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  1. Article ; Online: Cardioembolic Stroke in Sinus of Valsalva Aneurysm, A Case Report.

    Thomas, Vineeth V / Thomas, Joel M / Iyadurai, Ramya

    Neurology India

    2023  Volume 71, Issue 5, Page(s) 998–1001

    Abstract: A case of cardioembolic stroke in a patient with sinus of Valsalva aneurysm. The patient presented with chief complaints of syncope, with slurring of speech and a history of deviation of angle of mouth to the right side, which resolved over one day. ... ...

    Abstract A case of cardioembolic stroke in a patient with sinus of Valsalva aneurysm. The patient presented with chief complaints of syncope, with slurring of speech and a history of deviation of angle of mouth to the right side, which resolved over one day. Examination revealed no focal neurological deficit. CT Brain revealed a lacunar infarct over the left frontal cortex. Echocardiography showed sinus of Valsalva aneurysm of the non-coronary cusp. Hence a diagnosis of cardioembolic stroke secondary to thrombus present in the sinus of Valsalva of the aneurysm was considered. This is a rare presentation of Sinus of Valsalva as a cardioembolic stroke.
    MeSH term(s) Humans ; Aortic Rupture/complications ; Aortic Rupture/diagnosis ; Sinus of Valsalva/diagnostic imaging ; Embolic Stroke/complications ; Aortic Aneurysm/complications ; Echocardiography/adverse effects
    Language English
    Publishing date 2023-10-21
    Publishing country India
    Document type Case Reports
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.388106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Weight gain and Thyroid in women: The coexisting confounders.

    Thomas, Vineeth / Rallapalli, Sindhusree / Kapoor, Nitin / Kalra, Sanjay

    JPMA. The Journal of the Pakistan Medical Association

    2022  Volume 72, Issue 9, Page(s) 1871–1873

    Abstract: Hypothyroidism and obesity are common coexisting illnesses which have an impact on each other. Data from India suggests that about a third of individuals with obesity have overt hypothyroidism and about one-tenth have subclinical hypothyroidism. Multiple ...

    Abstract Hypothyroidism and obesity are common coexisting illnesses which have an impact on each other. Data from India suggests that about a third of individuals with obesity have overt hypothyroidism and about one-tenth have subclinical hypothyroidism. Multiple mechanisms have described how both thyroid and obesity could have a significant impact on each other. A moderately elevated TSH, elevated T3 and a lower T4 is classically described thyroid dysfunction in patients with obesity. This article will detail the epidemiology, pathogenesis and the clinical implications of weight gain and thyroid dysfunction with a special focus on women.
    MeSH term(s) Humans ; Female ; Thyrotropin ; Hypothyroidism/complications ; Thyroid Diseases/complications ; Thyroid Diseases/epidemiology ; Weight Gain ; Obesity/epidemiology ; Obesity/complications
    Chemical Substances Thyrotropin (9002-71-5)
    Language English
    Publishing date 2022-10-24
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
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  3. Article ; Online: Vocal repertoire of

    Srigyan, Megha / Samad, Abdus / Singh, Abhishek / Karan, Jyotsna / Chandra, Abhishek / Sinha, Pooja Gokhale / Kumar, Vineeth / Das, Sandeep / Thomas, Ashish / Suyesh, Robin

    PeerJ

    2024  Volume 12, Page(s) e16903

    Abstract: Advertisement calls in frogs have evolved to be species-specific signals of recognition and are therefore considered an essential component of integrative taxonomic approaches to identify species and delineate their distribution range. The species rich ... ...

    Abstract Advertisement calls in frogs have evolved to be species-specific signals of recognition and are therefore considered an essential component of integrative taxonomic approaches to identify species and delineate their distribution range. The species rich genus
    MeSH term(s) Humans ; Animals ; Sri Lanka ; Acoustics ; Anura/anatomy & histology ; India ; Vocalization, Animal
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.16903
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  4. Article ; Online: Review of current evidence in management of oleander poisoning

    Vineeth Varghese Thomas / Nalini Newbigging / Jacob Johnson / Murugabharathy Kalimuthu / Karthik Gunasekaran / Ramya Iyadurai

    Current Medical Issues, Vol 20, Iss 2, Pp 82-

    2022  Volume 88

    Abstract: India has a high incidence of poisoning, especially in the rural setting with plant-based compounds being used as a common agent. Oleander poisoning is a common shrub seen throughout the tropics including nearly all parts of India. It continues to remain ...

    Abstract India has a high incidence of poisoning, especially in the rural setting with plant-based compounds being used as a common agent. Oleander poisoning is a common shrub seen throughout the tropics including nearly all parts of India. It continues to remain an important cause for both accidental and deliberate self-harm in the community with all parts of the plant containing toxin sufficient to cause poisoning. There is enough evidence to show that oleander poisoning continues as one of the more common plant-based causes for poisoning. This review looks at the common management principles and provides an update on the currently available treatment strategies and evidence for them.
    Keywords nerium oleander ; oleander ; plant toxin ; thevetia peruviana ; Medicine ; R
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Bio-Inspired Dynamically Morphing Microelectronics toward High-Density Energy Applications and Intelligent Biomedical Implants.

