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  1. Article ; Online: Corrigendum to "How do biases in sex ratio and disease characteristics affect the spread of sexually transmitted infections?" [J. Theor. Biol. 527 (2021) 110832].

    Halimubieke, Naerhulan / Pirrie, Alistair / Székely, Tamás / Ashby, Ben

    Journal of theoretical biology

    2023  Volume 571, Page(s) 111545

    Language English
    Publishing date 2023-06-16
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2972-5
    ISSN 1095-8541 ; 0022-5193
    ISSN (online) 1095-8541
    ISSN 0022-5193
    DOI 10.1016/j.jtbi.2023.111545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comments to: "Risk factors for a false negative Ortolani and Barlow examination in developmental dysplasia of the hip" by SHS Tan, JXY Lim, AKS Lim, JHP Hui published in Orthop Traumatol Surg Res. 2023:103796. doi: 10.1016/j.otsr.2023.103796.

    Rehm, Andreas / Thahir, Azeem / Judkins, Nicholas / Hatzantoni, Katerina / Newton, Ayla C / Ashby, Elizabeth

    Orthopaedics & traumatology, surgery & research : OTSR

    2024  , Page(s) 103893

    Language English
    Publishing date 2024-04-22
    Publishing country France
    Document type Letter
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2024.103893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comments on: "Surgical treatment of congenital pseudarthrosis of the clavicle: a series of 10 cases" by M. Payen, N. Mainard, F. Accadbled, J. Sales de Gauzy, A. Abid published in Orthop Traumatol Surg Res 2022:103518.

    Rehm, Andreas / Hatzantoni, Katerina / Linardatou Novak, Pinelopi / Clegg, Rachael / Ashby, Elizabeth

    Orthopaedics & traumatology, surgery & research : OTSR

    2023  Volume 110, Issue 1, Page(s) 103752

    MeSH term(s) Humans ; Pseudarthrosis/surgery ; Clavicle
    Language English
    Publishing date 2023-11-14
    Publishing country France
    Document type Letter
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2023.103752
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: "Changes in the management of pediatric medial humeral epicondyle fractures with and without associated elbow dislocation." Scherer S, Dietzel M, Jordan N, Tsiflikas I, Kirschner HJ, Fuchs J, Lieber J. Injury 2021;52:2257-2264.

    Rehm, Andreas / Kobezda, Tamás / Ong, Joshua C Y / Ashby, Elizabeth

    Injury

    2021  Volume 53, Issue 3, Page(s) 1297–1298

    MeSH term(s) Child ; Elbow/injuries ; Humans ; Humeral Fractures/complications ; Humeral Fractures/surgery ; Humerus ; Joint Dislocations/complications
    Language English
    Publishing date 2021-11-29
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2021.11.059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coevolution of Age-Structured Tolerance and Virulence.

    Buckingham, Lydia J / Ashby, Ben

    Bulletin of mathematical biology

    2024  Volume 86, Issue 6, Page(s) 62

    Abstract: Hosts can evolve a variety of defences against parasitism, including resistance (which prevents or reduces the spread of infection) and tolerance (which protects against virulence). Some organisms have evolved different levels of tolerance at different ... ...

    Abstract Hosts can evolve a variety of defences against parasitism, including resistance (which prevents or reduces the spread of infection) and tolerance (which protects against virulence). Some organisms have evolved different levels of tolerance at different life-stages, which is likely to be the result of coevolution with pathogens, and yet it is currently unclear how coevolution drives patterns of age-specific tolerance. Here, we use a model of tolerance-virulence coevolution to investigate how age structure influences coevolutionary dynamics. Specifically, we explore how coevolution unfolds when tolerance and virulence (disease-induced mortality) are age-specific compared to when these traits are uniform across the host lifespan. We find that coevolutionary cycling is relatively common when host tolerance is age-specific, but cycling does not occur when tolerance is the same across all ages. We also find that age-structured tolerance can lead to selection for higher virulence in shorter-lived than in longer-lived hosts, whereas non-age-structured tolerance always leads virulence to increase with host lifespan. Our findings therefore suggest that age structure can have substantial qualitative impacts on host-pathogen coevolution.
    MeSH term(s) Virulence ; Animals ; Host-Pathogen Interactions ; Mathematical Concepts ; Age Factors ; Biological Evolution ; Models, Biological ; Host-Parasite Interactions/immunology ; Biological Coevolution ; Humans ; Longevity
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 184905-0
    ISSN 1522-9602 ; 0007-4985 ; 0092-8240
    ISSN (online) 1522-9602
    ISSN 0007-4985 ; 0092-8240
    DOI 10.1007/s11538-024-01292-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Conference proceedings ; Online: Design elements for gender-responsive breeding

    Ashby, Jacqueline

    Starting points and unresolved issues

    2022  

    Abstract: Presented by Jacqueline Ashby on 21 September 2017, as part of the webinar 'Design elements ...

    Abstract Presented by Jacqueline Ashby on 21 September 2017, as part of the webinar 'Design elements for gender-responsive breeding'. The webinar was co-organized by the CGIAR Collaborative Platform for Gender Research and the CGIAR Research Program on Roots, Tubers and Bananas.
    Keywords research ; gender ; bananas ; breeding ; roots ; tubers ; elements ; program
    Language English
    Publishing date 2022-08-23T17:35:39Z
    Publisher CGIAR Consortium
    Publishing country fr
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Conference proceedings ; Online: A practical decision checklist for gender-responsive plant and animal breeding

    Ashby, Jacqueline

    2022  

    Abstract: ... of these presentations, given by Jacqueline Ashby. ...

    Abstract This presentation was given during a webinar on May 17, 2018. This is the first of these presentations, given by Jacqueline Ashby.
    Keywords gender ; animal breeding ; breeding ; plant ; animal
    Language English
    Publishing date 2022-08-23T17:35:32Z
    Publisher CGIAR Consortium
    Publishing country fr
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Conference proceedings ; Online: Why isn't gender just about impact?

    Ashby, Jacqueline

    2022  

    Abstract: Presented by Jacqui Ashby, CGIAR Consortium Office at the Joint Pan African Grain Legumes and World ...

    Abstract Presented by Jacqui Ashby, CGIAR Consortium Office at the Joint Pan African Grain Legumes and World Cowpea Conference
    Keywords gender ; legumes ; grain legumes ; grain ; office
    Language English
    Publishing date 2022-08-23T17:35:51Z
    Publisher CGIAR Consortium
    Publishing country fr
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: The Evolution of the Age of Onset of Resistance to Infectious Disease.

    Buckingham, Lydia J / Ashby, Ben

    Bulletin of mathematical biology

    2023  Volume 85, Issue 5, Page(s) 42

    Abstract: Many organisms experience an increase in disease resistance as they age, but the time of life at which this change occurs varies. Increases in resistance are partially due to prior exposure and physiological constraints, but these cannot fully explain ... ...

    Abstract Many organisms experience an increase in disease resistance as they age, but the time of life at which this change occurs varies. Increases in resistance are partially due to prior exposure and physiological constraints, but these cannot fully explain the observed patterns of age-related resistance. An alternative explanation is that developing resistance at an earlier age incurs costs to other life-history traits. Here, we explore how trade-offs with host reproduction or mortality affect the evolution of the onset of resistance, depending on when during the host's life cycle the costs are paid (only when resistance is developing, only when resistant or throughout the lifetime). We find that the timing of the costs is crucial to determining evolutionary outcomes, often making the difference between resistance developing at an early or late age. Accurate modelling of biological systems therefore relies on knowing not only the shape of trade-offs but also when they take effect. We also find that the evolution of the rate of onset of resistance can result in evolutionary branching. This provides an alternative, possible evolutionary history of populations which are dimorphic in disease resistance, where the rate of onset of resistance has diversified rather than the level of resistance.
    MeSH term(s) Humans ; Disease Resistance/genetics ; Age of Onset ; Biological Evolution ; Models, Biological ; Mathematical Concepts ; Communicable Diseases/epidemiology
    Language English
    Publishing date 2023-04-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 184905-0
    ISSN 1522-9602 ; 0007-4985 ; 0092-8240
    ISSN (online) 1522-9602
    ISSN 0007-4985 ; 0092-8240
    DOI 10.1007/s11538-023-01144-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Separation of evolutionary timescales in coevolving species.

    Buckingham, Lydia J / Ashby, Ben

    Journal of theoretical biology

    2023  Volume 579, Page(s) 111688

    Abstract: Many coevolutionary processes, including host-parasite and host-symbiont interactions, involve one species or trait which evolves much faster than the other. Whether or not a coevolutionary trajectory converges depends on the relative rates of ... ...

    Abstract Many coevolutionary processes, including host-parasite and host-symbiont interactions, involve one species or trait which evolves much faster than the other. Whether or not a coevolutionary trajectory converges depends on the relative rates of evolutionary change in the two species, and so current adaptive dynamics approaches generally either determine convergence stability by considering arbitrary (often comparable) rates of evolutionary change or else rely on necessary or sufficient conditions for convergence stability. We propose a method for determining convergence stability in the case where one species is expected to evolve much faster than the other. This requires a second separation of timescales, which assumes that the faster evolving species will reach its evolutionary equilibrium (if one exists) before a new mutation arises in the more slowly evolving species. This method, which is likely to be a reasonable approximation for many coevolving species, both provides straightforward conditions for convergence stability and is less computationally expensive than traditional analysis of coevolution models, as it reduces the trait space from a two-dimensional plane to a one-dimensional manifold. In this paper, we present the theory underlying this new separation of timescales and provide examples of how it could be used to determine coevolutionary outcomes from models.
    MeSH term(s) Animals ; Biological Evolution ; Parasites ; Mutation ; Phenotype ; Host-Parasite Interactions/genetics
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2972-5
    ISSN 1095-8541 ; 0022-5193
    ISSN (online) 1095-8541
    ISSN 0022-5193
    DOI 10.1016/j.jtbi.2023.111688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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