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Article: Acute kidney injury in pregnant women following SARS-CoV-2 infection: A case report from Iran.

Taghizadieh, Ali / Mikaeili, Haleh / Ahmadi, Majid / Valizadeh, Hamed

2020 Volume 30, Page(s) 101090

Abstract: We reported a 33-year-old female case with novel coronavirus disease 2019 (COVID-19) accompanied by Acute tubular necrosis (ATN). She had a gestational age of 34 weeks. The patient referred to treatment clinic for COVID-19 in Imam Reza hospital of Tabriz ...

Abstract	We reported a 33-year-old female case with novel coronavirus disease 2019 (COVID-19) accompanied by Acute tubular necrosis (ATN). She had a gestational age of 34 weeks. The patient referred to treatment clinic for COVID-19 in Imam Reza hospital of Tabriz (Iran) after having flu-like symptoms. In radiologic assessment, ground glass opacity (GGO) with consolidation was found in upper right lobe. Lopinavir/ritonavir (200mg/50mg) two tablet tow times, Ribavirin 200mg every 6 h, and Oseltamivir 75mg tow times were given for the treatment of COVID-19. The medications used for treatment of pneumonia were Meropenem, Ciprofloxacin, Vancomycin. All doses of medications were administrated by adjusted dose assuming the patient is anephric. Also, a few supplements were also given after ATN development including daily Rocaltrol and Nephrovit (as a multivitamin appropriate for patients with renal failure), Folic acid and Calcium carbonate. The patient is still under ventilator with a Fraction of inspired oxygen (FiO
Keywords	covid19
Language	English
Publishing date	2020-05-13
Publishing country	England
Document type	Case Reports
ZDB-ID	2666110-X
ISSN	2213-0071
ISSN	2213-0071
DOI	10.1016/j.rmcr.2020.101090
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Multiple Phantom Tumor of the Lung: A Complex Appearance Resolving with Appropriate Intervention.

Mikaeili, Haleh / Mehdizadeh Baghbani, Jafar

Tanaffos

2017 Volume 15, Issue 4, Page(s) 243–245

Abstract: The term phantom tumor may be used to describe a well-demarcated opacity resulted from pleural effusion. Phantom tumors are commonly associated with congestive heart failure causing transudative pleural effusion within pulmonary fissures. The figure may ... ...

Abstract	The term phantom tumor may be used to describe a well-demarcated opacity resulted from pleural effusion. Phantom tumors are commonly associated with congestive heart failure causing transudative pleural effusion within pulmonary fissures. The figure may bring about inaccurate invasive diagnostic interventions. We report a heavy smoker patient with multiple phantom tumors in the right lung resolved with medical management. This case report provides records for a timely management of similar patients.
Language	English
Publishing date	2017-04-02
Publishing country	Iran
Document type	Case Reports
ZDB-ID	2233372-1
ISSN	1735-0344
ISSN	1735-0344
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Article ; Online: Acute kidney injury in pregnant women following SARS-CoV-2 infection

Ali Taghizadieh / Haleh Mikaeili / Majid Ahmadi / Hamed Valizadeh

Respiratory Medicine Case Reports, Vol 30, Iss , Pp 101090- (2020)

A case report from Iran

2020

Abstract	We reported a 33-year-old female case with novel coronavirus disease 2019 (COVID-19) accompanied by Acute tubular necrosis (ATN). She had a gestational age of 34 weeks. The patient referred to treatment clinic for COVID-19 in Imam Reza hospital of Tabriz (Iran) after having flu-like symptoms. In radiologic assessment, ground glass opacity (GGO) with consolidation was found in upper right lobe. Lopinavir/ritonavir (200mg/50mg) two tablet tow times, Ribavirin 200mg every 6 h, and Oseltamivir 75mg tow times were given for the treatment of COVID-19. The medications used for treatment of pneumonia were Meropenem, Ciprofloxacin, Vancomycin. All doses of medications were administrated by adjusted dose assuming the patient is anephric. Also, a few supplements were also given after ATN development including daily Rocaltrol and Nephrovit (as a multivitamin appropriate for patients with renal failure), Folic acid and Calcium carbonate. The patient is still under ventilator with a Fraction of inspired oxygen (FiO2) of 60% and Positive end-expiratory pressure (PEEP) of eight. SpO2 is 94% but the patient's ATN problem has been resolved. We started weaning from mechanical ventilator. The patient is conscious with full awareness to time, person and place. The maternal well-being is achieved and her neonate was discharged.
Keywords	Pregnancy ; SARS-CoV-2 ; ATN ; Kidney ; Infection ; Renal involvement ; Diseases of the respiratory system ; RC705-779 ; covid19
Subject code	616
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: NT-Pro-BNP levels during spontaneous breathing test and its association with successful weaning in patients undergoing mechanical ventilation in the Intensive Care Unit

