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  1. Article ; Online: Reconstructing the first COVID-19 pandemic wave with minimal data

    Chen, Siyu / White, Lisa J

    medRxiv

    Abstract: Early pandemic diagnostic tool is key important to provide timely pieces of evidence for public health decision making in the early pandemic where data was sparse. In this paper, we demonstrate how a published model can be used to reconstruct the first ... ...

    Abstract Early pandemic diagnostic tool is key important to provide timely pieces of evidence for public health decision making in the early pandemic where data was sparse. In this paper, we demonstrate how a published model can be used to reconstruct the first COVID-19 pandemic wave with minimal dataset.
    Keywords covid19
    Language English
    Publishing date 2023-03-20
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2023.03.17.23287140
    Database COVID19

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  2. Article ; Online: Can technology change the status quo for pressure injury prevention?

    Gould, Lisa J / White-Chu, Elizabeth

    The British journal of dermatology

    2022  Volume 187, Issue 4, Page(s) 456

    MeSH term(s) Humans ; Decision Making ; Technology ; Pressure Ulcer
    Language English
    Publishing date 2022-07-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.21714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Disparity in pseudohyphal morphogenic switching response to the quorum sensing molecule 2-phenylethanol in commercial brewing strains of

    Britton, Scott J / Rogers, Lisa J / White, Jane S / Neven, Hedwig / Maskell, Dawn L

    FEMS microbes

    2023  Volume 4, Page(s) xtad002

    Abstract: Saccharomyces ... ...

    Abstract Saccharomyces cerevisiae
    Language English
    Publishing date 2023-01-09
    Publishing country England
    Document type Journal Article
    ISSN 2633-6685
    ISSN (online) 2633-6685
    DOI 10.1093/femsmc/xtad002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Supramolecular Self-Associating Amphiphiles Inhibit Biofilm Formation by the Critical Pathogens,

    Steyn, Hendrik J F / White, Lisa J / Hilton, Kira L F / Hiscock, Jennifer R / Pohl, Carolina H

    ACS omega

    2023  Volume 9, Issue 1, Page(s) 1770–1785

    Abstract: In 2019, 4.95 million deaths were directly attributed to antimicrobial-resistant bacterial infections globally. In addition, the mortality associated with fungal infections is estimated at 1.7 million annually, with many of these deaths attributed to ... ...

    Abstract In 2019, 4.95 million deaths were directly attributed to antimicrobial-resistant bacterial infections globally. In addition, the mortality associated with fungal infections is estimated at 1.7 million annually, with many of these deaths attributed to species that are no longer susceptible to traditional therapeutic regimes. Herein, we demonstrate the use of a novel class of supramolecular self-associating amphiphilic (SSA) salts as antimicrobial agents against the critical pathogens
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c08425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Becoming a teacher : Research on the work-integrated learning of student teachers

    Mentz, Elsa / De Beer, Josef / Petersen, Neal / Van Vuuren, Herman J / Botha, Carolina / Botha, Lettie / Bunt, Byron / Conley, Lloyd / Dieker, Lisa / Gravett, Sarah / Jagals, Divan / Marais, Elma / Nel, Carisma / Oosthuizen, Izak Johannes / Petersen, Nadine / Ramsaroop, Sarita / Rens, Julialet / Reyneke, Maryna / Sebotsa, Tswakae /
    Speight Vaughn, Melissa / van der Walt, Marthie / White, Lounell

    2020  

    Keywords Education ; Pre-service teacher education ; Work-integrated learning ; Theory-practice divide ; School experience ; Self-directed learning ; Mixed-methods research ; Student teacher
    Size 1 electronic resource (470 pages)
    Publisher AOSIS
    Publishing place Durbanville
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021051304
    ISBN 9781928523352 ; 1928523358
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Rahnella Aquatilis Endophthalmitis after Intravitreal Injection in an Immunocompetent Patient.

