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  1. Article: A two-step machine learning approach to predict S&P 500 bubbles.

    Başoğlu Kabran, Fatma / Ünlü, Kamil Demirberk

    Journal of applied statistics

    2020  Volume 48, Issue 13-15, Page(s) 2776–2794

    Abstract: In this paper, we are interested in predicting the bubbles in the S&P 500 stock market with a two ... the bubbles in the S&P 500 index using a widely recognized right-tailed unit root test. Then, SVM is employed ...

    Abstract In this paper, we are interested in predicting the bubbles in the S&P 500 stock market with a two-step machine learning approach that employs a real-time bubble detection test and support vector machine (SVM). SVM as a nonparametric binary classification technique is already a widely used method in financial time series forecasting. In the literature, a bubble is often defined as a situation where the asset price exceeds its fundamental value. As one of the early warning signals, prediction of bubbles is vital for policymakers and regulators who are responsible to take preemptive measures against the future crises. Therefore, many attempts have been made to understand the main factors in bubble formation and to predict them in their earlier phases. Our analysis consists of two steps. The first step is to identify the bubbles in the S&P 500 index using a widely recognized right-tailed unit root test. Then, SVM is employed to predict the bubbles by macroeconomic indicators. Also, we compare SVM with different supervised learning algorithms by using
    Language English
    Publishing date 2020-09-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476802-1
    ISSN 1360-0532 ; 0266-4763
    ISSN (online) 1360-0532
    ISSN 0266-4763
    DOI 10.1080/02664763.2020.1823947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: High-yield production of active recombinant S. simulans lysostaphin expressed in E. coli in a laboratory bioreactor.

    Duman-Özdamar, Zeynep Efsun / Ünlü, Aişe / Ünal, Hayriye / Woodley, John M / Bi Nay, Barış

    Protein expression and purification

    2020  Volume 177, Page(s) 105753

    Abstract: Staphylococcus aureus (S. aureus), which has developed multidrug resistance, leads ... that lysostaphin is an effective bacteriocin on both commercially available and isolated S. aureus strains ...

    Abstract Staphylococcus aureus (S. aureus), which has developed multidrug resistance, leads to many healthcare-associated infections resulting in significant medical and economic losses. Therefore, the development of new efficient strategies to deal with these bacteria has been gaining importance. Lysostaphin is a peptidoglycan hydrolase that has considerable potential as a bacteriocin. However, there have been few reported optimization and scale-up studies of the lysostaphin bioproduction process. Our preliminary results have revealed that the composition of auto-induction media at 30 °C increases the produced lysostaphin around 10-fold in shake flasks. In this study, achieving higher yields for recombinant lysostaphin in E. coli at a laboratory scale has been the aim, through the use of auto-induction media. Optimized medium composition and fermentation parameters were transferred to a laboratory-scale bioreactor. The tested conditions improved protein yields up to 184 mg/L in a 3 L stirred bioreactor and the productivity was improved 2-fold in comparison to previously published reports. Furthermore, this study also showed that lysostaphin is an effective bacteriocin on both commercially available and isolated S. aureus strains. These results will contribute to future larger-scale production of lysostaphin via the proposed fermentation conditions.
    MeSH term(s) Anti-Bacterial Agents/biosynthesis ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Bioreactors ; Cloning, Molecular ; Culture Media/chemistry ; Culture Media/pharmacology ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Fermentation ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Glucose/metabolism ; Glucose/pharmacology ; Glycerol/metabolism ; Glycerol/pharmacology ; Lysostaphin/biosynthesis ; Lysostaphin/genetics ; Lysostaphin/isolation & purification ; Lysostaphin/pharmacology ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Staphylococcus/genetics ; Staphylococcus/metabolism ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/growth & development
    Chemical Substances Anti-Bacterial Agents ; Culture Media ; Recombinant Proteins ; Lysostaphin (EC 3.4.24.75) ; Glucose (IY9XDZ35W2) ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2020-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1055455-5
    ISSN 1096-0279 ; 1046-5928
    ISSN (online) 1096-0279
    ISSN 1046-5928
    DOI 10.1016/j.pep.2020.105753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A pandemic center’s experience of managing pregnant women with COVID‐19 infection in Turkey

    Sahin, Dilek / Tanacan, Atakan / Erol, Seyit A. / Anuk, Ali T. / Eyi, Elif G.Y. / Ozgu‐ Erdinc, A. Seval / Yucel, Aykan / Keskin, Huseyin L. / Tayman, Cüneyt / Unlu, Serpil / Kirca, Fisun / Dinc, Bedia / San, Ishak / Parpucu, Ü. Murat / Surel, Aziz A. / Moraloglu, Ozlem T.

