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  1. Article ; Online: Coaching in nursing: An integrative literature review.

    Richardson, Corianne / Wicking, Kristin / Biedermann, Narelle / Langtree, Tanya

    Nursing open

    2023  Volume 10, Issue 10, Page(s) 6635–6649

    Abstract: Aim: To understand the current application and benefits of coaching practice in nursing and identify potential areas for future research.: Design: An integrative literature review was conducted using Whittemore and Knalf integrative review methods.!## ...

    Abstract Aim: To understand the current application and benefits of coaching practice in nursing and identify potential areas for future research.
    Design: An integrative literature review was conducted using Whittemore and Knalf integrative review methods.
    Data sources: A search of the literature from Medline (PubMed) and CINHAL platform for abstracts and/or full-text articles from 2012 to 2022.
    Methods: A systematic approach was used to screen and analyse the literature. Inclusion and exclusion criteria were applied, a quality appraisal of the literature was undertaken and summarised into themes. Eighteen articles were selected, two articles were different aspects of the same studies. Coaching was found to have benefits to the individual related to performance, role effectiveness, role transitions and confidence in performing in the role. The outcomes for individuals add to the overall organisational benefits with performance, support, teamwork, communication and culture.
    Results: This literature review sought to understand the current use of coaching in nursing and identify any gaps in the application of coaching within the discipline. Supporting, developing staff knowledge and skills and nurturing nursing staff into the profession has occurred in several ways and evolved to include coaching. Coaching provides capabilities to enhance nursing leadership, performance improvement and to provide support to staff. The findings from this literature review found a need to conceptually define coaching in nursing and the opportunity to explore the use of coaching to support both the clinical and managerial workforce (job satisfaction, intention to stay and building resilience). The benefits of coaching in nursing extend beyond the leadership level and there is opportunity to extend the operationalisation of coaching practice and coaching training within the discipline of nursing. This integrative review explains how coaching has been utilised in nursing to be a valuable tool in developing nurse leaders and clinical staff.
    MeSH term(s) Humans ; Mentoring ; Nursing Staff ; Intention ; Leadership ; Clinical Competence
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2809556-X
    ISSN 2054-1058 ; 2054-1058
    ISSN (online) 2054-1058
    ISSN 2054-1058
    DOI 10.1002/nop2.1925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chemical analysis of additives included in fully formulated oils using high-performance liquid chromatography-tandem mass spectrometry.

    Basham, Vincent / Hancock, Tom / McKendrick, John / Tessarolo, Nathalia / Wicking, Chrissie

    Rapid communications in mass spectrometry : RCM

    2024  Volume 38, Issue 5, Page(s) e9682

    Abstract: Rationale: Fully formulated oils (FFOs) are chemically complex petrochemical products composed of base oil and additive mixtures that are employed in automotive engines to provide lubrication. In particular, the additive portion of FFOs is often ... ...

    Abstract Rationale: Fully formulated oils (FFOs) are chemically complex petrochemical products composed of base oil and additive mixtures that are employed in automotive engines to provide lubrication. In particular, the additive portion of FFOs is often precisely controlled to tailor the resultant formulation to a specific role. Analysis of the additive composition of both used and unused FFOs is therefore of great importance within the petroleum, automotive, and wider engineering industries.
    Methods: A simple and rapid reversed-phase high-performance liquid chromatography-tandem mass spectrometry method is reported herein for the analysis of a range of additives commonly encountered in FFO samples. Mass spectrometry was performed using an LTQ Orbitrap XL instrument using both positive- and negative-ion electrospray ionization. Tandem mass spectra were acquired in the data-dependent mode. FFO samples were analysed with minimal sample preparation, limited in this case to simple dilution steps.
    Results: The reported method permits analysis of a range of antioxidant, detergent, and antiwear chemistries from various FFO samples in under 10 min. Additionally, it is demonstrated that additive confirmation can be performed and some structural information obtained using the data-dependent tandem mass spectrometry method. Furthermore, analysis of additives and corresponding degradation products within a used FFO is reported.
    Conclusions: The results obtained using the reported methodology are of demonstrable use in numerous industries and applications, and readily return an abundance of information on the additive composition of a range of FFO samples. Anticipated applications of the methodology include but are not limited to quality control, suspected counterfeit analysis, and FFO degradation analysis.
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 58731-x
    ISSN 1097-0231 ; 0951-4198
    ISSN (online) 1097-0231
    ISSN 0951-4198
    DOI 10.1002/rcm.9682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Contextual modulation of associative learning and the role of resting state brain activity in posttraumatic stress disorder

