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  1. Article ; Online: C···S Tetrel Bond Favored in the Phenyl Isothiocyanate-CO

    Zou, Siyu / Lei, Juncheng / Gao, Tianyue / Xu, Xuefang / Gou, Qian

    The journal of physical chemistry. A

    2023  Volume 127, Issue 47, Page(s) 9959–9965

    Abstract: The rotational spectrum of the phenyl isothiocyanate- ... ...

    Abstract The rotational spectrum of the phenyl isothiocyanate-CO
    Language English
    Publishing date 2023-11-18
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.3c05187
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Engineering Substrate Promiscuity of Nucleoside Phosphorylase Via an Insertions-Deletions Strategy.

    Liu, Gaofei / Wang, Jialing / Chu, Jianlin / Jiang, Tianyue / Qin, Song / Gao, Zhen / He, Bingfang

    JACS Au

    2024  Volume 4, Issue 2, Page(s) 454–464

    Abstract: Nucleoside phosphorylases (NPs) are the key enzymes in the nucleoside metabolism pathway and are widely employed for the synthesis of nucleoside analogs, which are difficult to access via conventional synthetic methods. NPs are generally classified as ... ...

    Abstract Nucleoside phosphorylases (NPs) are the key enzymes in the nucleoside metabolism pathway and are widely employed for the synthesis of nucleoside analogs, which are difficult to access via conventional synthetic methods. NPs are generally classified as purine nucleoside phosphorylase (PNP) and pyrimidine or uridine nucleoside phosphorylase (PyNP/UP), based on their substrate preference. Here, based on the evolutionary information on the NP-I family, we adopted an insertions-deletions (InDels) strategy to engineer the substrate promiscuity of nucleoside phosphorylase
    Language English
    Publishing date 2024-01-13
    Publishing country United States
    Document type Journal Article
    ISSN 2691-3704
    ISSN (online) 2691-3704
    DOI 10.1021/jacsau.3c00581
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  3. Article: For Sustainable Career Development: Framework and Assessment of the Employability of Business English Graduates.

    Tong, Minjun / Gao, Tianyue

    Frontiers in psychology

    2022  Volume 13, Page(s) 847247

    Abstract: Employability is an important indicator of the competency of the employees. Employability model is a useful analytical framework for studying the ever-changing relationship between higher education and the job market. At present, the demand for business ... ...

    Abstract Employability is an important indicator of the competency of the employees. Employability model is a useful analytical framework for studying the ever-changing relationship between higher education and the job market. At present, the demand for business English graduates is increasing, however, there is a skill gap between their educational readiness and the recruitment requirements. In order to solve this problem, this study adopted mixed methods research and carried out the research design according to the exploratory sequence design to construct an employability model for business English graduates. A 46-item scale was developed to measure the employability of business English graduates' employability. After assessment, it was found that the employability of business English graduates was multi-dimensional, with three dimensions-professional knowledge, generic competencies, and career management and 10 sub-dimensions-English language skills, foreign trade competencies, computer and internet application skills, social skills, learning and development, personal traits, thinking ability, work ethics, career identity and planning, and service awareness. This study verified that the employability of business English graduates reached the standard of talent training and met the requirements of employers. There were employability differences in gender, places of origin and educational institutions. From this study, it could be inferred that cultivation of business English majors should be multi-dimensional.
    Language English
    Publishing date 2022-04-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.847247
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  4. Book ; Online: Distributed Optimization in Sensor Network for Scalable Multi-Robot Relative State Estimation

    Wu, Tianyue / Gao, Fei

    2023  

    Abstract: Distance measurements demonstrate distinctive scalability when used for relative state estimation in large-scale multi-robot systems. Despite the attractiveness of distance measurements, multi-robot relative state estimation based on distance ... ...

