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Article ; Online: The currency and completeness of specialized databases of COVID-19 publications.

Butcher, Robyn / Sampson, Margaret / Couban, Rachel J / Malin, James Edward / Loree, Sara / Brody, Stacy

2022 Volume 147, Page(s) 52–59

Abstract: Objective: Several specialized collections of COVID-19 literature have been developed during the global health emergency. These include the WHO COVID-19 Global Literature Database, Cochrane COVID-19 Study Register, CAMARADES COVID-19 SOLES, ... ...

Abstract	Objective: Several specialized collections of COVID-19 literature have been developed during the global health emergency. These include the WHO COVID-19 Global Literature Database, Cochrane COVID-19 Study Register, CAMARADES COVID-19 SOLES, Epistemonikos' COVID-19 L-OVE, and LitCovid. Our objective was to evaluate the completeness of these collections and to measure the time from when COVID-19 articles are posted to when they appear in the collections. Study design and setting: We tested each selected collection for the presence of 440 included studies from 25 COVID-19 systematic reviews. We sampled 112 journals and prospectively monitored their websites until a new COVID-19 article appeared. We then monitored for 2 weeks to see when the new articles appeared in each collection. PubMed served as a comparator. Results: Every collection provided at least one record not found in PubMed. Four records (1%) were not in any of the sources studied. Collections contained between 83% and 93% of the primary studies with the WHO database being the most complete. By 2 weeks, between 60% and 78% of tracked articles had appeared. Conclusion: Our findings support the use of the best performing COVID-19 collections by systematic reviews to replace paywalled databases.
MeSH term(s)	COVID-19/epidemiology ; Databases, Factual ; Humans ; PubMed
Language	English
Publishing date	2022-03-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2022.03.006
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Article ; Online: Development and examination of a rubric for evaluating point-of-care medical applications for mobile devices.

Butcher, Robyn / MacKinnon, Martin / Gadd, Kathleen / LeBlanc-Duchin, Denise

Medical reference services quarterly

2015 Volume 34, Issue 1, Page(s) 75–87

Abstract: The rapid development and updates of mobile medical resource applications (apps) highlight the need for an evaluation tool to assess the content of these resources. The purpose of the study was to develop and test a new evaluation rubric for medical ... ...

Abstract	The rapid development and updates of mobile medical resource applications (apps) highlight the need for an evaluation tool to assess the content of these resources. The purpose of the study was to develop and test a new evaluation rubric for medical resource apps. The evaluation rubric was designed using existing literature and through a collaborative effort between a hospital and an academic librarian. Testing found scores ranging from 23% to 88% for the apps. The evaluation rubric proved able to distinguish levels of quality within each content component of the apps, demonstrating potential for standardization of medical resource app evaluations.
MeSH term(s)	Cell Phone ; Decision Support Systems, Clinical ; Evaluation Studies as Topic ; Humans ; Mobile Applications/standards ; Point-of-Care Systems ; United States
Language	English
Publishing date	2015
Publishing country	United States
Document type	Journal Article
ZDB-ID	605941-7
ISSN	1540-9597 ; 0276-3869
ISSN (online)	1540-9597
ISSN	0276-3869
DOI	10.1080/02763869.2015.986794
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Article ; Online: Test-Retest Reliability and Physiological Responses Associated with the Steep Ramp Anaerobic Test in Patients with COPD.

Chura, Robyn L / Marciniuk, Darcy D / Clemens, Ron / Butcher, Scotty J

Pulmonary medicine

2012 Volume 2012, Page(s) 653831

Abstract: The Steep Ramp Anaerobic Test (SRAT) was developed as a clinical test of anaerobic leg muscle function for use in determining anaerobic power and in prescribing high-intensity interval exercise in patients with chronic heart failure and Chronic ... ...

