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  1. Article ; Online: Reply: Biopsy Assessment of Oncologic Control 3 Years Following Primary Partial Gland Cryoablation: A Prospective Cohort Study of Men With Intermediate-Risk Prostate Cancer.

    Lepor, Herbert

    The Journal of urology

    2023  Volume 211, Issue 2, Page(s) 322–323

    MeSH term(s) Male ; Humans ; Cryosurgery/adverse effects ; Prospective Studies ; Prostate-Specific Antigen ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/pathology ; Biopsy ; Treatment Outcome
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Legends in Urology V30I06.

    Lepor, Herbert

    The Canadian journal of urology

    2023  Volume 30, Issue 6, Page(s) 11710–11712

    Language English
    Publishing date 2023-12-08
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2064475-9
    ISSN 1195-9479
    ISSN 1195-9479
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  3. Article ; Online: AUTHOR REPLY.

    Lepor, Herbert

    Urology

    2021  Volume 155, Page(s) 129

    Language English
    Publishing date 2021-09-06
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2021.03.056
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  4. Article ; Online: EDITORIAL COMMENT.

    Lepor, Herbert

    Urology

    2019  Volume 133, Page(s) 179

    MeSH term(s) Humans ; Male ; Prostatic Neoplasms ; United Kingdom
    Language English
    Publishing date 2019-05-28
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2019.06.044
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  5. Article: Focal Ablation of Prostate Cancer.

    Lepor, Herbert

    Reviews in urology

    2018  Volume 20, Issue 2, Page(s) 107–111

    Language English
    Publishing date 2018-08-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2108895-0
    ISSN 2153-8182 ; 1523-6161
    ISSN (online) 2153-8182
    ISSN 1523-6161
    DOI 10.3909/riu0812
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  6. Article ; Online: Editorial Comment.

    Lepor, Herbert

    The Journal of urology

    2017  Volume 198, Issue 2, Page(s) 343–344

    MeSH term(s) Humans ; Male ; Medical Oncology ; Photochemotherapy ; Photosensitizing Agents ; Prostatic Neoplasms ; Risk
    Chemical Substances Photosensitizing Agents
    Language English
    Publishing date 2017-05-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2017.03.143
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  7. Article ; Online: 5-Year Outcomes Following Focal Laser Ablation of Prostate Cancer.

    Chao, Brian / Lepor, Herbert

    Urology

    2021  Volume 155, Page(s) 124–129

    Abstract: Objective: To characterize the oncologic outcomes 5 years following focal laser ablation (FLA) of localized prostate cancer.: Methods: 36 men underwent in-bore FLA of prostate cancer at our institution between 2013 and 2015. Follow up included ... ...

    Abstract Objective: To characterize the oncologic outcomes 5 years following focal laser ablation (FLA) of localized prostate cancer.
    Methods: 36 men underwent in-bore FLA of prostate cancer at our institution between 2013 and 2015. Follow up included digital rectal examination and PSA testing, multiparametric MRI, and MR-guided biopsies. The primary outcome of interest was failure-free survival (FFS), defined as avoidance of salvage whole gland treatment, systemic therapy, metastasis, or death from prostate cancer.
    Results: Of the 36 men enrolled, 6 were ultimately lost to follow-up. Of the remaining 30, 25 (83%) have remained free from failure over a median follow-up of 71 months'. Among these patients, 10 (40%) developed in-field recurrence, with 9 undergoing salvage partial gland ablation with FLA, cryotherapy, or high-intensity focused ultrasound. Five patients underwent salvage whole gland or systemic treatment and were thus considered to have failed treatment. Two patients developed metastatic disease, and after receiving radiation and ADT, both currently have undetectable PSA levels. No patients in the cohort died from prostate cancer. Limitations include a small study cohort and lack of standardized surveillance protocols 2 years after treatment.
    Conclusion: FLA for select cases of prostate cancer provides high rates of FFS, defined as freedom from whole gland or systemic treatment, metastasis, or death from prostate cancer. However, in- or out-of-field recurrence is common and often necessitates salvage ablation.
    MeSH term(s) Aged ; Cohort Studies ; Follow-Up Studies ; Humans ; Laser Therapy ; Male ; Neoplasm Metastasis ; Neoplasm Recurrence, Local ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/surgery ; Salvage Therapy/statistics & numerical data
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2021-06-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2021.03.054
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  8. Article ; Online: Surgical Treatment of Prostate Carcinoma.

    Lepor, Herbert

    The Journal of urology

    2016  Volume 197, Issue 2S, Page(s) S41–S42

    MeSH term(s) Carcinoma ; Humans ; Male ; Prostatectomy ; Prostatic Neoplasms/surgery ; Seminal Vesicles
    Language English
    Publishing date 2016-12-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2016.10.084
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  9. Article ; Online: Alpha-blockers for the Treatment of Benign Prostatic Hyperplasia.

    Lepor, Herbert

    The Urologic clinics of North America

    2016  Volume 43, Issue 3, Page(s) 311–323

    Abstract: Over the last 2 decades the evolution of alpha-blockers for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) has been to preserve effectiveness, improve tolerability, and eliminate dose titration. Today, alpha-blockers represent the ...

    Abstract Over the last 2 decades the evolution of alpha-blockers for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) has been to preserve effectiveness, improve tolerability, and eliminate dose titration. Today, alpha-blockers represent the first-line treatment of most men with BPH whereby the primary objective is relief from bothersome LUTS.
    MeSH term(s) Adrenergic alpha-Antagonists/therapeutic use ; Humans ; Lower Urinary Tract Symptoms/drug therapy ; Lower Urinary Tract Symptoms/etiology ; Lower Urinary Tract Symptoms/physiopathology ; Male ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/drug therapy ; Urodynamics/drug effects
    Chemical Substances Adrenergic alpha-Antagonists
    Language English
    Publishing date 2016-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 192293-2
    ISSN 1558-318X ; 0094-0143
    ISSN (online) 1558-318X
    ISSN 0094-0143
    DOI 10.1016/j.ucl.2016.04.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Challenge for Urologists Is to Screen, Detect, and Treat Prostate Cancer "Smarter": Will Ablative Technology Result in Smarter Treatment?

    Lepor, Herbert

    European urology

    2016  Volume 70, Issue 3, Page(s) 456–457

    Language English
    Publishing date 2016-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2016.01.024
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