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Article ; Online: Projections of functional dependence among the late middle-aged and older population from 2018-2048 in China: a dynamic microsimulation.

Jiang, Yawen / Li, Limin

Global health research and policy

2024 Volume 9, Issue 1, Page(s) 15

Abstract: Background: The population of China is aging rapidly. However, the long-term trajectories of functionally dependent late middle-aged and older Chinese people are currently absent. The present study aimed to estimate the population size and proportion of ...

Abstract	Background: The population of China is aging rapidly. However, the long-term trajectories of functionally dependent late middle-aged and older Chinese people are currently absent. The present study aimed to estimate the population size and proportion of late middle-aged and older adults with difficulties and dependence on activities of daily living (ADL) and instrumental activities of daily living (IADL) in China from 2018 to 2048. Methods: We constructed a dynamic microsimulation model to project the population size and proportions of late middle-aged and older Chinese people who have difficulty and dependence in ADL and IADL from 2018-2048. The model was populated with a representative sample of the target population and allowed individual-level interaction between risk factors, diseases, and health outcomes. Analyses by socioeconomic subgroups were also conducted. Results: Almost 25% and 38% of late middle-aged and older people in China will become ADL- and IADL-dependent by 2048, respectively. Also, 17% of the target population will be severely ADL-disabled by 2048. The inequity in functional status across subgroups by sex, educational level, and urban/rural residency will become substantial. Conclusions: The numbers and percentages of China's functionally difficult and dependent late middle-aged and older population will increase by magnitudes as of the mid-21st century, the pressure of which is compounded by its disproportionate distribution across subgroups. To alleviate the overwhelming challenge, efforts to improve the functional status of the underserved subpopulation should also be iterated.
MeSH term(s)	China ; Humans ; Activities of Daily Living ; Aged ; Middle Aged ; Male ; Female ; Aged, 80 and over ; Forecasting ; Population Dynamics/statistics & numerical data ; Computer Simulation
Language	English
Publishing date	2024-04-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2397-0642
ISSN (online)	2397-0642
DOI	10.1186/s41256-024-00357-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Omicron wave during December 2022 - January 2023: access to pharmaceuticals and healthcare resources and impacts on health outcomes in Shenzhen, China.

Chen, Jiayue / Feng, Haisu / Sun, Jiatong / Jiang, Yawen

Journal of pharmaceutical policy and practice

2024 Volume 17, Issue 1, Page(s) 2306867

Abstract: Purpose: This study described pharmaceutical and medical resource accessibility of COVID-19 treatment in Shenzhen, China during the peak of COVID-19 infection from December 2022 to January 2023, and examined its influence on clinical outcomes.: ... ...

Abstract	Purpose: This study described pharmaceutical and medical resource accessibility of COVID-19 treatment in Shenzhen, China during the peak of COVID-19 infection from December 2022 to January 2023, and examined its influence on clinical outcomes. Methods: We surveyed Shenzhen residents on COVID-19-related topics using electronic questionnaires. We conducted descriptive statistical analyses and multiple regressions including logistic and Tobit models to explore the impacts of resource constraints on patient outcomes. Resource utilisation and attempts to seek medical care were also described for severity-stratified subgroups. Results: 76.8% of respondents reported experiencing COVID-19 symptoms between December 7, 2022 and January 29, 2023. Of those who attempted to purchase medication, 72.8% reported drug shortage. 49% of those seeking medical treatment experienced difficulties. Compared with those who did not experience drug shortages, those who did had an odds ratio of 1.959 (95% CI: 1.159 ∼3.313) of presenting with moderate to severe symptoms. Compared with those without difficulties in seeking medical treatment, those who did had an average of 0.39 (95% CI: 0.110 ∼0.670) more days absent from work. Conclusion: Shenzhen residents with COVID-19 symptoms from December 2022 to January 2023 experienced a certain degree of pharmaceutical and medical resource constraints, which might have compromised their prognosis.
Language	English
Publishing date	2024-02-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2734772-2
ISSN	2052-3211
ISSN	2052-3211
DOI	10.1080/20523211.2024.2306867
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Article ; Online: Title

Zhaojia Ye / Yawen Jiang

Cost Effectiveness and Resource Allocation, Vol 20, Iss 1, Pp 1-

the impact of a pilot integrated care model on the quality and costs of inpatient care among chinese elderly: a difference-in-difference analysis of repeated cross-sectional data

2022 Volume 9

Abstract: Abstract Background Recently, integrated care has received tremendous popularity in China, a leading example of which is the Luohu model. In the present analysis, we aimed to examine the impacts of the Luohu model on the quality and costs of inpatient ... ...