    Wicking, Manon

    2017  

    Abstract: ... in an unrelated novel context, C). Self-reports, skin conductance responses (SCR), and functional ...

    Title translation Kontextmodulation beim Assoziationslernen und die Rolle der Ruhezustandsaktivität bei posttraumatischer Belastungsstörung
    Abstract Investigated neuronal changes in posttraumatic stress disorder (PTSD) using an activation-based and a resting-state-based approach with a particular focus on brain areas involved in abnormal activation in PTSD - amygdala, hippocampus, ventromedial prefrontal cortex (vmPFC), dorsal anterior cingulate cortex (dACC), and insula. Two studies compared PTSD patients with trauma-exposed but unaffected controls (non-PTSD) and trauma-naïve healthy controls (HC) to uncover the mechanisms mediating increased return of fear and the association of PTSD symptoms with aberrant brain activity as well as aberrant resting state connectivity. In Study 1, participants underwent a simulated ABC fear conditioning and extinction procedure using virtual reality scenes (fear acquisition, A; fear extinction through exposure therapy, B; and return of fear in an unrelated novel context, C). Self-reports, skin conductance responses (SCR), and functional magnetic resonance imaging (fMRI) were measured simultaneously. Results show elevated return of fear in PTSD patients indicated by larger differential SCR compared to non-PTSD and HC and larger differential amygdala and hippocampus activity compared to HC. Increased amygdala activation was positively correlated with numbing and vmPFC activity was positively correlated with behavioral avoidance. Moreover, PTSD patients failed to appropriately reduce subjective arousal to both safety and danger cues. In Study 2, subjects underwent a resting-state scan and functional connectivity was analyzed using an amygdala seed, independent component analysis (ICA), and correlations with symptom severity. Results of the seed-based approach show increased left-amygdala-left-insula coupling in PTSD versus nonPTSD, which positively correlated with re-experiencing intensity. Compared to HC, both trauma-experienced groups showed higher positive correlations of the left amygdala and the right putamen as well as the right insula. The ICA did not reveal any group differences, i.e. in default mode network (DMN) connectivity. It is concluded that PTSD may be characterized by aberrant activity within regions of the neurocircuitry model, which leads to deficient extinction maintenance. Furthermore, the general inability of PTSD patients to correctly identify safety signals and modulate fear responses based on this information may contribute to PTSD symptoms and cause relapse, whereas resilient subjects benefit from protective mechanisms. Findings of Study 2 are thought to indicate that altered amygdala-insula coupling and decreased amygdala-putamen coupling, but not DMN connectivity, contribute to the pathophysiology of PTSD. Hyperconnectivity between the left amygdala and the left insula differentiated patients from resilient subjects and was linked to re-experiencing intensity, which is argued to suggest that a stronger functional link between somatic sensations and emotional appraisal might lead to increased anticipation of negative events in PTSD. This could potentially explain hyperarousal and negative alterations in mood and cognition.
    Keywords Amygdala ; Brain Connectivity ; Conditioned Emotional Responses ; Default Mode Network ; Emotional Trauma ; Emotionales Trauma ; Extinction (Learning) ; Extinktion (Lernen) ; Fear ; Functional Magnetic Resonance Imaging ; Funktionelle Magnetresonanztomographie ; Furcht ; Hautwiderstand ; Hippocampus ; Hippokampus ; Inselkortex ; Insula ; Konditionierte emotionale Reaktionen ; Konnektivität (Gehirn) ; Physiological Arousal ; Physiologische Aktivierung ; Posttraumatic Stress Disorder ; Posttraumatische Belastungsstörung ; Ruhezustandsnetzwerk ; Skin Resistance ; Virtual Reality ; Virtuelle Realität
    Language English
    Size 117 pp.
    Publisher Universität, Medizinische Fakultät Mannheim
    Publishing place Heidelberg
    Document type Book ; Thesis
    Note Elektronische Publikation im Internet
    DOI 10.11588/heidok.00023323
    Database PSYNDEX

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  4. Article ; Online: Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation-mass spectrometry.

