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Article: Building Evidence for Principles to Guide the Development of Products for Adults with Intellectual and Developmental Disabilities and Extreme Low Literacy-A Product Development Tool.

Squiers, Linda / Lynch, Molly M / Holt, Sidney L / Rivell, Aileen / Walker, Kathleen / Robison, Stacy / Mitchell, Elizabeth W / Flores, Alina L

Healthcare (Basel, Switzerland)

2023 Volume 11, Issue 12

Abstract: This article presented a new product development tool for adults with intellectual and developmental disabilities (IDD) developed by the Centers for Disease Control and Prevention (CDC). People with IDD who also have extreme low literacy (ELL) have ... ...

Abstract	This article presented a new product development tool for adults with intellectual and developmental disabilities (IDD) developed by the Centers for Disease Control and Prevention (CDC). People with IDD who also have extreme low literacy (ELL) have unique communication needs; public health communicators often face challenges developing effective communication materials for this audience. To support CDC communication specialists with the development of communication products for adults with IDD/ELL, CDC, with its partners RTI International and CommunicateHealth, created a product development tool for this audience through literature review, expert input, and interviews with adults with IDD/ELL and caregivers of adults with IDD/ELL. To build evidence around the principles described in the tool, RTI conducted interviewer-administered surveys with 100 caregivers who support people with IDD/ELL. During the interviews, we presented caregivers with stimuli (portions of a communication product) that either did or did not apply a single principle and asked which would be easier for the person they support to understand. Across all 14 principles tested, the caregiver respondents indicated that the principle-based version would be easier for the person they support to understand compared with the non-principle-based version(s). These findings provide additional evidence to support the principles included in CDC's Tool for Developing Products for People with IDD/ELL.
Language	English
Publishing date	2023-06-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare11121742
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Building Evidence for Principles to Guide the Development of Products for Adults with Intellectual and Developmental Disabilities and Extreme Low Literacy—A Product Development Tool

Linda Squiers / Molly M. Lynch / Sidney L. Holt / Aileen Rivell / Kathleen Walker / Stacy Robison / Elizabeth W. Mitchell / Alina L. Flores

Healthcare, Vol 11, Iss 1742, p

2023 Volume 1742

Abstract	This article presented a new product development tool for adults with intellectual and developmental disabilities (IDD) developed by the Centers for Disease Control and Prevention (CDC). People with IDD who also have extreme low literacy (ELL) have unique communication needs; public health communicators often face challenges developing effective communication materials for this audience. To support CDC communication specialists with the development of communication products for adults with IDD/ELL, CDC, with its partners RTI International and CommunicateHealth, created a product development tool for this audience through literature review, expert input, and interviews with adults with IDD/ELL and caregivers of adults with IDD/ELL. To build evidence around the principles described in the tool, RTI conducted interviewer-administered surveys with 100 caregivers who support people with IDD/ELL. During the interviews, we presented caregivers with stimuli (portions of a communication product) that either did or did not apply a single principle and asked which would be easier for the person they support to understand. Across all 14 principles tested, the caregiver respondents indicated that the principle-based version would be easier for the person they support to understand compared with the non-principle-based version(s). These findings provide additional evidence to support the principles included in CDC’s Tool for Developing Products for People with IDD/ELL.
Keywords	intellectual disabilities ; developmental disabilities ; low literacy ; health communication ; information needs ; Medicine ; R
Subject code	360
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Active older adults goal setting outcomes for engaging in a physical activity app and the motivation characteristics of these goals (MOVEAGE-ACT)

Aileen M. Lynch / Sean Kilroy / Heather McKee / Fintan Sheerin / Monique Epstein / Ariane Girault / Pierre Gillois / Jean Luc Bosson / Carole Rolland / Mary Harkin / Ciarán McKinney / Gabrielle McKee

Preventive Medicine Reports, Vol 31, Iss , Pp 102084- (2023)

2023

Abstract: Approximately 70% of older adults do not meet physical activity (PA) guidelines. While many interventions, are used in promoting PA, few target older adults or include substantial behavioural change techniques. Setting PA goals is often used but there is ...