    Abstract Distance measurements demonstrate distinctive scalability when used for relative state estimation in large-scale multi-robot systems. Despite the attractiveness of distance measurements, multi-robot relative state estimation based on distance measurements raises a tricky optimization problem, especially in the context of large-scale systems. Motivated by this, we aim to develop specialized computational techniques that enable robust and efficient estimation when deploying distance measurements at scale. We first reveal the commonality between the estimation problem and the one that finds realization of a sensor network, from which we draw crucial lesson to inspire the proposed methods. However, solving the latter problem in large-scale (still) requires distributed optimization schemes with scalability natures, efficient computational procedures, and fast convergence rates. Towards this goal, we propose a complementary pair of distributed computational techniques with the classical block coordinate descent (BCD) algorithm as a unified backbone. In the first method, we treat Burer-Monteiro factorization as a rank-restricted heuristic for rank-constrained semidefinite programming (SDP), where a specialized BCD-type algorithm that analytically solve each block update subproblem is employed. Although this method enables robust and (extremely) fast recovery of estimates from initial guesses, it inevitably fails as the initialization becomes disorganized. We therefore propose the second method, derived from a convex formulation named anchored edge-based semidefinite programming} (ESDP), to complement it, at the expense of a certain loss of efficiency. This formulation is structurally decomposable so that BCD can be naturally employed, where each subproblem is convex and (again) solved exactly.

    Comment: Extended technical report (14 pages, 5 figures, 2 tables)
    Keywords Computer Science - Robotics
    Publishing date 2023-03-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Manipulation of IME4 expression, a global regulation strategy for metabolic engineering in

    Zhu, Jianxun / An, Tianyue / Zha, Wenlong / Gao, Ke / Li, Ting / Zi, Jiachen

    Acta pharmaceutica Sinica. B

    2023  Volume 13, Issue 6, Page(s) 2795–2806

    Abstract: Metabolic engineering has been widely used for production of natural medicinal molecules. However, engineering high-yield platforms is hindered in large part by limited knowledge of complex regulatory machinery of metabolic network. ...

    Abstract Metabolic engineering has been widely used for production of natural medicinal molecules. However, engineering high-yield platforms is hindered in large part by limited knowledge of complex regulatory machinery of metabolic network.
    Language English
    Publishing date 2023-01-10
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2211-3835
    ISSN 2211-3835
    DOI 10.1016/j.apsb.2023.01.002
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  6. Article ; Online: Conformational equilibria and interaction preference in the complex of isoprene-maleic anhydride.

    Gao, Tianyue / Lei, Juncheng / Zou, Siyu / Wang, Chenxu / Xu, Xuefang / Gou, Qian

    Physical chemistry chemical physics : PCCP

    2023  Volume 25, Issue 40, Page(s) 27798–27804

    Abstract: The rotational spectrum of the isoprene-maleic anhydride complex has been investigated by pulsed jet Fourier transform microwave spectroscopy and interpreted with complementary quantum chemical calculations. Theoretical predictions have yielded four ... ...

    Abstract The rotational spectrum of the isoprene-maleic anhydride complex has been investigated by pulsed jet Fourier transform microwave spectroscopy and interpreted with complementary quantum chemical calculations. Theoretical predictions have yielded four plausible isomers, all residing within an energy window of 12 kJ mol
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp03712f
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  7. Article ; Online: The Dunning-Kruger effect: subjective health perceptions on smoking behavior among older Chinese adults.

    Jia, Zhike / Li, Shubin / Luo, Zhihua / Tong, Minjun / Gao, Tianyue

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 1703

    Abstract: Background: The intrinsic damage and external hazards of smoking are major risk factors for poorer health and are recognized as a global health issue of concern in geriatric health. This study aims to assess the Dunning-Kruger effect through the ... ...

    Abstract Background: The intrinsic damage and external hazards of smoking are major risk factors for poorer health and are recognized as a global health issue of concern in geriatric health. This study aims to assess the Dunning-Kruger effect through the influence of subjective health perceptions on smoking behavior in older adults.
    Methods: This study used data from the 2018 Chinese Longitudinal Healthy Longevity Survey (N = 9,683) provided by the Center for Healthy Aging and Development Studies at Peking University. A binary logistic model was used to examine whether the Dunning-Kruger effect affects smoking behavior in older adults, and a linear probability model was used as a commentary baseline model for logistic regression to prevent measurement bias. In addition, a mediating analysis was used to examine the mechanisms through which the Dunning-Kruger effect occurs.
    Results: Older adults often overestimated their current health status and underestimated the health risks of smoking, causing the Dunning-Kruger effect to arise from their inadequate self-perceived health (i.e., older adults are more likely to smoke when they have better self-rated health or when hypertension, cardiopathy, stroke, and diabetes have little or no impact on their daily lives). These observations can be explained by the older adults' subjective health perceptions arising from their ingenuous understanding of their health, which indirectly influences their smoking behavior to some extent.
    Conclusion: Older adults' self-perceived health was associated with smoking behavior. Public health institutions should improve older adults' health perceptions so that they objectively understand their own health status.
    MeSH term(s) Aged ; Humans ; Middle Aged ; Diagnostic Self Evaluation ; East Asian People ; Smoking/epidemiology ; Risk Assessment ; Self Concept
    Language English
    Publishing date 2023-09-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-16582-y
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  8. Article ; Online: Viscosity Analysis of Battery Electrode Slurry

