LIVIVO - Search results -

Search results

Result 1 - 10 of total 450

Search options

Article ; Online: A Pandemic's Impact: Newly Licensed Nurse Self-Efficacy Following Increased Use of Simulation.

Grimm, Khristina L / Barker, Sarah

Journal for nurses in professional development

2022 Volume 39, Issue 5, Page(s) E108–E111

Abstract: The purpose of this comparative study was to identify the difference in self-efficacy in nursing practice of newly licensed nurses who transitioned to acute care during the pandemic to those who transitioned prior to the pandemic. Analysis revealed no ... ...

Abstract	The purpose of this comparative study was to identify the difference in self-efficacy in nursing practice of newly licensed nurses who transitioned to acute care during the pandemic to those who transitioned prior to the pandemic. Analysis revealed no significant difference in the overall self-efficacy scores of the groups. However, a significant difference was identified in questions related to self-efficacy with death and finding nursing exciting. Findings of this study provide insight for providing orientation for nurses regarding their readiness to practice.
MeSH term(s)	Humans ; Self Efficacy ; Pandemics ; Nurses
Language	English
Publishing date	2022-01-20
Publishing country	United States
Document type	Journal Article
ISSN	2169-981X
ISSN (online)	2169-981X
DOI	10.1097/NND.0000000000000848
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Preferential associations in an unstable social network: applying social network analysis to a dynamic sow herd.

Jowett, Sarah L / Barker, Zoe Elizabeth / Amory, Jonathan R

Frontiers in veterinary science

2023 Volume 10, Page(s) 1166632

Abstract: Preferential associations are fitness-enhancing ties between individuals, documented in a range of taxa. Despite this, research into preferential associations remains underrepresented in commercial species, particularly pigs. This study investigates the ... ...

Abstract	Preferential associations are fitness-enhancing ties between individuals, documented in a range of taxa. Despite this, research into preferential associations remains underrepresented in commercial species, particularly pigs. This study investigates the development of preferential associations in a dynamic sow herd. Preferential associations were defined as approaching a resting sow and then sitting or lying with physical contact with the selected sow, separated by < 1 m from the head or directly next to her, with interaction tolerated for > 60 s. For individual identification, each sow was marked with colored dots, stripes, or both, corresponding to their ear-tag number. Preferential associations were measured over one production cycle of 21 days. Behavioral observations took place on 7 days of the study, with 3 h of behavior per day recorded during peak activity times (08:00-09:00, 15:00-16:00, 20:00-21:00 h). Behaviors were recorded using five cameras, each positioned within the barn to provide coverage of the functional areas. The network metrics applied included in-degree centrality (received ties), out-degree centrality (initiated ties), centralization (the extent to which an individual is central within the network), clustering coefficient (a measure of tie strength), and the E-I Index (a measure of assortment by trait: parity, familiarity, and sociality). Individuals were added and removed during the study, so the centrality metrics of missing sows were weighted. To describe the structure of the network, brokerage typologies were applied. Brokerage typologies include five positions, including coordinators, gatekeepers, representatives, consultants, and liaisons. The results revealed social discrimination in assortment by connectedness even when ties were not reciprocal, and the most connected sows were significantly more likely to be approached than less connected individuals. The most connected sows had significantly higher in-degree and out-degree centrality. With the application of brokerage typologies, the results showed a relationship between connectedness and brokering type, with the most connected sows predominantly engaging in coordinating behavior. The results suggest that the motivation for discrimination in the unstable preferential association network was not founded upon bidirectional interactions. These findings highlight the complexities involved when forming social preferences and present a platform for further exploring the motivations for preferential associations among intensively farmed pigs.
Language	English
Publishing date	2023-06-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2023.1166632
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Exploring the predictors of financial impairment in Huntington's disease using the Enroll-HD dataset.

Harris, Kate L / Mason, Sarah L / Barker, Roger A

Journal of neurology

2022 Volume 269, Issue 7, Page(s) 3501–3510

Abstract: Objectives: Huntington's disease (HD) is a neurodegenerative disease in which cognitive and behavioural symptoms impair the performance of instrumental activities of daily living, including the handling of finances. We sought to determine the prevalence ...

Abstract	Objectives: Huntington's disease (HD) is a neurodegenerative disease in which cognitive and behavioural symptoms impair the performance of instrumental activities of daily living, including the handling of finances. We sought to determine the prevalence of financial dysfunction in HD, and the demographic and clinical predictors of such impairments. Methods: We analysed longitudinal data for pre-manifest gene carriers and HD patients from the Enroll-HD dataset. Financial dysfunction was determined by finance-related items in the Total Functional Capacity (TFC) and Functional Assessment (FA) scales. A binary logistical regression model was used to investigate the predictive value of demographic and clinical factors for the development of financial dysfunction. Results: Financial impairment was found to be common in HD gene carriers, and over half required financial assistance within 5 years from diagnosis. Cognitive impairment, apathy, unemployment and disease severity predicted financial dysfunction in manifest patients. For pre-manifest patients, the predictors were proximity to disease onset and depression. Conclusions: Loss of financial autonomy is common in HD, and cognitive and psychiatric factors are important in its development. Clinicians must be vigilant to identify patients that may be vulnerable to financial exploitation.
MeSH term(s)	Activities of Daily Living ; Apathy ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/etiology ; Humans ; Huntington Disease/complications ; Huntington Disease/epidemiology ; Huntington Disease/genetics ; Neurodegenerative Diseases
Language	English
Publishing date	2022-02-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	187050-6
ISSN	1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
ISSN (online)	1432-1459
ISSN	0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
DOI	10.1007/s00415-021-10929-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Ui II Zs.40: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Preferential associations in an unstable social network

Sarah L. Jowett / Zoe Elizabeth Barker / Jonathan R. Amory

Frontiers in Veterinary Science, Vol

applying social network analysis to a dynamic sow herd

2023 Volume 10

Abstract	Preferential associations are fitness-enhancing ties between individuals, documented in a range of taxa. Despite this, research into preferential associations remains underrepresented in commercial species, particularly pigs. This study investigates the development of preferential associations in a dynamic sow herd. Preferential associations were defined as approaching a resting sow and then sitting or lying with physical contact with the selected sow, separated by < 1 m from the head or directly next to her, with interaction tolerated for > 60 s. For individual identification, each sow was marked with colored dots, stripes, or both, corresponding to their ear-tag number. Preferential associations were measured over one production cycle of 21 days. Behavioral observations took place on 7 days of the study, with 3 h of behavior per day recorded during peak activity times (08:00–09:00, 15:00–16:00, 20:00–21:00 h). Behaviors were recorded using five cameras, each positioned within the barn to provide coverage of the functional areas. The network metrics applied included in-degree centrality (received ties), out-degree centrality (initiated ties), centralization (the extent to which an individual is central within the network), clustering coefficient (a measure of tie strength), and the E-I Index (a measure of assortment by trait: parity, familiarity, and sociality). Individuals were added and removed during the study, so the centrality metrics of missing sows were weighted. To describe the structure of the network, brokerage typologies were applied. Brokerage typologies include five positions, including coordinators, gatekeepers, representatives, consultants, and liaisons. The results revealed social discrimination in assortment by connectedness even when ties were not reciprocal, and the most connected sows were significantly more likely to be approached than less connected individuals. The most connected sows had significantly higher in-degree and out-degree centrality. With the application of brokerage ...
Keywords	preferential association ; network ; connectedness ; motivation ; pig ; social tie ; Veterinary medicine ; SF600-1100
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: The hunt for better treatments for Huntington's disease.

Barker, Roger / Mason, Sarah L

The Lancet. Neurology

2018 Volume 18, Issue 2, Page(s) 131–133

MeSH term(s)	Humans ; Huntington Disease ; Piperidines
Chemical Substances	Piperidines ; pridopidine (HD4TW8S2VK)
Language	English
Publishing date	2018-12-15
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	2079704-7
ISSN	1474-4465 ; 1474-4422
ISSN (online)	1474-4465
ISSN	1474-4422
DOI	10.1016/S1474-4422(18)30448-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Metacognitive insight into cognitive performance in Huntington's disease gene carriers.

Hewitt, Samuel Rc / White, Alice J / Mason, Sarah L / Barker, Roger A

BMJ neurology open

2022 Volume 4, Issue 1, Page(s) e000268

Abstract: Objectives: Insight is an important predictor of quality of life in Huntington's disease and other neurodegenerative conditions. However, estimating insight with traditional methods such as questionnaires is challenging and subjected to limitations. ... ...