Abstract	Abstract Background Recently, integrated care has received tremendous popularity in China, a leading example of which is the Luohu model. In the present analysis, we aimed to examine the impacts of the Luohu model on the quality and costs of inpatient care. Methods We conducted a retrospective analysis using administrative claims databases of Shenzhen City (the city that the Luohu district sits) from Jan 2015–Apr 2017, which encompassed the time before and after the implementation of the pilot model. The outcomes were 30-day readmission, inpatient costs, and length of stay (LOS). Multivariable difference-in-difference analyses were conducted. Results In the first year following the integration, the Luohu model did not have impacts on any of the outcomes. Although its effect on readmission (ratio of odds ratio: 1.082; 95% CI: 0.865 to 1.353) was still not identified in the first four months of the second post-integration year, it decreased inpatient costs by CN¥ 1224.1 (95% CI: 372.7 to 2075.5) and LOS by 0.938 days (95% CI: 0.0416 to 1.835) per hospitalization episode during the same period. Conclusions The Luohu model may reduce costs and LOS in the long term. It is potentially a viable approach to improve the value of inpatient care in China.
Keywords	Integrated care ; China ; Health maintenance organization ; Elderly ; Value ; Medicine (General) ; R5-920
Subject code	650
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Title: the impact of a pilot integrated care model on the quality and costs of inpatient care among chinese elderly: a difference-in-difference analysis of repeated cross-sectional data.

Ye, Zhaojia / Jiang, Yawen

Cost effectiveness and resource allocation : C/E

2022 Volume 20, Issue 1, Page(s) 28

Abstract: Background: Recently, integrated care has received tremendous popularity in China, a leading example of which is the Luohu model. In the present analysis, we aimed to examine the impacts of the Luohu model on the quality and costs of inpatient care.: ... ...

Abstract	Background: Recently, integrated care has received tremendous popularity in China, a leading example of which is the Luohu model. In the present analysis, we aimed to examine the impacts of the Luohu model on the quality and costs of inpatient care. Methods: We conducted a retrospective analysis using administrative claims databases of Shenzhen City (the city that the Luohu district sits) from Jan 2015-Apr 2017, which encompassed the time before and after the implementation of the pilot model. The outcomes were 30-day readmission, inpatient costs, and length of stay (LOS). Multivariable difference-in-difference analyses were conducted. Results: In the first year following the integration, the Luohu model did not have impacts on any of the outcomes. Although its effect on readmission (ratio of odds ratio: 1.082; 95% CI: 0.865 to 1.353) was still not identified in the first four months of the second post-integration year, it decreased inpatient costs by CN¥ 1224.1 (95% CI: 372.7 to 2075.5) and LOS by 0.938 days (95% CI: 0.0416 to 1.835) per hospitalization episode during the same period. Conclusions: The Luohu model may reduce costs and LOS in the long term. It is potentially a viable approach to improve the value of inpatient care in China.
Language	English
Publishing date	2022-06-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2119372-1
ISSN	1478-7547
ISSN	1478-7547
DOI	10.1186/s12962-022-00361-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Does supplemental private health insurance incentivize household risky financial asset investment? Evidence from the China Household Financial Survey.

Shi, Si / Jiang, Yawen

International journal of health economics and management

2022 Volume 22, Issue 4, Page(s) 369–421

Abstract: Private health insurance (PHI) is considered a supplement to public medical insurance schemes in China. To the extent that PHI coverage may offset background risk by decreasing medical expenditure risk, it may also incentivize risky financial behaviors. ... ...

