LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 291

Search options

  1. Book ; Thesis: Einfluss von tageszeitlich definiertem körperlichem Training auf die zirkadiane Blutdruckregulation bei Nachtschichtarbeitern

    Von-Holme Chow, Max / Wenzel, Ulrich / Böger, Rainer H.

    2023  

    Institution Universität Hamburg
    Universität Hamburg / Medizinische Fakultät
    Author's details vorgelegt von: Max Von-Holme Chow ; Prüfungsausschuss, der Vorsitzende: Prof. Dr. Ulrich Wenzel, Prüfungsausschuss, 2. Gutachter: Prof. Dr. Rainer Böger
    Language German
    Size 85 Seiten, Illustrationen, Diagramme
    Publishing place Hamburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Hamburg, 2023
    Note Dissertation angenommen von der Medizinischen Fakultät der Universität Hamburg
    HBZ-ID HT030666261
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2024 E 409 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Conference proceedings ; Thesis: Steigerung der eNOS-Expression im Zellversuch durch pflanzliche Substanzen

    Gromow, Alexander / Böger, Rainer H. / Kodolitsch, Yskert von

    2019  

    Institution Universität Hamburg
    Event/congress Universität Hamburg (MedizinischeFakultät)
    Author's details vorgelegt von: Alexander Gromow ; Prüfungsausschuss, der/die Vorsitzende: Prof. Dr. Rainer Böger, Prüfungsausschuss, zweite/r Gutachter/in: Prof. Dr. Yskert von Kodolitsch
    Language German
    Size VIII, 54 Blätter, Diagramme, 30 cm
    Publishing place Hamburg
    Publishing country Germany
    Document type Book ; Conference proceedings ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Hamburg, 2019
    Note Text Deutsch, Zusammenfassung in deutscher und englischer Sprache ; Literaturverzeichnis: Blatt 44-51
    HBZ-ID HT020696851
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 E 119 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Conference proceedings: Proceedings of the First International Symposium on ADMA as a Cardiovascular Risk Factor

    Böger, Rainer H.

    Hamburg, October 4 - 6, 2002

    (Atherosclerosis : Supplements ; 4,4)

    2003  

    Event/congress International Symposium on ADMA as a Cardiovascular Risk Factor (1, 2002, Hamburg)
    Author's details guest ed. Rainer H. Böger
    Series title Atherosclerosis : Supplements ; 4,4
    Atherosclerosis
    Atherosclerosis ; Supplements
    Collection Atherosclerosis
    Atherosclerosis ; Supplements
    Language English
    Size 65 S. : Ill.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT013890742
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 226 -Suppl.4,4- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Book ; Online ; Thesis: Regulation of the L-Arginine-ADMA-NO pathway in coronary and pulmonary endothelial and alveolar epithelial cells during hypoxia

    Schmidt-Hutten, Lena Verfasser] / [Guse, Andreas H. [Akademischer Betreuer] / Böger, Rainer [Akademischer Betreuer]

    2023  

    Author's details Lena Schmidt-Hutten ; Andreas H. Guse, Rainer Böger
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: The pharmacodynamics of L-arginine.

    Böger, Rainer H

    Alternative therapies in health and medicine

    2014  Volume 20, Issue 3, Page(s) 48–54

    Abstract: L-Arginine is a precursor for nitric oxide (NO) synthesis. NO is a ubiquitous mediator that is formed by a family of enzymes called NO synthases (NOSs). In the brain, NO acts as a neurotransmitter; in the immune system, it acts as a mediator of host ... ...