Abstract	Approximately 70% of older adults do not meet physical activity (PA) guidelines. While many interventions, are used in promoting PA, few target older adults or include substantial behavioural change techniques. Setting PA goals is often used but there is less research on goal setting outcomes, like improving health, preventing age effects, improving flexibility, goals that have been associated with increased likelihood of maintenance of PA. To understand the concept more fully in this cohort, the aim of this study was to identify older adults’ goal setting outcomes - the purpose of engaging in a PA app and through analysis determine the motivation characteristics of these.A cross-sectional, qualitative online survey was completed by 24, 60+, community dwelling, mostly active, French and Irish older adults. Thematic template analysis was used, and the motivation of these outcomes was assessed using the Self-Determination Theory of Motivation.The themes were: improving/staying healthy or physically active, maintaining functional aspects of physical health, continuing to do the things I want, sustaining mental wellbeing, and preventing disease and aging. Individuals cited goal setting outcomes that were generic, specific or both, and goals related to maintenance of PA and prevention of aging decline, were cited most. The motivation characteristics of these goals in mostly active older adults were autonomous and internally driven.Interventions, including apps, for older adults that encourage them to set specific goal setting outcomes/purposes for PA, are likely to generate stronger internally driven motivation, enhance ownership and participation, and may therefore increase effectiveness.
Keywords	Physical activity ; Older adults ; Behavioral change ; Goal setting outcomes ; Motivation ; App ; Medicine ; R
Subject code	300
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Active older adults goal setting outcomes for engaging in a physical activity app and the motivation characteristics of these goals (MOVEAGE-ACT).

Lynch, Aileen M / Kilroy, Sean / McKee, Heather / Sheerin, Fintan / Epstein, Monique / Girault, Ariane / Gillois, Pierre / Bosson, Jean Luc / Rolland, Carole / Harkin, Mary / McKinney, Ciarán / McKee, Gabrielle

Preventive medicine reports

2022 Volume 31, Page(s) 102084

Abstract	Approximately 70% of older adults do not meet physical activity (PA) guidelines. While many interventions, are used in promoting PA, few target older adults or include substantial behavioural change techniques. Setting PA goals is often used but there is less research on goal setting outcomes, like improving health, preventing age effects, improving flexibility, goals that have been associated with increased likelihood of maintenance of PA. To understand the concept more fully in this cohort, the aim of this study was to identify older adults' goal setting outcomes - the purpose of engaging in a PA app and through analysis determine the motivation characteristics of these. A cross-sectional, qualitative online survey was completed by 24, 60+, community dwelling, mostly active, French and Irish older adults. Thematic template analysis was used, and the motivation of these outcomes was assessed using the Self-Determination Theory of Motivation. The themes were: improving/staying healthy or physically active, maintaining functional aspects of physical health, continuing to do the things I want, sustaining mental wellbeing, and preventing disease and aging. Individuals cited goal setting outcomes that were generic, specific or both, and goals related to maintenance of PA and prevention of aging decline, were cited most. The motivation characteristics of these goals in mostly active older adults were autonomous and internally driven. Interventions, including apps, for older adults that encourage them to set specific goal setting outcomes/purposes for PA, are likely to generate stronger internally driven motivation, enhance ownership and participation, and may therefore increase effectiveness.
Language	English
Publishing date	2022-12-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2785569-7
ISSN	2211-3355
ISSN	2211-3355
DOI	10.1016/j.pmedr.2022.102084
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Impact of the COVID-19 pandemic on cancer care in Ireland - Perspectives from a COVID-19 and Cancer Working Group.

O'Reilly, Seamus / Kathryn Carroll, Hailey / Murray, Deirdre / Burke, Louise / McCarthy, Triona / O'Connor, Robert / Kilty, Claire / Lynch, Sonya / Feighan, Jennifer / Cloherty, Maeve / Fitzpatrick, Patricia / Falvey, Katrina / Murphy, Verena / Jane O'Leary, Mary / Gregg, Sophie / Young, Leonie / McAuliffe, Eilish / Hegarty, Josephine / Gavin, Anna /

Lawler, Mark / Kavanagh, Paul / Spillane, Susan / McWade, Terry / Heffron, Mairead / Ryan, Karen / Kelly, Paul J / Murphy, Aileen / Corrigan, Mark / Redmond, H Paul / Redmond, Patrick / Walsh, Paul M / Tierney, Paula / Zhang, Mengyang / Bennett, Kathleen / Mullooly, Maeve

Journal of cancer policy

2023 Volume 36, Page(s) 100414

Abstract: Upon the COVID-19 pandemic onset in Ireland, cancer service disruptions occurred due to prioritisation of COVID-19 related care, redeployment of staff, initial pausing of screening, diagnostic, medical and surgical oncology procedures, staff shortages ... ...

