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  1. Article ; Online: Letter to the article by Yunoki et al.

    Zhou, Ling / Jianying, Yang

    Journal of anesthesia

    2023  Volume 38, Issue 1, Page(s) 148

    MeSH term(s) Humans ; Postoperative Nausea and Vomiting ; Sevoflurane ; Propensity Score ; Benzodiazepines
    Chemical Substances remimazolam (7V4A8U16MB) ; Sevoflurane (38LVP0K73A) ; Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2023-11-06
    Publishing country Japan
    Document type Letter ; Comment
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-023-03280-7
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3408: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Branched Proximity Hybridization Assay for the Quantification of Nanoscale Protein-Protein Proximity.

    Yang, Jianying

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2488, Page(s) 35–45

    Abstract: To better quantify the nanoscale protein-protein proximity, we developed a new branched proximity hybridization assay (bPHA). In this assay, oligo-coupled target protein-binding reagents, such as aptamer, nanobody, and antibodies, are used to convert the ...

    Abstract To better quantify the nanoscale protein-protein proximity, we developed a new branched proximity hybridization assay (bPHA). In this assay, oligo-coupled target protein-binding reagents, such as aptamer, nanobody, and antibodies, are used to convert the proximity of target proteins to the proximity of a pair of designed oligos. The closely positioned oligo pair then serve as a template for a maximum of 400-fold linear signal amplification through branched DNA (bDNA). The amplified bPHA signal is recorded and quantified by flow cytometer, providing high throughput, multiplexing, and single-cell resolution for nanoscale protein proximity studies.
    MeSH term(s) DNA/genetics ; Nucleic Acid Hybridization
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2022-03-26
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2277-3_4
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  3. Article: Response of Siberian Cranes (

    Shao, Mingqin / Wang, Jianying / Ding, Hongxiu / Yang, Fucheng

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 2

    Abstract: To assess the Siberian crane ( ...

    Abstract To assess the Siberian crane (
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14020234
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  4. Article: The Physicochemical Properties and Antioxidant Activities of the Hawthorn Pectin Extracted Using Ultra-High Pressure Assisted Acid Extraction (UPAAE).

    Lv, Dihu / Chen, Jianying / Yang, Chun

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 7

    Abstract: This study aims to investigate the positive effects of ultra-high pressure assisted acid extraction (UPAAE) on both physicochemical properties and antioxidant activities of hawthorn pectin. The basic indicators, structure characterization, and ... ...

    Abstract This study aims to investigate the positive effects of ultra-high pressure assisted acid extraction (UPAAE) on both physicochemical properties and antioxidant activities of hawthorn pectin. The basic indicators, structure characterization, and antioxidant activities were measured, which could indicate the disadvantages and advantages among traditional water extraction (WE), acid extraction (AE), and UPAAE. The results show that the hawthorn pectin of UPAAE has a decrease in esterification degree, protein content, and total polyphenols, but has an increase in total galacturonic acid aldehyde compared to the hawthorn pectin of AE. In the Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM) analyses, the hawthorn of UPAAE has typical pectin absorption peaks in the FT-IR spectrum and a distinct layered structure in the SEM surface image. The ion chromatography profiles show that the molar ratio of galacturonic acid to arabinose in the hawthorn pectin of UPAAE increases and 5.50 μg/mg ribose appears compared to the pectin of AE and WE. The high performance gel permeation chromatography (HPGPC) profile indicates that the molecular weight distribution of hawthorn pectin of UPAAE is more concentrated and has the highest molecular weight compared to the pectin of the other two extraction methods. In the vitro antioxidant activity analysis, the pectin of UPAAE exhibits the highest scavenging rate against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals (93.70%), which is close to the scavenging rate of vitamin C (96.30%). These findings demonstrated that UPAAE is a more efficient and environmentally friendly method for pectin extraction from hawthorn. It is also an effective way to enhance its antioxidant activity, which has great application prospects in the food industries.
    Language English
    Publishing date 2024-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13070983
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  5. Article ; Online: Analysis of the effectiveness of cognitive behavioral nursing interventions in the nursing of patients with laryngeal cancer.

    Liu, Jiaqi / Yang, Jianying / Yang, Cuirong / Li, Peipei

    Minerva pediatrics

    2023  Volume 75, Issue 4, Page(s) 637–639

    MeSH term(s) Humans ; Laryngeal Neoplasms/therapy ; Cognitive Behavioral Therapy ; Nursing Homes ; Cognition
    Language English
    Publishing date 2023-02-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062664-X
    ISSN 2724-5780
    ISSN (online) 2724-5780
    DOI 10.23736/S2724-5276.23.07187-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Um IV Zs.161: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Author Correction: Application and configuration analysis of electric muck transfer equipment in plateau railway tunnel: a case study in southwest China.

    Yang, Xiaoxu / Liu, Yuming / Liu, Kai / Wei, Jianying / Hu, Guangzhong / Pei, Shifan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 8639

    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-59431-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Microbial community structure and diversity attached to the periphyton in different urban aquatic habitats.

    Yang, Songnan / Zhou, Huiping / Pang, Zhongzheng / Wang, Yiqun / Chao, Jianying

    Environmental monitoring and assessment

    2024  Volume 196, Issue 5, Page(s) 445

    Abstract: Periphyton is a complex community composed of diverse prokaryotes and eukaryotes; understanding the characteristics of microbial communities within periphyton becomes crucial for biogeochemical cycles and energy dynamics of aquatic ecosystems. To further ...

    Abstract Periphyton is a complex community composed of diverse prokaryotes and eukaryotes; understanding the characteristics of microbial communities within periphyton becomes crucial for biogeochemical cycles and energy dynamics of aquatic ecosystems. To further elucidate the community characteristics of periphyton across varied aquatic habitats, including unpolluted ecologically restored lakes, aquaculture ponds, and areas adjacent to domestic and industrial wastewater treatment plant outfalls, we explored the composition and diversity of prokaryotic and eukaryotic communities in periphyton by employing Illumina MiSeq sequencing. Our findings indicated that the prokaryotic communities were predominantly composed of Proteobacteria (40.92%), Bacteroidota (21.01%), and Cyanobacteria (10.12%), whereas the eukaryotic communities were primarily characterized by the dominance of Bacillariophyta (24.09%), Chlorophyta (20.83%), and Annelida (15.31%). Notably, Flavobacterium emerged as a widely distributed genus among the prokaryotic community. Unclassified_Tobrilidae exhibited higher abundance in unpolluted ecologically restored lakes. Chaetogaster and Nais were enriched in aquaculture ponds and domestic wastewater treatment plant outfall area, respectively, while Surirella and Gomphonema dominated industrial sewage treatment plant outfall area. The alpha diversity of eukaryotes was higher in unpolluted ecologically restored lakes. pH and nitrogen content (
    MeSH term(s) Animals ; Periphyton ; Environmental Monitoring ; Microbiota ; Aquaculture ; Bacteroidetes ; Diatoms ; Oligochaeta
    Language English
    Publishing date 2024-04-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-024-12599-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5186: Show issues

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  8. Article ; Online: Investigation on Bacterial Growth and pH in Milk after the Expiration Date

    Euphoria Yang / Qing Yang / Brett Troemper / Jianying Zhang

    The Scientific World Journal, Vol

    2023  Volume 2023

    Abstract: Food waste is a serious national and global problem. Milk is one of the most frequently wasted food items. This study aims to determine how long postexpiration-pasteurized milk may still be safe to consume and what is the relationship between bacterial ... ...

    Abstract Food waste is a serious national and global problem. Milk is one of the most frequently wasted food items. This study aims to determine how long postexpiration-pasteurized milk may still be safe to consume and what is the relationship between bacterial growth from the milk and time after expiration. The experiments were carried out by incubating milk with agarose gel. The results showed that the bacterial growth was relatively low for at least the first few days after expiration. The more the days passed after the expiration date, the more the bacteria grew from the milk. There was no significant difference in the bacteria colony numbers in the whole milk samples opened either on day 0 or day 5 of expiration. None of the fat-free milk samples collected on the later (1–10) days showed any statistically significant difference in bacterial growth compared to the samples collected on the day after expiration (day 0). The bacterial growth increased with the increasing fat content of the milk. In addition, the rate of bacterial growth from the milk correlated with the acidity of the milk that is measured by pH. No significant sensory changes could be detected in any of the milk samples immediately after opening on the day of expiration or for up to 10 days after expiration when the unopened cartons were kept refrigerated. However, within 24 hours of opening the carton, whole milk that has expired for 6 or more days and 2% milk that has expired for 8 or more days developed a sour taste and mildly pungent smell. This sensory change was accompanied by the formation of lumps and fat-water separation. Fat-free milk samples remained unchanged under the same conditions. The experimental results suggest that whole and 2% skim milk may be safe for consumption up to 5-6 days after expiration. Fat-free milk may be safe for consumption up to 10 days after expiration, possibly longer. This study devised a way to show that milk is still safe for consumption after expiration; it will help reduce food waste.
    Keywords Technology ; T ; Medicine ; R ; Science ; Q
    Subject code 630
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Dissecting the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases

    Xifeng Zheng / Yu Yang / Jianying Chen / Bing Lu

    BMC Public Health, Vol 23, Iss 1, Pp 1-

    Insights from bidirectional mendelian randomization study

    2023  Volume 8

    Abstract: Abstract Objectives Observational studies have revealed that socioeconomic status is associated with cardiovascular health. However, the potential causal effect remains unclear. Hence, we aimed to investigate the causal relationship between household ... ...