    Merces, Leandro / Ferro, Letícia Mariê Minatogau / Thomas, Aleena / Karnaushenko, Dmitriy D / Luo, Yumin / Egunov, Aleksandr I / Zhang, Wenlan / Bandari, Vineeth K / Lee, Yeji / McCaskill, John S / Zhu, Minshen / Schmidt, Oliver G / Karnaushenko, Daniil

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2313327

    Abstract: Choreographing the adaptive shapes of patterned surfaces to exhibit designable mechanical interactions with their environment remains an intricate challenge. Here, a novel category of strain-engineered dynamic-shape materials, empowering diverse multi- ... ...

    Abstract Choreographing the adaptive shapes of patterned surfaces to exhibit designable mechanical interactions with their environment remains an intricate challenge. Here, a novel category of strain-engineered dynamic-shape materials, empowering diverse multi-dimensional shape modulations that are combined to form fine-grained adaptive microarchitectures is introduced. Using micro-origami tessellation technology, heterogeneous materials are provided with strategic creases featuring stimuli-responsive micro-hinges that morph precisely upon chemical and electrical cues. Freestanding multifaceted foldable packages, auxetic mesosurfaces, and morphable cages are three of the forms demonstrated herein of these complex 4-dimensional (4D) metamaterials. These systems are integrated in dual proof-of-concept bioelectronic demonstrations: a soft foldable supercapacitor enhancing its power density (≈108 mW cm
    Language English
    Publishing date 2024-02-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202313327
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  6. Article ; Online: Plasma Electroless Reduction: A Green Process for Designing Metallic Nanostructure Interfaces onto Polymeric Surfaces and 3D Scaffolds.

    Vijayan, Vineeth M / Walker, Melissa / Pillai, Renjith R / Moreno, Gerardo Hernandez / Vohra, Yogesh K / Morris, J Jeffrey / Thomas, Vinoy

    ACS applied materials & interfaces

    2022  Volume 14, Issue 22, Page(s) 25065–25079

    Abstract: The design of metal nanoparticle-modified polymer surfaces in a green and scalable way is both desirable and highly challenging. Herein, a new green low-temperature plasma- ... ...

    Abstract The design of metal nanoparticle-modified polymer surfaces in a green and scalable way is both desirable and highly challenging. Herein, a new green low-temperature plasma-based
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.2c01195
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  7. Article ; Online: Quantitative susceptibility mapping from basal ganglia and related structures: correlation with disease severity in progressive supranuclear palsy.

    Krishnan, Syam / George, Sneha Susan / Radhakrishnan, Vineeth / Raghavan, Sheelakumari / Thomas, Bejoy / Thulaseedharan, Jissa Vinoda / Puthenveedu, Divya Kalikavil

    Acta neurologica Belgica

    2023  Volume 124, Issue 1, Page(s) 151–160

    Abstract: Objective: We examined whether mean magnetic susceptibility values from deep gray matter structures in patients with progressive supranuclear palsy (PSP) differed from those in patients with Parkinson's disease (PD) and healthy volunteers, and ... ...

    Abstract Objective: We examined whether mean magnetic susceptibility values from deep gray matter structures in patients with progressive supranuclear palsy (PSP) differed from those in patients with Parkinson's disease (PD) and healthy volunteers, and correlated with the PSP rating scale.
    Methods: Head of caudate nucleus, putamen, globus pallidus, substantia nigra and red nucleus were the regions of interest. Mean susceptibility values from these regions in PSP patients were estimated using quantitative susceptibility mapping. Correlations with clinical severity of disease as measured by the PSP rating scale were examined. The mean susceptibility values were also compared with those from healthy volunteers and age- and disease duration-matched patients with PD.
    Results: Data from 26 healthy volunteers, 26 patients with PD and 27 patients with PSP, were analysed. Patients with PSP had higher mean susceptibility values from all regions of interest when compared to both the other groups. The PSP rating scale scores correlated strongly with mean susceptibility values from the red nucleus and moderately with those from the putamen and substantia nigra. The scores did not correlate with mean susceptibility values from the caudate nucleus or globus pallidus. In patients with PD, the motor deficits correlated moderately with mean susceptibility values from substantia nigra.
    Conclusions: In patients with PSP, mean susceptibility values indicating the severity of mineralization of basal ganglia and related structures correlate with disease severity, the correlation of red nucleus being the strongest. Further studies are warranted to explore whether mean susceptibility values could serve as biomarkers for PSP.
    MeSH term(s) Humans ; Supranuclear Palsy, Progressive/diagnostic imaging ; Parkinson Disease ; Substantia Nigra/diagnostic imaging ; Caudate Nucleus ; Patient Acuity ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-08-14
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-023-02352-5
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  8. Article: Cerebellar and basal ganglia structural connections in humans: Effect of aging and relation with memory and learning.