Abstract	Upon the COVID-19 pandemic onset in Ireland, cancer service disruptions occurred due to prioritisation of COVID-19 related care, redeployment of staff, initial pausing of screening, diagnostic, medical and surgical oncology procedures, staff shortages due to COVID-19 infection and impacts on the physical and mental health of cancer healthcare workers. This was coupled with reluctance among people with symptoms suspicious for cancer to attend for clinical evaluation, due to concerns of contracting the virus. This was further compounded by a cyber-attack on national health service IT systems on May 14th 2021. The Irish Cancer Society, a national cancer charity with a role in advocacy, research and patient supports, convened a multi-disciplinary stakeholder group (COVID-19 and Cancer Working Group) to reflect on and understand the impact of the pandemic on cancer patients and services in Ireland, and discuss potential mitigation strategies. Perspectives on experiences were gathered across domains including timeliness of data acquisition and its conversion into intelligence, and the resourcing of cancer care to address cancer service impacts. The group highlighted aspects for future research to understand the long-term pandemic impact on cancer outcomes, while also highlighting potential strategies to support cancer services, build resilience and address delayed diagnosis. Additional measures include the need for cancer workforce recruitment and retention, increased mental health supports for both patients and oncology professionals, improvements to public health messaging, a near real-time multimodal national cancer database, and robust digital and physical infrastructure to mitigate impacts of the current pandemic and future challenges to cancer care systems.
MeSH term(s)	Humans ; Pandemics ; COVID-19/epidemiology ; Ireland/epidemiology ; State Medicine ; Neoplasms/epidemiology
Language	English
Publishing date	2023-02-24
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ISSN	2213-5383
ISSN (online)	2213-5383
DOI	10.1016/j.jcpo.2023.100414
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Internet Use by Parents of Children With Rare Conditions: Findings From a Study on Parents' Web Information Needs.

Nicholl, Honor / Tracey, Catherine / Begley, Thelma / King, Carole / Lynch, Aileen M

Journal of medical Internet research

2017 Volume 19, Issue 2, Page(s) e51

Abstract: Background: Parents of children with rare conditions increasingly use the Internet to source information on their child's condition. This study reports on part of a larger study whose overall aim was to identify the Internet use by parents when seeking ... ...

Abstract	Background: Parents of children with rare conditions increasingly use the Internet to source information on their child's condition. This study reports on part of a larger study whose overall aim was to identify the Internet use by parents when seeking information on their child's rare condition, with the specific purpose of using the findings to aid in the development of a website specifically designed to meet the parents' needs. It presents findings on why these parents use the Internet, the information and support content they source, and the impact these resources have on their capacity to care for and manage their child's condition. Objective: To (1) ascertain parents' general Internet usage patterns, (2) identify the nature of the information parents most frequently searched for, and (3) determine the effect the Internet-sourced information had on parents of children with rare conditions. Methods: Data collection was conducted in 2 parts: Part 1 was a focus group interview (n=8) to inform the development of the questionnaire, and Part 2 was a questionnaire (Web- and paper-based). All respondents (N=128) completed the questionnaire using the Internet. Results: Parents frequently and habitually used the Internet and social media to gather information on their child's condition. These Web-based resources provide parents with a parent-to-parent support platform that allows them to share their experiences and information with other parents, which, the respondents considered, improved their knowledge and understanding of their child's condition. The respondents also reported that these resources positively impacted on their decision making, care, and management of their child's condition. However, they reported receiving mixed responses when wishing to engage and share with health care professionals their Internet and social media interactions and information outcomes. Conclusions: This study adds to the emerging body of research on the Internet use by parents of children with rare conditions to source information on their child's condition. The evolving and ever increasing parent-to-parent support systems via social media are impacting on parents' capacity to manage their children. Implications for practice include health care professionals' response to this knowledge and capacity shift, and the significance of these changes when interacting with parents. The key message of this study was that parents of children with rare conditions are habitual users of the Internet to source information about their children's conditions. Social media, especially Facebook, has an increasing role in the lives of these parents for information and support. Parents' interest in information gathering and sharing includes a desire for shared dialogue with health care professionals.
MeSH term(s)	Adolescent ; Adult ; Child ; Child, Preschool ; Decision Making ; Female ; Health Information Exchange/utilization ; Humans ; Internet/utilization ; Male ; Parents/education ; Physician-Patient Relations ; Rare Diseases/diagnosis ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2017-02-28
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2028830-X
ISSN	1438-8871 ; 1439-4456
ISSN (online)	1438-8871
ISSN	1439-4456
DOI	10.2196/jmir.5834
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Article ; Online: Prevalence of tobacco smoking among European migrants residing in EU 15 countries: a quantitative systematic review protocol.

