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  1. Article ; Online: Don Poldermans MD PhD, replies to European heart journal editorial.

    Poldermans, Don

    European heart journal

    2013  Volume 34, Issue 23, Page(s) 1698

    MeSH term(s) Science/standards ; Scientific Misconduct/ethics ; Trust
    Language English
    Publishing date 2013-06
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
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    Zs.A 1563: Show issues Location:
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  2. Article ; Online: Scientific fraud or a rush to judgment?

    Poldermans, Don

    The American journal of medicine

    2013  Volume 126, Issue 4, Page(s) e5–6

    MeSH term(s) Adrenergic beta-Antagonists/administration & dosage ; Cardiovascular Diseases/prevention & control ; Humans ; Intraoperative Complications/prevention & control ; Perioperative Care/methods ; Postoperative Complications/prevention & control ; Scientific Misconduct
    Chemical Substances Adrenergic beta-Antagonists
    Language English
    Publishing date 2013-04
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2012.10.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Statins and noncardiac surgery: current evidence and practical considerations.

    Poldermans, Don

    Cleveland Clinic journal of medicine

    2009  Volume 76 Suppl 4, Page(s) S79–83

    Abstract: Vascular surgery is associated with a high risk of perioperative morbidity and mortality that is partly attributable to inflammatory stress induced by the surgical procedure. Preoperative initiation of a long-acting statin is a strategy intended to ... ...

    Abstract Vascular surgery is associated with a high risk of perioperative morbidity and mortality that is partly attributable to inflammatory stress induced by the surgical procedure. Preoperative initiation of a long-acting statin is a strategy intended to reduce the inflammatory stress response and the excess risk associated with vascular surgery. The Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echo III demonstrated significant reductions in perioperative myocardial ischemia and the composite end point of myocardial infarction or cardiovascular death with extended-release fluvastatin (relative to placebo) initiated 30 days prior to vascular surgery. These benefits were achieved with no increase in liver dysfunction, evidence of myopathy, or other side effects. Observational data suggest that perioperative statin use is associated with improved recovery from acute kidney injury after high-risk vascular surgery and with improved long-term survival in patients undergoing such surgery.
    MeSH term(s) C-Reactive Protein ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Inflammation ; Interleukin-6 ; Oxidative Stress ; Perioperative Care/adverse effects ; Postoperative Complications/chemically induced ; Risk Assessment ; Risk Factors ; Risk Reduction Behavior
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Interleukin-6 ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2009-11
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 639116-3
    ISSN 1939-2869 ; 0891-1150
    ISSN (online) 1939-2869
    ISSN 0891-1150
    DOI 10.3949/ccjm.76.s4.13
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  4. Article ; Online: European Society of Cardiology 2009 guidelines for preoperative cardiac risk assessment and perioperative cardiac management in noncardiac surgery: key messages for clinical practice.

    Hoeks, Sanne E / Poldermans, Don

    Polskie Archiwum Medycyny Wewnetrznej

    2010  Volume 120, Issue 7-8, Page(s) 294–299

    Abstract: Patients undergoing noncardiac surgery are at risk of adverse perioperative and long-term outcome. When considering a patient for noncardiac surgery, a careful preoperative clinical risk evaluation and subsequent risk-reduction strategies are essential ... ...

    Abstract Patients undergoing noncardiac surgery are at risk of adverse perioperative and long-term outcome. When considering a patient for noncardiac surgery, a careful preoperative clinical risk evaluation and subsequent risk-reduction strategies are essential to reduce postoperative complications. To assist physicians with decision making, clinical guidelines are developed. The aim of clinical guidelines is to improve patient care by providing recommendations about appropriate healthcare in specific circumstances. Development of clinical guidelines is an important component in improving the quality of care. By translating the best available scientific evidence into specific recommendations, guidelines can serve as a useful tool to achieve effective and efficient patient care. In 2009, the first European Society of Cardiology guidelines on perioperative care were developed. This decisionmaking process integrates clinical markers, early coronary evaluation, functional capacity, and the type of surgery involved.
    MeSH term(s) Cardiovascular Diseases/complications ; Humans ; Perioperative Care/standards ; Practice Guidelines as Topic ; Preoperative Care/standards ; Risk Assessment ; Risk Factors ; Societies, Medical
    Language English
    Publishing date 2010-07
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
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    Zs.A 360: Show issues Location:
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  5. Article ; Online: Screening value of N-terminal pro-B-type natriuretic peptide as a predictor of perioperative cardiac events after noncardiac surgery.