    Williams, Parker J / Xue, Gilbert / Ross, Bing X / White, Erika / Shammas, Lisa / Yoganathan, Pradeepa / Chapman, Christopher / Lin, Xihui

    Retinal cases & brief reports

    2024  

    Abstract: Purpose: To present a novel case of exogenous Rahnella aquatilis endophthalmitis following an intravitreal injection.: Methods: Case report.: Results: A 74-year-old male presented with acute progressive vision loss and pain in the left eye, 5 days ...

    Abstract Purpose: To present a novel case of exogenous Rahnella aquatilis endophthalmitis following an intravitreal injection.
    Methods: Case report.
    Results: A 74-year-old male presented with acute progressive vision loss and pain in the left eye, 5 days after an intravitreal injection for diabetic macular edema. The patient was diagnosed with exogenous endophthalmitis and empirically treated with intravitreal injections of vancomycin and ceftazidime as well as topical and oral ciprofloxacin. In follow up two days later, the patient was treated with preoperative povidone-iodine followed by prompt vitrectomy with additional vancomycin and ceftazidime due to pharmacy sterile hood issues that delayed antibiotic availability. Microbiological cultures and two mass spectrometry identification tests confirmed the diagnosis of exogenous Rahnella aquatilis endophthalmitis. Despite the presence of scattered retinal hemorrhagic infarcts involving the macula and subsequent full-thickness atrophic macular holes seen in follow up, the patient achieved a favorable anatomical and functional outcome of BCVA 20/80 at 1 year of follow-up.
    Conclusion: This case highlights the occurrence of exogenous Rahnella aquatilis endophthalmitis following an intravitreal injection for diabetic macular edema. Prompt diagnosis and treatment produced a favorable outcome relative to other typical Gram-negative Enterobacteriaceae organisms.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Strengths and opportunities in research into extracellular matrix ageing: A consultation with the ECMage research community.

    Dalby, Matthew J / Pekovic-Vaughan, Vanja / Shanley, Daryl P / Swift, Joe / White, Lisa J / Canty-Laird, Elizabeth G

    BioEssays : news and reviews in molecular, cellular and developmental biology

    2024  Volume 46, Issue 5, Page(s) e2300223

    Abstract: Ageing causes progressive decline in metabolic, behavioural, and physiological functions, leading to a reduced health span. The extracellular matrix (ECM) is the three-dimensional network of macromolecules that provides our tissues with structure and ... ...

    Abstract Ageing causes progressive decline in metabolic, behavioural, and physiological functions, leading to a reduced health span. The extracellular matrix (ECM) is the three-dimensional network of macromolecules that provides our tissues with structure and biomechanical resilience. Imbalance between damage and repair/regeneration causes the ECM to undergo structural deterioration with age, contributing to age-associated pathology. The ECM 'Ageing Across the Life Course' interdisciplinary research network (ECMage) was established to bring together researchers in the United Kingdom, and internationally, working on the emerging field of ECM ageing. Here we report on a consultation at a joint meeting of ECMage and the Medical Research Council / Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing, held in January 2023, in which delegates analysed the key questions and research opportunities in the field of ECM ageing. We examine fundamental biological questions, enabling technologies, systems of study and emerging in vitro and in silico models, alongside consideration of the broader challenges facing the field.
    MeSH term(s) Extracellular Matrix/metabolism ; Humans ; Aging ; Animals ; United Kingdom
    Language English
    Publishing date 2024-03-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 50140-2
    ISSN 1521-1878 ; 0265-9247
    ISSN (online) 1521-1878
    ISSN 0265-9247
    DOI 10.1002/bies.202300223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2024: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Promoting a more diverse and inclusive research workforce through the research scholars program.