Byrne, Gobnait / Murphy, Fiona / Eustace-Cook, Jessica / Mooney, Mary / O'Brien, Frances / O'Donnell, Sharon / Corry, Margarita / Lynch, Aileen M / Neenan, Kathleen / McKee, Gabrielle

JBI evidence synthesis

2020 Volume 18, Issue 12, Page(s) 2647–2657

Abstract: Objectives: The objective of this systematic review is to summarize the prevalence of tobacco smoking in European migrants residing in EU 15 countries.: Introduction: Most of the migration within the World Health Organization European Region is ... ...

Abstract	Objectives: The objective of this systematic review is to summarize the prevalence of tobacco smoking in European migrants residing in EU 15 countries. Introduction: Most of the migration within the World Health Organization European Region is intracontinental. The prevalence of smoking varies greatly across the European Region. Migrants may choose to adopt the smoking behaviors of their host countries or retain the smoking behaviors of their countries of origin. Several studies have identified the high prevalence of smoking of some migrant groups in comparison to their host countries, but no systematic reviews have been completed on intracontinental migrants within the European Region. Inclusion criteria: Epidemiological studies, which include data on the prevalence of tobacco smoking in European migrants aged ≥ 15 years of age living in the following EU 15 countries host countries for ≥ 1 year: Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. Methods: MEDLINE, Embase, CINAHL, PsycINFO, ASSIA, and Web of Science will be searched to identify published studies. General gray literature (eg, Open Grey) as well as gray literature for migrants (Migrant Health Research Portal) and tobacco will be searched. The JBI methodology for systematic reviews of prevalence will be used in this review. Data synthesis will use meta-analysis where appropriate and narrative synthesis.
MeSH term(s)	Adolescent ; Adult ; Aged ; Europe/epidemiology ; Female ; Humans ; Male ; Meta-Analysis as Topic ; Middle Aged ; Prevalence ; Systematic Reviews as Topic ; Tobacco Smoking/epidemiology ; Transients and Migrants/statistics & numerical data ; Young Adult
Language	English
Publishing date	2020-06-19
Publishing country	United States
Document type	Journal Article
ISSN	2689-8381
ISSN (online)	2689-8381
DOI	10.11124/JBISRIR-D-19-00396
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Second-trimester Ultrasound and Neuropathologic Findings in Congenital Zika Virus Infection.

Ho, Cheng-Ying / Castillo, Nicolas / Encinales, Liliana / Porras, Alexandra / Mendoza, Alejandro Rico / Lynch, Rebecca / Nemirovsky, Amy / Mantus, Grace / DeBiasi, Roberta L / Bethony, Jeffrey M / Simon, Gary L / Chang, Aileen Y

The Pediatric infectious disease journal

2018 Volume 37, Issue 12, Page(s) 1290–1293

Abstract: Zika virus is a mosquito-borne virus that causes congenital Zika syndrome, characterized by microcephaly and other fetal brain anomalies. This case report presents a case of Zika virus-related fetal brain anomalies including pathologic evidence of ... ...