Haleh Mikaeili / Katrin Bioukaghazadeh / Masoud Nazemiyeh / Somaieh Matin

Journal of Research in Clinical Medicine, Vol 8, Iss 1, Pp 45-

Original Article

2020 Volume 45

Abstract: Introduction: Weaning of the patient is one of the important medical challenges. One of the most important causes of failure in weaning is cardiovascular disorders. NT-Pro-BNP is a serum marker for cardiac dysfunction. This study conducted to evaluate ... ...

Abstract	Introduction: Weaning of the patient is one of the important medical challenges. One of the most important causes of failure in weaning is cardiovascular disorders. NT-Pro-BNP is a serum marker for cardiac dysfunction. This study conducted to evaluate the level of NT-Pro-BNP during the spontaneous breathing test (SBT) in patients undergoing mechanical ventilation in ICU and its association with successful weaning. Methods: In this cross-sectional study, we enrolled 42 intubated patients who were admitted to the ICU ward of Imam Reza Hospital and were clinically weaned. After obtaining informed consent, SBT was started for the patient. One and a half hours after SBT onset, a venous blood sample was obtained and the patients were followed for SBT test success and the results were recorded. Patients were extubated in stabilized condition or continued mechanical ventilation if needed. Then Data were analyzed. Results: SBT was successful in 45.2% of patients. 54.8% of patients were male. The most common cause of hospitalization was COPD (35.7%). The mean age of patients with successful SBT was 67.53±6.14 years and in patients with unsuccessful SBT was 68.70±5.44 years. There was a significant difference between NT-Pro-BNP levels half an hour after SBT between two groups of patients with successful (7.15±31.18) and unsuccessful (59.61±196.51) SBT. NT-ProBNP changes before and half an hour after SBT in both groups were statistically significant. Conclusion: NT-Pro-BNP is a predictor criteria of success in weaning in patients and as the level of NT-Pro-BNP increases, the rate of failure in weaning increases.
Keywords	nt-pro-bnp ; spontaneous breath test ; ventilator weaning ; Medicine (General) ; R5-920
Subject code	616
Language	English
Publishing date	2020-12-01T00:00:00Z
Publisher	Tabriz University of Medical Sciences Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Acute kidney injury in pregnant women following SARS-CoV-2 infection

Taghizadieh, Ali / Mikaeili, Haleh / Ahmadi, Majid / Valizadeh, Hamed

Respiratory Medicine Case Reports

A case report from Iran

2020 Volume 30, Page(s) 101090

Keywords	Pulmonary and Respiratory Medicine ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	2666110-X
ISSN	2213-0071
ISSN	2213-0071
DOI	10.1016/j.rmcr.2020.101090
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Etiopathogenesis of Psoriasis from Genetic Perspective: An updated Review.

Babaie, Farhad / Omraninava, Melodi / Gorabi, Armita Mahdavi / Khosrojerdi, Arezou / Aslani, Saeed / Yazdchi, Arsalan / Torkamandi, Shahram / Mikaeili, Haleh / Sathyapalan, Thozhukat / Sahebkar, Amirhossein

Current genomics

2023 Volume 23, Issue 3, Page(s) 163–174

Abstract: Psoriasis is an organ-specific autoimmune disease characterized by the aberrant proliferation and differentiation of keratinocytes, leading to skin lesions. Abnormal immune responses mediated by T cells and dendritic cells and increased production of ... ...

Abstract	Psoriasis is an organ-specific autoimmune disease characterized by the aberrant proliferation and differentiation of keratinocytes, leading to skin lesions. Abnormal immune responses mediated by T cells and dendritic cells and increased production of inflammatory cytokines have been suggested as underlying mechanisms in the pathogenesis of psoriasis. Emerging evidence suggests that there is a heritable basis for psoriatic disorders. Moreover, numerous gene variations have been associated with the disease risk, particularly those in innate and adaptive immune responses and antigen presentation pathways. Herein, this article discusses the genetic implications of psoriatic diseases' etiopathogenesis to develop novel investigative and management options.
Language	English
Publishing date	2023-02-06
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	2033677-9
ISSN	1875-5488 ; 1389-2029
ISSN (online)	1875-5488
ISSN	1389-2029
DOI	10.2174/1389202923666220527111037
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Zs.A 5571: Show issues

