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  1. Book: The cutaneous lymphoid proliferation

    Magro, Cynthia M. / Crowson, A. Neil / Mihm, Martin C.

    a comprehensive textbook of lymphocytic infiltrates of the skin

    2016  

    Author's details Cynthia M. Magro ; A. Neil Crowson ; Martin C. Mihm
    Keywords Lymphoproliferative disorders ; Skin/Tumors ; Lymphomas
    Subject code 616.99477079
    Language English
    Size VIII, 558 S. : zahlr. Ill., graph. Darst.
    Edition 2. ed.
    Publisher Wiley-Blackwell
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT018719857
    ISBN 978-1-11877-626-1 ; 1-11877-626-7
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Biopsy interpretation of the skin

    Crowson, A. Neil / Magro, Cynthia M. / Mihm, Martin C.

    primary non-lymphoid cutaneous neoplasia

    (Biopsy interpretation series)

    2019  

    Author's details A. Neil Crowson, Cynthia M. Magro, Martin C. Mihm Jr,
    Series title Biopsy interpretation series
    Keywords Skin Neoplasms / diagnosis ; Skin Neoplasms / pathology ; Biopsy / methods
    Language English
    Size ix, 675 Seiten, Illustrationen
    Edition Second edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index ; Zugang zu Online-Ausgabe über Code
    HBZ-ID HT019778330
    ISBN 978-1-4963-6513-2 ; 1-4963-6513-5
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Difficulties in diagnosing dermatophytomas: Analysis of clinical and dermoscopic findings.

    Miller, Rhiannon C / Curtis, Kaya L / Magro, Cynthia M / Lipner, Shari R

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2024  

    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.20020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Psychosocial distress and health status as risk factors for ten-year major adverse cardiac events and mortality in patients with non-obstructive coronary artery disease.

    Mommersteeg, Paula M C / Lodder, Paul / Aarnoudse, Wilbert / Magro, Michael / Widdershoven, Jos W

    International journal of cardiology

    2024  Volume 406, Page(s) 132062

    Abstract: Background: We examined the risk of psychosocial distress, including Type D personality, depressive symptoms, anxiety, positive mood, hostility, and health status fatigue and disease specific and generic quality of life for MACE in patients with non- ... ...

    Abstract Background: We examined the risk of psychosocial distress, including Type D personality, depressive symptoms, anxiety, positive mood, hostility, and health status fatigue and disease specific and generic quality of life for MACE in patients with non-obstructive coronary artery disease (NOCAD).
    Methods: In the Tweesteden mild stenosis (TWIST) study, 546 patients with NOCAD were followed for 10 years to examine the occurrence of cardiac mortality, a major cardiac event, or non-cardiac mortality in the absence of a cardiac event. Cox proportional hazard models were used to examine the impact of psychosocial distress and health status on the occurrence of MACE while adjusting for age, sex, disease severity, and lifestyle covariates.
    Results: In total 19% of the patients (mean age baseline = 61, SD 9 years; 52% women) experienced MACE, with a lower risk for women compared to men. Positive mood (HR 0.97, 95%CI 0.95-1.00), fatigue (HR 1.03, 95%CI 1.00-1.06), and physical limitation (HR 0.99, 95%CI 0.98-1.00) were associated with MACE in adjusted models. No significant interactions between sex and psychosocial factors were present. Depressive symptoms were predictive of MACE, but no longer after adjustment.
    Conclusions: In patients with NOCAD fatigue, low positive mood, and a lower physical limitation score were associated with MACE, without marked sex differences. Type D personality, psychosocial factors, and health status were not predictive of adverse outcomes. Reducing psychosocial distress is a valid intervention goal by itself, though it is less likely to affect MACE in patients with NOCAD.
    Language English
    Publishing date 2024-04-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2024.132062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Microvascular C5b-9 deposition in non-lesional skin in patients with SLE and its correlation with active lupus nephritis: a prospective observational study.

