LIVIVO - Search results -

Search results

Result 1 - 10 of total 195

Search options

Article: COVID-19 and Comorbidities: What Has Been Unveiled by Metabolomics?

Camelo, André Luiz Melo / Zamora Obando, Hans Rolando / Rocha, Isabela / Dias, Aline Cristina / Mesquita, Alessandra de Sousa / Simionato, Ana Valéria Colnaghi

Metabolites

2024 Volume 14, Issue 4

Abstract: The COVID-19 pandemic has brought about diverse impacts on the global population. Individuals with comorbidities were more susceptible to the severe symptoms caused by the virus. Within the crisis scenario, metabolomics represents a potential area of ... ...

Abstract	The COVID-19 pandemic has brought about diverse impacts on the global population. Individuals with comorbidities were more susceptible to the severe symptoms caused by the virus. Within the crisis scenario, metabolomics represents a potential area of science capable of providing relevant information for understanding the metabolic pathways associated with the intricate interaction between the viral disease and previous comorbidities. This work aims to provide a comprehensive description of the scientific production pertaining to metabolomics within the specific context of COVID-19 and comorbidities, while highlighting promising areas for exploration by those interested in the subject. In this review, we highlighted the studies of metabolomics that indicated a variety of metabolites associated with comorbidities and COVID-19. Furthermore, we observed that the understanding of the metabolic processes involved between comorbidities and COVID-19 is limited due to the urgent need to report disease outcomes in individuals with comorbidities. The overlap of two or more comorbidities associated with the severity of COVID-19 hinders the comprehension of the significance of each condition. Most identified studies are observational, with a restricted number of patients, due to challenges in sample collection amidst the emergent situation.
Language	English
Publishing date	2024-03-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662251-8
ISSN	2218-1989
ISSN	2218-1989
DOI	10.3390/metabo14040195
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Dinamismo do arranjo produtivo local de cerâmica vermelha do norte maranhense

JOÃO GONSALO DE MOURA / ANA KARLA GOMES CAMELO

Revista Economia Política do Desenvolvimento, Vol 13, Iss

2022 Volume 30

Abstract: O artigo tem por objetivo analisar a robustez temporal da aglomeração produtiva de cerâmica vermelha presente nos municípios de Itapecuru Mirim e Rosário, no estado do Maranhão, no período de 2010 a 2019. O referencial teórico está assentado na abordagem ...

Abstract	O artigo tem por objetivo analisar a robustez temporal da aglomeração produtiva de cerâmica vermelha presente nos municípios de Itapecuru Mirim e Rosário, no estado do Maranhão, no período de 2010 a 2019. O referencial teórico está assentado na abordagem de arranjos produtivos locais (APLs), tendo em vista tratar-se de uma longeva aglomeração de micro e pequenas empresas que comporta uma gama de elementos exortativos ao desenvolvimento de um APL. Quanto à metodologia, o ensaio pode ser caracterizado como um estudo de caso, recorrendo à análise empírica mediante o emprego de um conjunto de indicadores com a finalidade de revelar indícios a respeito do comportamento da atividade em tela, durante o período proposto. As conclusões apontam para a constatação de que os métodos de produção empregados na região são arcaicos e inoperantes, condizentes com um baixo nível de interatividade entre os diversos atores envolvidos. Constata-se, pois, um ambiente marcado pela paralisação do compartilhamento de conhecimentos e experiências entre empresas, contribuindo assim para perpetuação da condição de aglomeração produtiva e inviabilização da ascensão do ambiente para um contexto de APL.
Keywords	Science ; Q ; Economics as a science ; HB71-74
Language	English
Publishing date	2022-10-01T00:00:00Z
Publisher	Universidade Federal de Alagoas
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: An Efficient Method to Prepare Barcoded cDNA Libraries from Plant Callus for Long-Read Sequencing.

Cordeiro, Daniela / Camelo, Alexandra / Pedrosa, Ana Carolina / Brandão, Inês / Canhoto, Jorge / Espírito Santo, Christophe / Correia, Sandra

Methods and protocols

2023 Volume 6, Issue 2

Abstract: Long-read sequencing methods allow a comprehensive analysis of transcriptomes in identifying full-length transcripts. This revolutionary method represents a considerable breakthrough for non-model species since it allows enhanced gene annotation and gene ...

Abstract	Long-read sequencing methods allow a comprehensive analysis of transcriptomes in identifying full-length transcripts. This revolutionary method represents a considerable breakthrough for non-model species since it allows enhanced gene annotation and gene expression studies when compared to former sequencing methods. However, woody plant tissues are challenging to the successful preparation of cDNA libraries, thus, impairing further cutting-edge sequencing analyses. Here, a detailed protocol for preparing cDNA libraries suitable for high throughput RNA sequencing using Oxford Nanopore Technologies
Language	English
Publishing date	2023-03-15
Publishing country	Switzerland
Document type	Journal Article
ISSN	2409-9279
ISSN (online)	2409-9279
DOI	10.3390/mps6020031
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Evaluation of comparative scenarios from different sites of chestnut production using life cycle assessment (LCA): Case study in the Beira Interior region of Portugal.