    Goei, Dustin / Poldermans, Don

    Future cardiology

    2010  Volume 6, Issue 5, Page(s) 603–609

    Abstract: Preoperative cardiac risk assessment is the cornerstone of rationale perioperative management that guides invasive surgical interventions. In addition to clinical risk factors, a simple screening biomarker would be useful for identifying those surgical ... ...

    Abstract Preoperative cardiac risk assessment is the cornerstone of rationale perioperative management that guides invasive surgical interventions. In addition to clinical risk factors, a simple screening biomarker would be useful for identifying those surgical patients who might benefit from additional cardiac testing or therapeutic interventions. Preoperative plasma levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) are predictors of cardiac events after noncardiac surgery. NT–proBNP is synthesized in the ventricular myocardium in response to ventricular wall stress. To further increase the diagnostic accuracy of NT-proBNP for preoperative screening, it is important to identify confounding factors that influence NT-proBNP levels and their interaction with identifying risks for adverse cardiac events. Moreover, until now the available data from previous studies has been unable to consistently recognize the optimal discriminatory threshold for NT-proBNP. Currently, the ongoing DECREASE-VI study is conducted to evaluate whether current preoperative risk stratification can be improved by incorporating NT-proBNP measurements.
    MeSH term(s) Age Factors ; Anemia ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; General Surgery ; Humans ; Intraoperative Complications/blood ; Intraoperative Complications/prevention & control ; Myocardium ; Natriuretic Peptide, Brain ; Obesity ; Peptide Fragments ; Postoperative Complications/blood ; Postoperative Complications/prevention & control ; Predictive Value of Tests ; Preoperative Care/methods ; Prognosis ; Risk Assessment ; Risk Factors ; Sex Factors
    Chemical Substances Peptide Fragments ; pro-brain natriuretic peptide (1-76) ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2010-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2274267-0
    ISSN 1744-8298 ; 1479-6678
    ISSN (online) 1744-8298
    ISSN 1479-6678
    DOI 10.2217/fca.10.78
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  6. Article ; Online: The experts debate: perioperative beta-blockade for noncardiac surgery--proven safe or not?

    Poldermans, Don / Devereaux, P J

    Cleveland Clinic journal of medicine

    2009  Volume 76 Suppl 4, Page(s) S84–92

    Abstract: ... here by two experts in the field-Dr. Don Poldermans and Dr. P. J. Devereaux (co-principal investigator ...

    Abstract Guidelines on perioperative management of patients undergoing noncardiac surgery recommend the use of prophylactic perioperative beta-blockers in high-risk patients who are not already taking them, and their continuance in patients on chronic beta-blockade prior to surgery. These recommendations were challenged recently by results of the Perioperative Ischemic Evaluation (POISE), a large randomized trial of extended-release metoprolol succinate started immediately before noncardiac surgery in patients at high risk for atherosclerotic disease. While metoprolol significantly reduced myocardial infarctions relative to placebo in POISE, it also was associated with significant excesses of both stroke and mortality. The merits and limitations of POISE and its applicability in light of other trials of perioperative beta-blockade are debated here by two experts in the field-Dr. Don Poldermans and Dr. P. J. Devereaux (co-principal investigator of POISE).
    MeSH term(s) Adrenergic beta-Antagonists/administration & dosage ; Adrenergic beta-Antagonists/adverse effects ; Adrenergic beta-Antagonists/therapeutic use ; Antihypertensive Agents/administration & dosage ; Antihypertensive Agents/therapeutic use ; Humans ; Hypotension ; Metoprolol/administration & dosage ; Metoprolol/therapeutic use ; Myocardial Infarction/drug therapy ; Myocardial Infarction/prevention & control ; Perioperative Care/methods ; Risk Assessment ; Surgical Procedures, Operative/methods ; Time Factors
    Chemical Substances Adrenergic beta-Antagonists ; Antihypertensive Agents ; Metoprolol (GEB06NHM23)
    Language English
    Publishing date 2009-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639116-3
    ISSN 1939-2869 ; 0891-1150
    ISSN (online) 1939-2869
    ISSN 0891-1150
    DOI 10.3949/ccjm.76.s4.14
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  7. Article ; Online: Beta blockers in non-cardiac surgery: haemodynamic data needed.

