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  1. Book: The Mayo Clinic Cardiac Catheterization Laboratory

    Holmes Jr., David R. / Frye, Robert L. / Ritman, Erik L. / Hagler, Donald J / Munger, Thomas M. / Friedman, Paul A.

    History, Research, and Innovations

    2021  

    Author's details Dr. David R. Holmes, Jr - Dr. Holmes is currently a Professor of Medicine at the Mayo Clinic College of Medicine and a consultant in the Department of Cardiovascular Medicine at Mayo Clinic in Rochester, Minnesota. Dr. Holmes has also been named the Edward W. and Betty Knight Scripps Professor in Cardiovascular Medicine in Honor of Dr. George M. Gura, Jr. He was the Director of the Cardiac Catheterization Laboratory from 1984-2003. He was awarded an Honorary Fellowship of the Royal College of Physicians in Ireland in November 2011. He has received the Distinguished Scientist Award (Clinical Domain) from the American College of Cardiology and the Research Career Achievement Award from the Mayo Graduate School of Medicine. He is a Past President of the American College of Cardiology (ACC) as well as the Society for Cardiac Angiography and Interventions (SCAI). He has received the Herrick Award from the American Heart Association. Dr. Holmes continues to lecture both nationally and
    Keywords Mayo Clinic Catheterization Laboratory ; Cardiovascular Disease ; E.H. Wood ; Stroke prevention ; First AV nodal ablation ; First catheter ablation for ventricular tachycardia ; First Pacemaker ; Electronic and imaging methodology ; Computed Tomography ; congenital heart disease ; Coronary Heart Disease ; hemodynamics ; Indocyanine Green dye ; Cardioversion ; Video densitometry technique ; Right and Left heart catheterization ; Satellite transmission ; New innovation treatment strategies ; The first clinical CT (the Dynamic Spatial Reconstructor) ; Stent Implantation ; Cardiovascular disease ; Congenital heart disease ; Coronary heart disease ; Hemodynamics ; Stent implantation
    Language English
    Size 396 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_12
    Format 160 x 241 x 22
    ISBN 9783030793289 ; 3030793281
    Database PDA

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  2. Article ; Online: In vivo X-Ray Phase Imaging.

    Ritman, Erik L

    EBioMedicine

    2015  Volume 2, Issue 10, Page(s) 1304–1305

    MeSH term(s) Humans ; Imaging, Three-Dimensional ; Phantoms, Imaging ; Synchrotrons ; Tomography, X-Ray Computed ; X-Ray Diffraction ; X-Rays
    Language English
    Publishing date 2015-10
    Publishing country Netherlands
    Document type Comment ; Journal Article
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2015.09.008
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  3. Article ; Online: Earl Wood--a research career noted for development of novel instruments driven by the power of the indicator dilution concept.

    Ritman, Erik L

    Journal of applied physiology (Bethesda, Md. : 1985)

    2014  Volume 117, Issue 9, Page(s) 945–956

    Abstract: During World War 2, Earl Wood was charged with elucidating the biomedical factors in acceleration-induced loss of consciousness experienced by pilots in high-performance aircraft. For this, he developed devices for measurement and recording of blood ... ...

    Abstract During World War 2, Earl Wood was charged with elucidating the biomedical factors in acceleration-induced loss of consciousness experienced by pilots in high-performance aircraft. For this, he developed devices for measurement and recording of blood pressure and tissue blood content. Those data lead to the design and fabrication of successful countermeasures to acceleration-induced loss of consciousness with an inflatable "G-suit" and "M1" breath-holding maneuver. After World War 2, he utilized and modified these instruments and made use of indicator dilution techniques by continuous intracardiac blood sampling to greatly increase the specificity and sensitivity of diagnosis of intracardiac anatomic and functional abnormalities in patients with congenital heart disease. This contributed to the greatly increased success rate of open-heart surgery in the 1950s. In the 1960s, he built on the then recently available video-coupled electronic X-ray image intensifier to develop X-ray fluoroscopy-based recording of indicator dilution signals in all cardiac chambers and surrounding great vessels without the need for placing catheter tips at those locations for blood sampling. However, these blood flow-related data were of limited value, as they were not measured concurrent with myocardial functional demand for perfusion. In the 1970s, he overcame this limitation by developing a high-speed multislice X-ray imaging scanner to provide tomographic images of concurrent dynamic cardiac anatomy and the indicator dilution-based estimates of blood flow distributions. On his retirement at age 70 in 1982, he had accomplished his 2 decade-old goal of the ability to make accurate concurrent, minimally invasive, and indicator dilution-based measurement of cardiovascular structure to function relationships.
    MeSH term(s) Equipment Design/history ; History, 20th Century ; Humans ; Indicator Dilution Techniques/history ; Minnesota ; Research
    Language English
    Publishing date 2014-11-01
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00491.2014
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  4. Book ; Conference proceedings: Symposium: Dynamic Spatial Reconstruction

    Ritman, Erik L.

