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  1. Article ; Online: Teaching Trans-Centric Curricular Content Using Modified Jigsaw.

    Zheng, Cynthia / D'Costa, Zoee / Zachow, Rob J / Lebeau, Robert / Bachmann, Gloria A

    MedEdPORTAL : the journal of teaching and learning resources

    2022  Volume 18, Page(s) 11257

    Abstract: Introduction: Transgender (trans) individuals have unique medical needs and difficulty accessing quality health care, exacerbated by inadequate provider knowledge. Incorporation of trans health care into medical school curricula has increased recently ... ...

    Abstract Introduction: Transgender (trans) individuals have unique medical needs and difficulty accessing quality health care, exacerbated by inadequate provider knowledge. Incorporation of trans health care into medical school curricula has increased recently to address this gap. Jigsaw activities emphasize positive interdependence through structured cooperative learning, resulting in increased interest and self-confidence. We implemented a voluntary 2-hour modified jigsaw exercise on trans health care with changes designed to optimize the structure for medical students.
    Methods: The session was implemented both in person and virtually over 2 years with preclerkship medical students at the end of their endocrine/reproduction physiology course. The session featured a knowledge test with answer discussion followed by a clinical correlation-either a case discussion or video discussion. A pre- and posttest design compared students' knowledge, attitudes, and beliefs.
    Results: Eighty-nine students participated. Their initial attitudes and beliefs regarding trans health care were highly positive and remained elevated. Participants showed increases in knowledge and self-confidence discussing gender identity and clinical care postsession. All expressed interest in further training and felt the session enhanced their understanding of trans health and reproductive physiology. On 1-year follow-up, students showed decreased knowledge and self-confidence in discussing trans health; however, scores remained higher than presession. Student surveys suggested formal integration of more trans health education into the curriculum.
    Discussion: Medical students increased their knowledge and self-confidence regarding trans medicine and felt the modified jigsaw exercise was an effective teaching method. The results suggest that ongoing education is an important tool in optimizing trans health care.
    MeSH term(s) Curriculum ; Female ; Gender Identity ; Humans ; Learning ; Male ; Schools, Medical ; Students, Medical
    Language English
    Publishing date 2022-05-24
    Publishing country United States
    Document type Journal Article
    ISSN 2374-8265
    ISSN (online) 2374-8265
    DOI 10.15766/mep_2374-8265.11257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Applied and Integrative Endocrinology Case

    Rob Zachow

    MedEdPORTAL, Vol

    A 31-Year-Old Woman With Shortness of Breath, Chest Pain, Nausea, and Dizziness

    2012  Volume 8

    Abstract: Abstract This case describes a 31-year-old woman with ovarian hyperstimulation syndrome (OHSS). The pathogenesis of her OHSS results in the development of a constellation of cardiopulmonary and body fluid imbalances. This case can be used in any small ... ...

    Abstract Abstract This case describes a 31-year-old woman with ovarian hyperstimulation syndrome (OHSS). The pathogenesis of her OHSS results in the development of a constellation of cardiopulmonary and body fluid imbalances. This case can be used in any small and/or large group setting; the suggested discussion topics can be modified for use within physiology and pathophysiology curriculum throughout undergraduate medical school. When combined with the reproductive endocrine aspects of the case, this exercise provides a rich platform for the discussion of female reproductive endocrinology, as well as the normal and compensatory function of integrated physiologic systems. I have used this exercise in both the large and small group setting. On a scale of 1–5 (1 indicating strongly disagree, 5 indicating strongly agree) the students were asked to evaluate the following as part of the end-of-course evaluation (2011): The applied medical sciences case, “A 31-year-old woman with shortness of breath, chest pain, nausea, and dizziness” was an effective learning exercise. Responses: 4.5 (0.4) The applied medical sciences case, “A 31-year-old woman with shortness of breath, chest pain, nausea, and dizziness” was an effective use of curricular time. Responses 4.1 (0.6) Written comments linked to this part of the evaluation were overwhelmingly positive: I most recently (March, 2012) used this case in the large group setting as the foundation for a review of the Renal-Endocrine course at RWJMS; data from this session are pending.
    Keywords Metabolic Acidosis ; Tachycardia ; Ovary ; Gonadotropins ; Angiotensins ; Ovulation ; Medicine (General) ; R5-920 ; Education ; L
    Subject code 796
    Language English
    Publishing date 2012-03-01T00:00:00Z
    Publisher Association of American Medical Colleges
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Teaching Trans-Centric Curricular Content Using Modified Jigsaw