    Radhakrishnan, Vineeth / Gallea, Cecile / Valabregue, Romain / Krishnan, Syam / Kesavadas, Chandrasekharan / Thomas, Bejoy / James, Praveen / Menon, Ramshekhar / Kishore, Asha

    Frontiers in aging neuroscience

    2023  Volume 15, Page(s) 1019239

    Abstract: Introduction: The cerebellum and basal ganglia were initially considered anatomically distinct regions, each connected : Methods: In this study, we validated and expanded the previous findings of the structural connectivity within the cerebellum- ... ...

    Abstract Introduction: The cerebellum and basal ganglia were initially considered anatomically distinct regions, each connected
    Methods: In this study, we validated and expanded the previous findings of the structural connectivity within the cerebellum-basal ganglia subcortical network, in a larger dataset of 64 subjects, across different age ranges. Tractography and fixel-based analysis were performed on the 3 T diffusion-weighted dataset using Mrtrix3 software, considering fiber density and cross-section as indicators of axonal integrity. Tractography of the well-established cerebello-thalamo-cortical tract was conducted as a control. We tested the relationship between the structural white matter integrity of these connections with aging and with the performance in different domains of Addenbrooke's Cognitive Examination.
    Results: Tractography analysis isolated connections from the dentate nucleus to the contralateral putamen
    Conclusion: We validated the structural connectivity within the cerebellum-basal ganglia reciprocal network, in a larger dataset of human subjects, across wider age range. The structural features of the subcortical cerebello-basal ganglia tracts in human subjects display age-related neurodegeneration. Individual morphological variability of cerebellar tracts to the striatum and prefrontal cortex was associated with different cognitive functions, suggesting a functional contribution of cerebellar tracts to cognitive decline with aging. This study offers new perspectives to consider the functional role of these pathways in motor learning and the pathophysiology of movement disorders involving the cerebellum and striatum.
    Language English
    Publishing date 2023-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2023.1019239
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  9. Article: The genetic landscape of COVID-19: A South Asian perspective.

    Thomas, Vineeth / Audsley, Jennifer / Kapoor, Nitin

    JPMA. The Journal of the Pakistan Medical Association

    2020  Volume 70Suppl 3, Issue 5, Page(s) S38–S43

    Abstract: COVID-19 has taken the world by storm in the ongoing pandemic. The virus responsible for COVID-19 disease is 'severe acute respiratory syndrome coronavirus-2' SARS-CoV-2, an enveloped RNA beta-coronavirus from the family Coronaviridae. There have been ... ...

    Abstract COVID-19 has taken the world by storm in the ongoing pandemic. The virus responsible for COVID-19 disease is 'severe acute respiratory syndrome coronavirus-2' SARS-CoV-2, an enveloped RNA beta-coronavirus from the family Coronaviridae. There have been similar beta-coronavirus disease outbreaks previously: Severe acute respiratory syndrome (SARS - 2002) and Middle East respiratory syndrome (MERS - 2012) epidemics. SARS-CoV-2 origins have been traced to bat reservoirs. A virus with a high capacity for mutation, SARS-CoV-2 poses unique challenges both in the current form of disease control and management, while also leaving the door open for future novel diseases and pandemics. An understanding of the virion structure and genomic organisation will help us in understanding their origins and likely course of future evolution. Moreover, novel cost-effective methodologies for genetic surveillance may help in mitigating the emergence of these viral infections in future. In this manuscript, the authors have detailed the unique aspects of the SARS-CoV-2 virus genome and its clinical implications.
    MeSH term(s) Animals ; Asia ; Betacoronavirus/genetics ; COVID-19 ; Chiroptera/virology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Genome, Viral/genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation/genetics ; Mutation Rate ; Pandemics ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; RNA, Viral/genetics ; SARS-CoV-2 ; Virion/genetics
    Chemical Substances RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.5455/JPMA.09
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  10. Article ; Online: "Don't Forget the Eagles".

    Thomas, Joe / Viswam, Vineeth / Xavier, Anil Nellikkal

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2018  Volume 25, Issue 5, Page(s) e62

    MeSH term(s) Dissection/methods ; Female ; Humans ; Middle Aged ; Ossification, Heterotopic/diagnosis ; Ossification, Heterotopic/physiopathology ; Ossification, Heterotopic/surgery ; Temporal Bone/abnormalities ; Temporal Bone/diagnostic imaging ; Temporal Bone/physiopathology ; Temporal Bone/surgery ; Tomography, X-Ray Computed/methods ; Treatment Outcome
    Language English
    Publishing date 2018-04-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000000696
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