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  1. Article: Polymyxin-induced neuromuscular weakness: a case report.

    Chin, Amanda X Y / Ng, Kay W P / Chan, Yee Cheun / Goh, Yihui / Rathakrishnan, Rahul

    Frontiers in neurology

    2024  Volume 15, Page(s) 1342419

    Abstract: Polymyxin-induced neuromuscular blockade is a rare but potentially fatal condition, with majority of cases that were reported between 1962 and 1973. We describe a patient who developed hypercapnic respiratory failure after initiation of polymyxin for ... ...

    Abstract Polymyxin-induced neuromuscular blockade is a rare but potentially fatal condition, with majority of cases that were reported between 1962 and 1973. We describe a patient who developed hypercapnic respiratory failure after initiation of polymyxin for multi-drug resistant
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2024.1342419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bridging the Gap: Tailoring an Approach to Treatment in Febrile Infection-Related Epilepsy Syndrome.

    Goh, Yihui / Tay, Sen Hee / Yeo, Leonard Leong Litt / Rathakrishnan, Rahul

    Neurology

    2023  Volume 100, Issue 24, Page(s) 1151–1155

    Abstract: Cytokine profiling before immunotherapy is increasingly prevalent in febrile infection-related epilepsy syndrome (FIRES). In this case, an 18-year-old man presented with first-onset seizure after a nonspecific febrile illness. He developed super- ... ...

    Abstract Cytokine profiling before immunotherapy is increasingly prevalent in febrile infection-related epilepsy syndrome (FIRES). In this case, an 18-year-old man presented with first-onset seizure after a nonspecific febrile illness. He developed super-refractory status epilepticus requiring multiple antiseizure medications and general anesthetic infusions. He was treated with pulsed methylprednisolone and plasma exchange and started on ketogenic diet. Contrast-enhanced MRI brain revealed postictal changes. EEG findings showed multifocal ictal runs and generalized periodic epileptiform discharges. CSF analysis, autoantibody testing, and malignancy screening were unremarkable. Genetic testing revealed variants of uncertain significance in the
    MeSH term(s) Male ; Humans ; Adolescent ; Interleukin-6 ; Seizures/complications ; Status Epilepticus/diagnosis ; Cytokines ; Epileptic Syndromes/diagnosis ; Adaptor Proteins, Signal Transducing
    Chemical Substances Interleukin-6 ; Cytokines ; CNKSR2 protein, human ; Adaptor Proteins, Signal Transducing
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Three-Dimensional Morphological Analysis Revealed the Cell Patterning Bases for the Sexual Dimorphism Development in the Liverwort Marchantia polymorpha.

    Cui, Yihui / Hisanaga, Tetsuya / Kajiwara, Tomoaki / Yamaoka, Shohei / Kohchi, Takayuki / Goh, Tatsuaki / Nakajima, Keiji

    Plant & cell physiology

    2023  Volume 64, Issue 8, Page(s) 866–879

    Abstract: In land plants, sexual dimorphism can develop in both diploid sporophytes and haploid gametophytes. While developmental processes of sexual dimorphism have been extensively studied in the sporophytic reproductive organs of model flowering plants such as ... ...

    Abstract In land plants, sexual dimorphism can develop in both diploid sporophytes and haploid gametophytes. While developmental processes of sexual dimorphism have been extensively studied in the sporophytic reproductive organs of model flowering plants such as stamens and carpels of Arabidopsis thaliana, those occurring in gametophyte generation are less well characterized due to the lack of amenable model systems. In this study, we performed three-dimensional morphological analyses of gametophytic sexual branch differentiation in the liverwort Marchantia polymorpha, using high-depth confocal imaging and a computational cell segmentation technique. Our analysis revealed that the specification of germline precursors initiates in a very early stage of sexual branch development, where incipient branch primordia are barely recognizable in the apical notch region. Moreover, spatial distribution patterns of germline precursors differ between males and females from the initial stage of primordium development in a manner dependent on the master sexual differentiation regulator MpFGMYB. At later stages, distribution patterns of germline precursors predict the sex-specific gametangia arrangement and receptacle morphologies seen in mature sexual branches. Taken together, our data suggest a tightly coupled progression of germline segregation and sexual dimorphism development in M. polymorpha.
    MeSH term(s) Marchantia/genetics ; Sex Characteristics ; Germ Cells, Plant ; Arabidopsis
    Language English
    Publishing date 2023-05-25
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 208907-5
    ISSN 1471-9053 ; 0032-0781
    ISSN (online) 1471-9053
    ISSN 0032-0781
    DOI 10.1093/pcp/pcad048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Aseptic meningitis after BNT-162b2 COVID-19 vaccination.

