Article ; Online: The Challenge: Finding the Most Appropriate Statin and Dose for Each Patient.
The Journal of family practice
2021 Volume 70, Issue 6S, Page(s) S53–S58
Abstract: Key takeaways: • Discontinuing statin therapy results in increased cardiovascular risk. • The nocebo effect is a common reason for perceived statin intolerance. • Statin intolerance is much less commonly reported in clinical trials than in clinical ... ...
Abstract | Key takeaways: • Discontinuing statin therapy results in increased cardiovascular risk. • The nocebo effect is a common reason for perceived statin intolerance. • Statin intolerance is much less commonly reported in clinical trials than in clinical practice, suggesting that patient education and other safeguards employed in clinical trials are important to include in clinical practice. • Several strategies are available that can enable continuation of statin therapy in patients who are truly statin-intolerant. |
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MeSH term(s) | Cholesterol, LDL/blood ; Clinical Decision-Making ; Heart Disease Risk Factors ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Myalgia/chemically induced ; Nocebo Effect |
Chemical Substances | Cholesterol, LDL ; Hydroxymethylglutaryl-CoA Reductase Inhibitors |
Language | English |
Publishing date | 2021-08-25 |
Publishing country | United States |
Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Review |
ZDB-ID | 197883-4 |
ISSN | 1533-7294 ; 0094-3509 |
ISSN (online) | 1533-7294 |
ISSN | 0094-3509 |
DOI | 10.12788/jfp.0224 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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