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  1. Book ; Online: Challenging Academia: A Critical Space for Controversial Social Issues

    Piper, Heather / Piper, Heather / Leander, M.A.

    2021  

    Keywords Humanities ; Social interaction ; Early Childhood Education and Care ; child sexual abuse ; prevention policies ; no touch ; teacher-child relationships ; male childcare workers ; stigma ; discrimination ; fear ; panopticon ; moral panic ; Brazilian academia ; interviewing for faculty positions ; Lattes CV ; meritocracy ; criminalisation ; harm ; law ; criminal justice ; freedom ; risk ; abuse ; liberal ; victim ; vulnerability ; critical thinking ; identity politics ; academic freedom ; free speech ; victimhood ; anti-discriminatory practice ; neoliberalism ; shadow management ; new public management ; ombudsman ; rule of law ; transparency ; higher education ; body journal ; Coronavirus ; corporal identity ; narratives ; pandemic ; parenthood ; clan ; academic taboo ; Sweden ; state ; postcolonialism ; research methods ; disparity ; disaggregating data ; Asian Americans ; disability ; mental health ; model minority myth ; free inquiry ; censorship ; conformity ; moral panics ; witch hunts ; heresy ; gender mainstreaming ; Lehrfreiheit ; university autonomy ; UNESCO
    Size 1 electronic resource (182 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021290607
    ISBN 9783036508276 ; 3036508279
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Ärztliche Tätigkeit im 21. Jahrhundert - Profession oder Dienstleistung?

    Jonitz, Günther / Piper, Hans Michael / Klinke, Sebastian / Kadmon, Martina

    (Springer-Lehrbuch)

    2018  

    Abstract: Studierende der Humanmedizin sowie Lehrende finden hier Materialien für einen aktuellen und hochwertigen Unterricht für die Querschnittsbereiche Geschichte, Theorie, Ethik der Medizin, Gesundheitsökonomie, Gesundheitssystem, öffentliches Gesundheitswesen. ...

    Author's details Sebastian Klinke, Martina Kadmon (Hrsg.) ; mit Geleitworten von Günther Jonitz und Hans Michael Piper
    Series title Springer-Lehrbuch
    Abstract Studierende der Humanmedizin sowie Lehrende finden hier Materialien für einen aktuellen und hochwertigen Unterricht für die Querschnittsbereiche Geschichte, Theorie, Ethik der Medizin, Gesundheitsökonomie, Gesundheitssystem, öffentliches Gesundheitswesen. Berücksichtigt werden sowohl die gültige Approbationsordnung als auch der Nationale Kompetenzorientierte Lernzielkatalog Medizin (NKLM). Mittels der Leitfragen und Lernziele kann das Buch sowohl für die Vorbereitung von Veranstaltungen als auch für die Formulierung von Prüfungsfragen genutzt werden.

    Arztwerdung und Leistungserbringung im ordnungspolitischen Wandel.- Die Definition von Profession und Beruf.- Professionalität.- Unsicherheit als das zentrale Bezugsproblem der ärztlichen Profession.- Die gesetzliche Krankenversicherung und der Arztberuf als ambivalente Beziehung im Wandel?.- Deprofessionalisierung des Ärztestandes revisited.- Das berufliche Selbstverständnis von Ärzten im DRG-Krankenhaus.- Soziologische Anmerkungen zur ärztlichen Tätigkeit im kommerzialisierten Krankenhaus.- Zum Strukturwandel der Medizin am Beispiel der Krebsforschung.- Der Arzt als Dienstleister?.- Sind Standards objektiv und neutral?.- Die Sozialfigur Arzt.- Die Ordnung der medizinischen (Todes-)Diagnostik.- Getrennte Welten? Auswirkungen neuer Technisierung auf das Arzt-Patient-Verhältnis am Beispiel digitaler Operationstechniken.- Die Dominanz des Arztes.- Vom Spiel zum Ernst.- Zur Rolle der Medizin in einer sich wandelnden Arbeitswelt.
    Keywords Arzt ; Beruf ; Dienstleistung ; Geschichte 2000-2100
    Subject Service ; Berufe ; Mediziner ; Ärzte
    Language German
    Size XIX, 365 Seiten, Diagramme
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT019788278
    ISBN 978-3-662-56646-6 ; 3-662-56646-X ; 9783662566473 ; 3662566478
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Safety of Incision Placement with Nipple-sparing Mastectomy and Immediate Prepectoral Breast Reconstruction.