    Basham, Vincent / Hancock, Tom / McKendrick, John / Tessarolo, Nathalia / Wicking, Chrissie

    Rapid communications in mass spectrometry : RCM

    2022  Volume 36, Issue 14, Page(s) e9320

    Abstract: Rationale: Fully formulated oils (FFOs) are integral to automotive lubrication; however, detailed compositional analysis is challenging due to high levels of chemical complexity. In particular, existing mass spectrometric approaches often target ... ...

    Abstract Rationale: Fully formulated oils (FFOs) are integral to automotive lubrication; however, detailed compositional analysis is challenging due to high levels of chemical complexity. In particular, existing mass spectrometric approaches often target particular FFO components, leading to poor analytical coverage of the overall formulation, with increased overheads and analytical timescales.
    Methods: Herein we report the application of a commercially available SICRIT SC-20 dielectric barrier discharge ionisation (DBDI) source and Thermo Fisher Scientific LTQ Orbitrap XL to the analysis of an FFO. Nitrogen was used as a discharge gas for the DBDI source, and was modified using a range of commonplace solvents to tailor the experimental conditions for the analysis of various components.
    Results: The reported method allowed analysis of a range of FFO components of interest, encompassing a wide range of chemistries, in under 1 min. By modifying the discharge gas used for ionisation, experiments could be optimised for the analysis of particular FFO components across positive and negative ion modes. In particular, use of water vapour as a discharge gas modifier with positive ion mode mass spectrometry permitted concomitant analysis of antioxidants and base oil hydrocarbons. Furthermore, case studies of selected linear alkanes and alkenes profile the differences in the range of ions formed across these saturated and unsaturated aliphatic compounds, giving insight into the fate of base oil hydrocarbons in FFO analyses.
    Conclusions: A rapid method for analysis of FFO compositions has been developed and provides coverage of a range of components of interest. The results indicate that the method presented may be of utility in analysis of other FFOs or similarly challenging complex mixtures.
    MeSH term(s) Alkenes ; Hydrocarbons/analysis ; Mass Spectrometry/methods ; Oils
    Chemical Substances Alkenes ; Hydrocarbons ; Oils
    Language English
    Publishing date 2022-04-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 58731-x
    ISSN 1097-0231 ; 0951-4198
    ISSN (online) 1097-0231
    ISSN 0951-4198
    DOI 10.1002/rcm.9320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Embryos direct the traffic.

    Wicking, Carol

    Traffic (Copenhagen, Denmark)

    2010  Volume 11, Issue 10, Page(s) 1263–1264

    MeSH term(s) Animals ; Autophagy ; Body Patterning ; Caenorhabditis elegans/embryology ; Drosophila/embryology ; Signal Transduction ; Wnt Proteins/metabolism
    Chemical Substances Wnt Proteins
    Language English
    Publishing date 2010-10
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1483852-7
    ISSN 1600-0854 ; 1398-9219
    ISSN (online) 1600-0854
    ISSN 1398-9219
    DOI 10.1111/j.1600-0854.2010.01105.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Protecting the rare during a rare pandemic.

    Baynam, Gareth S / Wicking, Carol / Bhattacharya, Kaustuv / Millis, Nicole

    The Medical journal of Australia

    2020  Volume 213, Issue 2, Page(s) 94–94.e1

    MeSH term(s) Australia ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Health Personnel ; Humans ; Pandemics ; Pneumonia, Viral ; Rare Diseases ; SARS-CoV-2 ; Societies, Medical
    Keywords covid19
    Language English
    Publishing date 2020-06-22
    Publishing country Australia
    Document type Letter
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.50671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Chemometric approaches to resolving base oil mixtures.