    Cynthia Zheng / Zoee D'Costa / Rob J. Zachow / Robert Lebeau / Gloria A. Bachmann

    MedEdPORTAL, Vol

    2022  Volume 18

    Abstract: Introduction Transgender (trans) individuals have unique medical needs and difficulty accessing quality health care, exacerbated by inadequate provider knowledge. Incorporation of trans health care into medical school curricula has increased recently to ... ...

    Abstract Introduction Transgender (trans) individuals have unique medical needs and difficulty accessing quality health care, exacerbated by inadequate provider knowledge. Incorporation of trans health care into medical school curricula has increased recently to address this gap. Jigsaw activities emphasize positive interdependence through structured cooperative learning, resulting in increased interest and self-confidence. We implemented a voluntary 2-hour modified jigsaw exercise on trans health care with changes designed to optimize the structure for medical students. Methods The session was implemented both in person and virtually over 2 years with preclerkship medical students at the end of their endocrine/reproduction physiology course. The session featured a knowledge test with answer discussion followed by a clinical correlation—either a case discussion or video discussion. A pre- and posttest design compared students’ knowledge, attitudes, and beliefs. Results Eighty-nine students participated. Their initial attitudes and beliefs regarding trans health care were highly positive and remained elevated. Participants showed increases in knowledge and self-confidence discussing gender identity and clinical care postsession. All expressed interest in further training and felt the session enhanced their understanding of trans health and reproductive physiology. On 1-year follow-up, students showed decreased knowledge and self-confidence in discussing trans health; however, scores remained higher than presession. Student surveys suggested formal integration of more trans health education into the curriculum. Discussion Medical students increased their knowledge and self-confidence regarding trans medicine and felt the modified jigsaw exercise was an effective teaching method. The results suggest that ongoing education is an important tool in optimizing trans health care.
    Keywords Jigsaw ; Transgender ; Discussion ; Small Group (≤12) ; Endocrinology ; Gender Identity ; Medicine (General) ; R5-920 ; Education ; L
    Subject code 796
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Association of American Medical Colleges
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Four Web-Based Interactive Endocrine Case Studies for Use in Undergraduate Medical Education.

    Zachow, Rob / Schneider, Stephen / Lebeau, Robert / Galt, James

    MedEdPORTAL : the journal of teaching and learning resources

    2017  Volume 13, Page(s) 10579

    Abstract: Introduction: This resource is a collection of four case-based exercises intended to provide medical students with structured and focused opportunities to link basic science with clinical application. The cases are designed to help students self- ... ...

    Abstract Introduction: This resource is a collection of four case-based exercises intended to provide medical students with structured and focused opportunities to link basic science with clinical application. The cases are designed to help students self-evaluate their knowledge and develop a robust and well- integrated understanding of endocrine physiology and pathophysiology in the context of a representative range of endocrine disorders involving adrenal cortical, thyroid, and reproductive function. Although these cases were designed for, and used by, first-year students, they are also suitable for more advanced students.
    Methods: Each case opens with a brief vignette containing a patient presentation and a history of present illness. The student first formulates a differential diagnosis and then sequentially narrows the differential by selecting from lists of diagnostic tests; correct answers with feedback are provided at each step. A diagnosis is ultimately required, and the student may be prompted to propose a treatment plan.
    Results: End-of-course survey results from 128 first-year medical students suggest that the use of these interactive case studies was considered to be a worthwhile use of study time, and that knowledge gained in the correlate endocrine course was required to work through the cases. Students indicated that the levels of case and task complexity, along with feedback, were appropriate and helpful.
    Discussion: These cases provide a resource for meeting the need for clinically relevant scenarios in the preclerkship years.
    Language English
    Publishing date 2017-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 2374-8265
    ISSN (online) 2374-8265
    DOI 10.15766/mep_2374-8265.10579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Four Web-Based Interactive Endocrine Case Studies for Use in Undergraduate Medical Education

    Rob Zachow / Stephen Schneider / Robert Lebeau / James Galt

    MedEdPORTAL, Vol

    2017  Volume 13

    Abstract: Introduction This resource is a collection of four case-based exercises intended to provide medical students with structured and focused opportunities to link basic science with clinical application. The cases are designed to help students self-evaluate ... ...