Abstract	Objectives: Insight is an important predictor of quality of life in Huntington's disease and other neurodegenerative conditions. However, estimating insight with traditional methods such as questionnaires is challenging and subjected to limitations. This cross-sectional study experimentally quantified metacognitive insight into cognitive performance in Huntington's disease gene carriers. Methods: We dissociated perceptual decision-making performance and metacognitive insight into performance in healthy controls (n=29), premanifest (n=19) and early-manifest (n=10) Huntington's disease gene carriers. Insight was operationalised as the degree to which a participant's confidence in their performance was informative of their actual performance (metacognitive efficiency) and estimated using a computational model (HMeta-d'). Results: We found that premanifest and early-manifest Huntington's disease gene carriers were impaired in making perceptual decisions compared with controls. Gene carriers required more evidence in favour of the correct choice to achieve similar performance and perceptual impairments were increased in those with manifest disease. Surprisingly, despite marked perceptual impairments, Huntington's disease gene carriers retained metacognitive insight into their perceptual performance. This was the case after controlling for confounding variables and regardless of disease stage. Conclusion: We report for the first time a dissociation between impaired cognition and intact metacognition (trial-by-trial insight) in the early stages of a neurodegenerative disease. This unexpected finding contrasts with the prevailing assumption that cognitive deficits are associated with impaired insight. Future studies should investigate how intact metacognitive insight could be used by some early Huntington's disease gene carriers to positively impact their quality of life.
Language	English
Publishing date	2022-04-05
Publishing country	England
Document type	Journal Article
ISSN	2632-6140
ISSN (online)	2632-6140
DOI	10.1136/bmjno-2022-000268
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Problems with Social Cognition and Decision-Making in Huntington's Disease: Why Is it Important?

Mason, Sarah L / Schaepers, Miriam / Barker, Roger A

Brain sciences

2021 Volume 11, Issue 7

Abstract: Huntington's disease starts slowly and progresses over a 15-20 year period. Motor changes begin subtly, often going unnoticed by patients although they are typically visible to those close to them. At this point, it is the early non-motor problems of HD ... ...

Abstract	Huntington's disease starts slowly and progresses over a 15-20 year period. Motor changes begin subtly, often going unnoticed by patients although they are typically visible to those close to them. At this point, it is the early non-motor problems of HD that arguably cause the most functional impairment. Approximately 65% of gene carriers will experience a reduction in their occupational level, and just under half will feel unable to manage their finances independently before a clinical diagnosis is made. Understanding what drives this impairment in activities of daily living is the key to helping people with HD to live more independently for longer, especially in early disease. Early cognitive decline is likely to play a contributory factor although few studies have looked directly at this relationship. Recently, it has been shown that along with the well documented dysexecutive syndrome seen in HD, changes in social cognition and decision-making are more common than previously thought. Furthermore, some of the early neuropathological and neurochemical changes seen in HD disrupt networks known to be involved in social functioning. In this review, we explore how HD changes the way individuals interact in a social world. Specifically, we summarise the literature on both classical and social decision-making (value-based decision-making in a social context) along with studies of theory of mind, empathy, alexithymia, and emotion recognition in HD. The literature specific to HD is discussed and supported by evidence from similar neurodegenerative disorders and healthy individuals to propose future directions and potential therapeutic avenues to be explored.
Language	English
Publishing date	2021-06-24
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2651993-8
ISSN	2076-3425
ISSN	2076-3425
DOI	10.3390/brainsci11070838
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Assessment of costs and insurance policies for referral treatment of equine colic.

Barker, Isobel / Freeman, Sarah L

The Veterinary record

2019 Volume 185, Issue 16, Page(s) 508

Abstract: Colic is the most common emergency problem in horses. The aims of this study were to survey costs of different referral treatments and to review insurance policies relevant to horses with colic. Data were collected retrospectively from nine equine ... ...

Abstract	Colic is the most common emergency problem in horses. The aims of this study were to survey costs of different referral treatments and to review insurance policies relevant to horses with colic. Data were collected retrospectively from nine equine hospitals for case costs, categorised into four different outcomes: admitted and euthanased; euthanased during or immediately after surgery; medical treatment and survived more than 24 hours; and surgical treatment and survived more than 24 hours. Data from five UK equine insurance companies were extracted and analysed using a standardised case example. Costs were obtained for 108 cases. The mean cost for horses admitted and euthanased was £873.89 (range £459.72-£1471.51), and for surgical treatment and survival more than 24 hours was £6437.80 (range £3178.87-£9100.00). Insurance cover for veterinary fees ranged from £5000 to £7500, and monthly premium rates for a standardised case ranged from £27.06 to £47.06. The terms and conditions for the insurance policies ranged in length from 2098 to 17,701 words; Flesch Kincaid Reading Ease scores ranged from 21.6 to 57.7, indicating a high degree of complexity and low readability. This study highlights the complexity and challenges for decision-making in critical cases of colic.
MeSH term(s)	Animals ; Colic/therapy ; Colic/veterinary ; Costs and Cost Analysis ; Horse Diseases/therapy ; Horses ; Hospitals, Animal/economics ; Humans ; Insurance, Health/economics ; Referral and Consultation/economics ; Retrospective Studies ; United Kingdom
Language	English
Publishing date	2019-08-22
Publishing country	England
Document type	Journal Article
ZDB-ID	390015-0
ISSN	2042-7670 ; 0042-4900
ISSN (online)	2042-7670
ISSN	0042-4900
DOI	10.1136/vr.105415
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 645: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development.