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Article: Acute kidney injury in pregnant women following SARS-CoV-2 infection: A case report from Iran

Taghizadieh, Ali / Mikaeili, Haleh / Ahmadi, Majid / Valizadeh, Hamed

Respir Med Case Rep

Abstract	We reported a 33-year-old female case with novel coronavirus disease 2019 (COVID-19) accompanied by Acute tubular necrosis (ATN). She had a gestational age of 34 weeks. The patient referred to treatment clinic for COVID-19 in Imam Reza hospital of Tabriz (Iran) after having flu-like symptoms. In radiologic assessment, ground glass opacity (GGO) with consolidation was found in upper right lobe. Lopinavir/ritonavir (200mg/50mg) two tablet tow times, Ribavirin 200mg every six hours, and Oseltamivir 75mg tow times were given for the treatment of COVID-19. The medications used for treatment of pneumonia were Meropenem, Ciprofloxacin, Vancomycin. All doses of medications were administrated by adjusted dose assuming the patient is anephric. Also, a few supplements were also given after ATN development including daily Rocaltrol and Nephrovit (as a multivitamin appropriate for patients with renal failure), Folic acid and Calcium carbonate. The patient is still under ventilator with a Fraction of inspired oxygen (FiO2) of 60% and Positive end-expiratory pressure (PEEP) of eight. SpO2 is 94% but the patient's ATN problem has been resolved. We started weaning from mechanical ventilator. The patient is conscious with full awareness to time, person and place. The maternal well-being is achieved and her neonate was discharged.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #245355
Database	COVID19

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Article ; Online: The early start of hemoperfusion decreases the mortality rate among severe COVID-19 patients: A preliminary study.

Mikaeili, Haleh / Taghizadieh, Ali / Nazemiyeh, Masoud / Rezaeifar, Parisa / Zununi Vahed, Sepideh / Safiri, Saeid / Ardalan, Mohammadreza / Ansarin, Khalil

Hemodialysis international. International Symposium on Home Hemodialysis

2021 Volume 26, Issue 2, Page(s) 176–182

Abstract: Background: Coronavirus disease-2019 (COVID-19)-related organ failure is partly related to a sepsis-like syndrome and extreme pro-inflammatory cytokine release, named cytokine storm. Therapeutic strategies that prevent the production of or remove the ... ...

Abstract	Background: Coronavirus disease-2019 (COVID-19)-related organ failure is partly related to a sepsis-like syndrome and extreme pro-inflammatory cytokine release, named cytokine storm. Therapeutic strategies that prevent the production of or remove the pro-inflammatory cytokines could potentially be an effective therapy in critically afflicted COVID-19 patients. Methods: In this clinical trial study, from April until June 2020, 68 COVID-19 patients (35 vs. 33 controls) with severe critical symptoms, and PaO Results: Demographic characteristics, the acute physiology, and chronic health evaluation score of both groups were similar (p > 0.05). Importantly, we noticed a significant mortality rate reduction in the perfused group compared with controls (37.1% vs. 63.6%, p = 0.02), this positive effect was stronger among those with a P/F ratio higher than 75 (mortality rate of 84.7% for P/F ratio < 75 vs. 15.4% for P/F ratio ≥ 75, p = 0.02). Conclusions: The results imply that early start of hemoperfusion could be more effective and significantly reduce the mortality rate among COVID-19 patients with critical diseases.
MeSH term(s)	COVID-19/therapy ; Hemoperfusion ; Humans ; Renal Dialysis ; Respiration, Artificial ; SARS-CoV-2
Language	English
Publishing date	2021-12-14
Publishing country	Canada
Document type	Controlled Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2192458-2
ISSN	1542-4758 ; 1492-7535
ISSN (online)	1542-4758
ISSN	1492-7535
DOI	10.1111/hdi.12982
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Zs.A 6091: Show issues

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Article ; Online: NK cells - Dr. Jekyll and Mr. Hyde in autoimmune rheumatic diseases.

Hojjatipour, Tahereh / Aslani, Saeed / Salimifard, Sevda / Mikaeili, Haleh / Hemmatzadeh, Maryam / Gholizadeh Navashenaq, Jamshid / Ahangar Parvin, Elham / Jadidi-Niaragh, Farhad / Mohammadi, Hamed

International immunopharmacology

2022 Volume 107, Page(s) 108682

Abstract: Natural killer (NK) cells belong to innate immune system that are large granular lymphocytes differentiating from the common lymphoid progenitors. These cells were first identified by their functional response against tumor cells and virus-infected cells. ...

Abstract	Natural killer (NK) cells belong to innate immune system that are large granular lymphocytes differentiating from the common lymphoid progenitors. These cells were first identified by their functional response against tumor cells and virus-infected cells. That notwithstanding, NK cells are able to affect both adaptive and innate immune arms and modulate a wide range of immune cells. As a consequence, NK cells are capable of bridging between the innate and adaptive immune responses. The effector cytokines as well as direct cell-cell cytotoxicity by NK cells have been shown to be involved in the regulation of the immune responses and might participate in the etiopathogenesis of several disorders, particularly autoimmune rheumatic diseases (AIRDs), such as Ankylosing spondylitis (AS), Rheumatoid arthritis (RA), Systemic lupus erythematosus (SLE), Behcet's disease (BD), Systemic sclerosis (SSc), and psoriasis. Nonetheless, NK cells demonstrate both harmful and protective functions during autoimmune diseases pathogenesis based on the subset of NK cell as well as disease microenvironment and disease phase or genetic/environmental stimuli. Here in this review, we intend to go through the recent findings in the etiology and pathogenesis of AIRDs and discuss about their clinical potential to be utilized as targets for the sake of therapy in the context of such disorders.
MeSH term(s)	Arthritis, Rheumatoid ; Autoimmune Diseases ; Cytotoxicity, Immunologic ; Humans ; Killer Cells, Natural ; Lupus Erythematosus, Systemic ; Rheumatic Diseases
Language	English
Publishing date	2022-03-05
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2043785-7
ISSN	1878-1705 ; 1567-5769
ISSN (online)	1878-1705
ISSN	1567-5769
DOI	10.1016/j.intimp.2022.108682
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Zs.A 5408: Show issues

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Article ; Online: Vitamin D receptor gene polymorphisms and the risk of the type 1 diabetes: a meta-regression and updated meta-analysis.

Zhai, Na / Bidares, Ramtin / Makoui, Masoud Hassanzadeh / Aslani, Saeed / Mohammadi, Payam / Razi, Bahman / Imani, Danyal / Yazdchi, Mohammad / Mikaeili, Haleh

BMC endocrine disorders

2020 Volume 20, Issue 1, Page(s) 121

Abstract: Background: The association between the polymorphisms in the vitamin D receptor (VDR) gene and the risk of type 1 diabetes mellitus (T1DM) has been evaluated in several studies. However, the findings were inconclusive. Thus, we conducted a meta-analysis ...

Abstract	Background: The association between the polymorphisms in the vitamin D receptor (VDR) gene and the risk of type 1 diabetes mellitus (T1DM) has been evaluated in several studies. However, the findings were inconclusive. Thus, we conducted a meta-analysis to comprehensively evaluate the effect of VDR gene polymorphisms on the risk of T1DM. Methods: All relevant studies reporting the association between VDR gene polymorphisms and susceptibility to T1DM published up to May 2020 were identified by comprehensive systematic database search in ISI Web of Science, Scopus, and PubMed/MEDLINE. Strength of association were assessed by calculating of pooled odds ratios (ORs) and 95% confidence intervals (CIs). The methodological quality of each study was assessed according to the Newcastle-Ottawa Scale. To find the potential sources of heterogeneity, meta-regression and subgroup analysis were also performed. Results: A total of 39 case-control studies were included in this meta-analysis. The results of overall population rejected any significant association between VDR gene polymorphisms and T1DM risk. However, the pooled results of subgroup analysis revealed significant negative and positive associations between FokI and BsmI polymorphisms and T1DM in Africans and Americans, respectively. Conclusions: This meta-analysis suggested a significant association between VDR gene polymorphism and T1DM susceptibility in ethnic-specific analysis.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Child ; Child, Preschool ; Diabetes Mellitus, Type 1/epidemiology ; Diabetes Mellitus, Type 1/genetics ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Receptors, Calcitriol/genetics ; Risk Factors ; Young Adult
Chemical Substances	Receptors, Calcitriol ; VDR protein, human
Language	English
Publishing date	2020-08-08
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ISSN	1472-6823
ISSN (online)	1472-6823
DOI	10.1186/s12902-020-00575-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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