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Article: Site-Specific Volumetric Skeletal Changes in Women with a Distal Forearm Fracture.

Wihlborg, Axel / Bergström, Karin / Bergström, Ingrid / Gerdhem, Paul

Journal of osteoporosis

2021 Volume 2021, Page(s) 1578543

Abstract: Purpose: To assess site-specific volumetric bone and muscle changes, as well as demographic and biochemical changes, in postmenopausal women with a low-energy distal forearm fracture.: Methods: In a cross-sectional case-control study, postmenopausal ... ...

Abstract	Purpose: To assess site-specific volumetric bone and muscle changes, as well as demographic and biochemical changes, in postmenopausal women with a low-energy distal forearm fracture. Methods: In a cross-sectional case-control study, postmenopausal women with a distal forearm fracture were compared with age- and gender-matched controls. In total, 203 postmenopausal women (104 cases and 99 controls), with a mean age of 65 years, were included. Measurements included peripheral quantitative computed tomography (pQCT) and dual-energy X-ray absorptiometry (DXA) as well as blood sampling and questionnaires. Results: Forearm trabecular volumetric BMD and total BMD assessed with pQCT were significantly lower in fracture cases compared to controls ( Conclusion: A distal forearm fracture was associated with site-specific and central bone changes. Postmenopausal women with fracture had a larger bone area in combination with a thinner cortex and lower site-specific total BMD. In addition, women with fracture had a higher activity level, an increased occurrence of previous fall accidents, and a high prevalence of vertebral fractures. Forearm muscle composition, PTH, and 25OHD were not associated with forearm fracture. Fracture preventive measures following a low-energy distal forearm fracture seem beneficial.
Language	English
Publishing date	2021-09-30
Publishing country	United States
Document type	Journal Article
ISSN	2090-8059
ISSN	2090-8059
DOI	10.1155/2021/1578543
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Article ; Online: Parathyroid Hormone Disturbances in Postmenopausal Women with Distal Forearm Fracture.

Wihlborg, Axel / Bergström, Karin / Gerdhem, Paul / Bergström, Ingrid

World journal of surgery

2021 Volume 46, Issue 1, Page(s) 128–135

Abstract: Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder with a wide range of adverse effects, such as osteoporosis. Many women are not diagnosed due to asymptomatic disease or vague symptoms but are still at risk of severe adverse ... ...

Abstract	Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder with a wide range of adverse effects, such as osteoporosis. Many women are not diagnosed due to asymptomatic disease or vague symptoms but are still at risk of severe adverse effects. Early identification of patients with PHPT is therefore of importance. The aim of this study was to determine PHPT prevalence among postmenopausal women with a distal forearm fracture. Methods: Recruitment was conducted in conjunction with the occurrence of a distal forearm fracture at Karolinska University Hospital. In total, 161 postmenopausal women were included in a cross-sectional study with repeated evaluations. Analyzes of serum calcium, ionized calcium, phosphate, parathyroid hormone (PTH), and vitamin D were performed. Diagnosis of PHPT was based on clinical evaluations and biochemical definitions of serum calcium and PTH in coherence with previous population prevalence reports. Results: Mean age was 64.7 (9.5) years, serum calcium 2.33 (0.10) mmol/L, ionized calcium 1.25 (0.05) mmol/L and PTH 54 (26) ng/L. PTH was elevated in 32 (20%) women. In total, 11 (6.8%) women were diagnosed with PHPT; 6 with classical PHPT and 5 with mild PHPT. The prevalence of PHPT was significantly increased compared to the population prevalence of 3.4% (p = 0.022). Conclusion: Screening postmenopausal women in conjunction with low-energy distal forearm fracture revealed a large number of women with parathyroid disturbance. Evaluation of parathyroid hormone and calcium status in this group of patients seems beneficial.
MeSH term(s)	Calcium ; Cross-Sectional Studies ; Female ; Forearm ; Humans ; Hyperparathyroidism, Primary ; Middle Aged ; Parathyroid Hormone ; Postmenopause
Chemical Substances	Parathyroid Hormone ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2021-10-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	224043-9
ISSN	1432-2323 ; 0364-2313
ISSN (online)	1432-2323
ISSN	0364-2313
DOI	10.1007/s00268-021-06331-w
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Article: Incidence and Risk Factors for Surgical Site Infection in Ankle Fractures: An Observational Study of 480 Patients in Sweden.

