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  1. Article ; Online: KHALID’S MANEUVER; A NEW APPROACH TO GROCCO’S SIGN IN PATIENTS WITH PLEURAL EFFUSION

    Muhammad Khalid Azam / Abdul Latif Khattak / Shazia Naz / Muhammad Tahir Ibrahim / Karamat Hussain Shah Bukhari / Riaz Ahmed

    Pakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 251-

    2020  Volume 255

    Abstract: Objective: To compare the usefulness of Grocco’s sign with an alternative method, Khalid’s maneuver ... Khalid’s maneuver) to elicit disappearance of dullness in Grocco’s triangle were compared in patients ... 95% CI 90.1-95.6) patients by Khalid’s maneuver with statistically insignificant p-value i.e. 0.44 ...

    Abstract Objective: To compare the usefulness of Grocco’s sign with an alternative method, Khalid’s maneuver, which does not require any change in patient’s position to elicit Grocco’s sign. Study Design: A comparative prospective study. Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2019 to Jul 2019. Methodology: A total of 200 patients who were divided into two groups (group A and group B) with 100 patients in each group. Group A was a control group. Group B was subdivided into group B1 containing patients with serous pleural effusion and group B2 containing patients with empyema. Two independent operators were asked to do chest percussion in all patients to elicit Grocco’s sign. Furthermore Positional method and Inspiratory method (Khalid’s maneuver) to elicit disappearance of dullness in Grocco’s triangle were compared in patients with positive Grocco’s sign Statistical significance & 95% confidence interval was calculated using nonparametric unpaired t test (Mann-Whitney U-Test). Results: Grocco’s sign was negative in all patients in group A while it was positive in all patients in group B. In group B1 patients, the percussion dullness disappeared in Grocco’s triangle in 48 (96%) (95% CI 93.2-98.1) patients by the positional method and 46 (92%) (95% CI 90.1-95.6) patients by Khalid’s maneuver with statistically insignificant p-value i.e. 0.44. In group B2 patients, the percussion dullness failed to disappear by both methods. Conclusion: Grocco’s sign helps in assessment of the patients with simple and complex pleural effusion and thus guiding further management decisions early in time. Khalid’s maneuver which has the ability to elicit Grocco’s sign with near similar accuracy provides handy alternative for such patients with comparable p-value to the standard procedure.
    Keywords empyema thorax ; grocco’s sign ; khalid’s maneuver ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Army Medical College Rawalpindi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: KHALID’S MANEUVER; A NEW APPROACH TO GROCCO’S SIGN IN PATIENTS WITH PLEURAL EFFUSION

    Muhammad Khalid Azam / Abdul Latif Khattak / Shazia Naz / Muhammad Tahir Ibrahim / Karamat Hussain Shah Bukhari / Riaz Ahmed

    Pakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1251-

    2020  Volume 1255

    Abstract: Objective: To compare the usefulness of Grocco’s sign with an alternative method, Khalid’s maneuver ... Khalid’s maneuver) to elicit disappearance of dullness in Grocco’s triangle were compared in patients ... 95% CI 90.1-95.6) patients by Khalid’s maneuver with statistically insignificant p-value i.e. 0.44 ...

    Abstract Objective: To compare the usefulness of Grocco’s sign with an alternative method, Khalid’s maneuver, which does not require any change in patient’s position to elicit Grocco’s sign. Study Design: A comparative prospective study. Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2019 to Jul 2019. Methodology: A total of 200 patients who were divided into two groups (group A and group B) with 100 patients in each group. Group A was a control group. Group B was subdivided into group B1 containing patients with serous pleural effusion and group B2 containing patients with empyema. Two independent operators were asked to do chest percussion in all patients to elicit Grocco’s sign. Furthermore Positional method and Inspiratory method (Khalid’s maneuver) to elicit disappearance of dullness in Grocco’s triangle were compared in patients with positive Grocco’s sign Statistical significance & 95% confidence interval was calculated using nonparametric unpaired t test (Mann-Whitney U-Test). Results: Grocco’s sign was negative in all patients in group A while it was positive in all patients in group B. In group B1 patients, the percussion dullness disappeared in Grocco’s triangle in 48 (96%) (95% CI 93.2-98.1) patients by the positional method and 46 (92%) (95% CI 90.1-95.6) patients by Khalid’s maneuver with statistically insignificant p-value i.e. 0.44. In group B2 patients, the percussion dullness failed to disappear by both methods. Conclusion: Grocco’s sign helps in assessment of the patients with simple and complex pleural effusion and thus guiding further management decisions early in time. Khalid’s maneuver which has the ability to elicit Grocco’s sign with near similar accuracy provides handy alternative for such patients with comparable p-value to the standard procedure.
    Keywords empyema thorax ; grocco’s sign ; khalid’s maneuver ; paravertebral triangle pleural effusion ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Army Medical College Rawalpindi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: The Prevalence of Congenital Heart Diseases in Syndromic Children at King Khalid National Guard Hospital from 2005 to 2016.