    International Journal of Gynecology & Obstetrics ; ISSN 0020-7292 1879-3479

    A prospective cohort study

    2020  

    Keywords Obstetrics and Gynaecology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1002/ijgo.13318
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Wernicke’s Encephalopathy in an Acute Myeloid Leukemia Patient

    Muhammet Maden / Yahya Çelik / Ercüment Ünlü

    Turkish Journal of Hematology, Vol 33, Iss 1, Pp 78-

    A Case Study

    2016  Volume 79

    Keywords Thiamine ; Wernicke’s encephalopathy ; Acute myeloid leukemia ; Medicine ; R ; Internal medicine ; RC31-1245 ; Specialties of internal medicine ; RC581-951 ; Diseases of the blood and blood-forming organs ; RC633-647.5
    Publishing date 2016-03-01T00:00:00Z
    Publisher Galenos Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: THE FUTURE OF REGIONAL LEADERSHIP AND TURKEY’S POSITION COMPARED TO THE MIDDLE EASTERN UNDERGRADUATE STUDENTS

    MEHMET ÜNLÜ / TOLGA ELDURMAZ

    International Journal of Geography and Geography Education, Iss 38, Pp 69-

    2018  Volume 90

    Abstract: This research is a quantitative survey to determine the value of the perceptions of “the cause of the chaos in the Middle East is the fact that the western people have broken up the Ottoman State” and “we Turks can provide peace, security in the region” ... ...

    Abstract This research is a quantitative survey to determine the value of the perceptions of “the cause of the chaos in the Middle East is the fact that the western people have broken up the Ottoman State” and “we Turks can provide peace, security in the region” in the Middle East and the viewpoint of the Middle East towards our country. In this context, in order to collect data, while conducting a survey for university students from Middle East countries who come to Turkey to study on undergraduate and graduate degrees, also a literature scanning for ever-changing Turkish foreign policy in the 21st century and regional moves have been made. According to the findings, Middle Eastern students are regarding Turkey, Iran and Saudi Arabia in the forefront as a regional leader. It has been observed that most of the students who have seen Iran and Saudi Arabia as leaders, have argued that the regional leader should be Turkey.
    Keywords Middle East ; Turkey ; Leadership ; Foreign Policy ; Geography. Anthropology. Recreation ; G ; Geography (General) ; G1-922
    Subject code 320
    Language English
    Publishing date 2018-07-01T00:00:00Z
    Publisher Marmara University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Association of Parents’ Body Esteem and Body Mass Index with Children’s Body Esteem and BMI

    Hilal Özcebe / Umut Ece Arslan / Sarp Üner / Özgür Araz / Hande Konsuk Ünlü / Mahmut Yardım / Nazmi Bilir / Terry T-K Huang

    Journal of Pediatric Research, Vol 7, Iss 3, Pp 236-

    A Study from Turkey

    2020  Volume 242

    Abstract: Aim:Childhood obesity is associated with psychosocial and medical comorbidities. Children affected by obesity have significantly lower self-esteem than children with normal weight, and families have an important role in the development of body image and ... ...