    Alex Cushing / Tianyue Zheng / Kenneth Higa / Gao Liu

    Polymers, Vol 13, Iss 4033, p

    2021  Volume 4033

    Abstract: We report the effects of component ratios and mixing time on electrode slurry viscosity. Three component quantities were varied: active material (graphite), conductive material (carbon black), and polymer binder (carboxymethyl cellulose, CMC). The ... ...

    Abstract We report the effects of component ratios and mixing time on electrode slurry viscosity. Three component quantities were varied: active material (graphite), conductive material (carbon black), and polymer binder (carboxymethyl cellulose, CMC). The slurries demonstrated shear-thinning behavior, and suspension properties stabilized after a relatively short mixing duration. However, micrographs of the slurries suggested their internal structures did not stabilize after the same mixing time. Increasing the content of polymer binder CMC caused the greatest viscosity increase compared to that of carbon black and graphite.
    Keywords polymer composite ; slurry ; viscosity ; coating ; energy storage ; lithium-ion rechargeable battery ; Organic chemistry ; QD241-441
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Structural design strategies of microneedle-based vaccines for transdermal immunity augmentation.

    Xu, Guo / Mao, Yukuan / Jiang, Tianyue / Gao, Bingbing / He, Bingfang

    Journal of controlled release : official journal of the Controlled Release Society

    2022  Volume 351, Page(s) 907–922

    Abstract: As microneedle-based vaccines possess advantages of high compliance, moderate invasiveness and convenience that are highly relevant to their unique design, they are becoming an indispensable piece of the puzzle in the field of medical applications. By ... ...

    Abstract As microneedle-based vaccines possess advantages of high compliance, moderate invasiveness and convenience that are highly relevant to their unique design, they are becoming an indispensable piece of the puzzle in the field of medical applications. By selecting appropriate materials and methods convenient for precise control over the structure and morphology, MN-based vaccines with strong mechanical properties and variable forms can be fabricated, and specific biomolecules can be used for monitoring or augmenting human immunity. The structural design strategies of MN-based vaccines are highlighted in this review, following a brief discussion of the mechanism of skin immunity and the classification and fabrication approaches of MNs. The biomedical applications of MN-based vaccines, including sampling from interstitial fluid and therapy in infectious diseases and cancers, have also been demonstrated. Finally, the central challenges in this field and opportunities for future developments are also deliberated.
    MeSH term(s) Humans ; Drug Delivery Systems ; Administration, Cutaneous ; Needles ; Vaccines ; Skin
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-10-11
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 632533-6
    ISSN 1873-4995 ; 0168-3659
    ISSN (online) 1873-4995
    ISSN 0168-3659
    DOI 10.1016/j.jconrel.2022.10.008
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  10. Article ; Online: Nanoassemblies Based on a Cationic Perylene Diimide Derivative and Sodium Dodecyl Sulfate: A Simple Fluorescent Platform for Efficient Analysis of Aflatoxin B

    Zhao, Yijian / Liu, Tianyue / Gao, Jinghui / Zhang, Qiaojuan / Liao, Mengyu / Cheng, He / Tian, Jingsheng / Yao, Zhiyi

    Analytical chemistry

    2023  Volume 95, Issue 21, Page(s) 8250–8257

    Abstract: Aflatoxin ... ...

    Abstract Aflatoxin B
    MeSH term(s) Humans ; Food Contamination/analysis ; Fluorescent Dyes/chemistry ; Aflatoxin B1/analysis ; Sodium Dodecyl Sulfate ; Perylene ; Limit of Detection ; Aptamers, Nucleotide/chemistry ; Biosensing Techniques
    Chemical Substances Fluorescent Dyes ; Aflatoxin B1 (9N2N2Y55MH) ; Sodium Dodecyl Sulfate (368GB5141J) ; perylenediimide ; Perylene (5QD5427UN7) ; Aptamers, Nucleotide
    Language English
    Publishing date 2023-05-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c00170
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