    Anderson, Meghan / Magro, Cynthia / Belmont, H Michael

    Lupus science & medicine

    2023  Volume 10, Issue 2

    Abstract: Objective: Tissue damage in lupus nephritis (LN) is mediated by activation of the classical complement pathway. Complement-mediated upregulation of endothelial cell adhesion molecules is seen in dermal blood vessels of non-lesional skin of patients with ...

    Abstract Objective: Tissue damage in lupus nephritis (LN) is mediated by activation of the classical complement pathway. Complement-mediated upregulation of endothelial cell adhesion molecules is seen in dermal blood vessels of non-lesional skin of patients with active lupus. In diseases with systemic complement activation, extensive microvascular C5b-9 deposition is seen in non-lesional skin. In this study, we assess the presence of systemic complement pathway activation as determined by non-lesional skin microvascular C5b-9 deposition in patients with LN.
    Methods: Eight patients with active LN and eight patients without active LN underwent non-lesional skin biopsies. Using a diaminobenzidine technique, specimens were evaluated for microvascular C5b-9 consistent with systemic complement pathway activation.
    Results: Five of eight patients with active LN and one of eight patients without active LN demonstrated positive C5b-9 staining in non-lesional skin (p=0.04). Positive non-lesional C5b-9 staining has greater specificity, 87.5%, for active LN than pyuria, low complements, elevated double-stranded DNA (dsDNA) and proteinuria. Urine protein creatinine ratio was significantly higher in patients with positive non-lesional C5b-9 deposition (5.18 vs 1.20; p=0.04). C5b-9 deposition was not associated with a higher NIH Activity Index, interstitial fibrosis, dsDNA or lower complements.
    Conclusion: This is the first study to demonstrate evidence in non-lesional skin of microvascular C5b-9 indicative of systemic complement pathway activation in LN. C5b-9 deposition is statistically more common and demonstrated greater specificity than most historical biomarkers for active LN. The findings support a potential role for microvascular C5b-9 assessment in non-lesional skin as a biomarker for LN activity.
    MeSH term(s) Humans ; Lupus Nephritis/complications ; Lupus Nephritis/pathology ; Complement Membrane Attack Complex ; Lupus Erythematosus, Systemic ; Complement System Proteins ; Complement Activation ; Biomarkers
    Chemical Substances Complement Membrane Attack Complex ; Complement System Proteins (9007-36-7) ; Biomarkers
    Language English
    Publishing date 2023-10-24
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2779620-6
    ISSN 2053-8790
    ISSN 2053-8790
    DOI 10.1136/lupus-2023-000996
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: How to assess risk and counsel patients before cardiac surgery: Beyond an age cut-off.

    Sousa Uva, Miguel / Strong, Christopher / Magro, Pedro

    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

    2023  Volume 42, Issue 4, Page(s) 305–306

    MeSH term(s) Humans ; Cardiac Surgical Procedures/adverse effects ; Risk Assessment ; Counseling
    Language Portuguese
    Publishing date 2023-02-02
    Publishing country Portugal
    Document type Journal Article ; Comment
    ZDB-ID 632718-7
    ISSN 2174-2030 ; 0870-2551 ; 0304-4750
    ISSN (online) 2174-2030
    ISSN 0870-2551 ; 0304-4750
    DOI 10.1016/j.repc.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder: A clinical and histologic retrospective cohort study.

    Stephan, Carla / Grossman, Marc E / Magro, Cynthia M

    Clinics in dermatology

    2023  Volume 41, Issue 6, Page(s) 666–679

    Abstract: Clonally restricted, non-epidermotropic, low-grade, CD8-positive T-cell infiltrates of the skin was recognized as a unique form of indolent CD8-positive lymphoproliferative disease in 2007 when it was first called primary cutaneous indolent CD8-positive ... ...

    Abstract Clonally restricted, non-epidermotropic, low-grade, CD8-positive T-cell infiltrates of the skin was recognized as a unique form of indolent CD8-positive lymphoproliferative disease in 2007 when it was first called primary cutaneous indolent CD8-positive lymphoid proliferation. More recently, the designation of primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder has been used. It is unique as a cutaneous lymphoproliferative disorder because of relative uniformity in its clinical presentation and histomorphology. It has been recognized as having an interesting predilection for the ear and acral sites, characteristically presenting as a solitary lesion. The basic morphology is one characterized by a non-epidermotropic, tumefactive infiltrate of well-differentiated, noncerebriform, atypical, small- to intermediate-sized lymphocytes that exhibit a specific phenotype characterized by CD8 and TIA positivity in concert with a distinct perinuclear Golgi staining pattern for CD68. The typical presentation is in the context of a solitary lesion, which can be treated surgically or with local irradiation. We describe in detail two very unusual cases that expand the clinical spectrum of this condition given the non-acral localization, the multiplicity of lesions to involve the trunk and extremities, and, in one case, the stable but recalcitrant course over 30 years. In addition, the second patient developed paraneoplastic dermatomyositis. We also retrospectively review our database for other cases that represent the entity of primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder and review the literature focusing on non-acral cases. Nomenclature evolution from its first recognition in 2007 to the present is discussed.
    MeSH term(s) Humans ; Retrospective Studies ; Skin Neoplasms/pathology ; Lymphoma, T-Cell, Cutaneous ; CD8-Positive T-Lymphocytes ; Lymphoproliferative Disorders
    Language English
    Publishing date 2023-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1064149-x
    ISSN 1879-1131 ; 0738-081X
    ISSN (online) 1879-1131
    ISSN 0738-081X
    DOI 10.1016/j.clindermatol.2023.09.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Acral Fibrochondromyxoid Tumor Presenting as Enlarging Nodule Involving the Distal Fingertip and Hyponychium: A Case Report.

    Miller, Rhiannon C / Magro, Cynthia M / Melnick, Laura E / Lipner, Shari R

    Case reports in dermatology

    2023  Volume 15, Issue 1, Page(s) 56–61

    Abstract: An acral fibrochondromyxoid tumor is a newly described type of benign soft tissue neoplasm that presents as a single nodular lesion on a finger or toe. There has only been one previous report on this tumor, a case series that described the initial ... ...

    Abstract An acral fibrochondromyxoid tumor is a newly described type of benign soft tissue neoplasm that presents as a single nodular lesion on a finger or toe. There has only been one previous report on this tumor, a case series that described the initial pathologic and clinical findings; however, details on clinical history, physical examination, and outcome are unknown. In this report, we describe a case of a 39-year-old male who presented with a painful enlarging mass involving the distal right 3rd finger and hyponychium. Punch biopsy was performed and the lesion was identified as an acral fibrochondromyxoid tumor on microscopic examination. X-ray showed no bony involvement. The tumor was successfully excised with complete resolution of pain symptoms. We discuss the clinical features and immunohistochemistry findings of our case in the context of the current limited knowledge about this very rare tumor.
    Language English
    Publishing date 2023-03-16
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2505300-0
    ISSN 1662-6567
    ISSN 1662-6567
    DOI 10.1159/000529568
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Atrophic papulosis: the wedge-shaped skin necrosis overlays an active lesion.

    Zouboulis, C C / Shapiro, L S / Magro, C M

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2021  Volume 35, Issue 10, Page(s) e672–e674

    Language English
    Publishing date 2021-06-08
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.17377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Erratum to "Small cell lymphocytic variant of marginal zone lymphoma: A distinct form of marginal zone lymphoma derived from naïve B cells as a cutaneous counterpart to the naïve marginal zone lymphoma of splenic origin" [Ann. Diagn. Pathol. 34 (2018) 116-121].

    Magro, Cynthia M / Olson, Luke C

    Annals of diagnostic pathology

    2020  Volume 46, Page(s) 151460

    Language English
    Publishing date 2020-05-22
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 1440011-x
    ISSN 1532-8198 ; 1092-9134
    ISSN (online) 1532-8198
    ISSN 1092-9134
    DOI 10.1016/j.anndiagpath.2020.151460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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