Edwards, Whitney / Greco, Todd M / Miner, Gregory E / Barker, Natalie K / Herring, Laura / Cohen, Sarah / Cristea, Ileana M / Conlon, Frank L

Developmental cell

2023 Volume 58, Issue 12, Page(s) 1087–1105.e4

Abstract: Defining the mechanisms that govern heart development is essential for identifying the etiology of congenital heart disease. Here, quantitative proteomics was used to measure temporal changes in the proteome at critical stages of murine embryonic heart ... ...

Abstract	Defining the mechanisms that govern heart development is essential for identifying the etiology of congenital heart disease. Here, quantitative proteomics was used to measure temporal changes in the proteome at critical stages of murine embryonic heart development. Global temporal profiles of the over 7,300 proteins uncovered signature cardiac protein interaction networks that linked protein dynamics with molecular pathways. Using this integrated dataset, we identified and demonstrated a functional role for the mevalonate pathway in regulating the cell cycle of embryonic cardiomyocytes. Overall, our proteomic datasets are a resource for studying events that regulate embryonic heart development and contribute to congenital heart disease.
MeSH term(s)	Animals ; Mice ; Proteomics ; Heart Defects, Congenital ; Myocytes, Cardiac/metabolism ; Embryonic Development/genetics ; Proteome/metabolism
Chemical Substances	Proteome
Language	English
Publishing date	2023-05-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2054967-2
ISSN	1878-1551 ; 1534-5807
ISSN (online)	1878-1551
ISSN	1534-5807
DOI	10.1016/j.devcel.2023.04.011
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5742: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 76: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Anti-chemotactic activity in the secretory/excretory products of Lepeophtheirus salmonis.

Piesz, Jessica L / Barker, Sarah E / Bricknell, Ian R

Fish & shellfish immunology

2020 Volume 98, Page(s) 296–300

Abstract: ... from its host, Atlantic salmon, Salmo salar L., by inhibiting the recruitment of immune cells to the site ... chemokines preventing their interaction with receptors on the surfaces of immune cells. To determine if L ... migration compared to LTB4 immune stimulation alone. Data suggests that one of the mechanisms L. salmonis ...

Abstract	The ectoparasite, Lepeophtheirus salmonis (Kroyer 1837), is effective at avoiding elimination from its host, Atlantic salmon, Salmo salar L., by inhibiting the recruitment of immune cells to the site of attachment. In other ectoparasitic arthropods, numerous factors have been identified that bind or neutralize chemokines preventing their interaction with receptors on the surfaces of immune cells. To determine if L. salmonis is utilizing a similar mechanism of immune modulation, the chemotactic activity of peripheral blood leukocytes (PBL) to leukotriene B4 (LTB4) and the secreted/excreted products (SEPs) of the sea louse were investigated in vitro. The results showed that incubation of LTB4 with SEPs reduced leukocyte migration compared to LTB4 immune stimulation alone. Data suggests that one of the mechanisms L. salmonis may be using to regulate immune cell recruitment in Atlantic salmon is by inhibiting or neutralizing the activity of chemokines.
MeSH term(s)	Animals ; Chemotaxis/immunology ; Copepoda/immunology ; Copepoda/metabolism ; Ectoparasitic Infestations/immunology ; Ectoparasitic Infestations/parasitology ; Fish Diseases/immunology ; Fish Diseases/parasitology ; Immunity, Cellular ; Leukocytes, Mononuclear/immunology ; Leukotriene B4/immunology ; Salmo salar/immunology
Chemical Substances	Leukotriene B4 (1HGW4DR56D)
Language	English
Publishing date	2020-01-14
Publishing country	England
Document type	Journal Article
ZDB-ID	1067738-0
ISSN	1095-9947 ; 1050-4648
ISSN (online)	1095-9947
ISSN	1050-4648
DOI	10.1016/j.fsi.2020.01.023
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 5917: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED