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  1. Book: Phase-separated biomolecular condensates

    Zhou, Huan-Xiang / Spille, Jan-Hendrik / Banerjee, Priya

    (Methods in molecular biology ; 2563 ; Springer protocols)

    2023  

    Author's details edited by Huan-Xiang Zhou, Jan-Hendrik Spille, Priya Banerjee
    Series title Methods in molecular biology ; 2563
    Springer protocols
    Collection
    Keywords Cell organelles
    Subject code 571.65
    Language English
    Size xiv, 449 Seiten, Illustrationen, 26 cm
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT021570041
    ISBN 978-1-0716-2662-7 ; 9781071626634 ; 1-0716-2662-0 ; 1071626639
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -2563- not available for loan Lesesaal EG

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  2. Article ; Online: Power Law in a Bounded Range: Estimating the Lower and Upper Bounds from Sample Data.

    Zhou, Huan-Xiang

    ArXiv

    2023  

    Abstract: Power law distributions are widely observed in chemical physics, geophysics, biology, and beyond. The independent variable x of these distributions has an obligatory lower bound and in many cases also an upper bound. Estimating these bounds from sample ... ...

    Abstract Power law distributions are widely observed in chemical physics, geophysics, biology, and beyond. The independent variable x of these distributions has an obligatory lower bound and in many cases also an upper bound. Estimating these bounds from sample data is notoriously difficult, with a recent method involving O(N^3) operations, where N denotes sample size. Here I develop an approach for estimating the lower and upper bounds that involves O(N) operations. The approach centers on calculating the mean values, x_min and x_max, of the smallest x and the largest x in N-point samples. A fit of x_min or x_max as a function of N yields the estimate for the lower or upper bound. Application to synthetic data demonstrates the accuracy and reliability of this approach.
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Preprint
    ISSN 2331-8422
    ISSN (online) 2331-8422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Calculating Structure Factors of Protein Solutions by Atomistic Modeling of Protein-Protein Interactions.

    Qin, Sanbo / Zhou, Huan-Xiang

    bioRxiv : the preprint server for biology

    2024  

    Abstract: We present a method, FMAPS(q), for calculating the structure factor, ...

    Abstract We present a method, FMAPS(q), for calculating the structure factor,
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.03.27.587040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Power law in a bounded range: Estimating the lower and upper bounds from sample data.

    Zhou, Huan-Xiang

    The Journal of chemical physics

    2022  Volume 158, Issue 19

    Abstract: Power law distributions are widely observed in chemical physics, geophysics, biology, and beyond. The independent variable x of these distributions has an obligatory lower bound and, in many cases, also an upper bound. Estimating these bounds from sample ...

    Abstract Power law distributions are widely observed in chemical physics, geophysics, biology, and beyond. The independent variable x of these distributions has an obligatory lower bound and, in many cases, also an upper bound. Estimating these bounds from sample data is notoriously difficult, with a recent method involving O(N3) operations, where N denotes sample size. Here I develop an approach for estimating the lower and upper bounds that involve O(N) operations. The approach centers on calculating the mean values, x̂min and x̂max, of the smallest x and the largest x in N-point samples. A fit of x̂min or x̂max as a function of N yields the estimate for the lower or upper bound. Application to synthetic data demonstrates the accuracy and reliability of this approach.
    Language English
    Publishing date 2022-10-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0151614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

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  5. Book: Zhong yao ying xiang xiao hua hu xi xi tong huo xing cheng fen

    Zhou, J

    Active components on digestive and respiratory systems in TCM

    (Zhong yao yao li huo xing cheng fen cong shu =)

    2012  

    Title variant Active components on digestive and respiratory systems in TCM
    Author's details Zhou Jiaju, Xie Guirong, Yan Xinjian bian zhu
    Series title Zhong yao yao li huo xing cheng fen cong shu =
    MeSH term(s) Gastrointestinal Agents/analysis ; Respiratory System Agents/analysis ; Drugs, Chinese Herbal/analysis
    Language Chinese
    Size xii, 401 p. :, ill
    Edition Di 1 ban.
    Publisher Ke xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787030338297 ; 7030338294
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article: Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch.

    Hu, Guodong / Zhou, Huan-Xiang

    bioRxiv : the preprint server for biology

    2023  

    Abstract: The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. ... ...

    Abstract The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. Mg
    Language English
    Publishing date 2023-03-12
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.03.12.532287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Viscoelasticity of biomolecular condensates conforms to the Jeffreys model.

    Zhou, Huan-Xiang

    The Journal of chemical physics

    2021  Volume 154, Issue 4, Page(s) 41103

    Abstract: Biomolecular condensates, largely by virtue of their material properties, are revolutionizing biology, and yet, the physical understanding of these properties is lagging. Here, I show that the viscoelasticity of condensates can be captured by a simple ... ...

    Abstract Biomolecular condensates, largely by virtue of their material properties, are revolutionizing biology, and yet, the physical understanding of these properties is lagging. Here, I show that the viscoelasticity of condensates can be captured by a simple model, comprising a component where shear relaxation is an exponential function (with time constant τ
    MeSH term(s) Animals ; Caenorhabditis elegans/chemistry ; Caenorhabditis elegans Proteins/chemistry ; Models, Chemical ; Particle Size ; Potassium Chloride/chemistry ; RNA-Binding Proteins/chemistry ; Salts/chemistry ; Viscosity
    Chemical Substances Caenorhabditis elegans Proteins ; PGL-3 protein, C elegans ; RNA-Binding Proteins ; Salts ; Potassium Chloride (660YQ98I10)
    Language English
    Publishing date 2021-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0038916
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

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  8. Article ; Online: Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch.

    Hu, Guodong / Zhou, Huan-Xiang

    Communications biology

    2023  Volume 6, Issue 1, Page(s) 791

    Abstract: The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. ... ...

    Abstract The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. Mg
    MeSH term(s) Nucleic Acid Conformation ; Riboswitch ; Magnesium ; S-Adenosylmethionine/chemistry ; S-Adenosylmethionine/metabolism ; Ligands ; RNA/chemistry ; Ions
    Chemical Substances Riboswitch ; Magnesium (I38ZP9992A) ; S-Adenosylmethionine (7LP2MPO46S) ; Ligands ; RNA (63231-63-0) ; Ions
    Language English
    Publishing date 2023-07-31
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-023-05175-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Predicting the Sequence-Dependent Backbone Dynamics of Intrinsically Disordered Proteins.

    Qin, Sanbo / Zhou, Huan-Xiang

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Dynamics is a crucial link between sequence and function for intrinsically disordered proteins (IDPs). NMR spin relaxation is a powerful technique for characterizing the sequence-dependent backbone dynamics of IDPs. Of particular interest is ... ...

    Abstract Dynamics is a crucial link between sequence and function for intrinsically disordered proteins (IDPs). NMR spin relaxation is a powerful technique for characterizing the sequence-dependent backbone dynamics of IDPs. Of particular interest is the
    Language English
    Publishing date 2023-02-03
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.02.02.526886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Shape recovery of deformed biomolecular droplets: Dependence on condensate viscoelasticity.

    Zhou, Huan-Xiang

    The Journal of chemical physics

    2021  Volume 155, Issue 14, Page(s) 145102

    Abstract: A theoretical study on the shape dynamics of phase-separated biomolecular droplets is presented, highlighting the importance of condensate viscoelasticity. Previous studies on shape dynamics have modeled biomolecular condensates as purely viscous, but ... ...

    Abstract A theoretical study on the shape dynamics of phase-separated biomolecular droplets is presented, highlighting the importance of condensate viscoelasticity. Previous studies on shape dynamics have modeled biomolecular condensates as purely viscous, but recent data have shown them to be viscoelastic. Here, we present an exact analytical solution for the shape recovery dynamics of deformed biomolecular droplets. The shape recovery of viscous droplets has an exponential time dependence, with the time constant given by the "viscocapillary" ratio, i.e., viscosity over interfacial tension. In contrast, the shape recovery dynamics of viscoelastic droplets is multi-exponential, with shear relaxation yielding additional time constants. During shape recovery, viscoelastic droplets exhibit shear thickening (increase in apparent viscosity) at fast shear relaxation rates but shear thinning (decrease in apparent viscosity) at slow shear relaxation rates. These results highlight the importance of viscoelasticity and expand our understanding of how material properties affect condensate dynamics in general, including aging.
    MeSH term(s) Biomolecular Condensates/chemistry ; Elasticity ; Models, Chemical ; Surface Tension ; Viscosity
    Language English
    Publishing date 2021-09-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0064247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

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