Abstract	Zika virus is a mosquito-borne virus that causes congenital Zika syndrome, characterized by microcephaly and other fetal brain anomalies. This case report presents a case of Zika virus-related fetal brain anomalies including pathologic evidence of cerebral neuronal apoptosis and macrophage infiltrates and intracerebral calcification, ventriculomegaly and corpus callosum dysgenesis detected by ultrasound at 18 weeks of pregnancy.
MeSH term(s)	Adult ; Brain/diagnostic imaging ; Brain/pathology ; Female ; Humans ; Nervous System Diseases/diagnostic imaging ; Nervous System Diseases/virology ; Pregnancy ; Pregnancy Complications, Infectious/diagnostic imaging ; Pregnancy Trimester, Second ; Ultrasonography, Prenatal/methods ; Zika Virus ; Zika Virus Infection/congenital ; Zika Virus Infection/diagnostic imaging
Language	English
Publishing date	2018-10-31
Publishing country	United States
Document type	Case Reports ; Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	392481-6
ISSN	1532-0987 ; 0891-3668
ISSN (online)	1532-0987
ISSN	0891-3668
DOI	10.1097/INF.0000000000002080
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Article ; Online: Augmented Zika and Dengue Neutralizing Antibodies Are Associated With Guillain-Barré Syndrome.

Lynch, Rebecca M / Mantus, Grace / Encinales, Liliana / Pacheco, Nelly / Li, Guangzhao / Porras, Alexandra / Mendoza, Alejandro R / Peng, Jin / Rengifo-Pardo, Monica / Cruz, Magelda Montoya / Harris, Eva / Bethony, Jeff M / Simon, Gary L / Chang, Aileen Y

The Journal of infectious diseases

2018 Volume 219, Issue 1, Page(s) 26–30

Abstract: The role of neutralizing antibodies in Zika-induced Guillain-Barré syndrome (GBS) has not yet been investigated. We conducted a case-control study using sera from the 2016 Zika epidemic in Colombia to determine the neutralizing antibody activity against ... ...

Abstract	The role of neutralizing antibodies in Zika-induced Guillain-Barré syndrome (GBS) has not yet been investigated. We conducted a case-control study using sera from the 2016 Zika epidemic in Colombia to determine the neutralizing antibody activity against Zika virus (ZIKV) and dengue virus serotype 2 (DENV2). We observed increased neutralizing antibody titers against DENV2 in ZIKV-infected individuals compared with uninfected controls and higher titers to both ZIKV and DENV2 in ZIKV-infected patients diagnosed with GBS compared with non-GBS ZIKV-infected controls. These data suggest that high neutralizing antibody titers to DENV and to ZIKV are associated with GBS during ZIKV infection.
MeSH term(s)	Adult ; Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Case-Control Studies ; Colombia/epidemiology ; Dengue/blood ; Dengue/complications ; Dengue/immunology ; Dengue Virus/isolation & purification ; Female ; Guillain-Barre Syndrome/blood ; Guillain-Barre Syndrome/complications ; Guillain-Barre Syndrome/virology ; Humans ; Male ; Middle Aged ; Zika Virus/isolation & purification ; Zika Virus Infection/blood ; Zika Virus Infection/complications ; Zika Virus Infection/immunology
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral
Language	English
Publishing date	2018-08-15
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiy466
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Article ; Online: Antidepressant-associated sexual dysfunction

Agnes Higgins / Michael Nash / Aileen M Lynch

Drug, Healthcare and Patient Safety, Vol 2010, Iss default, Pp 141-

impact, effects, and treatment

2010 Volume 150

Abstract: Agnes Higgins, Michael Nash, Aileen M LynchSchool of Nursing and Midwifery Studies, Trinity College ...

Abstract	Agnes Higgins, Michael Nash, Aileen M LynchSchool of Nursing and Midwifery Studies, Trinity College Dublin, Dublin, IrelandAbstract: Sexual dysfunction is a common side effect of antidepressants and can have significant impact on the person’s quality of life, relationships, mental health, and recovery. The reported incidence of sexual dysfunction associated with antidepressant medication varies considerably between studies, making it difficult to estimate the exact incidence or prevalence. The sexual problems reported range from decreased sexual desire, decreased sexual excitement, diminished or delayed orgasm, to erection or delayed ejaculation problems. There are a number of case reports of sexual side effects, such as priapism, painful ejaculation, penile anesthesia, loss of sensation in the vagina and nipples, persistent genital arousal and nonpuerperal lactation in women. The focus of this article is to explore the incidence, pathophysiology, and treatment of antidepressant iatrogenic sexual dysfunction.Keywords: depression, antidepressant, iatrogenic sexual dysfunction, SSRI, SNRI
Keywords	Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2010-09-01T00:00:00Z
Publisher	Dove Medical Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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