    [circa 1994]

    1994  

    Title variant Dynamic spatial reconstruction
    Institution Symposium Dynamic Spatial Reconstruction
    Author's details [Erik L. Ritman, guest ed.]
    Keywords Heart / radiography / congresses ; Tomography / methods / congresses ; Image Processing, Computer-Assisted / congresses
    Language English
    Publishing country United States
    Document type Book ; Conference proceedings
    Note In: American journal of cardiac imaging. - ISSN 0887-7971. - 8 (1994), S. 159 - 205
    HBZ-ID HT006412090
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs B 3063 -8- verfügbar in Königswinter Königswinter

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  5. Article: Measurement of enhanced vasa vasorum density in a porcine carotid model using photon counting detector CT.

    Marsh, Jeffrey F / Vercnocke, Andrew J / Rajendran, Kishore / Tao, Shengzhen / Anderson, Jill L / Ritman, Erik L / Leng, Shuai / McCollough, Cynthia H

    Journal of medical imaging (Bellingham, Wash.)

    2023  Volume 10, Issue 1, Page(s) 16001

    Abstract: Purpose: The onset of atherosclerosis is preceded by changes in blood perfusion within the arterial wall due to localized proliferation of the vasa vasorum. The purpose of this study was to quantify these changes in spatial density of the vasa vasorum ... ...

    Abstract Purpose: The onset of atherosclerosis is preceded by changes in blood perfusion within the arterial wall due to localized proliferation of the vasa vasorum. The purpose of this study was to quantify these changes in spatial density of the vasa vasorum using a research whole-body photon-counting detector CT (PCD-CT) scanner and a porcine model.
    Approach: Vasa vasorum angiogenesis was stimulated in the left carotid artery wall of anesthetized pigs (
    Results: The greatest arterial wall enhancement was observed following contrast recirculation. The wall enhancement measurements made over these time points revealed that the enhancement was greater in the injured artery for 13/16 scanned arterial regions. Using an exact Wilcoxon-signed rank test, a significantly increased enhancement ratio was found in injured arteries compared with control arteries (
    Conclusions: Whole-body PCD-CT scanners can be used to detect and quantify the increased perfusion occurring within the porcine carotid arterial wall resulting from an increased density of vasa vasorum.
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article
    ISSN 2329-4302
    ISSN 2329-4302
    DOI 10.1117/1.JMI.10.1.016001
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  6. Article ; Online: Probing the Depth of the Myocardium: Vasculature, Transit Time, and Perfusion Within the Left Ventricular Wall.

    Ritman, Erik L / Vercnocke, A J / Zamir, M

    Annals of biomedical engineering

    2019  Volume 47, Issue 5, Page(s) 1281–1290

    Abstract: The branching architecture of arterial trees traversing the thickness of the left ventricular wall is studied to determine the way in which adequate blood supply is provided to myocardial tissue at different depths within the wall thickness from arterial ...

    Abstract The branching architecture of arterial trees traversing the thickness of the left ventricular wall is studied to determine the way in which adequate blood supply is provided to myocardial tissue at different depths within the wall thickness from arterial trees originating at the epicardial surface. The study is based on micro-CT images of tissue biopsies, coupled with a dedicated vascular tree analysis program. The results show that this combination of methodologies allows a more detailed and much more accurate exploration of the vasculature within the sampled tissue than is possible by histological means. The spatial density of the smallest resolvable "end" arterioles is found to be higher in the sub-endocardial region than in the sub-epicardial region, with vascular branching architecture consistent with a fractal structure. The concept of "transit time" is introduced as an approximate measure of the time it takes bulk flow to reach different regions of the myocardium. Our data suggest that a transit time differential is a major contributor to the equalization of transmural perfusion gradient against unequal distribution of "end' arteriolar density.
    MeSH term(s) Animals ; Heart Ventricles/diagnostic imaging ; Models, Cardiovascular ; Myocardium ; Pericardium/diagnostic imaging ; Pericardium/physiology ; Swine ; X-Ray Microtomography
    Language English
    Publishing date 2019-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 185984-5
    ISSN 1573-9686 ; 0191-5649 ; 0090-6964
    ISSN (online) 1573-9686
    ISSN 0191-5649 ; 0090-6964
    DOI 10.1007/s10439-019-02208-1
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  7. Article ; Online: In vivo X-Ray Phase Imaging