    Abstract L-Arginine is a precursor for nitric oxide (NO) synthesis. NO is a ubiquitous mediator that is formed by a family of enzymes called NO synthases (NOSs). In the brain, NO acts as a neurotransmitter; in the immune system, it acts as a mediator of host defense; and in the cardiovascular system, it mediates the protective effects of the intact endothelium, acting as a vasodilator and endogenous, antiatherogenic molecule. About 5 g of L-arginine are ingested each day in a normal Western diet. Plasma levels of L-arginine are not significantly reduced in most diseases, except in end-stage renal failure during hemodialysis treatment. Nonetheless, intravenous or dietary (oral) administration of relatively large doses of L-arginine has been shown to result in enhanced NO formation in individuals with impaired endothelial function at baseline. In several controlled clinical trials, long-term administration of L-arginine has been shown to improve the symptoms of cardiovascular disease. However, in other trials, L-arginine was not beneficial, and in a recent study, the authors reported higher mortality for participants receiving L-arginine than for those receiving placebo. Recently, it became clear that endogenous levels of asymmetric dimethylarginine (ADMA), a competitive inhibitor of L-Arginine metabolism by NOS, may determine an individual's response to L-arginine supplementation. L-Arginine appears to exert no effect in individuals with low ADMA levels, whereas in those with high levels, L-arginine restores the L-arginine/ADMA ratio to normal and, thereby, normalizes endothelial function. In conclusion, the effects of L-arginine supplementation on human physiology appear to be multicausal and dose-related. Doses of 3-8 g/d appear to be safe and not to cause acute pharmacologic effects in humans.
    MeSH term(s) Animals ; Arginine/analogs & derivatives ; Arginine/metabolism ; Arginine/pharmacology ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/prevention & control ; Dietary Supplements ; Dose-Response Relationship, Drug ; Endothelium, Vascular/drug effects ; Humans ; Nitric Oxide/biosynthesis ; Nitric Oxide Synthase/metabolism
    Chemical Substances dimethylarginine ; Nitric Oxide (31C4KY9ESH) ; Arginine (94ZLA3W45F) ; Nitric Oxide Synthase (EC 1.14.13.39)
    Language English
    Publishing date 2014-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1225073-9
    ISSN 1078-6791
    ISSN 1078-6791
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4504: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Association of Asymmetric and Symmetric Dimethylarginine with Inflammation in the Population-Based Study of Health in Pomerania.

    Winkler, Martin Sebastian / Bahls, Martin / Böger, Rainer H / Ittermann, Till / Dörr, Marcus / Friedrich, Nele / Schwedhelm, Edzard

    Biomolecules

    2023  Volume 13, Issue 11

    Abstract: The amino acids arginine (Arg), asymmetric (ADMA) and symmetric dimethylarginine (SDMA) are related to nitric oxide (NO) metabolism and potential markers of two different disease entities: cardiovascular disease such as atherosclerosis and systemic ... ...

    Abstract The amino acids arginine (Arg), asymmetric (ADMA) and symmetric dimethylarginine (SDMA) are related to nitric oxide (NO) metabolism and potential markers of two different disease entities: cardiovascular disease such as atherosclerosis and systemic inflammation in critically ill patients with sepsis. Although very different in their pathophysiological genesis, both entities involve the functional integrity of blood vessels. In this context, large population-based data associating NO metabolites with proinflammatory markers, e.g., white blood cell count (WBC), high-sensitivity C-reactive protein (hsCRP), and fibrinogen, or cytokines are sparse. We investigated the association of Arg, ADMA and SDMA with WBC, hsCRP, and fibrinogen in 3556 participants of the Study of Health in Pomerania (SHIP)-TREND study. Furthermore, in a subcohort of 456 subjects, 31 inflammatory markers and cytokines were analyzed. We identified Arg and SDMA to be positively associated with hsCRP (β coefficient 0.010, standard error (SE) 0.002 and 0.298, 0.137, respectively) as well as fibrinogen (β 5.23 × 10
    MeSH term(s) Humans ; C-Reactive Protein ; Arginine/metabolism ; Inflammation ; Fibrinogen ; Cytokines ; Biomarkers
    Chemical Substances symmetric dimethylarginine (49787G1ULV) ; C-Reactive Protein (9007-41-4) ; Arginine (94ZLA3W45F) ; Fibrinogen (9001-32-5) ; Cytokines ; Biomarkers
    Language English
    Publishing date 2023-11-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13111612
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book ; Online ; Thesis: Einfluss von Curcuma (Curcuma longa) und ihren Inhaltsstoffen Curcumin, Bisdemethoxycurcumin, Kaffeesäure, Quercetin und Isoquercitrin auf hormonrezeptorpositive maligne (MCF-7) und benigne (MCF-12A) Mammakarzinomzellen