    Schoenberg, Nancy E / Robinson, Jimmy / McGladrey, Margaret / Cassis, Lisa A / Conwell, Darwin / Pearson, Kevin J / Tannock, Lisa R / Wilcock, Donna / White, Stephanie

    BMC medical education

    2024  Volume 24, Issue 1, Page(s) 98

    Abstract: Background: Novel and comprehensive approaches are needed to address shortcomings in the diversity and inclusiveness of the scientific workforce. In response to this need and informed by multiple programs and data sources, we created the Research ... ...

    Abstract Background: Novel and comprehensive approaches are needed to address shortcomings in the diversity and inclusiveness of the scientific workforce. In response to this need and informed by multiple programs and data sources, we created the Research Scholars Program (RSP). The RSP is a yearlong program for early-career faculty with an overall objective to overcome barriers to the academic success, retention, progression, and promotion of groups underrepresented in biomedical and behavioral research. The goal of the RSP is to increase research confidence and productivity, build a supportive research community, and reduce isolation by providing personal and group research enrichment to junior faculty through professional development, mentorship, and networking.
    Methods: We adapted evidence-based approaches for our institutional context and vetted the RSP across our campus. The resulting RSP consists of three main elements: (1) five levels of Mosaic Mentorship; (2) group and tailored professional development programming; and (3) scientific and social networking. To determine the potential of the RSP to improve research confidence critical to success, we used a modified shortened version of the Clinical Research Appraisal Inventory (CRAI-12) to assess participants' confidence in performing a variety of research tasks before and after program participation. We collected information about retention, promotion, and grants submitted and awarded. Additionally, we conducted semi-structured exit interviews with each scholar after program participation to identify programmatic strengths and areas for improvement. Data for Cohorts 1 and 2 (N = 12) were analyzed.
    Results: Our assessment finds, with one exception, increasing confidence in participants' research skills across all items, ranging from 0.4 (4.7%) to 2.6 (40.6%). In their exit interviews, the Research Scholars (RS) described their improved productivity and increased sense of belonging and support from others. Research Scholars noted numerous components of the RSP as strengths, including the Mosaic Mentorship model, professional development programming, and opportunities for both informal and formal interactions. Respondents identified time pressure, a lack of feedback, and unclear expectations of the various mentorship roles as areas in which the program can improve.
    Conclusion: Preliminary findings indicate that the RSP is successful in building the research confidence of underrepresented and disadvantaged early-career faculty. While this report focuses on the development and protocol of the RSP, additional cohorts and data will provide the evidence base to support dissemination as a national model of research professional development. Such programming is critical to ensure sustainable support structures, institutional networks, infrastructure, and resources that will improve discovery and equity through inclusive excellence.
    MeSH term(s) Humans ; Mentors ; Faculty ; Mental Processes ; Workforce
    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-024-05075-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Investigating midwives and nurses reporting of 'infant feeding at hospital discharge': an online survey across NSW Australia.

    Henry, Lynne / Burns, Elaine / Jones, Rachel / White, Lisa / Simmons, Michelle / Kirby, Adrienne / Melov, Sarah J

    International breastfeeding journal

    2024  Volume 19, Issue 1, Page(s) 29

    Abstract: Background: The collection of data on 'infant feeding at hospital discharge' is used to monitor breastfeeding outcomes, health service benchmarking, and research. While some Australian states have clear definitions of this data collection point, there ... ...