    Abstract Introduction This resource is a collection of four case-based exercises intended to provide medical students with structured and focused opportunities to link basic science with clinical application. The cases are designed to help students self-evaluate their knowledge and develop a robust and well- integrated understanding of endocrine physiology and pathophysiology in the context of a representative range of endocrine disorders involving adrenal cortical, thyroid, and reproductive function. Although these cases were designed for, and used by, first-year students, they are also suitable for more advanced students. Methods Each case opens with a brief vignette containing a patient presentation and a history of present illness. The student first formulates a differential diagnosis and then sequentially narrows the differential by selecting from lists of diagnostic tests; correct answers with feedback are provided at each step. A diagnosis is ultimately required, and the student may be prompted to propose a treatment plan. Results End-of-course survey results from 128 first-year medical students suggest that the use of these interactive case studies was considered to be a worthwhile use of study time, and that knowledge gained in the correlate endocrine course was required to work through the cases. Students indicated that the levels of case and task complexity, along with feedback, were appropriate and helpful. Discussion These cases provide a resource for meeting the need for clinically relevant scenarios in the preclerkship years.
    Keywords Physiology ; Pathophysiology ; Case-Based Learning ; Hypogonadism ; Endocrinology ; Cushing's Syndrome ; Medicine (General) ; R5-920 ; Education ; L
    Subject code 420
    Language English
    Publishing date 2017-05-01T00:00:00Z
    Publisher Association of American Medical Colleges
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Applied Medical Sciences in Endocrinology

    Rob Zachow / Stephen Schneider

    MedEdPORTAL, Vol

    A 23-Year-Old Woman With Amenorrhea

    2013  Volume 9

    Abstract: Abstract Introduction The intent of this resource is to use a detailed, authentic clinical presentation to extend and reinforce students' comprehension and application of medical science content; topics in female reproductive endocrinology are specific ... ...

    Abstract Abstract Introduction The intent of this resource is to use a detailed, authentic clinical presentation to extend and reinforce students' comprehension and application of medical science content; topics in female reproductive endocrinology are specific to this exercise. The case enables learners to integrate aspects of physiology and pathophysiology with clinical medicine (e.g., diagnosis). Following this approach, the learning process is engaged by using large-group discussion based on a clinical scenario. This method has the potential to addresses some important areas in early medical training: introduction to the level of knowledge necessary to provide quality patient care, the importance and significance of a firm understanding of basic science content in providing accurate diagnosis (and ultimately treatment), and better preparation of medical students for the integrated thinking that enables success on the United States Medical Licensing Examinations. Methods This case-based exercise explores the etiology of secondary amenorrhea in a 23-year-old woman. This athletic woman has been using anabolic androgenic steroids for performance enhancement, which explains her amenorrhea. However, this diagnosis is not immediately obvious given her history, physical, and blood lab results. Certain paradoxical findings are meant to help students realize that an endogenous pathology cannot fully account for her signs and symptoms. The exercise begins with the case presentation; discussion topics and questions are inserted throughout for the purpose of having the students describe the essential elements of normal female reproductive endocrinology, develop a differential diagnosis, and narrow the differential with their knowledge of endocrinology, using the data provided. An online three-item self-assessment is provided following the session. Results On an anonymous, web-based, end-of-course survey, students were asked to rate the following statement: “Applied Medical Sciences, Female Reproductive Endocrinology: Overall, in ...
    Keywords Menstrual Cycle ; Amenorrhea ; Anabolic Androgenic Steroid ; Hypogonadism ; Testosterone ; Progesterone ; Medicine (General) ; R5-920 ; Education ; L
    Subject code 796
    Language English
    Publishing date 2013-04-01T00:00:00Z
    Publisher Association of American Medical Colleges
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Interprofessional Education Small Group

    Rob Zachow / David Riley / Joe Schwenkler

    MedEdPORTAL, Vol

    A 25-Year-Old-Man with Dyspnea, Productive Cough, and Chest Tightness

    2014  Volume 10

    Abstract: Abstract Introduction This simulation case was developed for use as part of the Rutgers-Robert Wood Johnson Medical School interprofessional education initiative. It was designed to foster the health care team approach among first-year medical, physician ...