Bergström, Johanna / Möller Rydberg, Emilia / Wennergren, David / Svensson Malchau, Karin

Journal of clinical medicine

2023 Volume 12, Issue 20

Abstract: Introduction: Surgical site infection (SSI) is a frequently reported complication after ankle fracture surgery. To our knowledge, no study has been conducted on its incidence in Sweden. The present study aimed to determine the incidence of, risk factors ...

Abstract	Introduction: Surgical site infection (SSI) is a frequently reported complication after ankle fracture surgery. To our knowledge, no study has been conducted on its incidence in Sweden. The present study aimed to determine the incidence of, risk factors for, and most common causative pathogen of SSI. Methods: Patients who underwent primary surgery for an ankle fracture between 1 September 2017 and 31 August 2019 at the Sahlgrenska University Hospital were identified. Data on potential SSI risk factors and clinical outcome (infected/non-infected) were retrieved from medical records. Cox regression analysis and descriptive statistics were used. Results: Of the 480 reviewed patients, 49 developed SSI (10.2%), of which 35 (7.3%) were superficial and 14 (2.9%) were deep. Open fractures ( Conclusions: An incidence of 10.2% was established, which is comparable to international findings. Infection monitoring is an important part of tackling the global challenge of antibiotic resistance. Future prospective studies to further establish risk factors are warranted to decrease the incidence of SSI.
Language	English
Publishing date	2023-10-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12206464
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Article ; Online: Site-Specific Volumetric Skeletal Changes in Women with a Distal Forearm Fracture

Axel Wihlborg / Karin Bergström / Ingrid Bergström / Paul Gerdhem

Journal of Osteoporosis, Vol

2021 Volume 2021

Abstract: Purpose. To assess site-specific volumetric bone and muscle changes, as well as demographic and biochemical changes, in postmenopausal women with a low-energy distal forearm fracture. Methods. In a cross-sectional case-control study, postmenopausal women ...

Abstract	Purpose. To assess site-specific volumetric bone and muscle changes, as well as demographic and biochemical changes, in postmenopausal women with a low-energy distal forearm fracture. Methods. In a cross-sectional case-control study, postmenopausal women with a distal forearm fracture were compared with age- and gender-matched controls. In total, 203 postmenopausal women (104 cases and 99 controls), with a mean age of 65 years, were included. Measurements included peripheral quantitative computed tomography (pQCT) and dual-energy X-ray absorptiometry (DXA) as well as blood sampling and questionnaires. Results. Forearm trabecular volumetric BMD and total BMD assessed with pQCT were significantly lower in fracture cases compared to controls (p<0.001). Significantly higher cross-sectional area, lower cortical BMD, and lower cortical thickness were seen in women with fracture (p<0.033, p<0.001, and p<0.001, respectively). Postmenopausal women with fracture had significantly lower hip and spine areal BMD assessed with DXA (p<0.001). Activity level was higher and a history of falling was more frequent in women with fracture (p<0.019 and p<0.001, respectively). Vertebral fracture was observed in 24 women (22%) with a distal forearm fracture. Muscle area, muscle density, PTH, and 25OHD did not differ between fracture cases and controls. Conclusion. A distal forearm fracture was associated with site-specific and central bone changes. Postmenopausal women with fracture had a larger bone area in combination with a thinner cortex and lower site-specific total BMD. In addition, women with fracture had a higher activity level, an increased occurrence of previous fall accidents, and a high prevalence of vertebral fractures. Forearm muscle composition, PTH, and 25OHD were not associated with forearm fracture. Fracture preventive measures following a low-energy distal forearm fracture seem beneficial.
Keywords	Medicine ; R
Subject code	610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
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Article ; Online: Impact of the COVID-19 pandemic on lymphoma incidence and short-term survival - a Swedish Lymphoma Register Study.

Ekberg, Sara / Molin, Daniel / Pahnke, Simon / Bergström, Fanny / Brånvall, Elsa / Smedby, Karin E / Wästerlid, Tove

Acta oncologica (Stockholm, Sweden)

2024 Volume 63, Page(s) 164–168

Abstract: Background & purpose: The COVID-19 pandemic posed a large challenge for healthcare systems across the world. Comprehensive data on the impact of the COVID-19 pandemic on incidence and mortality in lymphoma are lacking.: Patients/methods: Using data ... ...

Abstract	Background & purpose: The COVID-19 pandemic posed a large challenge for healthcare systems across the world. Comprehensive data on the impact of the COVID-19 pandemic on incidence and mortality in lymphoma are lacking. Patients/methods: Using data from the Swedish lymphoma register, we compare incidence and 1-year survival of lymphoma patients in Sweden before (2017-2019) and during the pandemic (2020 and 2021). Results: Fewer patients were diagnosed with lymphomas during March-June 2020, but the annual incidence rates for 2020 and 2021 were similar to those of 2017-2019. A larger proportion of patients presented with stage IV disease during 2021. There were no differences in other base-line characteristics nor application of active treatment in pre-pandemic and pandemic years. One-year overall survival was not inferior among lymphoma patients during the pandemic years compared to pre-pandemic years i.e., 2017-2019. Interpretation: The COVID-19 pandemic had limited impact on the incidence and mortality of lymphoma in Sweden.
MeSH term(s)	Humans ; Incidence ; Sweden/epidemiology ; Pandemics ; COVID-19/epidemiology ; Lymphoma/epidemiology ; Lymphoma/pathology
Language	English
Publishing date	2024-04-09
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	896449-x
ISSN	1651-226X ; 0349-652X ; 0284-186X ; 1100-1704
ISSN (online)	1651-226X
ISSN	0349-652X ; 0284-186X ; 1100-1704
DOI	10.2340/1651-226X.2024.35238
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Zs.A 6348: Show issues

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Article ; Online: Dysphagia terminology for texture modified fluid and food: a national survey of speech-language pathologists' practice.

Yli-Hukka, Julia / Lignell, Joanna / Eriksson, Karin / Bergström, Liza

Logopedics, phoniatrics, vocology

2022 , Page(s) 1–11

Abstract: Purpose: To investigate: (a) Swedish Speech-Language Pathologists (SLPs) dysphagia management with TMC, including terminology, inter-professional collaboration, and knowledge of standard TMC guides; and (b) the current TMC terminology/guides used within ...

Abstract	Purpose: To investigate: (a) Swedish Speech-Language Pathologists (SLPs) dysphagia management with TMC, including terminology, inter-professional collaboration, and knowledge of standard TMC guides; and (b) the current TMC terminology/guides used within university hospitals, in Sweden. Method: Part One surveyed SLPs from 19/21 regions. Recruitment occurred via regional SLP/department managers, the national SLP association and email lists. Non-parametric statistics were employed. Part Two explored TMC guides within the seven university hospitals. Result: The initial survey identified 78 Swedish TMC terms. Overlap of both TMC Conclusion: Variable TMC terminology is used in Sweden, impacting optimal dysphagia management. Future research should focus upon implementation of standardised TMC terminology.
Language	English
Publishing date	2022-09-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1340538-x
ISSN	1651-2022 ; 1401-5439
ISSN (online)	1651-2022
ISSN	1401-5439
DOI	10.1080/14015439.2022.2117844
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Zs.A 5910: Show issues

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Article ; Online: Long-Term Cost-Effectiveness through the Dental-Health FRAMM Guideline for Caries Prevention.

Davidson, Thomas / Bergström, Eva-Karin / Husberg, Magnus / Moberg Sköld, Ulla

International journal of environmental research and public health

2022 Volume 19, Issue 4

Abstract: A guideline called FRAMM, which is an acronym in Swedish for the most important parts of this guideline, namely "fluoride", "advice", "arena", "motivation" and "diet", was implemented in 2008 in the Västra Götaland Region in Sweden. This guideline ... ...

Abstract	A guideline called FRAMM, which is an acronym in Swedish for the most important parts of this guideline, namely "fluoride", "advice", "arena", "motivation" and "diet", was implemented in 2008 in the Västra Götaland Region in Sweden. This guideline included fluoride varnish applications performed at school twice a year at six-monthly intervals for all 12- to 15-year-olds, together with lessons on oral health. The aim of this analysis was to estimate the long-term cost-effectiveness, using prognostic calculations, of the FRAMM Guideline for 12- to 15-year-olds, compared with routine care, until the participants were 23 years old. A cost-effectiveness analysis was performed from a health care perspective, based on four years of verified data and seven years of prognosis. Data from FRAMM were combined with cost data from price lists in Sweden. The cost-effectiveness was analyzed by relating the difference in costs to the difference in the number of approximal surfaces with fillings and/or dentin lesions (DFSa). The analysis shows that FRAMM was considered dominant compared to the controls in all alternative scenarios, hence costs were prognosed to be lowered and outcomes were prognosed to be improved. A dental health program like the FRAMM Guideline with fluoride varnish during the caries risk period from 12 to 15 years is predicted to be cost-effective in the longer perspective. To further study the actual long-term caries increment after a preventive dental health program would be of great interest to verify these results.
MeSH term(s)	Adult ; Cariostatic Agents ; Cost-Benefit Analysis ; Dental Caries/prevention & control ; Dental Caries Susceptibility ; Fluorides ; Fluorides, Topical/therapeutic use ; Humans ; Young Adult
Chemical Substances	Cariostatic Agents ; Fluorides, Topical ; Fluorides (Q80VPU408O)
Language	English
Publishing date	2022-02-10
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19041954
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Article ; Online: Corrigendum:"Long-distance transport of per- and polyfluoroalkyl substances (PFAS) in a Swedish drinking water aquifer" [Environ. Pollut. 311(2022) 119981].

Sörengård, Mattias / Bergström, Sofia / McCleaf, Philip / Wiberg, Karin / Ahrens, Lutz

Environmental pollution (Barking, Essex : 1987)

2022 Volume 316, Issue Pt 2, Page(s) 120588

Language	English
Publishing date	2022-11-14
Publishing country	England
Document type	Published Erratum
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2022.120588
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Article ; Online: Long-Term Cost-Effectiveness through the Dental-Health FRAMM Guideline for Caries Prevention

Thomas Davidson / Eva-Karin Bergström / Magnus Husberg / Ulla Moberg Sköld

International Journal of Environmental Research and Public Health, Vol 19, Iss 1954, p

2022 Volume 1954

Abstract: A guideline called FRAMM, which is an acronym in Swedish for the most important parts of this guideline, namely “fluoride”, “advice”, “arena”, “motivation” and “diet”, was implemented in 2008 in the Västra Götaland Region in Sweden. This guideline ... ...

Abstract	A guideline called FRAMM, which is an acronym in Swedish for the most important parts of this guideline, namely “fluoride”, “advice”, “arena”, “motivation” and “diet”, was implemented in 2008 in the Västra Götaland Region in Sweden. This guideline included fluoride varnish applications performed at school twice a year at six-monthly intervals for all 12- to 15-year-olds, together with lessons on oral health. The aim of this analysis was to estimate the long-term cost-effectiveness, using prognostic calculations, of the FRAMM Guideline for 12- to 15-year-olds, compared with routine care, until the participants were 23 years old. A cost-effectiveness analysis was performed from a health care perspective, based on four years of verified data and seven years of prognosis. Data from FRAMM were combined with cost data from price lists in Sweden. The cost-effectiveness was analyzed by relating the difference in costs to the difference in the number of approximal surfaces with fillings and/or dentin lesions (DFSa). The analysis shows that FRAMM was considered dominant compared to the controls in all alternative scenarios, hence costs were prognosed to be lowered and outcomes were prognosed to be improved. A dental health program like the FRAMM Guideline with fluoride varnish during the caries risk period from 12 to 15 years is predicted to be cost-effective in the longer perspective. To further study the actual long-term caries increment after a preventive dental health program would be of great interest to verify these results.
Keywords	adolescents ; approximal tooth surfaces ; caries prevalence ; cost-effectiveness ; fluoride varnish ; school-based ; Medicine ; R
Subject code	670
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Long-distance transport of per- and polyfluoroalkyl substances (PFAS) in a Swedish drinking water aquifer.

Sörengård, Mattias / Bergström, Sofia / McCleaf, Philip / Wiberg, Karin / Ahrens, Lutz

Environmental pollution (Barking, Essex : 1987)

2022 Volume 311, Page(s) 119981

Abstract: Use of per- and polyfluoroalkyl substance (PFAS)-containing aqueous film-forming foams (AFFF) at firefighting training sites (FFTS) has been linked to PFAS contamination of drinking water. This study investigated PFAS transport and distribution in an ... ...

Abstract	Use of per- and polyfluoroalkyl substance (PFAS)-containing aqueous film-forming foams (AFFF) at firefighting training sites (FFTS) has been linked to PFAS contamination of drinking water. This study investigated PFAS transport and distribution in an urban groundwater aquifer used for drinking water production that has been affected by PFAS-containing AFFF. Soil, sediment, surface water and drinking water were sampled. In soil (n = 12) at a FFTS with high perfluorooctane sulfonate (PFOS) content (87% of ∑PFAS), the ∑PFAS concentration (n = 26) ranged from below detection limit to 560 ng g
MeSH term(s)	Alkanesulfonic Acids/analysis ; Drinking Water/analysis ; Fluorocarbons/analysis ; Groundwater ; Soil ; Sweden ; Water Pollutants, Chemical/analysis
Chemical Substances	Alkanesulfonic Acids ; Drinking Water ; Fluorocarbons ; Soil ; Water Pollutants, Chemical
Language	English
Publishing date	2022-08-18
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2022.119981
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