    Ellick, Samuel / Wicking, Christianne / Hancock, Thomas / Whitmarsh, Samuel / Arthur, Christopher J / Gates, Paul J

    Rapid communications in mass spectrometry : RCM

    2021  Volume 36, Issue 1, Page(s) e9214

    Abstract: Rationale: In the lubrication industry, commercial base oils are commonly made up of blends of base oil stocks from different sources in different ratios to reduce production costs and modulate rheological properties. This practice introduces complexity ...

    Abstract Rationale: In the lubrication industry, commercial base oils are commonly made up of blends of base oil stocks from different sources in different ratios to reduce production costs and modulate rheological properties. This practice introduces complexity in lubricant design because as the chemistry of the base oil becomes more complicated, it can become harder to formulate the base oil - particularly when the ratio of the original base oil stocks is unknown.
    Methods: In this study, field ionisation mass spectrometry is used to collect chemical information on a range of base oil mixtures. The resultant data are processed within the Python workspace where molecular formulae are assigned to the components and statistical analyses are performed. A variety of regression techniques including regularised linear models and automated machine learning are evaluated on the data.
    Results: The use of an automated machine learning pipeline yields insight into effective modelling strategies that could be applied to the data obtained. The best results were obtained using polynomial feature generation combined with ridge cross-validation regression. Overall, with this methodology it is possible to resolve the ratio of group 2 and group 3 base oil within a blended mixture to an accuracy of ±5%.
    Conclusions: The strategies outlined in this study show how modern data science and chemometrics can be applied successfully to resolve the ratio of a complex mixture.
    Language English
    Publishing date 2021-10-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 58731-x
    ISSN 1097-0231 ; 0951-4198
    ISSN (online) 1097-0231
    ISSN 0951-4198
    DOI 10.1002/rcm.9214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: EMDR als psychotherapeutischer Ansatz in der Schmerztherapie : Ist „eye movement desensitization and reprocessing“ eine wirksame Therapie bei Patienten mit chronischen Schmerzen ohne posttraumatische Belastungsstörung?

    Wicking, M / Maier, C / Tesarz, J / Bernardy, K

    Schmerz (Berlin, Germany)

    2017  Volume 31, Issue 5, Page(s) 456–462

    Abstract: The efficacy of Eye Movement Desensitization and Reprocessing (EMDR) has been demonstrated for posttraumatic stress disorder. Despite promising research, it is still not clear if EMDR is a similarly effective treatment for chronic pain. Controlled trials ...

    Title translation EMDR as a psychotherapeutic approach in the treatment of chronic pain : Is Eye Movement Desensitization and Reprocessing an effective therapy for patients with chronic pain who do not suffer from posttraumatic stress disorder?
    Abstract The efficacy of Eye Movement Desensitization and Reprocessing (EMDR) has been demonstrated for posttraumatic stress disorder. Despite promising research, it is still not clear if EMDR is a similarly effective treatment for chronic pain. Controlled trials are lacking and whether specific mechanisms underlie the effects remains unknown. The treatment of chronic pain aims at a reduction of subjective pain sensations. To achieve this goal without the usage of pain medications, i. e. through psychotherapy, is desirable for many reasons (e. g. reduction of treatment costs and side effects). Whether or not EMDR is an effective intervention for all chronic pain patients (or just a specific subgroup) constitutes an important question for psychological pain research.
    MeSH term(s) Chronic Pain/psychology ; Chronic Pain/therapy ; Eye Movement Desensitization Reprocessing/methods ; Humans ; Psychotherapy/methods ; Stress Disorders, Post-Traumatic/psychology ; Stress Disorders, Post-Traumatic/therapy
    Language German
    Publishing date 2017-06-26
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 625283-7
    ISSN 1432-2129 ; 0932-433X
    ISSN (online) 1432-2129
    ISSN 0932-433X
    DOI 10.1007/s00482-017-0231-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: EMDR als psychotherapeutischer Ansatz in der Schmerztherapie : Ist „eye movement desensitization and reprocessing“ eine wirksame Therapie bei Patienten mit chronischen Schmerzen ohne posttraumatische Belastungsstörung?