Abstract	The Steep Ramp Anaerobic Test (SRAT) was developed as a clinical test of anaerobic leg muscle function for use in determining anaerobic power and in prescribing high-intensity interval exercise in patients with chronic heart failure and Chronic Obstructive Pulmonary Disease (COPD); however, neither the test-retest reliability nor the physiological qualities of this test have been reported. We therefore, assessed test-retest reliability of the SRAT and the physiological characteristics associated with the test in patients with COPD. 11 COPD patients (mean FEV(1) 43% predicted) performed a cardiopulmonary exercise test (CPET) on Day 1, and an SRAT and a 30-second Wingate anaerobic test (WAT) on each of Days 2 and 3. The SRAT showed a high degree of test-retest reliability (ICC = 0.99; CV = 3.8%, and bias 4.5 W, error -15.3-24.4 W). Power output on the SRAT was 157 W compared to 66 W on the CPET and 231 W on the WAT. Despite the differences in workload, patients exhibited similar metabolic and ventilatory responses between the three tests. Measures of ventilatory constraint correlated more strongly with the CPET than the WAT; however, physiological variables correlated more strongly with the WAT. The SRAT is a highly reliable test that better reflects physiological performance on a WAT power test despite a similar level of ventilatory constraint compared to CPET.
Language	English
Publishing date	2012-06-06
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2603580-7
ISSN	2090-1844 ; 2090-1844
ISSN (online)	2090-1844
ISSN	2090-1844
DOI	10.1155/2012/653831
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Associations between isokinetic muscle strength, high-level functional performance, and physiological parameters in patients with chronic obstructive pulmonary disease.

Butcher, Scotty J / Pikaluk, Brendan J / Chura, Robyn L / Walkner, Mark J / Farthing, Jonathan P / Marciniuk, Darcy D

International journal of chronic obstructive pulmonary disease

2012 Volume 7, Page(s) 537–542

Abstract: High-level activities are typically not performed by patients with chronic obstructive pulmonary disease (COPD), which results in reduced functional performance; however, the physiological parameters that contribute to this reduced performance are ... ...

Abstract	High-level activities are typically not performed by patients with chronic obstructive pulmonary disease (COPD), which results in reduced functional performance; however, the physiological parameters that contribute to this reduced performance are unknown. The aim of this study was to determine the relationships between high-level functional performance, leg muscle strength/power, aerobic power, and anaerobic power. Thirteen patients with COPD underwent an incremental maximal cardiopulmonary exercise test, quadriceps isokinetic dynamometry (isometric peak torque and rate of torque development; concentric isokinetic peak torque at 90°/sec, 180°/sec, and 270°/sec; and eccentric peak torque at 90°/sec), a steep ramp anaerobic test (SRAT) (increments of 25 watts every 10 seconds), and three functional measures (timed up and go [TUG], timed stair climb power [SCPT], and 30-second sit-to-stand test [STS]). TUG time correlated strongly (P < 0.05) with all muscle strength variables and with the SRAT. Isometric peak torque was the strongest determinant of TUG time (r = -0.92). SCPT and STS each correlated with all muscle strength variables except concentric at 270°/sec and with the SRAT. The SRAT was the strongest determinant of SCPT (r = 0.91), and eccentric peak torque at 90°/sec was most significantly associated with STS (r = 0.81). Performance on the SRAT (anaerobic power); slower-velocity concentric, eccentric, and isometric contractions; and rate of torque development are reflected in all functional tests, whereas cardiopulmonary exercise test performance (aerobic power) was not associated with any of the functional or muscle tests. High-level functional performance in patients with COPD is associated with physiological parameters that require high levels of muscle force and anaerobic work rates.
MeSH term(s)	Aged ; Biomechanical Phenomena ; Cross-Over Studies ; Exercise Test ; Female ; Humans ; Isometric Contraction ; Lower Extremity ; Lung/physiopathology ; Male ; Muscle Strength ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Quadriceps Muscle/physiopathology ; Respiratory Function Tests ; Saskatchewan ; Torque
Language	English
Publishing date	2012-08-22
Publishing country	New Zealand
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2212419-6
ISSN	1178-2005 ; 1176-9106
ISSN (online)	1178-2005
ISSN	1176-9106
DOI	10.2147/COPD.S34170
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Critical role for the chemokine receptor CXCR6 in homeostasis and activation of CD1d-restricted NKT cells.

Germanov, Elitza / Veinotte, Linnea / Cullen, Robyn / Chamberlain, Erin / Butcher, Eugene C / Johnston, Brent

Journal of immunology (Baltimore, Md. : 1950)

2008 Volume 181, Issue 1, Page(s) 81–91

Abstract: NK T (NKT) cells play important roles in the regulation of diverse immune responses. However, little is known about the mechanisms that regulate homeostasis and activation of these cells. Thymic NKT cells up-regulated the chemokine receptor CXCR6 ... ...