    Abstract Abstract Objectives Observational studies have revealed that socioeconomic status is associated with cardiovascular health. However, the potential causal effect remains unclear. Hence, we aimed to investigate the causal relationship between household income status and genetic susceptibility to cardiovascular-related diseases using a bidirectional Mendelian randomization (MR) study. Methods An MR study based on a large-sample cohort of the European population from a publicly available genome-wide association study datasets was conducted using a random-effects inverse-variance weighting model as the main standard. Simultaneously, MR-Egger regression, weighted median, and maximum likelihood estimation were used as supplements. Sensitivity analysis, consisting of a heterogeneity test and horizontal pleiotropy test, was performed using Cochran’s Q, MR-Egger intercept, and MR-PRESSO tests to ensure the reliability of the conclusion. Results The results suggested that higher household income tended to lower the risk of genetic susceptibility to myocardial infarction (OR: 0.503, 95% CI = 0.405–0.625, P < 0.001), hypertension (OR: 0.667, 95% CI = 0.522–0.851, P = 0.001), coronary artery disease (OR: 0.674, 95% CI = 0.509–0.893, P = 0.005), type 2 diabetes (OR: 0.642, 95% CI = 0.464–0.889, P = 0.007), heart failure (OR: 0.825, 95% CI = 0.709–0.960, P = 0.013), and ischemic stroke (OR: 0.801, 95% CI = 0.662–0.968, P = 0.022). In contrast, no association was evident with atrial fibrillation (OR: 0.970, 95% CI = 0.767–1.226, P = 0.798). The reverse MR study suggested a potentially negative trend between heart failure and household income status. A sensitivity analysis verified the reliability of the results. Conclusions The results revealed that the population with higher household income tended to have a lower risk of genetic susceptibility to myocardial infarction and hypertension.
    Keywords Household income status ; Cardiovascular health ; Causal relationship ; Instrumental variable ; Mendelian randomization study ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Investigation on Bacterial Growth and pH in Milk after the Expiration Date.

    Yang, Euphoria / Yang, Qing / Troemper, Brett / Zhang, Jianying

    TheScientificWorldJournal

    2023  Volume 2023, Page(s) 9982886

    Abstract: Food waste is a serious national and global problem. Milk is one of the most frequently wasted food items. This study aims to determine how long postexpiration-pasteurized milk may still be safe to consume and what is the relationship between bacterial ... ...

    Abstract Food waste is a serious national and global problem. Milk is one of the most frequently wasted food items. This study aims to determine how long postexpiration-pasteurized milk may still be safe to consume and what is the relationship between bacterial growth from the milk and time after expiration. The experiments were carried out by incubating milk with agarose gel. The results showed that the bacterial growth was relatively low for at least the first few days after expiration. The more the days passed after the expiration date, the more the bacteria grew from the milk. There was no significant difference in the bacteria colony numbers in the whole milk samples opened either on day 0 or day 5 of expiration. None of the fat-free milk samples collected on the later (1-10) days showed any statistically significant difference in bacterial growth compared to the samples collected on the day after expiration (day 0). The bacterial growth increased with the increasing fat content of the milk. In addition, the rate of bacterial growth from the milk correlated with the acidity of the milk that is measured by pH. No significant sensory changes could be detected in any of the milk samples immediately after opening on the day of expiration or for up to 10 days after expiration when the unopened cartons were kept refrigerated. However, within 24 hours of opening the carton, whole milk that has expired for 6 or more days and 2% milk that has expired for 8 or more days developed a sour taste and mildly pungent smell. This sensory change was accompanied by the formation of lumps and fat-water separation. Fat-free milk samples remained unchanged under the same conditions. The experimental results suggest that whole and 2% skim milk may be safe for consumption up to 5-6 days after expiration. Fat-free milk may be safe for consumption up to 10 days after expiration, possibly longer. This study devised a way to show that milk is still safe for consumption after expiration; it will help reduce food waste.
    MeSH term(s) Animals ; Milk/microbiology ; Refuse Disposal ; Food Preservation/methods ; Bacteria ; Hydrogen-Ion Concentration
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2075968-X
    ISSN 1537-744X ; 1537-744X
    ISSN (online) 1537-744X
    ISSN 1537-744X
    DOI 10.1155/2023/9982886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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