    Boersma, Eric / Poldermans, Don

    Lancet (London, England)

    2008  Volume 372, Issue 9654, Page(s) 1930–1932

    MeSH term(s) Adrenergic beta-Antagonists/pharmacology ; Adrenergic beta-Antagonists/therapeutic use ; Hemodynamics/drug effects ; Humans ; Intraoperative Care/statistics & numerical data ; Intraoperative Complications/mortality ; Intraoperative Complications/prevention & control ; Myocardial Infarction/mortality ; Myocardial Infarction/prevention & control ; Randomized Controlled Trials as Topic ; Risk Assessment ; Stroke/prevention & control
    Chemical Substances Adrenergic beta-Antagonists
    Language English
    Publishing date 2008-12-06
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(08)61623-2
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  8. Article ; Online: Perioperative beta blockade: where do we go from here?

    Fleisher, Lee A / Poldermans, Don

    Lancet (London, England)

    2008  Volume 371, Issue 9627, Page(s) 1813–1814

    MeSH term(s) Adrenergic beta-Antagonists/adverse effects ; Adrenergic beta-Antagonists/therapeutic use ; Coronary Disease/drug therapy ; Humans ; Hypotension/chemically induced ; Intraoperative Care ; Intraoperative Complications/chemically induced ; Metoprolol/adverse effects ; Metoprolol/therapeutic use ; Risk Factors
    Chemical Substances Adrenergic beta-Antagonists ; Metoprolol (GEB06NHM23)
    Language English
    Publishing date 2008-05-31
    Publishing country England
    Document type Comment ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(08)60662-5
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  9. Article ; Online: Can tissue Doppler imaging detect myocardial viability in patients with left ventricular dysfunction?

    Bax, Jeroen J / Poldermans, Don

    Nature clinical practice. Cardiovascular medicine

    2007  Volume 4, Issue 12, Page(s) 644–645

    Language English
    Publishing date 2007-12
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2177710-X
    ISSN 1743-4300 ; 1743-4297
    ISSN (online) 1743-4300
    ISSN 1743-4297
    DOI 10.1038/ncpcardio1031
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  10. Article ; Online: European Society of Cardiology 2009 guidelines for preoperative cardiac risk assessment and perioperative cardiac management in noncardiac surgery. Key messages for clinical practice

    Sanne E. Hoeks / Don Poldermans

    Polish Archives of Internal Medicine, Vol 120, Iss 7-8, Pp 294-

    2010  Volume 299

    Abstract: Patients undergoing noncardiac surgery are at risk of adverse perioperative and long-term outcome. When considering a patient for noncardiac surgery, a careful preoperative clinical risk evaluation and subsequent risk-reduction strategies are essential ... ...

    Abstract Patients undergoing noncardiac surgery are at risk of adverse perioperative and long-term outcome. When considering a patient for noncardiac surgery, a careful preoperative clinical risk evaluation and subsequent risk-reduction strategies are essential to reduce postoperative complications. To assist physicians with decision making, clinical guidelines are developed. The aim of clinical guidelines is to improve patient care by providing recommendations about appropriate healthcare in specific circumstances. Development of clinical guidelines is an important component in improving the quality of care. By translating the best available scientific evidence into specific recommendations, guidelines can serve as a useful tool to achieve effective and efficient patient care. In 2009, the first European Society of Cardiology guidelines on perioperative care were developed. This decisionmaking process integrates clinical markers, early coronary evaluation, functional capacity, and the type of surgery involved.
    Keywords guidelines ; noncardiac surgery ; perioperative care ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2010-07-01T00:00:00Z
    Publisher Medycyna Praktyczna
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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