    Abduljawad, Elaf M / AlHarthi, Ahad / AlMatrafi, Samah A / Hussain, Mawaddah / Shawli, Aiman / Waggass, Rahaf

    Cureus

    2020  Volume 12, Issue 4, Page(s) e7891

    Abstract: ... on all dysmorphic syndrome patients who attended genetic clinics at King Khalid National Guard Hospital in King ...

    Abstract Background Congenital heart diseases (CHDs) are abnormalities that present in the heart since birth and are one of the leading causes of infant mortality in the world. CHDs are more common among children with dysmorphic syndromes. The current study aims to estimate the prevalence of many CHDs in different dysmorphic syndromes. Methods This was a retrospective chart review study conducted on all dysmorphic syndrome patients who attended genetic clinics at King Khalid National Guard Hospital in King Abdulaziz Medical City (KAMC), Jeddah, Saudi Arabia from 2005 to 2016. Dysmorphic pediatric patients less than 14 years old who had genetic testing to confirm their diagnosis were included in the study. Patients who did not have any previous echocardiography were excluded. Results A total of 212 individuals (47% males and 53% females) were included. Eighty-five percent of Down syndrome patients had CHDs, and the most common CHD was an atrial septal defect (ASD) (51%). In patients with Turner syndrome, 45% of them had CHDs, and bicuspid aortic valve (BAV) (40%) was the most common defect. In DiGeorge syndrome, 81% of patients had CHDs, and ventricular septal defect (VSD) (41%) was the most common. In Williams syndrome, 83% of patients had CHDs. All patients with Noonan, Edwards, CHARGE (coloboma, heart defects, atresia choanae (also known as choanal atresia), growth retardation, genital abnormalities, and ear abnormalities), and Rubinstein-Taybi syndromes were found to have CHDs. In Patau syndrome and Joubert syndrome, 50% of patients in each had CHDs. Patients with Prader Willi syndrome had normal findings in the echocardiogram. Conclusion The highest prevalence of CHDs was found in Down syndrome. This study has a significant impact on the future of managing and directing the resources to improve the quality of life for syndromic patients. Further studies are needed to confirm these findings and to increase the local data in the field of CHDs in Saudi Arabia among syndromic patients.
    Language English
    Publishing date 2020-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7891
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Entrance Skin Dose Measurement for Diagnostic Spinal Radiographic Examinations in King Khalid Hospital, Saudi Arabia

    Yousif Mohamed Abdallah / Nouf Hussain Abuhadi

    Journal of Clinical and Diagnostic Research, Vol 14, Iss 3, Pp TC01-TC

    A Prospective Study

    2020  Volume 04

    Abstract: Introduction: Radiographic examinations has necessary role in the identification of spine injuries and pathologies. There are many hazards associated with the radiation exposure which included the acute (radiation injury) and chronic exposure effects ( ... ...

    Abstract Introduction: Radiographic examinations has necessary role in the identification of spine injuries and pathologies. There are many hazards associated with the radiation exposure which included the acute (radiation injury) and chronic exposure effects (cancer). Aim: To measure the entrance skin dose of spine vertebra (cervical, thoracic, lumbar and sacral) in AP and Lateral Views. Materials and Methods: A prospective study was conducted with a sample of 250 adults and 100 paediatrics patients. The imaging apparatus, which was used in this study was Siemens with pipe Filtration 2.0-3.0 mm of AL/70 KVp. The parameters of patients collected were patients’ characteristics and exposure factors. The dose was measured using Entrance Skin Dose (ESD) and International Atomic Energy Agency (IAEA) formula and compared nationally and internationally. Results: The measured exposure parameters were 78.1±5.7 and 19.9±7.8 for the machine kVp and mAs, respectively. The measured ESD dose for cervical, thoracic, Lumbosacral (AP and LAT.) and sacral (AP) for adult population were 0.11±0.06 mGy and 0.15±0.07 mGy, (0.86±0.06 and 0.91±0.09 mGy, 0.88±0.07 and 0.92±0.09 mGy and 0.25±0.04 mGy, respectively. Similarly, measured ESD dose for cervical, thoracic, Lumbosacral (AP and LAT.) and sacral (AP) for paediatrics population were 0.09±0.01 mGy and 0.12±0.07 mGy, 0.32±0.03 mGy and 0.42±0.06 mGy, 0.38±0.06 and 0.74±0.08 mGy and 0.09±0.01, respectively. Conclusion: The results of the study were within the range of permissible dose of the spine vertebrae dose (4.0-30.0 mGy). More studies are recommended to study radiation dose of the spine vertebrae with large patients’ data and more than one modalities to compare.
    Keywords radiation dose ; traumatic ; vertebra ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Online: Macrophage Activation : Biology and Disease