Pakpahan, Okta Pringga / Moreira, Liliana / Camelo, Alexandra / Karya, Detri / Martins, Ana Catarina / Gaspar, Pedro Dinis / Santo, Christophe Espírito

Heliyon

2023 Volume 9, Issue 1, Page(s) e12847

Abstract: The evaluation of the environmental impacts of chestnut production in the Beira Interior region (Portugal) is accessed. The comparative life cycle assessment (LCA) was performed with the use of openLCA software with 16 Environmental Footprint (EF) impact ...

Abstract	The evaluation of the environmental impacts of chestnut production in the Beira Interior region (Portugal) is accessed. The comparative life cycle assessment (LCA) was performed with the use of openLCA software with 16 Environmental Footprint (EF) impact categories retrieved from the AGRIBALYSE database. The system boundary was from "cradle-to-farm gate" and the functional unit was 1 ton of chestnut delivered to consumers (only wholesale buyers). The processes model for the production of agricultural machinery, pesticides, fertilizers, and materials was modeled based on surveys and existing literature. The data was gathered from four different production areas: Serra da Estrela, Malcata, Gardunha, and Plateau area. Each site has two selected representative producers inner 250 km
Language	English
Publishing date	2023-01-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e12847
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Knowledge of nursing staff before and after training on incontinence-associated dermatitis.

Ximenes, Raelly Ramos Campos / Chaves, Edna Maria Camelo / Girão, Ana Lívia Araújo / Gonçalves, Maria Helane Rocha Batista / Ferreira, Saionara Leal / Carvalho, Rhanna Emanuela Fontenele Lima de

Revista da Escola de Enfermagem da U S P

2024 Volume 58, Page(s) e20230272

Abstract: Objective: To verify the knowledge of nursing staff before and after training on incontinence-associated dermatitis.: Method: A study before and after an educational intervention carried out with nursing staff from the medical and surgical clinics ... ...

Abstract	Objective: To verify the knowledge of nursing staff before and after training on incontinence-associated dermatitis. Method: A study before and after an educational intervention carried out with nursing staff from the medical and surgical clinics and intensive care unit of the university hospital in June 2023. The training took place over three meetings. Data was collected using a questionnaire administered immediately before and after the training. McNemar's test for dependent samples was used to compare before and after training. Results: 25 nurses and 14 nursing technicians took part. The items that showed statistical significance were related to the identification and correct differentiation of dermatitis associated with incontinence and pressure injury; and the correct way to sanitize the skin. Conclusion: The training of the nursing team made it possible to assess their knowledge of how to identify, prevent and treat incontinence-associated dermatitis.
MeSH term(s)	Humans ; Fecal Incontinence ; Nursing Staff ; Urinary Incontinence ; Intensive Care Units ; Dermatitis/complications
Language	Portuguese
Publishing date	2024-03-29
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2411320-7
ISSN	1980-220X ; 1980-220X
ISSN (online)	1980-220X
ISSN	1980-220X
DOI	10.1590/1980-220X-REEUSP-2023-0272en
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Emergency department contribution to HCV elimination in the Iberian Peninsula.

International journal of emergency medicine

2024 Volume 17, Issue 1, Page(s) 5

Abstract: Background: Undiagnosed cases of hepatitis C virus (HCV) infection result in significant morbidity and mortality, further transmission, and increased public health costs. Testing in emergency departments (EDs) is an opportunity to expand HCV screening. ... ...

Abstract	Background: Undiagnosed cases of hepatitis C virus (HCV) infection result in significant morbidity and mortality, further transmission, and increased public health costs. Testing in emergency departments (EDs) is an opportunity to expand HCV screening. The goal of this project was to increase the proportion of eligible patients screened for HCV in urban areas. Methods: An opportunistic automated HCV screening program was implemented in the EDs of 4 public hospitals in Spain and Portugal at different periods between 2018 and 2023. HCV prevalence was prospectively evaluated, and single-step or reflex testing was used for confirmation in the same sample. Results: More than 90% of the population eligible for testing were screened in the participating centers. We found HCV antibody seroprevalence rates ranging from 0.6 to 3.9%, with between 19 and 53% of viremic individuals. Conclusions: Opportunistic HCV screening in EDs is feasible, does not disrupt ED activities, is highly effective in increasing diagnosis, and contributes to WHO's HCV elimination goals.
Language	English
Publishing date	2024-01-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2411462-5
ISSN	1865-1380 ; 1865-1372
ISSN (online)	1865-1380
ISSN	1865-1372
DOI	10.1186/s12245-023-00570-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Urinary cotinine assessment of maternal smoking and environmental tobacco smoke exposure status and its associations with perinatal outcomes: a cross-sectional birth study

