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  1. Article ; Online: Structural adaptation to hyperfiltration defines CKD versus healthy aging.

    Denic, Aleksandar / Rule, Andrew D

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2024  

    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfae063
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    Zs.A 2198: Show issues Location:
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  2. Article ; Online: Removal of Small, Asymptomatic Kidney Stones and Relapse.

    Rule, Andrew D

    The New England journal of medicine

    2022  Volume 387, Issue 19, Page(s) 1818

    MeSH term(s) Humans ; Incidence ; Kidney Calculi/diagnostic imaging ; Kidney ; Recurrence
    Language English
    Publishing date 2022-11-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2212541
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  3. Article: Morphometric analysis of chronicity on kidney biopsy: a useful prognostic exercise.

    Asghar, Muhammad S / Denic, Aleksandar / Rule, Andrew D

    Clinical kidney journal

    2024  Volume 17, Issue 2, Page(s) sfad226

    Abstract: Chronic changes on kidney biopsy specimens include increasing amounts of arteriosclerosis, glomerulosclerosis, interstitial fibrosis and tubular atrophy, enlarged nephron size, and reduced nephron number. These chronic changes are difficult to accurately ...

    Abstract Chronic changes on kidney biopsy specimens include increasing amounts of arteriosclerosis, glomerulosclerosis, interstitial fibrosis and tubular atrophy, enlarged nephron size, and reduced nephron number. These chronic changes are difficult to accurately assess by visual inspection but are reasonably quantified using morphometry. This review describes the various patient populations that have undergone morphometric analysis of kidney biopsies. The common approaches to morphometric analysis are described. The chronic kidney disease outcomes associated with various chronic changes by morphometry are also summarized. Morphometry enriches the characterization of chronicity on a kidney biopsy and this can supplement the pathologist's diagnosis. Artificial intelligence image processing tools are needed to automate the annotations needed for practical morphometric analysis of kidney biopsy specimens in routine clinical care.
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad226
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    Zs.A 6587: Show issues Location:
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  4. Article ; Online: Improved Survival after Acute Kidney Injury: Past and Future.

    Kashani, Kianoush / Rule, Andrew D

    Clinical journal of the American Society of Nephrology : CJASN

    2022  Volume 17, Issue 2, Page(s) 179–181

    MeSH term(s) Acute Kidney Injury/diagnosis ; Acute Kidney Injury/mortality ; Acute Kidney Injury/therapy ; Critical Illness ; Humans
    Language English
    Publishing date 2022-02-08
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.16351221
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  5. Article ; Online: Cystatin C-Based Equation to Estimate GFR without Race and Sex. Reply.

    Pottel, Hans / Delanaye, Pierre / Rule, Andrew D

    The New England journal of medicine

    2023  Volume 388, Issue 18, Page(s) 1722

    MeSH term(s) Humans ; Cystatin C ; Glomerular Filtration Rate ; Renal Insufficiency, Chronic
    Chemical Substances Cystatin C
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2303329
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  6. Article ; Online: Long-term Medical Outcomes of Living Kidney Donors.

    Matas, Arthur J / Rule, Andrew D

    Mayo Clinic proceedings

    2022  Volume 97, Issue 11, Page(s) 2107–2122

    Abstract: Historically, to minimize risks, living kidney donors have been highly selected and healthy. Operative risks are well-defined, yet concern remains about long-term risks. In the general population, even a mild reduction in glomerular filtration rate (GFR) ...

    Abstract Historically, to minimize risks, living kidney donors have been highly selected and healthy. Operative risks are well-defined, yet concern remains about long-term risks. In the general population, even a mild reduction in glomerular filtration rate (GFR) is associated with cardiovascular disease, chronic kidney disease, and end-stage kidney disease (ESKD). However, reduction in GFR in the general population is due to kidney or systemic disease. Retrospective studies comparing donors with matched general population controls have found no increased donor risk. Prospective studies comparing donors with controls (maximum follow-up, 9 years) have reported that donor GFR is stable or increases slightly, whereas GFR decreases in controls. However, these same studies identified metabolic and vascular donor abnormalities. There are a few retrospective studies comparing donors with controls. Each has limitations in selection of the control group, statistical analyses, and/or length of follow-up. One such study reported increased donor mortality; 2 reported a small increase in absolute risk of ESKD. Risk factors for donor ESKD are similar to those in the general population. Postdonation pregnancies are also associated with increased risk of hypertension and preeclampsia. There is a critical need for long-term follow-up studies comparing donors with controls from the same era, geographic area, and socioeconomic status who are healthy, with normal renal function on the date matching the date of donation, and are matched on demographic characteristics with the donors. These data are needed to optimize donor candidate counseling and informed consent.
    MeSH term(s) Pregnancy ; Female ; Humans ; Kidney Transplantation/adverse effects ; Prospective Studies ; Retrospective Studies ; Nephrectomy/adverse effects ; Living Donors ; Glomerular Filtration Rate ; Kidney ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/etiology
    Language English
    Publishing date 2022-10-07
    Publishing country England
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2022.06.013
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  7. Article ; Online: Authors' Reply: Morphometric Approach to Different Nephron Segments.

    Denic, Aleksandar / Fnu, Aperna / Mahesh, Kumar / Rule, Andrew D

    Journal of the American Society of Nephrology : JASN

    2023  Volume 34, Issue 12, Page(s) 2054–2056

    MeSH term(s) Nephrons ; Kidney Tubules, Proximal
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000234
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    Zs.A 3344: Show issues Location:
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  8. Article ; Online: Risk of kidney disease after living kidney donation.

    Matas, Arthur J / Rule, Andrew D

    Nature reviews. Nephrology

    2021  Volume 17, Issue 8, Page(s) 509–510

    MeSH term(s) Humans ; Kidney Diseases/etiology ; Kidney Transplantation ; Renal Insufficiency/etiology ; Risk Factors ; Tissue Donors/statistics & numerical data
    Language English
    Publishing date 2021-02-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2490366-8
    ISSN 1759-507X ; 1759-5061
    ISSN (online) 1759-507X
    ISSN 1759-5061
    DOI 10.1038/s41581-021-00407-5
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    Zs.A 6334: Show issues Location:
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    Zs.MG 107: Show issues

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  9. Article ; Online: Authors' Reply: Urine Metabolomic Versus Standard Chemistry Analysis: What can Metabolomic Analysis Bring to the Treatment and Prevention of Urolithiasis?

    Thongprayoon, Charat / Lieske, John C / Rule, Andrew D / Denic, Aleksandar

    Journal of the American Society of Nephrology : JASN

    2023  Volume 34, Issue 6, Page(s) 1124–1125

    MeSH term(s) Humans ; Urolithiasis/prevention & control ; Urolithiasis/therapy ; Metabolomics
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000138
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  10. Article ; Online: Authors' Reply.

    Denic, Aleksandar / Rule, Andrew D

    Journal of the American Society of Nephrology : JASN

    2020  Volume 32, Issue 2, Page(s) 517–518

    Language English
    Publishing date 2020-12-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2020111615
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