LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 564

Search options

  1. Article ; Online: Penile edema in a child.

    Etcheverry, Maria J / Millan, Sarah H / Hsieh, Michael H / Cardis, Michael A

    Pediatric dermatology

    2024  

    Language English
    Publishing date 2024-02-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15548
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Photocatalytic Aryl Sulfide Oxidation Using 4-Nitrophenylacetylene-Modified Cu

    Hsieh, Mu-Han / Su, Zhe-Hong / Wu, Er-Ting / Huang, Michael H

    ACS applied materials & interfaces

    2023  Volume 15, Issue 9, Page(s) 11662–11669

    Abstract: 4-Nitrophenylacetylene-functionalized ... ...

    Abstract 4-Nitrophenylacetylene-functionalized Cu
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.2c20120
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Automatic and real-time tissue sensing for autonomous intestinal anastomosis using hybrid MLP-DC-CNN classifier-based optical coherence tomography.

    Wang, Yaning / Wei, Shuwen / Zuo, Ruizhi / Kam, Michael / Opfermann, Justin D / Sunmola, Idris / Hsieh, Michael H / Krieger, Axel / Kang, Jin U

    Biomedical optics express

    2024  Volume 15, Issue 4, Page(s) 2543–2560

    Abstract: Anastomosis is a common and critical part of reconstructive procedures within gastrointestinal, urologic, and gynecologic surgery. The use of autonomous surgical robots such as the smart tissue autonomous robot (STAR) system demonstrates an improved ... ...

    Abstract Anastomosis is a common and critical part of reconstructive procedures within gastrointestinal, urologic, and gynecologic surgery. The use of autonomous surgical robots such as the smart tissue autonomous robot (STAR) system demonstrates an improved efficiency and consistency of the laparoscopic small bowel anastomosis over the current da Vinci surgical system. However, the STAR workflow requires auxiliary manual monitoring during the suturing procedure to avoid missed or wrong stitches. To eliminate this monitoring task from the operators, we integrated an optical coherence tomography (OCT) fiber sensor with the suture tool and developed an automatic tissue classification algorithm for detecting missed or wrong stitches in real time. The classification results were updated and sent to the control loop of STAR robot in real time. The suture tool was guided to approach the object by a dual-camera system. If the tissue inside the tool jaw was inconsistent with the desired suture pattern, a warning message would be generated. The proposed hybrid multilayer perceptron dual-channel convolutional neural network (MLP-DC-CNN) classification platform can automatically classify eight different abdominal tissue types that require different suture strategies for anastomosis. In MLP, numerous handcrafted features (∼1955) were utilized including optical properties and morphological features of one-dimensional (1D) OCT A-line signals. In DC-CNN, intensity-based features and depth-resolved tissues' attenuation coefficients were fully exploited. A decision fusion technique was applied to leverage the information collected from both classifiers to further increase the accuracy. The algorithm was evaluated on 69,773 testing A-line data. The results showed that our model can classify the 1D OCT signals of small bowels in real time with an accuracy of 90.06%, a precision of 88.34%, and a sensitivity of 87.29%, respectively. The refresh rate of the displayed A-line signals was set as 300 Hz, the maximum sensing depth of the fiber was 3.6 mm, and the running time of the image processing algorithm was ∼1.56 s for 1,024 A-lines. The proposed fully automated tissue sensing model outperformed the single classifier of CNN, MLP, or SVM with optimized architectures, showing the complementarity of different feature sets and network architectures in classifying intestinal OCT A-line signals. It can potentially reduce the manual involvement of robotic laparoscopic surgery, which is a crucial step towards a fully autonomous STAR system.
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2572216-5
    ISSN 2156-7085
    ISSN 2156-7085
    DOI 10.1364/BOE.521652
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: The Symposium for International Research and Innovations in Schistosomiasis (SIRIS): hopes for a bright new star in the skyscape of schistosomiasis research.

    Hsieh, Michael H

    International journal for parasitology

    2016  Volume 46, Issue 7, Page(s) 383–384

    Language English
    Publishing date 2016
    Publishing country England
    Document type Editorial
    ZDB-ID 120518-3
    ISSN 1879-0135 ; 0020-7519
    ISSN (online) 1879-0135
    ISSN 0020-7519
    DOI 10.1016/j.ijpara.2016.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Photocatalytic Aryl Sulfide Oxidation Using 4‑Nitrophenylacetylene-Modified Cu₂O Crystals

    Hsieh, Mu-Han / Su, Zhe-Hong / Wu, Er-Ting / Huang, Michael H.

    ACS Applied Materials & Interfaces. 2023 Feb. 23, v. 15, no. 9 p.11662-11669

    2023  

    Abstract: ... light-emitting diode (LED), the reaction can be completed in 12 h with a water and methanol mixed ...

    Abstract 4-Nitrophenylacetylene-functionalized Cu₂O rhombic dodecahedra and cubes have been used to photocatalyze aryl sulfide oxidation generating aryl sulfoxides. With an oxygen supply and light from a blue light-emitting diode (LED), the reaction can be completed in 12 h with a water and methanol mixed solution. Generally high product yields and excellent product selectivity of sulfoxides over sulfones were achieved. In particular, a thioanisole to methyl phenyl sulfoxide yield of 98% was obtained. A mechanistic study has revealed that photogenerated electrons, holes, and superoxide radicals are involved in the oxidation reaction. The benefit of simple photocatalyst preparation and molecular functionalization to boost catalytic performance shows that surface-controlled ionic solids can be very effective photocatalysts for some organic transformations.
    Keywords light emitting diodes ; methanol ; oxidation ; oxygen ; photocatalysis ; photocatalysts ; sulfides ; sulfoxides ; aryl sulfide oxidation ; cuprous oxide ; semiconductor ; surface functionalization
    Language English
    Dates of publication 2023-0223
    Size p. 11662-11669.
    Publishing place American Chemical Society
    Document type Article ; Online
    ISSN 1944-8252
    DOI 10.1021/acsami.2c20120
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  6. Article ; Online: Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from testicular fibroblasts.

    Harancher, Mitchell R / Sukhwani, Meena / Castro, Carlos A / Hsieh, Michael H / Orwig, Kyle E

    Stem cell research

    2023  Volume 73, Page(s) 103257

    Abstract: Curative bone marrow transplantation (BMT) therapies for sickle cell disease (SCD) can cause infertility. The Fertility Preservation Program (FPP) in Pittsburgh cryopreserves testicular tissues for SCD patients prior to BMT in anticipation that those ... ...

    Abstract Curative bone marrow transplantation (BMT) therapies for sickle cell disease (SCD) can cause infertility. The Fertility Preservation Program (FPP) in Pittsburgh cryopreserves testicular tissues for SCD patients prior to BMT in anticipation that those tissues can be thawed in the future and matured to produce sperm. Here, we generated and validated two isogenic patient-derived induced pluripotent stem cell (iPSC) lines from testicular biopsy fibroblasts of a 12-year-old SCD patient.
    MeSH term(s) Humans ; Male ; Child ; Induced Pluripotent Stem Cells/pathology ; Semen ; Bone Marrow Transplantation ; Anemia, Sickle Cell/pathology ; Fibroblasts/pathology
    Language English
    Publishing date 2023-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2393143-7
    ISSN 1876-7753 ; 1873-5061
    ISSN (online) 1876-7753
    ISSN 1873-5061
    DOI 10.1016/j.scr.2023.103257
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Editorial Comment.

    Hsieh, Michael H

    The Journal of urology

    2015  Volume 194, Issue 5, Page(s) 1424

    MeSH term(s) Cell Transplantation/methods ; Fertility ; Fertility Preservation/methods ; Humans ; Infertility, Male/prevention & control ; Male ; Neoplasms/diagnosis ; Testis/pathology
    Language English
    Publishing date 2015-11
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2015.04.126
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Editorial Comment.

    Hsieh, Michael H

    Urology

    2015  Volume 86, Issue 4, Page(s) 809

    MeSH term(s) Bladder Exstrophy/surgery ; Humans ; Male ; Reconstructive Surgical Procedures/methods ; Scrotum/surgery ; Surgical Flaps ; Urologic Surgical Procedures, Male/methods
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2015.04.056
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Obicetrapib: Reversing the Tide of CETP Inhibitor Disappointments.

    Kastelein, John J P / Hsieh, Andrew / Dicklin, Mary R / Ditmarsch, Marc / Davidson, Michael H

    Current atherosclerosis reports

    2023  Volume 26, Issue 2, Page(s) 35–44

    Abstract: Purpose of review: To discuss the history of cardiovascular outcomes trials of cholesteryl ester transfer protein (CETP) inhibitors and to describe obicetrapib, a next-generation, oral, once-daily, low-dose CETP inhibitor in late-stage development for ... ...

    Abstract Purpose of review: To discuss the history of cardiovascular outcomes trials of cholesteryl ester transfer protein (CETP) inhibitors and to describe obicetrapib, a next-generation, oral, once-daily, low-dose CETP inhibitor in late-stage development for dyslipidemia and atherosclerotic cardiovascular disease (ASCVD).
    Recent findings: Phase 1 and 2 trials have evaluated the safety and lipid/lipoprotein effects of obicetrapib as monotherapy, in conjunction with statins, on top of high-intensity statins (HIS), and with ezetimibe on top of HIS. In ROSE2, 10 mg obicetrapib monotherapy and combined with 10 mg ezetimibe, each on top of HIS, significantly reduced low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), apolipoprotein B, total LDL particles, small LDL particles, small, dense LDL-C, and lipoprotein (a), and increased HDL-C. Phase 3 pivotal registration trials including a cardiovascular outcomes trial are underway. Obicetrapib has an excellent safety and tolerability profile and robustly lowers atherogenic lipoproteins and raises HDL-C. As such, obicetrapib may be a promising agent for the treatment of ASCVD.
    MeSH term(s) Humans ; Cholesterol Ester Transfer Proteins ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Cholesterol, LDL ; Cholesterol, HDL ; Atherosclerosis/drug therapy ; Lipoproteins ; Ezetimibe
    Chemical Substances Cholesterol Ester Transfer Proteins ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Cholesterol, LDL ; Cholesterol, HDL ; Lipoproteins ; Ezetimibe (EOR26LQQ24) ; CETP protein, human
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057369-8
    ISSN 1534-6242 ; 1523-3804
    ISSN (online) 1534-6242
    ISSN 1523-3804
    DOI 10.1007/s11883-023-01184-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Understanding Urogenital Schistosomiasis-Related Bladder Cancer: An Update.

    Ishida, Kenji / Hsieh, Michael H

    Frontiers in medicine

    2018  Volume 5, Page(s) 223

    Abstract: Infection ... ...

    Abstract Infection with
    Language English
    Publishing date 2018-08-10
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2018.00223
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top