    Chan, Amanda Cy / Tan, Benjamin Yq / Goh, Yihui / Tan, Shaun Sy / Tambyah, Paul A

    Brain, behavior, & immunity - health

    2021  Volume 19, Page(s) 100406

    Abstract: The COVID-19 pandemic has had an unprecedented impact on healthcare systems globally, giving rise to significant morbidity and mortality. Vaccination has been widely regarded as the most important strategy to contain the pandemic. Whilst local side- ... ...

    Abstract The COVID-19 pandemic has had an unprecedented impact on healthcare systems globally, giving rise to significant morbidity and mortality. Vaccination has been widely regarded as the most important strategy to contain the pandemic. Whilst local side-effects of the BNT-162b2 (Pfizer-BioNTech) vaccine are well known, concern has emerged due to sporadic reports of immune-mediated adverse effects (Cines and Bussel, 2021; Rela et al., 2021). As of August 19, 2021, 4.54 million individuals had received COVID-19 vaccines in Singapore (Oxford Martin School UoO, 2021). We report a case series of two patients who developed aseptic meningitis after vaccination.
    Language English
    Publishing date 2021-12-13
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3546
    ISSN (online) 2666-3546
    DOI 10.1016/j.bbih.2021.100406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pearls & Oy-sters: Facial nerve palsy in COVID-19 infection.

    Goh, Yihui / Beh, Darius L L / Makmur, Andrew / Somani, Jyoti / Chan, Amanda C Y

    Neurology

    2020  Volume 95, Issue 8, Page(s) 364–367

    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Comorbidity ; Coronavirus Infections/epidemiology ; Facial Paralysis/epidemiology ; Humans ; Male ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Singapore/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-05-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000009863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Headaches Due to Personal Protective Equipment During COVID-19 Pandemic: A Comment.

    Goh, Yihui / Ong, Jonathan J Y / Bharatendu, Chandra / Tan, Benjamin Y Q / Sharma, Vijay K

    Headache

    2020  Volume 60, Issue 7, Page(s) 1446–1447

    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Headache/epidemiology ; Health Personnel ; Humans ; Pandemics ; Personal Protective Equipment ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 410130-3
    ISSN 1526-4610 ; 0017-8748
    ISSN (online) 1526-4610
    ISSN 0017-8748
    DOI 10.1111/head.13879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: D-penicillamine in Wilson's disease; recognizing the transition from benefit to harm.

    Goh, Yihui / Tan, Benjamin Yong-Qiang / Chong, Nicole Ya-Yuan / Ma, Margaret / Lahiri, Manjari / Makmur, Andrew / Chan, Yee Cheun / Wong, Soon Boon Justin / Vijayan, Joy

    eNeurologicalSci

    2021  Volume 23, Page(s) 100328

    Language English
    Publishing date 2021-02-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2838045-9
    ISSN 2405-6502 ; 2405-6502
    ISSN (online) 2405-6502
    ISSN 2405-6502
    DOI 10.1016/j.ensci.2021.100328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The face mask: How a real protection becomes a psychological symbol during Covid-19?

    Goh, Yihui / Tan, Benjamin Y Q / Bhartendu, Chandra / Ong, Jonathan J Y / Sharma, Vijay K

    Brain, behavior, and immunity

    2020  Volume 88, Page(s) 1–5

    Abstract: The Mask' has become a byword and a precious possession universally. Except for its use by the medical fraternity, answers to the common questions-whether it provides enough protection, which type is optimal for the general public and who really needs ... ...

    Abstract 'The Mask' has become a byword and a precious possession universally. Except for its use by the medical fraternity, answers to the common questions-whether it provides enough protection, which type is optimal for the general public and who really needs to don it, remain poorly understood. For a frontline healthcare worker, wearing mask is a necessity as an important person protection equipment, it is perhaps the most-powerful psychological symbol for the general public. Surprisingly, it even undermines all other recommended practices of infection control and breaking the transmission chain of Covid-19, like hand washing, personal hygiene and social distancing. 'The mask' has evolved with time and yet there is a need to further improve the design for safety, tolerability and comfort. In this review we present the journey of face mask, originating from the first masks aimed at stopping the bad smell to its industrial use to its all-important place in the medical field. Various types of face masks, their filtration efficiency, reusability and current recommendations for their use are presented.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Equipment Reuse ; Guidelines as Topic ; Humans ; Infection Control ; Masks ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Respiratory Protective Devices ; SARS-CoV-2 ; Symbolism ; Textiles
    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2020.05.060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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