    Abstract Background: The collection of data on 'infant feeding at hospital discharge' is used to monitor breastfeeding outcomes, health service benchmarking, and research. While some Australian states have clear definitions of this data collection point, there is no operational definition of 'infant feeding at hospital discharge' in the Australian state of New South Wales. Little is known about how midwives interpret the term 'infant feeding at hospital discharge', in particular, the timeframe used to calculate these important indicators. The purpose of this study was to explore midwives' and nurses' practices of reporting 'infant feeding at hospital discharge' in the Australian state of New South Wales.
    Methods: An online survey was distributed across public and private maternity hospitals in New South Wales, Australia. The survey asked midwives and nurses their practice of reporting 'infant feeding at discharge' from categories offered by the state Mothers and Babies report of either "full breastfeeding", "any breastfeeding", and "infant formula only". The Qualtrics survey was available from December 2021 to May 2022.
    Results: There were 319 completed surveys for analysis and all 15 NSW Health Districts were represented. Some participants reported using the timeframe 'since birth' as a reference (39%), however, the majority (54%, n = 173) referenced one of the feeding timeframes within the previous 24 h. Most midwives and nurses (83%, n = 265) recommended 24 h before discharge as the most relevant reference timeframe, and 65% (n = 207) were in favour of recording data on 'exclusive breastfeeding' since birth.
    Conclusion: This study identified multiple practice inconsistencies within New South Wales reporting of 'infant feeding at hospital discharge'. This has ramifications for key health statistics, state reporting, and national benchmarking. While the Baby Friendly Hospital Initiative accreditation requires hospitals to demonstrate and continuously monitor at least a 75% exclusive breastfeeding rate on discharge, only 11 New South Wales facilities have achieved this accreditation. We recommend introducing an option to collect 'exclusive breastfeeding' on discharge' which is in line with participant recommendations and the Baby Friendly Hospital accreditation. Other important considerations are the updated World Health Organization indicators such as, "Ever breastfed"; "Early initiation of breastfeeding" (first hour); "Exclusively breastfed for the first two days after birth".
    MeSH term(s) Humans ; New South Wales ; Breast Feeding ; Female ; Patient Discharge ; Surveys and Questionnaires ; Infant, Newborn ; Adult ; Nurses ; Midwifery ; Infant ; Male ; Pregnancy
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2227239-2
    ISSN 1746-4358 ; 1746-4358
    ISSN (online) 1746-4358
    ISSN 1746-4358
    DOI 10.1186/s13006-024-00637-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: No Evidence That Analgesic Use after COVID-19 Vaccination Negatively Impacts Antibody Responses.

    Lafleur, Bonnie J / White, Lisa / Dake, Michael D / Nikolich, Janko Z / Sprissler, Ryan / Bhattacharya, Deepta

    ImmunoHorizons

    2023  Volume 7, Issue 12, Page(s) 834–841

    Abstract: Uptake of mRNA vaccines, especially booster immunizations, against COVID-19 has been lower than hoped, perhaps in part due to their reactogenicity. Analgesics might alleviate symptoms associated with vaccination, but they might also impact immune ... ...

    Abstract Uptake of mRNA vaccines, especially booster immunizations, against COVID-19 has been lower than hoped, perhaps in part due to their reactogenicity. Analgesics might alleviate symptoms associated with vaccination, but they might also impact immune responses. We semiquantitatively measured Ab responses following COVID-19 vaccination in 2354 human participants surveyed about analgesic use after vaccination. Participants who used nonsteroidal anti-inflammatory drugs or acetaminophen after vaccination showed elevated Ab levels against the receptor-binding domain of Spike protein relative to those who did not use analgesics. This pattern was observed for both mRNA-1273 and BNT162b2 and across age groups. Participants who used analgesics more frequently reported fatigue, muscle aches, and headaches than did those who did not use painkillers. Among participants who reported these symptoms, we observed no statistically significant differences in Ab levels irrespective of analgesic use. These data suggest that elevated Ab levels are associated with symptoms and inflammatory processes rather than painkiller use per se. Taken together, we find no evidence that analgesic use reduces Ab responses after COVID-19 vaccination. Recommendation of their use to alleviate symptoms might improve uptake of booster immunizations.
    MeSH term(s) Humans ; Analgesics/therapeutic use ; Antibody Formation ; BNT162 Vaccine ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Vaccination
    Chemical Substances Analgesics ; BNT162 Vaccine ; COVID-19 Vaccines
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ISSN 2573-7732
    ISSN (online) 2573-7732
    DOI 10.4049/immunohorizons.2300090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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