Silva, Ana Inês / Camelo, Alexandra / Madureira, Joana / Reis, Ana Teresa / Machado, Ana Paula / Teixeira, João Paulo / Costa, Carla

Environmental research. 2022 Jan., v. 203

2022

Abstract: Tobacco consumption and environmental tobacco smoke (ETS) exposure remains an important public health concern. Pregnant women require particular attention as active and passive smoking during pregnancy are associated with multiple adverse perinatal ... ...

Abstract	Tobacco consumption and environmental tobacco smoke (ETS) exposure remains an important public health concern. Pregnant women require particular attention as active and passive smoking during pregnancy are associated with multiple adverse perinatal outcomes. This study aimed to biochemically validate self-reported smoking and ETS exposure status among pregnant women, to more precisely ascertain its association with adverse perinatal outcomes. Data refers to 595 pregnant women who sought prenatal care in a public hospital in Porto, Portugal. A standard questionnaire on smoking and ETS-related variables was completed. Urinary cotinine (UC) concentrations were assessed by solid-phase competitive ELISA, in maternal urine samples collected on the day of delivery. The results showed that the optimal UC cut-off value to distinguish smokers from non-smokers and within non-smokers those who were exposed to ETS from those non-exposed in the third trimester of pregnancy was 74.1 ng/mL (sensitivity and specificity of 96.7% and 98.0%, respectively) and 1.6 ng/mL (sensitivity of 66.2% and specificity of 75.7%, respectively). The agreement between maternal self-reported and UC-based smoking status was very good (κ=0.919, p<0.001), but much lower for ETS exposure (κ=0.386, p<0.001). Maternal active smoking in the third trimester of pregnancy was associated with a significant decrease in birth weight, length and head circumference of 157.66 g (95% CI: −245.81, −69.52; p<0.001), 0.78 cm (95% CI: −1.22, −0.34; p=0.001) and 0.39 cm (95% CI: −0.70, −0.07; p=0.016), respectively. Maternal ETS exposure in the third trimester of pregnancy was associated with a non-significant increase in birth weight of 38.37 g (95% CI: −28.91, 105.64; p=0.263). Furthermore, maternal smoking cessation was associated with the increase of approximately 172 g in birth weight (95% CI: 50.00, 293.19). As such, there is an urgent need for increased public health awareness campaigns to encourage smoking cessation during pregnancy, in order to improve perinatal outcomes.
Keywords	birth weight ; cotinine ; head circumference ; hospitals ; pregnancy ; prenatal care ; public health ; questionnaires ; research ; second hand smoke ; second-hand smoke exposure ; tobacco ; urine ; Portugal
Language	English
Dates of publication	2022-01
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2021.111827
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 726: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Third-degree atrioventricular block and pacemaker implantation in a man with severe hemophilia A: A case report.

Camelo, Ricardo Mesquita / Duarte, Bruna Pontes / do Nascimento, Antônio Macedo / Vanderlei, Ana Maria

Journal of arrhythmia

2021 Volume 37, Issue 2, Page(s) 460–461

Abstract: Hemophilia A (HA) is a rare bleeding disorder characterized by reduced factor VIII (FVIII) activity and consequently spontaneous bleeding. Since the introduction of prophylaxis with safer FVIII concentrates, people with HA are ageing. Interestingly, they ...

Abstract	Hemophilia A (HA) is a rare bleeding disorder characterized by reduced factor VIII (FVIII) activity and consequently spontaneous bleeding. Since the introduction of prophylaxis with safer FVIII concentrates, people with HA are ageing. Interestingly, they are developing cardiovascular diseases as their non-hemophilia counterparts. We describe a 48-year-old patient with severe HA who presented a third-degree atrioventricular block. A DDDR pacemaker was implanted under supervision of the Hematology Clinics. There were no adverse events during the procedure. The procedure was safe, and it should be performed under the supervision of a hemophilia expert.
Language	English
Publishing date	2021-02-01
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2696593-8
ISSN	1883-2148 ; 1880-4276
ISSN (online)	1883-2148
ISSN	1880-4276
DOI	10.1002/joa3.12513
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Urinary cotinine assessment of maternal smoking and environmental tobacco smoke exposure status and its associations with perinatal outcomes: a cross-sectional birth study.