    Wicking, M. / Maier, C. / Tesarz, J. / Bernardy, K.

    Der Schmerz

    2017  Volume 31, Issue 5, Page(s) 456–462

    Abstract: Die Wirksamkeit von „eye movement desensitization and reprocessing“ (EMDR) ist für die posttraumatische Belastungsstörung klar belegt. Inwieweit dies auch für den Einsatz bei chronischen Schmerzen gilt, ist trotz vielversprechender Veröffentlichungen ... ...

    Abstract Die Wirksamkeit von „eye movement desensitization and reprocessing“ (EMDR) ist für die posttraumatische Belastungsstörung klar belegt. Inwieweit dies auch für den Einsatz bei chronischen Schmerzen gilt, ist trotz vielversprechender Veröffentlichungen bisher unklar, da es an kontrollierten Studien mangelt. Auch die Frage, ob spezifische Wirkmechanismen für die Effekte verantwortlich sind, ist ungeklärt. Die Reduktion des subjektiven Schmerzempfindens ist erklärtes Ziel schmerztherapeutischer Behandlung. Dieses durch nichtmedikamentöse Verfahren, speziell auch durch psychotherapeutische Interventionen, zu erreichen, ist aus einer Reihe von Gründen (z. B. Reduktion von Kosten und unerwünschten Medikamentenwirkungen) erstrebenswert. Ob EMDR hier eine wirksame Intervention ist und bei welchen Schmerzpatienten die Methode wirkt, ist eine wichtige Fragestellung für die schmerzpsychologische Forschung.
    Keywords Eye movement desensitization and reprocessing ; EMDR ; Posttraumatische Belastungsstörung ; PTBS ; Psychotherapie ; Spezifität
    Language German
    Document type Article
    ZDB-ID 625283-7
    ISSN 1432-2129 ; 0932-433X
    ISSN (online) 1432-2129
    ISSN 0932-433X
    Database bibnet.org

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  10. Article ; Online: Role of Iron Speciation in Oxidation and Deposition at the Hexadecane-Iron Interface.

    Antonio, Emma N / Wicking, Christianne / Filip, Sorin / Ryan, Mary P / Heutz, Sandrine

    ACS applied materials & interfaces

    2020  Volume 12, Issue 16, Page(s) 19140–19152

    Abstract: Interactions between iron surfaces and hydrocarbons are the basis for a wide range of materials synthesis processes and novel applications, including sensing. However, in diesel engines these interactions can lead to deposit formation that reduces ... ...

    Abstract Interactions between iron surfaces and hydrocarbons are the basis for a wide range of materials synthesis processes and novel applications, including sensing. However, in diesel engines these interactions can lead to deposit formation that reduces performance, lowers efficiency, and increases emissions. Here, we present a global study to understand deposition at iron-hexadecane interfaces. We use a combination of spectroscopy, microscopy, and mass spectrometry to investigate surface reactions, bulk chemistry, and deposition processes. A dynamic equilibrium between the oxidation products, both at the surface and in solution, determines the deposition at the surface. Considering the solution and the surface in parallel, we find that the iron speciation affects the morphology, composition, and quantity of the deposit at the surface, as well as the oxidation of hexadecane. Fe(II) and Fe(III) both promote the decomposition of peroxides-intermediates in the oxidation of hexadecane-but through noncatalytic and catalytic mechanisms, respectively. In contrast, Fe(0) is proposed to initiate hexadecane autoxidation during its oxidation to Fe(III). We find that in all cases, the surfaces exclusively contain Fe(III) following heat treatment with hexadecane. Upon subsequent exposure at room temperature, Fe(III) species are found to promote oxidation; this finding is particularly concerning for hybrid vehicles where longer time periods are expected between engine operation. Our work provides a foundation for the development of strategies that disrupt the role of iron in the degradation of hexadecane to ultimately reduce oxidation and deposition in diesel engines.
    Language English
    Publishing date 2020-04-07
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.9b22983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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