Abstract	Private health insurance (PHI) is considered a supplement to public medical insurance schemes in China. To the extent that PHI coverage may offset background risk by decreasing medical expenditure risk, it may also incentivize risky financial behaviors. However, empirical evidence confirming this theory is absent in China. We fill this void by examining the impact of supplemental PHI on household risky financial investment using data from the China Household Financial Survey (CHFS). In the first set of analyses, we used bivariate probit (BVP) models with instrumental variables (IVs) to examine the effects of PHI on the extensive margin of household risky financial investment. In the second set of analyses, we used Tobit models with a two-stage residual inclusion (2SRI) framework to examine the effects of PHI on the corresponding intensive margin. The results indicated that supplemental PHI increased the probability of holding risky financial assets. On top of that, PHI increased the percentage of total financial assets allocated to risky financial investment. Such effects were more pronounced on stocks than on other risky products. Our findings provided evidence that purchasing supplemental PHI in China may increase the risk tolerance of financial investment, and risk attitude is a mediating factor between PHI ownership and risky financial investment behavior.
MeSH term(s)	Financial Statements ; Insurance, Health ; Investments ; Health Expenditures ; China
Language	English
Publishing date	2022-03-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	2817492-6
ISSN	2199-9031 ; 2199-9023
ISSN (online)	2199-9031
ISSN	2199-9023
DOI	10.1007/s10754-022-09326-9
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Article ; Online: The Effect of a Video-Assisted Health Education Program Followed by Peer Education on the Health Literacy of COVID-19 and Other Infectious Diseases Among School Children: Quasi-Randomized Controlled Trial.

Zhang, Xiaojuan / Wen, Yingkun Justin / Han, Ning / Jiang, Yawen

JMIR human factors

2024 Volume 11, Page(s) e43943

Abstract: Background: To improve the engagement and effectiveness of traditional health programs, it is necessary to explore alternative models of health education including video-assisted lectures and peer education.: Objective: This study aimed to evaluate ... ...

Abstract	Background: To improve the engagement and effectiveness of traditional health programs, it is necessary to explore alternative models of health education including video-assisted lectures and peer education. Objective: This study aimed to evaluate the effects of a combination of video-assisted lectures and peer education on health literacy related to infectious diseases among students. Methods: Third-grade classes from 11 pilot schools in Longgang District of Shenzhen, China, were randomized to the intervention and control groups. In the intervention group, a video-assisted interactive health education program was conducted twice over a time span of 5 months. Each of the 2 sessions included a 40-minute lecture on COVID-19 and other common infectious diseases in schools and a 5-minute science video. In addition, 5 "little health supervisors" at the end of the first session were elected in each class, who were responsible for helping class members to learn health knowledge and develop good hygiene habits. Students answered the same quiz before the first and after the second session. Models based on item response theory (IRT) were constructed to score the students' knowledge of infectious diseases based on the quiz. Results: In total, 52 classes and 2526 students (intervention group: n=1311; control group: n=1215) were enrolled. Responses of the baseline survey were available for 2177 (86.2%; intervention group: n=1306; control group: n=871) students and those of the postintervention survey were available for 1862 (73.7%; intervention group: n=1187; control group: n=675). There were significant cross-group differences in the rates of correctly answering questions about influenza symptoms, transmission, and preventive measures; chicken pox symptoms; norovirus diarrhea symptoms; mumps symptoms; and COVID-19 symptoms. Average IRT scores of questions related to infectious diseases in the intervention and control groups were, respectively, -0.0375 (SD 0.7784) and 0.0477 (SD 0.7481) before the intervention (P=.01), suggesting better baseline knowledge in the control group. After the intervention, the average scores of the intervention and control groups were 0.0543 (SD 0.7569) and -0.1115 (SD 0.7307), respectively (P<.001), suggesting not only significantly better scores but also greater improvement in the intervention group. Conclusions: After the health education project, the correct answer rate of infectious disease questions in the intervention group was higher than that of the control group, which indicates significant effects of the combination of video-assisted lectures and peer education for the promotion of health literacy. In addition, the intervention effect of the first session persisted for at least 4 months up to the second session. As such, the proposed program was effective in improving the health literacy of school children in relation to infectious diseases and should be considered for massive health promotion campaigns during pandemics. Trial registration: ISRCTN ISRCTN49297995; https://www.isrctn.com/ISRCTN49297995.
MeSH term(s)	Child ; Humans ; Health Literacy ; COVID-19/epidemiology ; Health Education ; Educational Status ; Health Promotion
Language	English
Publishing date	2024-01-29
Publishing country	Canada
Document type	Randomized Controlled Trial ; Journal Article
ISSN	2292-9495
ISSN (online)	2292-9495
DOI	10.2196/43943
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Article ; Online: Evaluation of global climate models for the simulation of precipitation and maximum and minimum temperatures at coarser and finer resolutions based on temporal and spatial assessment metrics in mainland of China

Yawen Lei / Peiyi Peng / Wencui Jiang

Journal of Water and Climate Change, Vol 14, Iss 5, Pp 1585-

2023 Volume 1599

Abstract: Many studies have evaluated the performance of multiple global climate models (GCMs) from a temporal or spatial perspective at finer resolution, but no study has evaluated the performance of individual GCMs at different resolutions and before and after ... ...

Abstract	Many studies have evaluated the performance of multiple global climate models (GCMs) from a temporal or spatial perspective at finer resolution, but no study has evaluated the performance of individual GCMs at different resolutions and before and after bias correction from both temporal and spatial perspectives. The goal of this study is to evaluate the performance of 21 Coupled Model Inter-comparison Project 6 (CMIP6) GCMs at the raw (coarser) and downscaled (finer) resolutions and after bias correction in relation to their skills in the simulation of daily precipitation and maximum and minimum temperatures over China for the period 1961–2014 using state-of-the-art temporal and spatial metrics, Kolmogorov–Smirnov statistic and SPAtial EFficiency. The results indicated some differences in the ranks of GCMs between temporal and spatial metrics at different resolutions. The overall ranking shows that the simulations at the raw resolution of GCMs are more similar to the observations than the simulations after inverse distance weighted interpolation in SPAtial EFficiency. Three variables from bias-corrected GCMs ranked from 1 to 21 show similar good performance in spatial patterns but the poorest trend in empirical Cumulative Distribution Functions (ECDFs) except daily precipitation. HIGHLIGHTS Evaluation of the performance of GCMs for daily precipitation and maximum and minimum temperatures based on spatio-temporal assessment metrics.; Evaluation of the performance of GCMs at coarse and finer resolutions and those after bias correction.;
Keywords	bias correction ; china ; cmip6 gcms ; coarse and finer resolutions ; temporal and spatial metrics ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350
Subject code	910
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	IWA Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: N

Xie, Yawen / Jiang, Cancan / Kuai, Benhai / Xu, Shengjun / Zhuang, Xuliang

Frontiers in bioengineering and biotechnology

2023 Volume 11, Page(s) 1247711

Abstract: Urban wastewater, as the main influent type of Waste Water Treatment Plants (WWTPs), has the characteristic of low carbon to nitrogen ratio (C/N). In the biological nitrogen removal (BNR) process, insufficient carbon source often affects the nitrogen ... ...

Abstract	Urban wastewater, as the main influent type of Waste Water Treatment Plants (WWTPs), has the characteristic of low carbon to nitrogen ratio (C/N). In the biological nitrogen removal (BNR) process, insufficient carbon source often affects the nitrogen removal efficiency and leads to more N
Language	English
Publishing date	2023-11-29
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2719493-0
ISSN	2296-4185
ISSN	2296-4185
DOI	10.3389/fbioe.2023.1247711
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Article: Anti-platelet aggregation activities of different grades of

Shen, Xue / Wu, Yangyang / Chen, Ping / Bai, Yuwei / Liu, Yanan / Jiang, Yihan / Zhang, Yawen / Yang, Zhigang

Frontiers in pharmacology

2024 Volume 14, Page(s) 1230861

Abstract: In traditional Chinese medicine, the radix ... ...

Abstract	In traditional Chinese medicine, the radix of
Language	English
Publishing date	2024-01-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2023.1230861
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Article ; Online: Mixed Metal Components in PM

Wei, Sheng / Xu, Ting / Sang, Nan / Yue, Huifeng / Chen, Yawen / Jiang, Tao / Jiang, Tingwang / Yin, Daqiang

Environmental science & technology

2024 Volume 58, Issue 11, Page(s) 4914–4925

Abstract: Particulate matter, especially ... ...

Abstract	Particulate matter, especially PM
MeSH term(s)	Mice ; Animals ; Neuroinflammatory Diseases ; Olfactory Bulb/metabolism ; Particulate Matter/toxicity ; Signal Transduction ; Receptors, Chemokine/metabolism ; NF-kappa B/metabolism ; NF-kappa B/pharmacology
Chemical Substances	Particulate Matter ; Receptors, Chemokine ; NF-kappa B
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Journal Article
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.3c08506
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