Silva, Ana Inês / Camelo, Alexandra / Madureira, Joana / Reis, Ana Teresa / Machado, Ana Paula / Teixeira, João Paulo / Costa, Carla

Environmental research

2021 Volume 203, Page(s) 111827

Abstract	Tobacco consumption and environmental tobacco smoke (ETS) exposure remains an important public health concern. Pregnant women require particular attention as active and passive smoking during pregnancy are associated with multiple adverse perinatal outcomes. This study aimed to biochemically validate self-reported smoking and ETS exposure status among pregnant women, to more precisely ascertain its association with adverse perinatal outcomes. Data refers to 595 pregnant women who sought prenatal care in a public hospital in Porto, Portugal. A standard questionnaire on smoking and ETS-related variables was completed. Urinary cotinine (UC) concentrations were assessed by solid-phase competitive ELISA, in maternal urine samples collected on the day of delivery. The results showed that the optimal UC cut-off value to distinguish smokers from non-smokers and within non-smokers those who were exposed to ETS from those non-exposed in the third trimester of pregnancy was 74.1 ng/mL (sensitivity and specificity of 96.7% and 98.0%, respectively) and 1.6 ng/mL (sensitivity of 66.2% and specificity of 75.7%, respectively). The agreement between maternal self-reported and UC-based smoking status was very good (κ=0.919, p<0.001), but much lower for ETS exposure (κ=0.386, p<0.001). Maternal active smoking in the third trimester of pregnancy was associated with a significant decrease in birth weight, length and head circumference of 157.66 g (95% CI: -245.81, -69.52; p<0.001), 0.78 cm (95% CI: -1.22, -0.34; p=0.001) and 0.39 cm (95% CI: -0.70, -0.07; p=0.016), respectively. Maternal ETS exposure in the third trimester of pregnancy was associated with a non-significant increase in birth weight of 38.37 g (95% CI: -28.91, 105.64; p=0.263). Furthermore, maternal smoking cessation was associated with the increase of approximately 172 g in birth weight (95% CI: 50.00, 293.19). As such, there is an urgent need for increased public health awareness campaigns to encourage smoking cessation during pregnancy, in order to improve perinatal outcomes.
MeSH term(s)	Cotinine ; Cross-Sectional Studies ; Female ; Humans ; Maternal Exposure/statistics & numerical data ; Pregnancy ; Smoking ; Tobacco Smoke Pollution/analysis ; Tobacco Smoke Pollution/statistics & numerical data
Chemical Substances	Tobacco Smoke Pollution ; Cotinine (K5161X06LL)
Language	English
Publishing date	2021-08-05
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2021.111827
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 726: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: In silico structure-based design of peptides or proteins as therapeutic tools for obesity or diabetes mellitus: A protocol for systematic review and meta analysis.

Medeiros, Isaiane / Aguiar, Ana Júlia Felipe Camelo / Fortunato, Wendjilla Medeiros / Teixeira, Ana Francisca Gomes / Oliveira E Silva, Emilly Guedes / Bezerra, Ingrid Wilza Leal / Maia, Juliana Kelly da Silva / Piuvezam, Grasiela / Morais, Ana Heloneida de Araújo

Medicine

2023 Volume 102, Issue 15, Page(s) e33514

Abstract: Background: In silico studies using dynamic simulation or molecular docking have boosted the screening and identification of molecules and/or targets in studies aimed at treating diseases such as obesity and diabetes mellitus, optimizing the development ...

Abstract	Background: In silico studies using dynamic simulation or molecular docking have boosted the screening and identification of molecules and/or targets in studies aimed at treating diseases such as obesity and diabetes mellitus, optimizing the development of new drugs. This study aims to describe a systematic review protocol on peptides and proteins evaluated in silico as potential therapeutic agents for obesity or diabetes mellitus. Methods: This protocol followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols and was registered in the International Prospective Register of Systematic Reviews database (number: CRD42022355540). The databases to be searched will be PubMed, ScienceDirect, Scopus, Web of Science, virtual health library, and EMBASE. It will be included in silico studies that evaluate the simulation by dynamics or molecular docking of proteins or peptides involved in treating obesity or diabetes mellitus. Two independent reviewers will select studies, extract data, and assess methodological quality using the adapted Strengthening the reporting of empirical simulation studies. A narrative synthesis of the included studies will be performed for the systematic reviews. Results: This protocol contemplates the production of 2 systematic reviews to be developed focusing on obesity or diabetes mellitus. Conclusion: The reviews will enable knowledge of peptides and proteins involved in research treating these diseases and will emphasize the importance of in silico studies in this context and for the development of future studies.
MeSH term(s)	Humans ; Molecular Docking Simulation ; Diabetes Mellitus/drug therapy ; Obesity/drug therapy ; Peptides/therapeutic use ; Research Design ; Meta-Analysis as Topic
Chemical Substances	Peptides
Language	English
Publishing date	2023-04-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000033514
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.171: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito