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  1. Book: Brain imaging in behavioral neuroscience

    Carter, Cameron S.

    (Current topics in behavioral neurosciences ; 11)

    2012  

    Author's details Cameron S. Carter ... ed
    Series title Current topics in behavioral neurosciences ; 11
    Collection
    Keywords Neuropsychiatrie ; Neuropathologie ; Positronen-Emissions-Tomografie ; Kernspintomografie
    Subject Kernspintomographie ; NMR-Tomographie ; Magnetische Kernresonanztomographie ; MR-Tomographie ; Kernspinresonanztomographie ; MRI ; Magnetic resonance imaging ; IRM ; Magnetresonanztomographie ; Magnetresonanztomografie ; MRT ; NMR-Tomografie ; Nukleare Kernspintomographie ; MR-Bildgebung ; Positronen-Emissions-Tomographie ; PET
    Language English
    Size X, 391 S. : Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Heidelberg u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017283837
    ISBN 978-3-642-28710-7 ; 3-642-28710-7 ; 9783642287114 ; 3642287115
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 2641 order for loan Magazin

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  2. Article ; Online: Further evidence that MRI based measurement of midbrain neuromelanin may serve as a proxy measure of brain dopamine activity in psychiatric disorders.

    Carter, Cameron S

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    2021  Volume 46, Issue 7, Page(s) 1231–1232

    MeSH term(s) Depression ; Dopamine ; Humans ; Magnetic Resonance Imaging ; Melanins ; Mental Disorders ; Mesencephalon/diagnostic imaging
    Chemical Substances Melanins ; neuromelanin ; Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2021-02-01
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 639471-1
    ISSN 1740-634X ; 0893-133X
    ISSN (online) 1740-634X
    ISSN 0893-133X
    DOI 10.1038/s41386-020-00944-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article ; Online: Are We There Yet? Predicting Conversion to Psychosis Using Machine Learning.

    Smucny, Jason / Davidson, Ian / Carter, Cameron S

    The American journal of psychiatry

    2023  Volume 180, Issue 11, Page(s) 836–840

    MeSH term(s) Humans ; Psychotic Disorders/diagnosis ; Schizophrenia ; Machine Learning
    Language English
    Publishing date 2023-10-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.20220973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Identification of distinct clinical profiles and trajectories in individuals at high risk of developing psychosis: A latent profile analysis of the north American prodrome longitudinal study consortium-3 dataset.

    Bergé, Daniel / Carter, Cameron S / Smucny, Jason

    Early intervention in psychiatry

    2024  

    Abstract: Aim: People at clinical high risk (CHR) for psychosis are a heterogeneous population in regard to clinical presentation and outcome. It is unclear, however, if their baseline clinical characteristics can be used to construct orthogonal subgroups that ... ...

    Abstract Aim: People at clinical high risk (CHR) for psychosis are a heterogeneous population in regard to clinical presentation and outcome. It is unclear, however, if their baseline clinical characteristics can be used to construct orthogonal subgroups that differ in their clinical trajectory to provide early identification of individuals in need of tailored interventions.
    Methods: We used latent profile analysis (LPA) to determine the number of distinct clinical profiles within the CHR population using the NAPLS-3 dataset, focusing on the clinical features incorporated in the NAPLS psychosis risk calculator (including age, unusual thought content and suspiciousness, processing speed, verbal learning and memory function, social functioning decline, life events, childhood trauma, and family history of psychosis). We then conducted a between-profile comparisons of clinical trajectories based on psychotic and depressive symptoms as well as substance use disorder (SUD) related features over time.
    Results: Two distinct profiles emerged. One profile, comprising approximately 25% of the sample, was significantly older, displayed better cognitive performance, experienced more types of traumatic and undesirable life events, exhibited a greater decline in functioning in the past year, and was more likely to have relatives with psychosis. This group showed worse positive symptoms and SUD-related features over time, although groups did not differ in the proportion of individuals who developed psychosis.
    Conclusions: LPA results suggest CHRs can be segregated into two profiles with different clinical trajectories. Characterizing individuals within these clinical profiles may help understand the divergent outcomes of this population and ultimately facilitate the development of specialized interventions.
    Language English
    Publishing date 2024-02-13
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2272425-4
    ISSN 1751-7893 ; 1751-7885
    ISSN (online) 1751-7893
    ISSN 1751-7885
    DOI 10.1111/eip.13514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Spreads Its Wings.

    Carter, Cameron S

    Biological psychiatry. Cognitive neuroscience and neuroimaging

    2019  Volume 5, Issue 1, Page(s) 3

    MeSH term(s) Biological Psychiatry ; Cognitive Neuroscience ; Humans ; Journal Impact Factor ; Neuroimaging ; Peer Review, Research ; Periodicals as Topic
    Language English
    Publishing date 2019-12-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 2879089-3
    ISSN 2451-9030 ; 2451-9022
    ISSN (online) 2451-9030
    ISSN 2451-9022
    DOI 10.1016/j.bpsc.2019.12.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A

    Smucny, Jason / Carter, Cameron S / Maddock, Richard J

    Biological psychiatry. Cognitive neuroscience and neuroimaging

    2023  Volume 9, Issue 2, Page(s) 137–145

    Abstract: Background: The neurobiology of treatment-resistant schizophrenia (TRS) is poorly understood, and meta-analytic consensus regarding magnetic resonance spectroscopic profiles of glutamate, choline-containing compounds, myo-inositol, and other metabolites ...

    Abstract Background: The neurobiology of treatment-resistant schizophrenia (TRS) is poorly understood, and meta-analytic consensus regarding magnetic resonance spectroscopic profiles of glutamate, choline-containing compounds, myo-inositol, and other metabolites in the condition is lacking.
    Methods: In this meta-analysis, we examined published findings for N-acetylaspartate, choline-containing compounds (phosphocholine+glycerophosphocholine), myo-inositol, creatine+phosphocreatine, glutamate, and glutamate+glutamine in the anterior cingulate cortex and dorsal striatum in people with TRS versus non-TRS as well as TRS versus healthy control participants (HCs) and TRS versus ultra TRS (i.e., TRS with clozapine resistance). A MEDLINE search revealed 9 articles including 239 people with pooled TRS and ultra TRS, 59 with ultra TRS, 175 with non-TRS, and 153 (HCs) that met meta-analytic criteria.
    Results: Significant effects included higher anterior cingulate cortex phosphocholine+glycerophosphocholine and myo-inositol in the pooled TRS and ultra TRS group than in both the non-TRS group and HCs as well as higher dorsal striatal phosphocholine+glycerophosphocholine in ultra TRS versus HCs, but no differences in other regional metabolites.
    Conclusions: The observed metabolite profile in TRS (higher phosphocholine+glycerophosphocholine and myo-inositol signal) is consistent with the hypothesis that TRS has a neuroinflammatory component, although this meta-analysis is not a critical test of that hypothesis. A similar profile is seen in healthy aging, which is known to involve increased neuroinflammation and glial activation. Because the overall number of datasets was low, however, results should be considered preliminary and highlight the need for additional studies of brain metabolites in TRS and their possible association with inflammatory processes.
    MeSH term(s) Humans ; Schizophrenia/drug therapy ; Schizophrenia/metabolism ; Choline/metabolism ; Phosphorylcholine ; Magnetic Resonance Spectroscopy ; Glutamic Acid/metabolism ; Inositol/metabolism
    Chemical Substances Choline (N91BDP6H0X) ; Phosphorylcholine (107-73-3) ; Glutamic Acid (3KX376GY7L) ; Inositol (4L6452S749)
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2879089-3
    ISSN 2451-9030 ; 2451-9022
    ISSN (online) 2451-9030
    ISSN 2451-9022
    DOI 10.1016/j.bpsc.2023.10.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Can Pharmacological Augmentation of Cognitive Training Remediate Age-Related Cognitive Decline?

    Smucny, Jason / Carter, Cameron S

    The American journal of psychiatry

    2020  Volume 177, Issue 6, Page(s) 485–487

    MeSH term(s) Animals ; Attention Deficit Disorder with Hyperactivity ; Cognition ; Cognitive Dysfunction ; Drosophila ; Intellectual Disability ; Locomotion
    Language English
    Publishing date 2020-06-26
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280045-7
    ISSN 1535-7228 ; 0002-953X
    ISSN (online) 1535-7228
    ISSN 0002-953X
    DOI 10.1176/appi.ajp.2020.20040377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.30: Show issues Location:
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  8. Article ; Online: As the Field Matures … We Begin.

    Carter, Cameron S

    Biological psychiatry. Cognitive neuroscience and neuroimaging

    2016  Volume 1, Issue 1, Page(s) 3–4

    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 2879089-3
    ISSN 2451-9030 ; 2451-9022
    ISSN (online) 2451-9030
    ISSN 2451-9022
    DOI 10.1016/j.bpsc.2015.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clusters, Dimensions, and Hierarchies: Finding a Path Forward for the Neuroscience of Mental Disorders?

    Carter, Cameron S

    Biological psychiatry. Cognitive neuroscience and neuroimaging

    2017  Volume 3, Issue 1, Page(s) 2–3

    MeSH term(s) Cognitive Neuroscience ; Humans ; Neuroimaging ; Periodicals as Topic ; Psychopathology ; Research Design
    Language English
    Publishing date 2017-11-24
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2879089-3
    ISSN 2451-9030 ; 2451-9022
    ISSN (online) 2451-9030
    ISSN 2451-9022
    DOI 10.1016/j.bpsc.2017.11.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Altered Associations Between Task Performance and Dorsolateral Prefrontal Cortex Activation During Cognitive Control in Schizophrenia.

    Smucny, Jason / Hanks, Timothy D / Lesh, Tyler A / Carter, Cameron S

    Biological psychiatry. Cognitive neuroscience and neuroimaging

    2023  Volume 8, Issue 10, Page(s) 1050–1057

    Abstract: Background: Dysfunctional cognitive control processes are now well understood to be core features of schizophrenia (SZ). A body of work suggests that the dorsolateral prefrontal cortex (DLPFC) plays a critical role in explaining cognitive control ... ...

    Abstract Background: Dysfunctional cognitive control processes are now well understood to be core features of schizophrenia (SZ). A body of work suggests that the dorsolateral prefrontal cortex (DLPFC) plays a critical role in explaining cognitive control disruptions in SZ. Here, we examined relationships between DLPFC activation and drift rate (DR), a model-based performance measure that combines reaction time and accuracy, in people with SZ and healthy control (HC) participants.
    Methods: One hundred fifty-one people with recent-onset SZ spectrum disorders and 118 HC participants performed the AX-Continuous Performance Task during functional magnetic resonance imaging scanning. Proactive cognitive control-associated activation was extracted from left and right DLPFC regions of interest. Individual behavior was fit using a drift diffusion model, allowing DR to vary between task conditions.
    Results: Behaviorally, people with SZ showed significantly lower DRs than HC participants, particularly during high proactive control trial types ("B" trials). Recapitulating previous findings, the SZ group also demonstrated reduced cognitive control-associated DLPFC activation compared with HC participants. Furthermore, significant group differences were also observed in the relationship between left and right DLPFC activation with DR, such that positive relationships between DR and activation were found in HC participants but not in people with SZ.
    Conclusions: These results suggest that DLPFC activation is less associated with cognitive control-related behavioral performance enhancements in SZ. Potential mechanisms and implications are discussed.
    MeSH term(s) Humans ; Schizophrenia ; Dorsolateral Prefrontal Cortex ; Prefrontal Cortex ; Task Performance and Analysis ; Cognition
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2879089-3
    ISSN 2451-9030 ; 2451-9022
    ISSN (online) 2451-9030
    ISSN 2451-9022
    DOI 10.1016/j.bpsc.2023.05.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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