Article: Cariprazine in Three Acute Patients with Schizophrenia: A Real-World Experience.
Neuropsychiatric disease and treatment
2021 Volume 17, Page(s) 291–296
Abstract: There are still some unmet needs in the treatment of schizophrenia like the persistence of negative symptoms. Cariprazine is a new-generation antipsychotic with partial agonism of the dopamine receptors, distinct from other antipsychotics by its 10 times ...
Abstract | There are still some unmet needs in the treatment of schizophrenia like the persistence of negative symptoms. Cariprazine is a new-generation antipsychotic with partial agonism of the dopamine receptors, distinct from other antipsychotics by its 10 times greater affinity for D3 receptors. This mechanism of action could be especially favorable on patients with predominant negative symptoms. This report is showing three clinical cases of acute schizophrenia exacerbation that required hospitalization and were successfully treated with cariprazine. All of them had predominant positive symptoms and two of them had substance use. Efficacy of cariprazine was also crucial on negative and cognitive symptoms with excellent tolerability. |
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Language | English |
Publishing date | 2021-02-03 |
Publishing country | New Zealand |
Document type | Case Reports |
ZDB-ID | 2186503-6 |
ISSN | 1178-2021 ; 1176-6328 |
ISSN (online) | 1178-2021 |
ISSN | 1176-6328 |
DOI | 10.2147/NDT.S298005 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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