    Holland, Michael / Wallace, Adam / Viner, Jennifer / Sbitany, Hani / Piper, Merisa

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 1, Page(s) e4736

    Abstract: In nipple-sparing mastectomy, adequate perfusion to the nipple-areolar complex (NAC) during reconstruction is paramount to avoiding unwanted outcomes. Previous studies have suggested that periareolar incisions may result in higher rates of NAC ... ...

    Abstract In nipple-sparing mastectomy, adequate perfusion to the nipple-areolar complex (NAC) during reconstruction is paramount to avoiding unwanted outcomes. Previous studies have suggested that periareolar incisions may result in higher rates of NAC complications. However, studies to date have not specifically investigated this in prepectoral reconstruction. The purpose of this study is to evaluate the impact of incision location on NAC complications in patients undergoing prepectoral breast reconstruction.
    Methods: We performed a retrospective review of all patients who underwent immediate two-stage prepectoral breast reconstruction following nipple-sparing mastectomy between 2015 and 2018 at a single institution. We identified two types of incisions utilized: superior periareolar or inframammary fold (IMF). Patient demographics, comorbidities, and surgical details were compared between incision types, as were NAC complications.
    Results: A total of 181 consecutive prepectoral breast reconstructions were included for analysis. A superior periareolar incision was used in 113 reconstructions (62%), and an IMF incision was used in 68 reconstructions (38%). There were 33 (18%) total NAC complications in our series. The periareolar incision group had a higher rate of any NAC complication (25% versus 7.4%;
    Conclusions: In patients undergoing immediate two-stage prepectoral breast reconstruction following nipple-sparing mastectomy, periareolar incisions are associated with an increased risk of NAC complications compared with IMF incisions. For patients who are candidates for either an IMF or periareolar incision, a periareolar incision should be avoided.
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000004736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Immune Resistance Mechanisms and the Road to Personalized Immunotherapy.

    Piper, Miles / Kluger, Harriet / Ruppin, Eytan / Hu-Lieskovan, Siwen

    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

    2023  Volume 43, Page(s) e390290

    Abstract: What does the future of cancer immunotherapy look like and how do we get there? Find out where we've been and where we're headed in A Report on Resistance: The Road to personalized immunotherapy. ...

    Abstract What does the future of cancer immunotherapy look like and how do we get there? Find out where we've been and where we're headed in A Report on Resistance: The Road to personalized immunotherapy.
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2431126-1
    ISSN 1548-8756 ; 1548-8748
    ISSN (online) 1548-8756
    ISSN 1548-8748
    DOI 10.1200/EDBK_390290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Functional connectivity reveals different brain networks underlying the idiopathic foreign accent syndrome.

    Dadario, Nicholas B / Piper, Keaton / Young, Isabella M / Sherman, Jonathan H / Sughrue, Michael E

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 44, Issue 9, Page(s) 3087–3097

    Abstract: Foreign accent syndrome (FAS) is characterized by new onset speech that is perceived as foreign. Available data from acquired cases suggests focal brain damage in language and sensorimotor brain networks, but little remains known about abnormal ... ...

    Abstract Foreign accent syndrome (FAS) is characterized by new onset speech that is perceived as foreign. Available data from acquired cases suggests focal brain damage in language and sensorimotor brain networks, but little remains known about abnormal functional connectivity in idiopathic cases of FAS without structural damage. Here, connectomic analyses were completed on three patients with idiopathic FAS to investigate unique functional connectivity abnormalities underlying accent change for the first time. Machine learning (ML)-based algorithms generated personalized brain connectomes based on a validated parcellation scheme from the Human Connectome Project (HCP). Diffusion tractography was performed on each patient to rule out structural fiber damage to the language system. Resting-state-fMRI was assessed with ML-based software to examine functional connectivity between individual parcellations within language and sensorimotor networks and subcortical structures. Functional connectivity matrices were created and compared against a dataset of 200 healthy subjects to identify abnormally connected parcellations. Three female patients (28-42 years) who presented with accent changes from Australian English to Irish (n = 2) or American English to British English (n = 1) demonstrated fully intact language system structural connectivity. All patients demonstrated functional connectivity anomalies within language and sensorimotor networks in numerous left frontal regions and between subcortical structures in one patient. Few commonalities in functional connectivity anomalies were identified between all three patients, specifically 3 internal-network parcellation pairs. No common inter-network functional connectivity anomalies were identified between all patients. The current study demonstrates specific language, and sensorimotor functional connectivity abnormalities can exist and be quantitatively shown in the absence of structural damage for future study.
    MeSH term(s) Humans ; Female ; Australia ; Brain/diagnostic imaging ; Language ; Connectome ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-03-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-06762-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Efficacy and safety of vibrating capsule in treatment of chronic idiopathic constipation: a systematic review and meta-analysis of randomized controlled trials.

    Haghbin, Hossein / Zakirkhodjaev, Nurruddinkhodja / Gangwani, Manesh Kumar / Beran, Azizullah / Lee-Smith, Wade / Piper, Michael H / Aziz, Muhammad

    Translational gastroenterology and hepatology

    2024  Volume 9, Page(s) 8

    Abstract: Background: Multiple pharmacological interventions and modalities are available for managing chronic idiopathic constipation (CIC), with variable efficacy. Vibrating capsule (VC) is a device that has shown variable results in alleviating constipation by ...

    Abstract Background: Multiple pharmacological interventions and modalities are available for managing chronic idiopathic constipation (CIC), with variable efficacy. Vibrating capsule (VC) is a device that has shown variable results in alleviating constipation by tactile stimulation of the colonic wall and inducing peristalsis. This meta-analysis is to investigate the efficacy and safety of this modality.
    Methods: Comprehensive literature search was performed through June 14th, 2023, on databases including Embase, PubMed/MEDLINE, Cochrane Central, Web of Science, Global Index Medicus, and Google Scholar. Core concepts of VC, constipation, and bowel movement were searched. The DerSimonian-Laird method and random effects model were utilized. We calculated odds ratio (OR) and mean difference (MD) for proportional and continuous variables, respectively, with 95% confidence interval (CI) and a P value of <0.05 considered statistically significant.
    Results: The search strategy yielded 117 articles. Four studies with 705 total patients were finalized comparing VC to placebo/sham treatment. The pooled complete spontaneous bowel movement (CSBM), defined as bowel movement without use of laxatives within the last 48 hours with sense of complete evacuation did not achieve statistical improvement with VC (MD =0.153; 95% CI: -0.218 to 0.523; P=0.422). However, spontaneous bowel movement (SBM), defined as bowel movement without use of laxatives within the last 48 hours, showed statistical improvement with VC (MD =0.159; 95% CI: 0.095 to 0.223; P<0.001). VC didn't show an increase in pooled adverse events (OR =1.431; 95% CI: 0.702 to 2.916; P=0.324).
    Conclusions: The systematic review and meta-analysis suggest that VC is safe and efficacious in some outcomes, however, larger randomized controlled trials (RCTs) and real-world data are needed to establish this.
    Language English
    Publishing date 2024-01-16
    Publishing country China
    Document type Journal Article
    ISSN 2415-1289
    ISSN (online) 2415-1289
    DOI 10.21037/tgh-23-64
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Wetting-induced soil CO

    Andrews, Holly M / Krichels, Alexander H / Homyak, Peter M / Piper, Stephanie / Aronson, Emma L / Botthoff, Jon / Greene, Aral C / Jenerette, G Darrel

    Global change biology

    2023  Volume 29, Issue 11, Page(s) 3205–3220

    Abstract: Warming-induced changes in precipitation regimes, coupled with anthropogenically enhanced nitrogen (N) deposition, are likely to increase the prevalence, duration, and magnitude of soil respiration pulses following wetting via interactions among ... ...

    Abstract Warming-induced changes in precipitation regimes, coupled with anthropogenically enhanced nitrogen (N) deposition, are likely to increase the prevalence, duration, and magnitude of soil respiration pulses following wetting via interactions among temperature and carbon (C) and N availability. Quantifying the importance of these interactive controls on soil respiration is a key challenge as pulses can be large terrestrial sources of atmospheric carbon dioxide (CO
    MeSH term(s) Soil ; Temperature ; Carbon Dioxide ; Nitrogen ; Colorado ; Water
    Chemical Substances Soil ; Carbon Dioxide (142M471B3J) ; Nitrogen (N762921K75) ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1281439-8
    ISSN 1365-2486 ; 1354-1013
    ISSN (online) 1365-2486
    ISSN 1354-1013
    DOI 10.1111/gcb.16669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Rapid, Simple, and Inexpensive Spatial Patterning of Wettability in Microfluidic Devices for Double Emulsion Generation.

    Liu, Hangrui / Piper, James A / Li, Ming

    Analytical chemistry

    2021  Volume 93, Issue 31, Page(s) 10955–10965

    Abstract: Water-in-oil-in-water (w/o/w) double emulsion (DE) encapsulation has been widely used as a promising platform technology for various applications in the fields of food, cosmetics, pharmacy, chemical engineering, materials science, and synthetic biology. ... ...

    Abstract Water-in-oil-in-water (w/o/w) double emulsion (DE) encapsulation has been widely used as a promising platform technology for various applications in the fields of food, cosmetics, pharmacy, chemical engineering, materials science, and synthetic biology. Unfortunately, DEs formed by conventional emulsion generation approaches in most cases are highly polydisperse, making them less desirable for quantitative assays, controlled biomaterial synthesis, and entrapped ingredient release. Microfluidic devices can generate monodisperse DEs with controllable size, morphology, and production rate, but these generally require multistep fabrication processes and use of different solvents or bulky external instrumentation to pattern channel wettability. To overcome these limitations, we propose a rapid, simple, and inexpensive method to spatially pattern wettability in microfluidic devices for the continuous generation of monodisperse DEs. This is achieved by applying corona-plasma treatment to a select zone of the microchannel surface aided by a custom-designed corona resistance microchannel to strictly confine the plasma-treatment zone in a single polydimethylsiloxane (PDMS) microfluidic device. The properties of PDMS channel surfaces and key microchannel regions for DE generation are characterized under different levels of treatment. The size, shell thickness, and number of inner cores of generated DEs are shown to be highly controllable by tuning the phase flow rate ratios. Using DEs as templates, we successfully achieve a one-step generation and collection of gelatin microgels. Additionally, we demonstrate the biological capability of generated DEs by flow cytometric screening of the encapsulation and growth of yeast cells within DEs. We expect that the proposed approach will be widely used to create microfluidic devices with more complex wettability patterns.
    MeSH term(s) Emulsions ; Flow Cytometry ; Lab-On-A-Chip Devices ; Water ; Wettability
    Chemical Substances Emulsions ; Water (059QF0KO0R)
    Language English
    Publishing date 2021-07-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.1c01861
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Long-Term Outcomes in Prepectoral versus Subpectoral Two-Stage Implant-Based Breast Reconstruction after Nipple-Sparing Mastectomy.

    Alcon, Andre / Rosser, Micaela / Gedallovich, Jodi / Foster, Robert D / Sbitany, Hani / Piper, Merisa L

    Plastic and reconstructive surgery

    2023  Volume 152, Issue 2, Page(s) 273–280

    Abstract: Background: Implant-based breast reconstruction remains the most often used method following mastectomy, but data are lacking regarding differences in complications and long-term patient-reported outcomes for two-stage subpectoral versus prepectoral ... ...

    Abstract Background: Implant-based breast reconstruction remains the most often used method following mastectomy, but data are lacking regarding differences in complications and long-term patient-reported outcomes for two-stage subpectoral versus prepectoral reconstruction. This study sought to better understand the risks and impact of these reconstructive approaches on overall satisfaction.
    Methods: Patients who underwent unilateral or bilateral nipple-sparing mastectomy and two-stage implant-based reconstruction from 2014 to 2019 were identified from the electronic medical records and contacted via email to complete the BREAST-Q survey. Overall satisfaction was measured by the question, "How happy are you with the outcome of your breast reconstruction?" using a six-point Likert scale. Patients were grouped into subpectoral or prepectoral cohorts. Complications were evaluated retrospectively. Only patients who were at least 6 months from their final reconstruction were included in the analysis.
    Results: Of the 582 patients contacted, 206 (35%) responded. The subpectoral ( n = 114) and prepectoral ( n = 38) groups did not differ significantly by demographic or treatment characteristics. BREAST-Q scores were also comparable. Complication rates were similar, but prepectoral patients had a significantly higher rate of capsular contracture (16% versus 4%, P < 0.05). Bivariate ordered logistic regression identified prepectoral implant placement, having any postoperative complication, and capsular contracture as predictors of less overall happiness.
    Conclusions: The authors' study suggests that prepectoral patients may have slightly higher complication rates but are as satisfied as subpectoral patients after at least a year of follow-up. Further studies should investigate risk factors for capsular contracture, how the risk changes over time, and how the risk affects patient satisfaction.
    MeSH term(s) Humans ; Female ; Mastectomy/adverse effects ; Mastectomy/methods ; Breast Implantation/adverse effects ; Breast Implantation/methods ; Breast Implants/adverse effects ; Retrospective Studies ; Nipples/surgery ; Breast Neoplasms/surgery ; Breast Neoplasms/etiology ; Mammaplasty/adverse effects ; Mammaplasty/methods ; Contracture/etiology
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000010251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Does Head Positioning After Percutaneous Glycerol Rhizotomy for Trigeminal Neuralgia Matter?

    Piper, Keaton / Smith, Teagen / Saez-Alegre, Miguel / Jean, Walter / Bezchlibnyk, Yarema / Van Loveren, Harry

    World neurosurgery

    2023  Volume 181, Page(s) e447–e452

    Abstract: Background: Percutaneous glycerol rhizotomy (PGR) is a minimally invasive procedure for patients with trigeminal neuralgia who are not candidates for microvascular decompression. PGR has widely varying success rates. It has been postulated that ... ...

    Abstract Background: Percutaneous glycerol rhizotomy (PGR) is a minimally invasive procedure for patients with trigeminal neuralgia who are not candidates for microvascular decompression. PGR has widely varying success rates. It has been postulated that differences in post-injection head positioning might account for the various success rates.
    Methods: By comparing glycerol dispersion after injection at various head positions, we provide the first evidence supporting post-injection head flexion positioning. Furthermore, we study the clival-Meckel cave (CMC) angle as a predictor of beneficial glycerol flow, measured on computed tomography images. Twenty-two dissected cadaveric specimens were injected with dyed glycerol through the Hartel approach. The glycerol dispersion was measured at prespecified intervals for 1 hour. The Mann-Whitney U and χ
    Results: We found that 30° of anterior head flexion provided optimal trigeminal nerve glycerol submersion (81.82%) in comparison to neutral (27.27%) and 15° (68.18%), P < 0.001. There was minimal unfavorable dispersion beyond 30 minutes at all angles. More obtuse CMC angles were associated with higher rates of unfavorable BC dispersion (U = 6.0; P = 0.001). For specimens with CMC angles >75°, unfavorable BC dispersion was prevented by head flexion (U = 4.5; P = 0.021). We show that 30° of lateral head tilt achieves V1 submersion in all specimens by 30 minutes [X
    Conclusions: We found that 30° anterior head flexion for >30 minutes provides ideal conditions for PGR to avoid BC dispersion and ensure V1-V3 branches achieve glycerol submersion. For patients with V1 symptoms, contralateral head flexion might help optimize treatment effects.
    MeSH term(s) Humans ; Trigeminal Neuralgia/surgery ; Rhizotomy/methods ; Glycerol ; Treatment Outcome ; Trigeminal Nerve/surgery
    Chemical Substances Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.10.078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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