    Abstract Aim:Childhood obesity is associated with psychosocial and medical comorbidities. Children affected by obesity have significantly lower self-esteem than children with normal weight, and families have an important role in the development of body image and body dissatisfaction. We aimed to examine the relationship between the body esteem of obese children and their parents’ body esteem and weight status.Materials and Methods:This study was carried out in Ankara, the capital city of Turkey, and was rolled out to 9 to 11-year-old children and their parents in 46 schools (2,066 parent-child dyads). The data were collected via parent and child questionnaires. Anthropometric measurements were conducted by the project team. Four different logistic regression models were performed separately; body esteem and Body Mass Index (BMI) for fathers and sons, fathers and daughters, mothers and sons, and mothers and daughters.Results:Mothers obesity was associated with their daughters’ and their sons’ obesity status. Fathers’ obesity status appears to be positively associated with their sons’ status only but not their daughters’. The body esteem of the obese boys was adversely affected only by their own BMI in the models with their fathers and mothers. Compared to boys, girls were affected adversely by their own BMI, their body esteem, and their mothers’ and fathers’ body esteem.Conclusion:A strong association between both the mothers’ and fathers’ role in the body esteem of daughters was found. Further research should be conducted to better understand the socio-cultural dynamics that may be unique to the development of childhood obesity.
    Keywords bmi ; body esteem ; childhood obesity ; parental relations ; daughter ; sons ; turkey ; Medicine ; R ; Pediatrics ; RJ1-570
    Subject code 796
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Galenos Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Two pathological fractures due to mandibular metastasis, rare in colon cancer; a case report presentation.

    Ünlü, Ufuk / Yildiz, Serkan

    Malawi medical journal : the journal of Medical Association of Malawi

    2023  Volume 35, Issue 1, Page(s) 70–71

    Abstract: We reported on 65 years old patient who has colon cancer and referred to our palliative care center with pain due to enlarging metastatic mass on the dorsal of the right hand. She had swelling and numbness on her jaw. Computed tomography (CT) scan was ... ...

    Abstract We reported on 65 years old patient who has colon cancer and referred to our palliative care center with pain due to enlarging metastatic mass on the dorsal of the right hand. She had swelling and numbness on her jaw. Computed tomography (CT) scan was performed for mandible imaging and two pathologic fractures were detected on the right corpus and right condyle of the mandible. Clinicians should consider possible metastases for terminal stage cancer patients.
    MeSH term(s) Female ; Humans ; Aged ; Mandibular Neoplasms/diagnostic imaging ; Mandibular Neoplasms/pathology ; Mandibular Neoplasms/secondary ; Fractures, Spontaneous/pathology ; Mandible/pathology ; Colonic Neoplasms/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-12-21
    Publishing country Malawi
    Document type Case Reports
    ISSN 1995-7270 ; 1995-7262
    ISSN (online) 1995-7270
    ISSN 1995-7262
    DOI 10.4314/mmj.v35i1.11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Right ventriculo-arterial coupling assessed by right ventricular strain is a superior predictor of clinical outcome in patients with pulmonary arterial hypertension.

    Ünlü, Serkan / Voigt, Jens-Uwe

    European heart journal. Cardiovascular Imaging

    2023  Volume 24, Issue 3, Page(s) e53

    MeSH term(s) Humans ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/physiopathology ; Hypertension, Pulmonary/diagnostic imaging ; Hypertension, Pulmonary/physiopathology ; Systole
    Language English
    Publishing date 2023-01-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2638345-7
    ISSN 2047-2412 ; 2047-2404
    ISSN (online) 2047-2412
    ISSN 2047-2404
    DOI 10.1093/ehjci/jeac266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The role of left atrial strain in Heart Failure with preserved ejection fraction.

    Seçkin Göbüt, Özden / Ünlü, Serkan

    The international journal of cardiovascular imaging

    2023  Volume 40, Issue 1, Page(s) 79–80

    MeSH term(s) Humans ; Stroke Volume ; Predictive Value of Tests ; Heart Failure/diagnostic imaging ; Heart Failure/therapy ; Ventricular Function, Left ; Heart Atria/diagnostic imaging
    Language English
    Publishing date 2023-11-11
    Publishing country United States
    Document type Letter
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-023-03000-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Strain Echocardiography in Myocarditis with preserved left ventricular function.

    Seçkin Göbüt, Özden / Ünlü, Serkan

    The international journal of cardiovascular imaging

    2023  Volume 39, Issue 12, Page(s) 2463–2464

    MeSH term(s) Humans ; Ventricular Function, Left ; Myocarditis/diagnostic imaging ; Predictive Value of Tests ; Echocardiography ; Stroke Volume ; Ventricular Dysfunction, Left/diagnostic imaging
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Letter
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-023-02945-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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