    Erik L. Ritman

    EBioMedicine, Vol 2, Iss 10, Pp 1304-

    2015  Volume 1305

    Keywords Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2015-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
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  8. Article ; Online: Current status of developments and applications of micro-CT.

    Ritman, Erik L

    Annual review of biomedical engineering

    2011  Volume 13, Page(s) 531–552

    Abstract: Use of microscopic computed-tomography (micro-CT) scanning continues to grow in biomedical research. Laboratory-based micro-CT scanners, laboratory-based nano-CT scanners, and integrated micro-CT/SPECT and micro-CT/PET scanners are now manufactured for " ... ...

    Abstract Use of microscopic computed-tomography (micro-CT) scanning continues to grow in biomedical research. Laboratory-based micro-CT scanners, laboratory-based nano-CT scanners, and integrated micro-CT/SPECT and micro-CT/PET scanners are now manufactured for "turn-key" operation by a number of commercial vendors. In recent years a number of technical developments in X-ray sources and X-ray imaging arrays have broadened the utility of micro-CT. Of particular interest are photon-counting and energy-resolving detector arrays. These are being explored to maximize micro-CT image grayscale dynamic range and to further increase image contrast by utilizing the unique spectral attenuation characteristics of individual chemical elements. X-ray phase-shift images may increase contrast resolution and reduce radiation exposure. Although radiation exposure is becoming a concern with the drive for increased spatial and temporal resolution, especially for longitudinal studies, gated scans and limited scan-data-set reconstruction algorithms show great potential for keeping radiation exposure to a minimum.
    MeSH term(s) Animals ; Humans ; Imaging, Three-Dimensional/instrumentation ; Imaging, Three-Dimensional/methods ; Mice ; Microradiography/instrumentation ; Microradiography/methods ; Photons ; Rats ; Spectrometry, X-Ray Emission/instrumentation ; Spectrometry, X-Ray Emission/methods ; Tomography, Emission-Computed, Single-Photon/instrumentation ; Tomography, Emission-Computed, Single-Photon/methods ; Tomography, X-Ray Computed/instrumentation ; Tomography, X-Ray Computed/methods ; X-Rays/adverse effects
    Language English
    Publishing date 2011-07-14
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1448425-0
    ISSN 1545-4274 ; 1523-9829
    ISSN (online) 1545-4274
    ISSN 1523-9829
    DOI 10.1146/annurev-bioeng-071910-124717
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  9. Article ; Online: X-ray phase-based imaging: the third wave.

    Ritman, Erik L

    Academic radiology

    2009  Volume 16, Issue 8, Page(s) 909–910

    MeSH term(s) Equipment Design ; Radiographic Image Enhancement/instrumentation ; Radiographic Image Enhancement/methods ; Radiographic Image Interpretation, Computer-Assisted/instrumentation ; Radiographic Image Interpretation, Computer-Assisted/methods ; Technology Assessment, Biomedical ; X-Ray Diffraction/instrumentation ; X-Ray Diffraction/methods ; X-Ray Diffraction/trends
    Language English
    Publishing date 2009-08
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2009.06.003
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  10. Article: The human cutaneous circulation as a model of generalized microvascular function.

    Ritman, Erik L

    Journal of applied physiology (Bethesda, Md. : 1985)

    2008  Volume 105, Issue 1, Page(s) 373; author reply 389

    MeSH term(s) Capillaries/physiology ; Humans ; Microcirculation/physiology ; Regional Blood Flow/physiology ; Skin/blood supply ; Vascular Diseases/diagnosis ; Vascular Diseases/physiopathology
    Language English
    Publishing date 2008-07
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 8750-7587 ; 0021-8987 ; 0161-7567
    ISSN (online) 1522-1601
    ISSN 8750-7587 ; 0021-8987 ; 0161-7567
    DOI 10.1152/japplphysiol.zdg-8049-vpcomm.2008
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