
| ISSN | 2071-4602 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2023 Volume 11, Page(s) 1252886
Abstract: Introduction: Despite the extra mortality associated with COVID-19 death globally, there is scant data on COVID-19-related paediatric mortality in Sub-Saharan Africa. We assessed predictors of critical care needs and hospital mortality in South African ... ...
| Abstract | Introduction: Despite the extra mortality associated with COVID-19 death globally, there is scant data on COVID-19-related paediatric mortality in Sub-Saharan Africa. We assessed predictors of critical care needs and hospital mortality in South African children with laboratory-confirmed SARS-CoV-2 infection in region with high HIV infection burden. Methods: We conducted a secondary multicentre analysis of the AFREhealth cohort (a multinational, multicentre cohort of paediatric COVID-19 clinical outcomes across six African countries) of children admitted to the Inkosi Albert Luthuli, a quaternary hospital in KwaZulu-Natal, South Africa, with confirmed RT-PCR between March 2020 and December 2020. We constructed multivariable logistic regression to explore factors associated with the need for critical care (high care/ intensive care hospitalisation or oxygen requirement) and cox-proportional hazards models to further assess factors independently associated with in-hospital death. Results: Of the 82 children with PCR-confirmed SARS-CoV-2 infection (mean ± SD age: 4.2 ± 4.4 years), 35(42.7%) were younger than one year, 52(63%) were female and 59(71%) had a pre-existing medical condition. Thirty-seven (45.2%) children required critical care (median (IQR) duration: 7.5 (0.5-13.5) days) and 14(17%) died. Independent factors associated with need for critical care were being younger than 1 year (aPR: 3.02, 95%CI: 1.05-8.66; Conclusion: We found a relatively high hospital death rate among children with confirmed COVID-19. During COVID-19 waves, a timely referral system and rapid identification of children at risk for critical care needs and death, such as those less than one year and those with comorbidities, could minimize excess mortality, particularly in high HIV-infection burden countries. |
|---|---|
| Language | English |
| Publishing date | 2023-09-07 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2711999-3 |
| ISSN | 2296-2360 |
| ISSN | 2296-2360 |
| DOI | 10.3389/fped.2023.1252886 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Tropical medicine & international health : TM & IH
2023 Volume 29, Issue 2, Page(s) 88–95
Abstract: Background: Little is known about isoniazid preventive therapy (IPT) completion rates among children or adolescents compared to adults living with HIV in Kinshasa, Democratic Republic of the Congo (DRC).: Methods: We conducted a retrospective cohort ... ...
| Abstract | Background: Little is known about isoniazid preventive therapy (IPT) completion rates among children or adolescents compared to adults living with HIV in Kinshasa, Democratic Republic of the Congo (DRC). Methods: We conducted a retrospective cohort analysis including children, adolescents, and adults living with HIV who were treated at FHI360 and partners-implemented HIV care programs at six health zones in Kinshasa, DRC, from 2004 to 2020. The primary outcome was the proportion of children, adolescents versus adults who did complete 6 months of daily self-administered IPT. Log-binomial regression assessed independent predictors of IPT non-completion and Kaplan-Meier technique for survival analysis. Results: Of 11,691 eligible patients on ART who initiated IPT, 429 were children (<11 years), 804 adolescents (11-19 years), and 10,458 adults (≥20 years). The median age was 7 (IQR: 3-9) years for children, 15 (IQR: 13-17) years for adolescents, and 43 (35-51) years for adults. Among those who were initiated on IPT, 5625 out of 11,691 people living with HIV (PLHIV) had IPT completion outcome results, and an overall 3457/5625 (61.5%) completion rate was documented. Compared to adults, children and adolescents were less likely to complete IPT [104/199 (52.3%) and 268/525 (51.0%), respectively, vs. 3085/4901 (62.9%)]. After adjustment, the only independent predictors for IPT non-completion were health zone of residence and type of ART regimen. Kaplan-Meier analysis showed comparable poor survival among patients who completed IPT versus those who did not (p-value for log-rank test, 0.15). Conclusions: The overall sub-optimal IPT completion rate in adults as well as children/adolescents in this setting is of great concern. Prospective studies are needed to elucidate the specific barriers to IPT completion among children, adolescents, and adults in DRC as well as the scale-up of evidence-informed interventions to improve IPT completion, such as adoption of shorter TB preventive regimens. |
|---|---|
| MeSH term(s) | Adult ; Child ; Humans ; Adolescent ; Child, Preschool ; Isoniazid/therapeutic use ; Latent Tuberculosis ; Antitubercular Agents/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis/prevention & control ; Democratic Republic of the Congo/epidemiology ; Retrospective Studies ; HIV Infections/complications ; HIV Infections/drug therapy |
| Chemical Substances | Isoniazid (V83O1VOZ8L) ; Antitubercular Agents |
| Language | English |
| Publishing date | 2023-12-20 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 1314080-2 |
| ISSN | 1365-3156 ; 1360-2276 |
| ISSN (online) | 1365-3156 |
| ISSN | 1360-2276 |
| DOI | 10.1111/tmi.13952 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 4415: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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2020 Volume 8, Issue 10, Page(s) e1245–e1246
| MeSH term(s) | Anti-HIV Agents ; Delivery of Health Care ; HIV Infections ; Humans ; South Africa ; Uganda |
|---|---|
| Chemical Substances | Anti-HIV Agents |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-09-21 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, N.I.H., Extramural ; Comment |
| ZDB-ID | 2723488-5 |
| ISSN | 2214-109X ; 2214-109X |
| ISSN (online) | 2214-109X |
| ISSN | 2214-109X |
| DOI | 10.1016/S2214-109X(20)30385-5 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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The New England journal of medicine
2021 Volume 385, Issue 3, Page(s) 196–198
| MeSH term(s) | Africa/epidemiology ; Anti-Retroviral Agents/therapeutic use ; Attitude to Health ; COVID-19/prevention & control ; Child ; Female ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Health Promotion ; Humans ; Immunization Programs/organization & administration ; Pandemics ; Pregnancy |
|---|---|
| Chemical Substances | Anti-Retroviral Agents |
| Language | English |
| Publishing date | 2021-03-31 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 207154-x |
| ISSN | 1533-4406 ; 0028-4793 |
| ISSN (online) | 1533-4406 |
| ISSN | 0028-4793 |
| DOI | 10.1056/NEJMp2103313 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.34: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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