    Hintze, Oliver Oscar [Verfasser] / Richter, Dagmar-Ulrike [Gutachter] / Böger, Rainer H. [Gutachter] / Fischer, Dagmar-Christiane [Gutachter]

    2023  

    Author's details Oliver Oscar Hintze ; Gutachter: Dagmar-Ulrike Richter, Rainer H. Böger, Dagmar-Christiane Fischer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Rostock
    Publishing place Rostock
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Online ; Thesis: Rolle des endogenen NO-Synthase-Inhibitors ADMA bezüglich verzögerter cerebraler Ischämien bei Patienten nach aneurysmatischer Subarachnoidalblutung

    Seeberger-Steinmeister, Miriam [Verfasser] / Böger, Rainer H. [Akademischer Betreuer]

    2020  

    Author's details Miriam Seeberger-Steinmeister ; Betreuer: Rainer Böger
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Staats- und Universitätsbibliothek Hamburg
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Correction to: Arginine derivatives in atrial fibrillation progression phenotypes.

    Büttner, Petra / Bahls, Martin / Böger, Rainer H / Hindricks, Gerhard / Thiele, Holger / Schwedhelm, Edzard / Kornej, Jelena

    Journal of molecular medicine (Berlin, Germany)

    2021  Volume 99, Issue 12, Page(s) 1829

    Language English
    Publishing date 2021-10-29
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1223802-8
    ISSN 1432-1440 ; 0946-2716
    ISSN (online) 1432-1440
    ISSN 0946-2716
    DOI 10.1007/s00109-021-02147-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Biomarkers of the L-Arginine/Dimethylarginine/Nitric Oxide Pathway in People with Chronic Airflow Obstruction and Obstructive Sleep Apnoea.

    Hannemann, Juliane / Thorarinnsdottir, Elin H / Amaral, André F S / Schwedhelm, Edzard / Schmidt-Hutten, Lena / Stang, Heike / Benediktsdottir, Bryndis / Gunnarsdóttir, Ingibjörg / Gislason, Thórarinn / Böger, Rainer

    Journal of clinical medicine

    2023  Volume 12, Issue 16

    Abstract: Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are common chronic diseases that are associated with chronic and intermittent hypoxemia, respectively. Patients affected by the overlap of COPD and OSA have a ... ...

    Abstract Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are common chronic diseases that are associated with chronic and intermittent hypoxemia, respectively. Patients affected by the overlap of COPD and OSA have a particularly unfavourable prognosis. The L-arginine/nitric oxide (NO) pathway plays an important role in regulating pulmonary vascular function. Asymmetric (ADMA) and symmetric dimethylarginine (SDMA) interfere with NO production.
    Methods: We analysed the serum concentrations of ADMA, SDMA, L-arginine, L-citrulline, and L-ornithine in a large sample of the Icelandic general population together with chronic airflow obstruction (CAO), a key physiological marker of COPD that was assessed by post-bronchodilator spirometry (FEV1/FVC < LLN). OSA risk was determined by the multivariable apnoea prediction (MAP) index.
    Results: 713 individuals were analysed, of whom 78 (10.9%) showed CAO and 215 (30%) had MAP > 0.5. SDMA was significantly higher in individuals with CAO (0.518 [0.461-0.616] vs. 0.494 [0.441-0.565] µmol/L;
    Conclusions: The plasma concentrations of ADMA and SDMA are elevated in COPD patients with concomitant intermittent hypoxaemia. This may account for impaired pulmonary NO production, enhanced pulmonary vasoconstriction, and disease progression.
    Language English
    Publishing date 2023-08-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12165230
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top