    Abstract Abstract Introduction This simulation case was developed for use as part of the Rutgers-Robert Wood Johnson Medical School interprofessional education initiative. It was designed to foster the health care team approach among first-year medical, physician assistant, and pharmacy students. The case describes a man with mild intermittent asthma who presents to the emergency department due to an exacerbation. Methods Six discussion topics were designed for use in a small-group teaching environment. These explore various aspects of asthma, including its pathophysiology, effect on normal pulmonary physiology, medical management (i.e., pharmacology), and follow-up care. A postsession survey was disseminated to all students. Results When asked to rate the statement “Overall in terms of reinforcement of concepts, and integration of course material, and conveying a health care team approach to problem solving, this small-group session met my learning needs” on a 5-point Likert scale (strongly disagree = 1, strongly agree = 5), students responses were: 3.8% (n = 4) strongly disagree, 17.1% disagree (n = 18), 24.8% neutral (n = 26), 44.8% agree (n = 47), 9.5% strongly agree (n = 10). The Likert average for all responses (N = 105) was 3.4. Discussion Student comments indicate that this modality served both the interprofessional education and didactic objectives of this small group. In addition, this session promoted professional interactions, which otherwise may not have occurred, between the faculty within the representative schools.
    Keywords Physiology ; Lung ; Asthma ; Small Group Teaching ; Pulmonary ; Pathophysiology ; Medicine (General) ; R5-920 ; Education ; L
    Subject code 370
    Language English
    Publishing date 2014-07-01T00:00:00Z
    Publisher Association of American Medical Colleges
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Developmental exposure to environmental endocrine disruptors: consequences within the ovary and on female reproductive function.

    Uzumcu, Mehmet / Zachow, Rob

    Reproductive toxicology (Elmsford, N.Y.)

    2007  Volume 23, Issue 3, Page(s) 337–352

    Abstract: Female reproductive function depends upon the exquisite control of ovarian steroidogenesis that enables folliculogenesis, ovulation, and pregnancy. These mechanisms are set during fetal and/or neonatal development and undergo phases of differentiation ... ...

    Abstract Female reproductive function depends upon the exquisite control of ovarian steroidogenesis that enables folliculogenesis, ovulation, and pregnancy. These mechanisms are set during fetal and/or neonatal development and undergo phases of differentiation throughout pre- and post-pubescent life. Ovarian development and function are collectively regulated by a host of endogenous growth factors, cytokines, gonadotropins, and steroid hormones as well as exogenous factors such as nutrients and environmental agents. Endocrine disruptors represent one class of environmental agent that can impact female fertility by altering ovarian development and function, purportedly through estrogenic, anti-estrogenic, and/or anti-androgenic effects. This review discusses ovarian development and function and how these processes are affected by some of the known estrogenic and anti-androgenic endocrine disruptors. Recent information suggests not only that exposure to endocrine disruptors during the developmental period causes reproductive abnormalities in adult life but also that these abnormalities are transgenerational. This latter finding adds another level of importance for identifying and understanding the mechanisms of action of these agents.
    MeSH term(s) Animals ; Embryonic Development/drug effects ; Endocrine Disruptors/chemistry ; Endocrine Disruptors/poisoning ; Environmental Pollutants/chemistry ; Environmental Pollutants/poisoning ; Female ; Humans ; Ovary/drug effects ; Ovary/embryology ; Pregnancy ; Prenatal Exposure Delayed Effects ; Reproduction/drug effects ; Reproduction/physiology
    Chemical Substances Endocrine Disruptors ; Environmental Pollutants
    Language English
    Publishing date 2007-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 639342-1
    ISSN 1873-1708 ; 0890-6238
    ISSN (online) 1873-1708
    ISSN 0890-6238
    DOI 10.1016/j.reprotox.2006.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The hepatocyte growth factor system as a regulator of female and male gonadal function.