Abstract	NK T (NKT) cells play important roles in the regulation of diverse immune responses. However, little is known about the mechanisms that regulate homeostasis and activation of these cells. Thymic NKT cells up-regulated the chemokine receptor CXCR6 following positive selection and migrated toward CXCL16 in vitro. However, CXCR6 was not essential for thymic development or maturation. In contrast, liver and lung NKT cells were depleted in CXCR6+/- and CXCR6-/- mice. The reduction in liver and lung NKT cells coincided with an increase in bone marrow NKT cells, suggesting a redistribution of NKT cells in CXCR6-/- animals. In wild-type mice, CXCL16 neutralization reduced accumulation of mature NK1.1+, but not immature NK1.1- NKT cell recent thymic emigrants in the liver. Given that thymic NKT cells are preferentially exported as NK1.1- cells, this suggests an additional role for CXCR6/CXCL16 in maturation or survival of immature liver NKT cells. CXCL16 blockade did not deplete resident NK1.1+ NKT cells, indicating that CXCR6/CXCL16 are not required to retain mature NKT cells in the liver. Cytokine production by liver and spleen NKT cells was impaired in CXCR6-/- mice following in vivo stimulation with alpha-galactosylceramide, implicating a novel role for CXCR6 in NKT cell activation. Reduced IFN-gamma production was not due to an intrinsic defect as production was normal following PMA and ionomycin stimulation. Preformed transcripts for IL-4, but not IFN-gamma, were reduced in CXCR6-/- liver NKT cells. These data identify critical roles for CXCR6/CXCL16 in NKT cell activation and the regulation of NKT cell homeostasis.
MeSH term(s)	Animals ; Antigens, CD1/immunology ; Antigens, CD1/metabolism ; Antigens, CD1d ; Cell Differentiation/immunology ; Cell Movement/immunology ; Cells, Cultured ; Cytokines/biosynthesis ; Cytokines/immunology ; Female ; Homeostasis/immunology ; Liver/immunology ; Lymphocyte Activation/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, CXCR/deficiency ; Receptors, CXCR/genetics ; Receptors, CXCR/immunology ; Receptors, CXCR/metabolism ; Receptors, CXCR6 ; T-Lymphocytes, Regulatory/cytology ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Thymus Gland/immunology ; Up-Regulation/immunology
Chemical Substances	Antigens, CD1 ; Antigens, CD1d ; Cxcr6 protein, mouse ; Cytokines ; Receptors, CXCR ; Receptors, CXCR6
Language	English
Publishing date	2008-05-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3056-9
ISSN	1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
ISSN (online)	1550-6606
ISSN	0022-1767 ; 1048-3233 ; 1047-7381
DOI	10.4049/jimmunol.181.1.81
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Article ; Online: HADStress: a somatic symptom screen for posttraumatic stress among Somali refugees.

Westermeyer, Joseph J / Campbell, Robyn / Lien, Rebecca / Spring, Marline / Johnson, David R / Butcher, James / Hyland, Jacqueline / Thuras, Paul / Jaranson, James M

Psychiatric services (Washington, D.C.)

2010 Volume 61, Issue 11, Page(s) 1132–1137

Abstract: Objective: This study assessed whether a simple, readily implemented four-symptom somatic screen would be able to effectively identify current posttraumatic stress symptoms in victimized populations.: Methods: The sample consisted of 622 Somali ... ...

Abstract	Objective: This study assessed whether a simple, readily implemented four-symptom somatic screen would be able to effectively identify current posttraumatic stress symptoms in victimized populations. Methods: The sample consisted of 622 Somali community-dwelling refugees who fled widespread violence and trauma occurring in East Africa during 1990-1992. Data were collected during 2000-2003 and included demographic characteristics, number of types of torture and nontorture trauma experienced earlier in Africa, and current self-rated posttraumatic stress symptoms, as measured by the Posttraumatic Stress Disorder Checklist (PCL). The sample was also assessed with the HADStress screen, which was developed for this study, to determine whether the screen was effective in detecting current posttraumatic stress symptoms. The HADStress screen assessed for the presence of four somatic symptoms: Headaches, Appetite change, Dizziness, and Sleep problems. All items were given equal weight. Possible scores on the screen range from 0 to 4, with higher scores indicating more somatic symptoms. Results: Univariate analysis showed that persons who experienced more types of trauma (both torture and nontorture trauma) and persons who had higher PCL scores (indicating more current posttraumatic stress symptoms) had significantly higher HADStress scores. Negative binomial regression analysis showed that PCL scores were the most effective variable in predicting HADStress scores. On the Tukey-B post hoc analysis, a HADStress score of 0 or 1 was associated with a mean PCL score of less than 30, a score of 2 was associated with a mean PCL score of 40.28, and a score of 4 was associated with a mean PCL score of 51.07 (suggesting that over 50% of this group would have active posttraumatic stress disorder). Conclusions: A score of 2 or higher on the HADStress scale among refugees warrants additional evaluation for posttraumatic stress symptoms in clinical settings. For communitywide efforts at early recognition and treatment, a cutoff score of 4 may be more practical and cost-effective.
MeSH term(s)	Adult ; Analysis of Variance ; Chi-Square Distribution ; Female ; Health Status Indicators ; Humans ; Male ; Minnesota/epidemiology ; Poisson Distribution ; Psychiatric Status Rating Scales ; Refugees/psychology ; Regression Analysis ; Somalia/ethnology ; Somatoform Disorders/diagnosis ; Somatoform Disorders/epidemiology ; Somatoform Disorders/psychology ; Stress Disorders, Post-Traumatic/diagnosis ; Stress Disorders, Post-Traumatic/psychology ; Torture/psychology
Language	English
Publishing date	2010-11
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/ps.2010.61.11.1132
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Article ; Online: Associations between isokinetic muscle strength, high-level functional performance, and physiological parameters in patients with chronic obstructive pulmonary disease