    Hussain Bhat, Khalid

    2020  

    Keywords Immunology
    Size 1 electronic resource (132 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021046347
    ISBN 9781789855746 ; 1789855748
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book ; Online ; E-Book: Oral health and herbal medicine

    Hakeem, Khalid Rehman / Abdul, Waseem Mohammed / Hussain, Mohd Muzzammil / Razvi, Syed Shoeb Iqbal

    (SpringerBriefs in public health)

    2019  

    Author's details Khalid Rehman Hakeem, Waseem Mohammed Abdul, Mohd Muzzammil Hussain, Syed Shoeb Iqbal Razvi
    Series title SpringerBriefs in public health
    Language English
    Size 1 Online-Ressource (x, 46 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019930228
    ISBN 978-3-030-04336-0 ; 9783030043353 ; 3-030-04336-3 ; 3030043355
    DOI 10.1007/978-3-030-04336-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article ; Online: Dysphagia aortica presenting as failure of performing transoesophageal echocardiogram.

    Khalid, Hussain / Wang, Wei / Ruzieh, Mohammed

    European heart journal. Case reports

    2024  Volume 8, Issue 1, Page(s) ytae007

    Language English
    Publishing date 2024-01-06
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytae007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Adjuvant Alpelisib Therapy for Congenital Hyperinsulinism.

    Dauleh, Hajar / Amin, Rasha / Pasha, Maheen / Hussain, Khalid

    The New England journal of medicine

    2024  Volume 390, Issue 4, Page(s) 379–380

    MeSH term(s) Humans ; Congenital Hyperinsulinism/drug therapy ; Thiazoles/therapeutic use ; Class I Phosphatidylinositol 3-Kinases/therapeutic use
    Chemical Substances Alpelisib (08W5N2C97Q) ; Thiazoles ; Class I Phosphatidylinositol 3-Kinases (EC 2.7.1.137)
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2312807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Vaccinomics-Aided Development of a Next-Generation Chimeric Vaccine against an Emerging Threat:

    Khalid, Kashaf / Hussain, Tajamul / Jamil, Zubia / Alrokayan, Khalid Salman / Ahmad, Bashir / Waheed, Yasir

    Vaccines

    2022  Volume 10, Issue 10

    Abstract: Mycoplasma ... ...

    Abstract Mycoplasma genitalium
    Language English
    Publishing date 2022-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10101720
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: On characterization of entropy measure using logarithmic regression model for Copper(II) Fluoride.

    Siddiqui, Muhammad Kamran / Hussain, Mazhar / Javed, Sana / Khalid, Sadia / Noor, Tayyaba / Tolasa, Fikadu Tesgera

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0300757

    Abstract: The versatile uses of Copper(II) Fluoride (CuF2) are well known; these include its usage as a precursor in chemical synthesis as well as its contribution to the creation of sophisticated materials and electronics. There are interesting opportunities to ... ...

    Abstract The versatile uses of Copper(II) Fluoride (CuF2) are well known; these include its usage as a precursor in chemical synthesis as well as its contribution to the creation of sophisticated materials and electronics. There are interesting opportunities to study the interactions between these elements because of their unique crystal structure, which contains copper ions and fluoride anions. Its potential in optoelectronic devices and conductive qualities also make it a viable material for next-generation technologies. To better understand the structural properties of CuF2 and how they affect its entropy, we present new Zagreb indices in this study and use them to calculate entropy measures. We also build a regression model to clarify the relationship between the calculated indices and entropy levels. The findings of our investigation offer significant understanding regarding the ability of the suggested Zagreb indices to extract meaningful content and their correlation with entropy in the context of CuF2. This information is important for understanding CuF2 alloys and for exploring related complex materials.
    MeSH term(s) Fluorides ; Copper/chemistry ; Entropy
    Chemical Substances Fluorides (Q80VPU408O) ; Copper (789U1901C5)
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0300757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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