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  1. Article: Transanal Protrusion of Nonischemic Compound Intussusception.

    Gupta, Rahul

    Journal of Indian Association of Pediatric Surgeons

    2022  Volume 27, Issue 4, Page(s) 509–510

    Language English
    Publishing date 2022-07-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_126_21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Propranolol for Vascular Anomalies: Efficacy and Complications in Pediatric Patients.

    Gupta, Rahul

    Journal of Indian Association of Pediatric Surgeons

    2023  Volume 28, Issue 3, Page(s) 194–205

    Abstract: Context: Congenital vascular anomalies are classically subdivided into vascular tumors and vascular malformations. The role of propranolol in the regression of infantile hemangioma (IH), a vascular tumor, is well establishe.: Aims: This study aimed ... ...

    Abstract Context: Congenital vascular anomalies are classically subdivided into vascular tumors and vascular malformations. The role of propranolol in the regression of infantile hemangioma (IH), a vascular tumor, is well establishe.
    Aims: This study aimed to analyze the therapeutic efficacy and complications associated with oral propranolol and adjuvant therapy in the treatment of vascular anomalies.
    Settings and design: A prospective interventional study was undertaken over 10 years duration extending from 2012 to 2022 at a tertiary care teaching institute.
    Materials and methods: All children with cutaneous hemangiomas and lymphatic and venous malformations under 12 years of age, except those with contraindications for administration of propranolol, were included in the study.
    Results: Out of 382 patients, there were 159 males and 223 females (male: female = 1:1.4). The majority (53.66%) were between ≥3 months and 1 year. There were 481 lesions in 382 patients. There were 348 patients with IH, and 11 were congenital hemangiomas (CHs). There were 23 patients with vascular malformations; lymphatic malformation (
    Conclusion: The study validates the use of propranolol hydrochloride as the first-line agent for the treatment of IHs and congenital hemangiomas. It may have an additive role in lymphatic malformations, and venous malformations, as a part of a multimodality treatment approach for vascular malformations.
    Language English
    Publishing date 2023-05-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_117_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: E-agriculture

    Gupta, Rahul

    concepts and applications

    (Icfai books)

    2008  

    Author's details ed. by Rahul Gupta
    Series title Icfai books
    Language English
    Size IX, 190 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Icfai Univ. Press
    Publishing place Hyderabad
    Publishing country India
    Document type Book
    HBZ-ID HT016117217
    ISBN 978-81-314-1596-2 ; 81-314-1596-1
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    098/1241 available for loan (reading room) Freihandmagazin (U1)

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  4. Article ; Online: Could anakinra outmatch dexamethasone/tocilizumab in COVID-19?

    Gupta, Rahul

    Bulletin of the National Research Centre

    2022  Volume 46, Issue 1, Page(s) 100

    Abstract: The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients have similar ...

    Abstract The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients have similar clinical manifestations with patients suffering from certain auto-inflammatory disorders and cytokine storm syndromes. Interestingly, anakinra (blocking both IL-1α and IL-1β) has shown promises in treating these patients with hyperinflammatory disorders, sepsis with multiorgan failures. Another inflammasome, AIM2, involved in production of IL-1 has also been found to be implicated in COVID-19. IL-1β, a known procoagulant, causes induction of tissue factor with increasing vascular endothelial permeability loss ensuing in hypercoagulability-one of the cardinal features of the disease. Hence, anakinra a 17kD recombinant human IL-1 receptor antagonist, used widely in Rheumatoid Arthritis treatments might prove efficacious in attenuating the hyperinflammatory state of the disease. Indeed, some of the controlled clinical trials have shown anakinra to effectively decrease mortality and hospital stay. Targeted cytokine blocking are always preferable in comparison with non-specific blocking (steroids) as it is more restrained with the chances of dampening of systemic immune system being much less. Early cell death and neutrophil migration have been one of the pivotal events in COVID-19 pathogenesis. Hence, suPAR levels which measures IL-1α (necroptosis) and S100A8/A9 (neutrophil migration) can perhaps be a good early biomarker predicting the disease progression. Lastly and importantly, as the vaccines are raised against spike protein and the different variants of concern are known to evade the neutralizing antibodies by varying degrees, it will be deserving to assess anakinra, against the variants of concern as an immunomodulatory drug.
    Language English
    Publishing date 2022-04-13
    Publishing country Germany
    Document type Journal Article
    ISSN 2522-8307
    ISSN (online) 2522-8307
    DOI 10.1186/s42269-022-00781-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Milk curd syndrome with goat's milk

    Rahul Gupta

    Saudi Journal for Health Sciences, Vol 11, Iss 3, Pp 218-

    Revisited

    2022  Volume 221

    Abstract: Milk curd syndrome is an infrequent cause of intestinal obstruction in neonates and early infancy. We are adding to the literature an extremely rare case of milk curd syndrome in a 3-month-old infant who was being fed with goat's milk. A 3-month-old ... ...

    Abstract Milk curd syndrome is an infrequent cause of intestinal obstruction in neonates and early infancy. We are adding to the literature an extremely rare case of milk curd syndrome in a 3-month-old infant who was being fed with goat's milk. A 3-month-old infant presented with features of intestinal obstruction. The patient used to pass a few pellets such as small, firm, white-colored stools after every 2 to 3 days often requiring enema. The baby was fed with goat's milk. Abdominal radiographs suggested large bowel obstruction. The conservative treatment with rectal washes failed. Exploration revealed dilated small bowel with the presence of very dense, inspissated, sticky, and white-colored intraluminal material in the terminal ileum and throughout the colon. Multiple attempts were made to milk the contents distally and finally out of the rectum but failed. A transverse loop colostomy was performed and inspissated milk curds were milked out. The outcome was favorable. The diagnosis of milk curd obstruction should be considered in neonates and infants with signs of the terminal ileum or large bowel obstruction fed with unmodified animal milk, for example, goat's milk (as seen in our case) or formula feeds.
    Keywords formula feed ; goat's milk ; inspissated milk syndrome ; intestinal obstruction ; milk curd syndrome ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article ; Online: Could anakinra outmatch dexamethasone/tocilizumab in COVID-19?

    Rahul Gupta

    Bulletin of the National Research Centre, Vol 46, Iss 1, Pp 1-

    2022  Volume 3

    Abstract: Abstract The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients ... ...

    Abstract Abstract The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients have similar clinical manifestations with patients suffering from certain auto-inflammatory disorders and cytokine storm syndromes. Interestingly, anakinra (blocking both IL-1α and IL-1β) has shown promises in treating these patients with hyperinflammatory disorders, sepsis with multiorgan failures. Another inflammasome, AIM2, involved in production of IL-1 has also been found to be implicated in COVID-19. IL-1β, a known procoagulant, causes induction of tissue factor with increasing vascular endothelial permeability loss ensuing in hypercoagulability-one of the cardinal features of the disease. Hence, anakinra a 17kD recombinant human IL-1 receptor antagonist, used widely in Rheumatoid Arthritis treatments might prove efficacious in attenuating the hyperinflammatory state of the disease. Indeed, some of the controlled clinical trials have shown anakinra to effectively decrease mortality and hospital stay. Targeted cytokine blocking are always preferable in comparison with non-specific blocking (steroids) as it is more restrained with the chances of dampening of systemic immune system being much less. Early cell death and neutrophil migration have been one of the pivotal events in COVID-19 pathogenesis. Hence, suPAR levels which measures IL-1α (necroptosis) and S100A8/A9 (neutrophil migration) can perhaps be a good early biomarker predicting the disease progression. Lastly and importantly, as the vaccines are raised against spike protein and the different variants of concern are known to evade the neutralizing antibodies by varying degrees, it will be deserving to assess anakinra, against the variants of concern as an immunomodulatory drug.
    Keywords Anakinra ; COVID-19 ; IL-1 ; suPAR ; Dexamethasone ; Tocilizumab ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Book ; Online: Quantifying the Uncertainty of Sensitivity Coefficients Computed from Uncertain Compound Admittance Matrix and Noisy Grid Measurements

    Gupta, Rahul

    2023  

    Abstract: The power-flow sensitivity coefficients (PFSCs) are widely used in the power system for expressing linearized dependencies between the controlled (i.e., the nodal voltages, lines currents) and control variables (e.g., active and reactive power injections, ...

    Abstract The power-flow sensitivity coefficients (PFSCs) are widely used in the power system for expressing linearized dependencies between the controlled (i.e., the nodal voltages, lines currents) and control variables (e.g., active and reactive power injections, transformer tap positions, etc.). The PFSCs are often computed by knowing the compound admittance matrix of a given network and the grid states. However, when the branch parameters (or admittance matrix) are inaccurate or known with limited accuracy, the computed PFSCs can not be relied upon. Uncertain PFSCs, when used in control, can lead to infeasible control set-points. In this context, this paper presents a method to quantify the uncertainty of the PFSCs from uncertain branch parameters and noisy grid-state measurements that can be used for formulating safe control schemes. We derive an analytical expression using the error-propagation principle. The developed tool is numerically validated using Monte Carlo simulations.

    Comment: 4 pages, Accepted in IEEE Transactions on Instrumentation & Measurement Letter
    Keywords Electrical Engineering and Systems Science - Systems and Control
    Subject code 621
    Publishing date 2023-12-14
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Article: Newborn Umbilical Cord Stump Myiasis: Report of an Earliest Presentation.

    Sharma, Shyam Bihari / Gupta, Rahul

    Journal of Indian Association of Pediatric Surgeons

    2023  Volume 28, Issue 1, Page(s) 86–87

    Language English
    Publishing date 2023-01-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164528-0
    ISSN 1998-3891 ; 0971-9261
    ISSN (online) 1998-3891
    ISSN 0971-9261
    DOI 10.4103/jiaps.jiaps_125_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Incidental Appendico-Ileal Fistula in a Patient With Adhesive Intestinal Obstruction: A Case Report.

    Gusain, Deepak / Varshney, Rahul / Singh, Arvind / Koli, Jyoti / Gupta, Rahul

    Cureus

    2024  Volume 16, Issue 2, Page(s) e53369

    Abstract: A fistulous communication between the appendix and any viscus is rare. Such fistula is most often acquired due to recurrent appendicitis, cystic fibrosis, Crohn's disease, tuberculosis, and malignancy. Here in, we report a rare case of an appendico-ileal ...

    Abstract A fistulous communication between the appendix and any viscus is rare. Such fistula is most often acquired due to recurrent appendicitis, cystic fibrosis, Crohn's disease, tuberculosis, and malignancy. Here in, we report a rare case of an appendico-ileal fistula incidentally detected during laparotomy for adhesive small bowel obstruction. The fistula was divided, the ileal opening was sutured, and appendectomy was performed. Postoperative recovery was uneventful, with no evidence of malignancy, tuberculosis, or inflammatory bowel disease on the histopathological examination of the appendix.
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Gastric Neuroendocrine Tumor With Cystic Hepatic Metastases Mimicking Hepatic Echinococcosis: A Case Report.

    Gupta, Rahul / Gusain, Deepak / Bansal, Nalini / Varshney, Rahul / Singh, Arvind

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54507

    Abstract: Metastatic gastrointestinal neuroendocrine tumors classically appear as contrast-enhancing lesions on computed tomography. However, in a small percentage of patients, these lesions can be cystic in nature, leading to false diagnoses of benign or ... ...

    Abstract Metastatic gastrointestinal neuroendocrine tumors classically appear as contrast-enhancing lesions on computed tomography. However, in a small percentage of patients, these lesions can be cystic in nature, leading to false diagnoses of benign or infectious lesions such as echinococcosis. Hence, every cystic lesion of the liver must be carefully investigated before making the treatment plan. We report a patient with hematemesis caused by a large gastric ulcer with multiple cystic lesions in the left lobe of the liver abutting the stomach. The liver lesions were misdiagnosed as hepatic echinococcosis, and the patient was started on medical therapy. However, when medical therapy failed, the patient underwent surgical excision and the histopathology showed cystic metastases of a gastric neuroendocrine tumor.
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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