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Article ; Online: A cluster of leptospirosis cases associated with crocodile workers in the Northern Territory, Australia, 2022.

Stark, Astrid M / Nohrenberg, Michael / Draper, Anthony DK / McMahon, Kimberley E / Hewitt, Thalia A / Lomas, Kelly / Krause, Vicki L

Communicable diseases intelligence (2018)

2023 Volume 47

Abstract: Leptospirosis is a worldwide zoonotic waterborne disease endemic in tropical and subtropical climates. Outbreaks have been observed in the Northern Territory (NT) of Australia. We briefly described the epidemiology of leptospirosis in the NT between 2012 ...

Abstract	Leptospirosis is a worldwide zoonotic waterborne disease endemic in tropical and subtropical climates. Outbreaks have been observed in the Northern Territory (NT) of Australia. We briefly described the epidemiology of leptospirosis in the NT between 2012 and 2022, and undertook an investigation of a cluster of three leptospirosis cases observed in crocodile workers between January and December 2022 in the Top End of the NT. A descriptive case series was conducted to investigate the cluster; all three cases were male and non-Aboriginal with a median age of 46.5 years; none took chemoprophylaxis; only one of the three cases reported wearing appropriate protective attire; all reported receiving limited to no education about personal protective measures from their associated workplaces. Higher than average rainfall in both February and December 2022 likely contributed to the increased risk of infection in those months. Changing climate patterns are likely to result in more frequent periods of heavy rain, and risk of contracting leptospirosis in the NT may increase, particularly for those who work in wet and muddy conditions. Promoting the use of protective workplace clothing and equipment, the use of waterproof dressings for skin abrasions, regular hand hygiene, and the consideration of chemoprophylaxis in certain circumstances may prevent future cases.
MeSH term(s)	Animals ; Humans ; Male ; Middle Aged ; Female ; Northern Territory/epidemiology ; Alligators and Crocodiles ; Leptospirosis/epidemiology ; Disease Outbreaks ; Occupational Exposure
Language	English
Publishing date	2023-11-16
Publishing country	Australia
Document type	Journal Article
ISSN	2209-6051
ISSN (online)	2209-6051
DOI	10.33321/cdi.2023.47.70
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An outbreak of leptospirosis associated with cattle workers during the wet season, in the Northern Territory of Australia, 2021.

Brown, Damien R / Peiris, Ruwani / Waller, Claire / Stedman, Elizabeth M / Fitzpatrick, Susanne E / Krause, Vicki L / Draper, Anthony Dk

Communicable diseases intelligence (2018)

2022 Volume 46

Abstract: Abstract: An outbreak of leptospirosis occurred in the Top End of the Northern Territory, Australia, during the wet season in early 2021. There were 14 outbreak cases; most were male (12/14; 86%) and non-Indigenous (13/14; 93%) with a median age of 22 ... ...

Abstract	Abstract: An outbreak of leptospirosis occurred in the Top End of the Northern Territory, Australia, during the wet season in early 2021. There were 14 outbreak cases; most were male (12/14; 86%) and non-Indigenous (13/14; 93%) with a median age of 22 years (range 19-52 years). We conducted a descriptive case series to investigate the outbreak. We determined that the outbreak was most likely due to higher than usual rainfall in a workplace with exposure to cattle, heightened by wearing clothing and footwear which offered little protection, with limited use of personal protective equipment (PPE). Increased and ongoing education for cattle industry workers, and promotion of the use of appropriate clothing and PPE, may minimise the risk of future outbreaks. Australia's national surveillance case definition for leptospirosis should be reviewed to incorporate the use of nucleic acid testing in the detection of leptospirosis.
MeSH term(s)	Animals ; Cattle ; Disease Outbreaks ; Female ; Humans ; Leptospira ; Leptospirosis/diagnosis ; Leptospirosis/epidemiology ; Leptospirosis/veterinary ; Male ; Northern Territory/epidemiology ; Seasons
Language	English
Publishing date	2022-04-26
Publishing country	Australia
Document type	Journal Article
ISSN	2209-6051
ISSN (online)	2209-6051
DOI	10.33321/cdi.2022.46.23
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Article ; Online: The first 2 months of COVID-19 contact tracing in the Northern Territory of Australia, March-April 2020.

Draper, Anthony DK / Dempsey, Karen E / Boyd, Rowena H / Childs, Emma M / Black, Hayley M / Francis, Laura A / Markey, Peter G / Krause, Vicki L

Communicable diseases intelligence (2018)

2020 Volume 44

Abstract: The Northern Territory (NT) Centre for Disease Control (CDC) undertook contact tracing of all notified cases of coronavirus disease 2019 (COVID-19) within the Territory. There were 28 cases of COVID-19 notified in the NT between 1 March and 30 April 2020. ...

Abstract	The Northern Territory (NT) Centre for Disease Control (CDC) undertook contact tracing of all notified cases of coronavirus disease 2019 (COVID-19) within the Territory. There were 28 cases of COVID-19 notified in the NT between 1 March and 30 April 2020. In total 527 people were identified as close contacts over the same period; 493 were successfully contacted; 445 were located in the NT and were subsequently quarantined and monitored for disease symptoms daily for 14 days after contact with a confirmed COVID-19 case. Of these 445 close contacts, 4 tested positive for COVID-19 after developing symptoms; 2/46 contacts who were cruise ship passengers (4.3%, 95% CI 0.5-14.8%) and 2/51 household contacts (3.9%, 95% CI 0.5-13.5%). None of the 326 aircraft passengers or 4 healthcare workers who were being monitored in the NT as close contacts became cases.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Contact Tracing ; Coronavirus Infections/epidemiology ; Family Characteristics ; Humans ; Northern Territory/epidemiology ; Pandemics ; Pneumonia, Viral/epidemiology ; Public Health ; Risk Factors ; SARS-CoV-2 ; Time Factors ; Travel
Keywords	covid19
Language	English
Publishing date	2020-07-02
Publishing country	Australia
Document type	Journal Article
ISSN	2209-6051
ISSN (online)	2209-6051
DOI	10.33321/cdi.2020.44.53
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Article ; Online: The first confirmed human case of rabies, Timor-Leste, 2024.

Amaral Mali, Marcelo / Machado, Filipe de Neri / Moniz, Filomeno Pinto / Bosco Alves Dos Santos, Frederico / Laot, Perpetua Ana Mery Estela / Pereira Tilman, Ari Jayanti / Florindo, Tanizio Ebryes / Barros, Cristovao de Alexandria / Barbosa, Adriano / Oliveira Lima, Jose A / Goncalves, Joao Paulo / Borges, Francisco / Hornay, Elisabeth / Moises, Joanico / de Jesus Neto, Osmenia / Varela, Liliana / da Costa, Agapito / Draper, Anthony Dk / Francis, Joshua R /

Monteiro, Merita Antonio A

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2023 Volume 29, Issue 18

Abstract: In March 2024, the first ever human case of rabies, following a dog bite, was detected in Timor-Leste. This paper briefly discusses the circumstances of transmission, clinical presentation, palliative care of the case and public health measures taken. ... ...

Abstract	In March 2024, the first ever human case of rabies, following a dog bite, was detected in Timor-Leste. This paper briefly discusses the circumstances of transmission, clinical presentation, palliative care of the case and public health measures taken. Timor-Leste was previously considered rabies-free. Any person who is bitten or scratched by an animal that could potentially transmit rabies virus (especially dogs, bats, monkeys or cats) in Timor-Leste should be assessed for consideration of provision of rabies post-exposure prophylaxis.
MeSH term(s)	Rabies/diagnosis ; Rabies/veterinary ; Rabies/transmission ; Humans ; Animals ; Dogs ; Bites and Stings/virology ; Rabies virus/isolation & purification ; Post-Exposure Prophylaxis ; Timor-Leste/epidemiology ; Rabies Vaccines/administration & dosage ; Male ; Cats ; Chiroptera/virology ; Female
Chemical Substances	Rabies Vaccines
Language	English
Publishing date	2023-10-18
Publishing country	Sweden
Document type	Journal Article ; Case Reports
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2024.29.18.2400241
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Article: An outbreak of Salmonella Saintpaul gastroenteritis after attending a school camp in the Northern Territory, Australia.

Draper, Anthony Dk / Morton, Claire N / Heath, Joshua Ni / Lim, Justin A / Markey, Peter G

Communicable diseases intelligence quarterly report

2017 Volume 41, Issue 1, Page(s) E10–E15

Abstract: An outbreak of salmonellosis occurred following attendance at a school camp between 5 and 8 August 2014 in a remote area of the Northern Territory, Australia. We conducted a retrospective cohort study via telephone interviews, using a structured ... ...

Abstract	An outbreak of salmonellosis occurred following attendance at a school camp between 5 and 8 August 2014 in a remote area of the Northern Territory, Australia. We conducted a retrospective cohort study via telephone interviews, using a structured questionnaire that recorded symptoms and exposures to foods and activities during the camp. A case was anyone with laboratory confirmed Salmonella Saintpaul infection or a clinically compatible illness after attending the camp. Environmental health officers from the Environmental Health Branch undertook an investigation and collected water and environmental samples. We interviewed 65 (97%) of the 67 people who attended the camp. There were 60 students and 7 adults. Of the 65 people interviewed, 30 became ill (attack rate 46%); all were students; and 4 had laboratory confirmed S. Saintpaul infection. The most commonly reported symptoms were diarrhoea (100% 30/30), abdominal pain (93% 28/30), nausea (93% 28/30) and fever (70% 21/30). Thirteen people sought medical attention but none required hospitalisation. Illness was significantly associated with drinking cordial at lunch on 7 August (RR 3.8, 95% CI 1.3-11, P < 0.01), as well as drinking cordial at lunch on 8 August (RR 2.1, 95% CI 1.1-4.2, P=0.01). Salmonella spp. was not detected in water samples or wallaby faeces collected from the camp ground. The epidemiological investigation suggests the outbreak was caused by environmental contamination of food or drink and could have occurred during ice preparation or storage, preparation of the cordial or from inadequate sanitising of the cooler from which the cordial was served. This outbreak highlights the risks of food or drink contamination with environmental Salmonella. Those preparing food and drink in campground settings should be vigilant with cleaning, handwashing and disinfection to prevent outbreaks of foodborne disease.
MeSH term(s)	Disease Outbreaks ; Female ; Food Contamination ; Food Microbiology ; Foodborne Diseases/epidemiology ; Gastroenteritis/diagnosis ; Gastroenteritis/epidemiology ; Gastroenteritis/microbiology ; Humans ; Male ; Northern Territory/epidemiology ; Salmonella/classification ; Salmonella/isolation & purification ; Salmonella Food Poisoning/diagnosis ; Salmonella Food Poisoning/epidemiology ; Schools ; Seasons
Language	English
Publishing date	2017-03-31
Publishing country	Australia
Document type	Journal Article
ISSN	1447-4514
ISSN	1447-4514
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Article ; Online: The epidemiology of the COVID-19 pandemic in the small, low-resource country of Timor-Leste, January 2020 - June 2022.

Niha, Maria Av / Draper, Anthony Dk / Viegas, Odete da Silva / de Araujo, Rui M / Joao, Josefina C / da Silva, Endang / Barreto, Ismail / Sarmento, Nevio / Oakley, Tessa / Machado, Filipe de Neri / Fancourt, Nicholas Ss / Marr, Ian / Dos Santos Fernandes, Liliana N / Martins, Noemia / Arkell, Paul / Tilman, Ari Jp / Dingle, Benjamin / Freitas, Carlito C / Bhowmick, Partha S /

Sheridan, Sarah / Howden, Benjamin P / Yan, Jennifer / Francis, Joshua R / Martins, Nelson

Communicable diseases intelligence (2018)

2023 Volume 47

Abstract: Abstract: Timor-Leste, a small, mountainous half-island nation which shares a land border with Indonesia and which is 550 km from Australia, has a population of 1.3 million and achieved independence for the second time in 2002. It is one of the poorest ... ...

Abstract	Abstract: Timor-Leste, a small, mountainous half-island nation which shares a land border with Indonesia and which is 550 km from Australia, has a population of 1.3 million and achieved independence for the second time in 2002. It is one of the poorest nations in Asia. In response to the global coronavirus disease 2019 (COVID-19) pandemic, the Timor-Leste Ministry of Health undertook surveillance and contact tracing activities on all notified COVID-19 cases. Between 1 January 2020 and 30 June 2022, there were 22,957 cases of COVID-19 notified which occurred in three waves, the first which was delayed until April 2021 (community transmission of B.1.466.2 variant following major flooding), followed by waves in August 2021 (B.1.617.2 Delta variant transmission) and February 2022 (B.1.1.529 Omicron variant transmission). There were 753 people hospitalised due to COVID-19 and 133 deaths. Of the 133 deaths, 122 (92%) were considered not fully vaccinated (< 2 COVID-19 vaccines) and none had received boosters. Timor-Leste implemented measures to control COVID-19, including: rapid closure of international borders; isolation of cases; quarantining of international arrivals and close contacts; restrictions on internal travel; social and physical distancing; and, finally, a country-wide vaccination program. The health system's capacity was never exceeded.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics ; Timor-Leste/epidemiology ; COVID-19 Vaccines ; Australia/epidemiology ; SARS-CoV-2
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-01-19
Publishing country	Australia
Document type	Journal Article
ISSN	2209-6051
ISSN (online)	2209-6051
DOI	10.33321/cdi.2023.47.1
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Article ; Online: Serological surveillance of healthcare workers to evaluate natural infection- and vaccine-derived immunity to SARS-CoV-2 during an outbreak in Dili, Timor-Leste.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2022 Volume 119, Page(s) 80–86

Abstract: Background Serosurveillance can be used to investigate the extent and distribution of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within a population. Characterisation of humoral immune responses gives insight into whether ... ...

Abstract	Background Serosurveillance can be used to investigate the extent and distribution of immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within a population. Characterisation of humoral immune responses gives insight into whether immunity is infection- or vaccine-derived. Methods A longitudinal study of health care workers (HCWs) in Dili, Timor-Leste, was conducted during vaccine rollout (ChAdOx1) and a concurrent SARS-CoV-2 outbreak. Results A total of 324 HCWs were included at baseline (April-May 2021). Out of those, 32 (9.9%) were seropositive for anti-nucleocapsid protein (anti-N) IgG antibodies, indicating a significant sub-clinical infection among HCWs early in the local outbreak. Follow-up was conducted in 157 (48.5%) participants (July-September 2021), by which time there had been high uptake of vaccination (91.7%), and 86.0% were seropositive for anti-spike protein antibodies. Acquisition of anti-N antibodies was observed in partially vaccinated HCWs (30/76, 39.5%), indicating some post-dose-1 infections. Discussion Serosurveillance of HCWs may provide early warning of SARS-CoV-2 outbreaks and should be considered in non-endemic settings, particularly where there is limited availability/uptake of testing for acute infection. Characterisation of humoral immune responses may be used to assess vaccine impact and coverage. Such studies should be considered in national and international efforts to investigate and mitigate against future emerging pathogens.
MeSH term(s)	Antibodies, Viral ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Disease Outbreaks/prevention & control ; Health Personnel ; Humans ; Longitudinal Studies ; SARS-CoV-2 ; Timor-Leste ; Vaccination ; Vaccines
Chemical Substances	Antibodies, Viral ; COVID-19 Vaccines ; Vaccines
Language	English
Publishing date	2022-03-28
Publishing country	Canada
Document type	Journal Article
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2022.03.043
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Article: The first 2 months of COVID-19 contact tracing in the Northern Territory of Australia, March-April 2020

Draper, Anthony Dk / Dempsey, Karen E / Boyd, Rowena H / Childs, Emma M / Black, Hayley M / Francis, Laura A / Markey, Peter G / Krause, Vicki L

Abstract	The Northern Territory (NT) Centre for Disease Control (CDC) undertook contact tracing of all notified cases of coronavirus disease 2019 (COVID-19) within the Territory. There were 28 cases of COVID-19 notified in the NT between 1 March and 30 April 2020. In total 527 people were identified as close contacts over the same period; 493 were successfully contacted; 445 were located in the NT and were subsequently quarantined and monitored for disease symptoms daily for 14 days after contact with a confirmed COVID-19 case. Of these 445 close contacts, 4 tested positive for COVID-19 after developing symptoms; 2/46 contacts who were cruise ship passengers (4.3%, 95% CI 0.5-14.8%) and 2/51 household contacts (3.9%, 95% CI 0.5-13.5%). None of the 326 aircraft passengers or 4 healthcare workers who were being monitored in the NT as close contacts became cases.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #630611
Database	COVID19

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Article: An outbreak of salmonellosis associated with duck prosciutto at a Northern Territory restaurant.

Draper, Anthony Dk / Morton, Claire N / Heath, Joshua Ni / Lim, Justin A / Schiek, Anninka I / Davis, Stephanie / Krause, Vicki L / Markey, Peter G

Communicable diseases intelligence quarterly report

2017 Volume 41, Issue 1, Page(s) E16–E20

Abstract: In June 2015, an outbreak of salmonellosis occurred among people who had eaten at a restaurant in Darwin, Northern Territory over 2 consecutive nights. We conducted a retrospective cohort study of diners who ate at the restaurant on 19 and 20 June 2015. ... ...

Abstract	In June 2015, an outbreak of salmonellosis occurred among people who had eaten at a restaurant in Darwin, Northern Territory over 2 consecutive nights. We conducted a retrospective cohort study of diners who ate at the restaurant on 19 and 20 June 2015. Diners were telephoned and a questionnaire recorded symptoms and menu items consumed. An outbreak case was defined as anyone with laboratory confirmed Salmonella Typhimurium PT9 (STm9) or a clinically compatible illness after eating at the restaurant. Environmental health officers inspected the premises and collected food samples. We contacted 79/83 of the cohort (response rate 95%); 21 were cases (attack rate 27%), and 9 had laboratory confirmed STm9 infection. The most commonly reported symptoms were diarrhoea (100%), abdominal pain (95%), fever (95%) and nausea (95%). Fifteen people sought medical attention and 7 presented to hospital. The outbreak was most likely caused by consumption of duck prosciutto, which was consumed by all cases (OR 18.6, CI 3.0-∞, P < 0.01) and was prepared on site. Salmonella was not detected in any food samples but a standard plate count of 2 x 10
MeSH term(s)	Animals ; Disease Outbreaks ; Ducks ; Female ; Food Microbiology ; Humans ; Male ; Northern Territory/epidemiology ; Restaurants ; Salmonella Food Poisoning/diagnosis ; Salmonella Food Poisoning/epidemiology ; Salmonella Food Poisoning/microbiology ; Salmonella Infections/diagnosis ; Salmonella Infections/epidemiology ; Salmonella Infections/microbiology
Language	English
Publishing date	2017-03-31
Publishing country	Australia
Document type	Journal Article
ISSN	1447-4514
ISSN	1447-4514
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Article ; Online: Hyperendemic rheumatic heart disease in a remote Australian town identified by echocardiographic screening.

Francis, Joshua R / Fairhurst, Helen / Hardefeldt, Hilary / Brown, Shannon / Ryan, Chelsea / Brown, Kurt / Smith, Greg / Baartz, Roz / Horton, Ari / Whalley, Gillian / Marangou, James / Kaethner, Alex / Draper, Anthony Dk / James, Christian L / Mitchell, Alice G / Yan, Jennifer / Ralph, Anna / Remenyi, Bo

The Medical journal of Australia

2020 Volume 213, Issue 3, Page(s) 118–123

Abstract: Objectives: Using echocardiographic screening, to estimate the prevalence of rheumatic heart disease (RHD) in a remote Northern Territory town.: Design: Prospective, cross-sectional echocardiographic screening study; results compared with data from ... ...

Abstract	Objectives: Using echocardiographic screening, to estimate the prevalence of rheumatic heart disease (RHD) in a remote Northern Territory town. Design: Prospective, cross-sectional echocardiographic screening study; results compared with data from the NT rheumatic heart disease register. Setting, participants: People aged 5-20 years living in Maningrida, West Arnhem Land (population, 2610, including 2366 Indigenous Australians), March 2018 and November 2018. Intervention: Echocardiographic screening for RHD by an expert cardiologist or cardiac sonographer. Main outcome measures: Definite or borderline RHD, based on World Heart Federation criteria; history of acute rheumatic fever (ARF), based on Australian guidelines for diagnosing ARF. Results: The screening participation rate was 72%. The median age of the 613 participants was 11 years (interquartile range, 8-14 years); 298 (49%) were girls or women, and 592 (97%) were Aboriginal Australians. Definite RHD was detected in 32 screened participants (5.2%), including 20 not previously diagnosed with RHD; in five new cases, RHD was classified as severe, and three of the participants involved required cardiac surgery. Borderline RHD was diagnosed in 17 participants (2.8%). According to NT RHD register data at the end of the study period, 88 of 849 people in Maningrida and the surrounding homelands aged 5-20 years (10%) were receiving secondary prophylaxis following diagnoses of definite RHD or definite or probable ARF. Conclusion: Passive case finding for ARF and RHD is inadequate in some remote Australian communities with a very high burden of RHD, placing children and young people with undetected RHD at great risk of poor health outcomes. Active case finding by regular echocardiographic screening is required in such areas.
MeSH term(s)	Adolescent ; Child ; Child, Preschool ; Cross-Sectional Studies ; Echocardiography ; Female ; Humans ; Logistic Models ; Male ; Mass Screening/methods ; Multivariate Analysis ; Northern Territory/epidemiology ; Oceanic Ancestry Group ; Prevalence ; Prospective Studies ; Rheumatic Fever/diagnostic imaging ; Rheumatic Fever/epidemiology ; Rheumatic Fever/ethnology ; Rheumatic Heart Disease/diagnostic imaging ; Rheumatic Heart Disease/epidemiology ; Rheumatic Heart Disease/ethnology ; Young Adult
Language	English
Publishing date	2020-07-06
Publishing country	Australia
Document type	Journal Article
ZDB-ID	186082-3
ISSN	1326-5377 ; 0025-729X
ISSN (online)	1326-5377
ISSN	0025-729X
DOI	10.5694/mja2.50682
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