    Zachow, Rob / Uzumcu, Mehmet

    The Journal of endocrinology

    2007  Volume 195, Issue 3, Page(s) 359–371

    Abstract: The hepatocyte growth factor (HGF) system comprises HGF, its receptor (the c-met tyrosine kinase), HGF activator (HGFA) protein, and HGFA inhibitor (HAI). The components of the HGF system have been identified in a plethora of tissues to include the ovary ...

    Abstract The hepatocyte growth factor (HGF) system comprises HGF, its receptor (the c-met tyrosine kinase), HGF activator (HGFA) protein, and HGFA inhibitor (HAI). The components of the HGF system have been identified in a plethora of tissues to include the ovary and testis. In its traditional context, the HGF system works via paracrine- and autocrine-mediated feedback in which HGF (of mesenchymal origin) binds and activates c-met (within epithelial cells); target cells then respond to HGF via any number of morphogenic and functional changes. The concomitant presence of HGFA and HAI suggests that HGF bioactivity can be locally modulated. A number of studies have collectively shown that the mammalian ovary and testis contain HGF, c-met, and HGFA; very little is currently known regarding HAI within the gonad. Within the ovary, HGF controls numerous key functions which collectively regulate the growth and differentiation of ovarian follicles; these include cell growth, steroidogenesis, and apoptosis within theca cells and/or granulosa cells. Comparatively, less is known about the function of HGF within the testicular Leydig and Sertoli cells, but evidence is emerging that HGF may regulate somatic cell function, including Leydig cell steroidogenesis. Changes in the cellular origin of HGF and c-met during fetal and postnatal testicular development suggest that HGF, in collaboration with other growth factors, may regulate important aspects of testicular cell morphogenesis and differentiation which enable male sexual viability. Likewise, experimental evidence showing that HGF can modulate many vital processes which enable ovarian follicle growth, differentiation, and function indicate the importance of HGF in female reproduction. This review presents what is currently known regarding the expression of the HGF system and its function within the ovary and testis.
    MeSH term(s) Animals ; Apoptosis/physiology ; Cell Division/physiology ; Female ; Gonadal Steroid Hormones/biosynthesis ; Granulosa Cells/cytology ; Granulosa Cells/physiology ; Hepatocyte Growth Factor/physiology ; Humans ; Leydig Cells/metabolism ; Male ; Ovarian Follicle/cytology ; Ovarian Follicle/growth & development ; Ovary/cytology ; Ovary/metabolism ; Ovary/physiology ; Testis/physiology ; Theca Cells/cytology ; Theca Cells/physiology
    Chemical Substances Gonadal Steroid Hormones ; Hepatocyte Growth Factor (67256-21-7)
    Language English
    Publishing date 2007-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3028-4
    ISSN 1479-6805 ; 0022-0795
    ISSN (online) 1479-6805
    ISSN 0022-0795
    DOI 10.1677/JOE-07-0466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Introduction to Electrocardiography Diagnostic Skills

    Rob Zachow / James Coromilas / Carol Sadley

    MedEdPORTAL, Vol

    2012  Volume 8

    Abstract: Abstract This session is designed to introduce first-year medical students to the basic skills required to interpret electrocardiography (ECG). Using the small-group modality, students are provided with a fundamental knowledge of how to analyze eight ... ...

    Abstract Abstract This session is designed to introduce first-year medical students to the basic skills required to interpret electrocardiography (ECG). Using the small-group modality, students are provided with a fundamental knowledge of how to analyze eight illustrative normal and pathologic ECG strips in order to determine the rate, dominant rhythm, electrical axis, intervals, and wave forms. This diagnostic skills session has been part of our M1 Cardiopulmonary course for 2 years. In both years presented, the students have ranked this as one of the best small-group sessions of the entire year. They consistently comment that the time was well-spent. Many of our present M2 students (the first recipients of this exercise) have stated that having a good basic working knowledge of electrocardiography helped prepare them for M2 cardiopulmonary.
    Keywords Atrial Fibrillation ; Tachycardia ; Bradycardia ; Cardiac Arrhythmias ; Tachyarrhythmia ; Ischemia ; Medicine (General) ; R5-920 ; Education ; L
    Language English
    Publishing date 2012-04-01T00:00:00Z
    Publisher Association of American Medical Colleges
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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