Butcher SJ / Pikaluk BJ / Chura RL / Walkner MJ / Farthing JP / Marciniuk DD

International Journal of COPD, Vol 2012, Iss default, Pp 537-

2012 Volume 542

Abstract: Scotty J Butcher,1 Brendan J Pikaluk,2 Robyn L Chura,1 Mark J Walkner,1 Jonathan P Farthing,2 Darcy ...

Abstract	Scotty J Butcher,1 Brendan J Pikaluk,2 Robyn L Chura,1 Mark J Walkner,1 Jonathan P Farthing,2 Darcy D Marciniuk31School of Physical Therapy, University of Saskatchewan, Saskatoon, SK, Canada; 2College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada; 3Division of Respiratory, Critical Care and Sleep Medicine, University of Saskatchewan, Saskatoon, SK, CanadaAbstract: High-level activities are typically not performed by patients with chronic obstructive pulmonary disease (COPD), which results in reduced functional performance; however, the physiological parameters that contribute to this reduced performance are unknown. The aim of this study was to determine the relationships between high-level functional performance, leg muscle strength/power, aerobic power, and anaerobic power. Thirteen patients with COPD underwent an incremental maximal cardiopulmonary exercise test, quadriceps isokinetic dynamometry (isometric peak torque and rate of torque development; concentric isokinetic peak torque at 90°/sec, 180°/sec, and 270°/sec; and eccentric peak torque at 90°/sec), a steep ramp anaerobic test (SRAT) (increments of 25 watts every 10 seconds), and three functional measures (timed up and go [TUG], timed stair climb power [SCPT], and 30-second sit-to-stand test [STS]). TUG time correlated strongly (P < 0.05) with all muscle strength variables and with the SRAT. Isometric peak torque was the strongest determinant of TUG time (r = –0.92). SCPT and STS each correlated with all muscle strength variables except concentric at 270°/sec and with the SRAT. The SRAT was the strongest determinant of SCPT (r = 0.91), and eccentric peak torque at 90°/sec was most significantly associated with STS (r = 0.81). Performance on the SRAT (anaerobic power); slower-velocity concentric, eccentric, and isometric contractions; and rate of torque development are reflected in all functional tests, whereas cardiopulmonary exercise test performance (aerobic power) was not associated with any of the functional or muscle tests. High-level functional performance in patients with COPD is associated with physiological parameters that require high levels of muscle force and anaerobic work rates.Keywords: stair climb, sit to stand, timed up and go, steep ramp, isokinetic
Keywords	Diseases of the respiratory system ; RC705-779 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	796
Language	English
Publishing date	2012-08-01T00:00:00Z
Publisher	Dove Medical Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The currency and completeness of specialized databases of COVID-19 publications.

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Article ; Online: Development and examination of a rubric for evaluating point-of-care medical applications for mobile devices.

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Article ; Online: Test-Retest Reliability and Physiological Responses Associated with the Steep Ramp Anaerobic Test in Patients with COPD.

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Article ; Online: Associations between isokinetic muscle strength, high-level functional performance, and physiological parameters in patients with chronic obstructive pulmonary disease.

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Article: Critical role for the chemokine receptor CXCR6 in homeostasis and activation of CD1d-restricted NKT cells.

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Article ; Online: HADStress: a somatic symptom screen for posttraumatic stress among Somali refugees.

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Article ; Online: Associations between isokinetic muscle strength, high-level functional performance, and physiological parameters in patients with chronic obstructive pulmonary disease

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