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  1. Article: Cutaneous hyperpigmentation following nonpermanent henna tattoo.

    Bukhari, Iqbal A

    Saudi medical journal

    2005  Volume 26, Issue 1, Page(s) 142–144

    Abstract: Decorative henna skin painting can provoke severe reactions in the skin. We report 3 cases ... of unusual and persistent hyperpigmentation following nonpermanent henna tattoo, which alerted us to identify ...

    Abstract Decorative henna skin painting can provoke severe reactions in the skin. We report 3 cases of unusual and persistent hyperpigmentation following nonpermanent henna tattoo, which alerted us to identify an additional side effect.
    MeSH term(s) Adult ; Female ; Humans ; Hyperpigmentation/chemically induced ; Naphthoquinones/adverse effects ; Tattooing/adverse effects
    Chemical Substances Naphthoquinones ; lawsone (TLH4A6LV1W)
    Language English
    Publishing date 2005-01
    Publishing country Saudi Arabia
    Document type Case Reports ; Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bioassay-guided isolation of urease and α-chymotrypsin inhibitory constituents from the stems of Lawsonia alba Lam. (Henna).

    Uddin, Nizam / Siddiqui, Bina Shaheen / Begum, Sabira / Ali, Muhammad Imran / Marasini, Bishnu P / Khan, Ajmal / Choudhary, M Iqbal

    Fitoterapia

    2013  Volume 84, Page(s) 202–207

    Abstract: Seven constituents were isolated from the stems of Lawsonia alba Lam., following an activity-guided isolation, which include two new constituents, namely lawsorosemarinol (1) and lawsofructose (2), one known compound 2-(β-d-glucopyranosyloxy)-1, 4- ... ...

    Abstract Seven constituents were isolated from the stems of Lawsonia alba Lam., following an activity-guided isolation, which include two new constituents, namely lawsorosemarinol (1) and lawsofructose (2), one known compound 2-(β-d-glucopyranosyloxy)-1, 4-naphthoquinone (3) and four compounds, 4-hydroxy coumarine (4), 3-(4-hyroxyphenyl)-triacontyl-(Z)-propenoate (5), 3-(4-hydroxy-3-methoxyphenyl)-triacontyl-(Z)-propenoate (6) and 7-hydroxy-4-methyl coumarin (7) first time isolated from Lawsonia alba. Their structure elucidation was based on spectroscopic data analyses. Compounds 3 and 7 showed a moderate inhibition of urease activity, while rest of them showed less than 50% inhibition. These compounds did not show any significant inhibition against α-chymotrypsin.
    MeSH term(s) Chymotrypsin/antagonists & inhibitors ; Chymotrypsin/metabolism ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Lawsonia Plant/chemistry ; Molecular Structure ; Plant Stems/chemistry ; Stereoisomerism ; Urease/antagonists & inhibitors ; Urease/metabolism
    Chemical Substances Enzyme Inhibitors ; Chymotrypsin (EC 3.4.21.1) ; alpha-chymotrypsin (EC 3.4.21.1) ; Urease (EC 3.5.1.5)
    Language English
    Publishing date 2013-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2012.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Bioassay-guided isolation of urease and α-chymotrypsin inhibitory constituents from the stems of Lawsonia alba Lam. (Henna)

    Uddin, Nizam / Siddiqui, Bina Shaheen / Begum, Sabira / Ali, Muhammad Imran / Marasini, Bishnu P / Khan, Ajmal / Choudhary, M. Iqbal

    Fitoterapia. 2013 Jan., v. 84

    2013  

    Abstract: Seven constituents were isolated from the stems of Lawsonia alba Lam., following an activity-guided isolation, which include two new constituents, namely lawsorosemarinol (1) and lawsofructose (2), one known compound 2-(β-d-glucopyranosyloxy)-1, 4- ... ...

    Abstract Seven constituents were isolated from the stems of Lawsonia alba Lam., following an activity-guided isolation, which include two new constituents, namely lawsorosemarinol (1) and lawsofructose (2), one known compound 2-(β-d-glucopyranosyloxy)-1, 4-naphthoquinone (3) and four compounds, 4-hydroxy coumarine (4), 3-(4-hyroxyphenyl)-triacontyl-(Z)-propenoate (5), 3-(4-hydroxy-3-methoxyphenyl)-triacontyl-(Z)-propenoate (6) and 7-hydroxy-4-methyl coumarin (7) first time isolated from Lawsonia alba. Their structure elucidation was based on spectroscopic data analyses. Compounds 3 and 7 showed a moderate inhibition of urease activity, while rest of them showed less than 50% inhibition. These compounds did not show any significant inhibition against α-chymotrypsin.
    Keywords Lawsonia inermis ; coumarin ; spectroscopy ; stems ; urease
    Language English
    Dates of publication 2013-01
    Size p. 202-207.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2012.10.007
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: The importance of cell-mediated immunity in COVID-19 - An opinion.

    Iqbal, Henna

    Medical hypotheses

    2020  Volume 143, Page(s) 110152

    MeSH term(s) Antibodies ; Betacoronavirus ; Biomarkers ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/immunology ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunity, Cellular ; Models, Theoretical ; Pandemics ; Pneumonia, Viral/immunology ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2
    Chemical Substances Antibodies ; Biomarkers
    Keywords covid19
    Language English
    Publishing date 2020-07-31
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The importance of cell-mediated immunity in COVID-19 – An opinion

    Iqbal, Henna

    Medical Hypotheses

    2020  Volume 143, Page(s) 110152

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110152
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: A Case of Previously Undiagnosed Systemic Lupus Erythematosus and

    Iqbal, Henna / Screws, Benny / Khan, Muhammad S

    Case reports in rheumatology

    2023  Volume 2023, Page(s) 3686772

    Abstract: Diffuse alveolar hemorrhage (DAH) is described as the collection of blood in alveolar spaces caused by damaged pulmonary vasculature. It often presents as a life-threatening medical emergency that requires urgent medical intervention along with timely ... ...

    Abstract Diffuse alveolar hemorrhage (DAH) is described as the collection of blood in alveolar spaces caused by damaged pulmonary vasculature. It often presents as a life-threatening medical emergency that requires urgent medical intervention along with timely diagnosis and management of the underlying cause. We hereby report a 19-year-old female who presented with clinical and radiological characteristics consistent with DAH. Laboratory workup studies revealed a diagnosis of systemic lupus erythematosus (SLE) as well as
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2666708-3
    ISSN 2090-6897 ; 2090-6889
    ISSN (online) 2090-6897
    ISSN 2090-6889
    DOI 10.1155/2023/3686772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A classic case of Capnocytophaga induced septic shock with multi-organ failure after a dog bite in an asplenic patient.

    Duncan, Myles Nicholas / Ahuja, Monica / Khan, Muhammad Suhaib / Iqbal, Henna

    IDCases

    2023  Volume 32, Page(s) e01808

    Abstract: We hereby report a case of a 40-year-old male with a recent dog bite, a past history of immune thrombocytopenic purpura (ITP) and therapeutic splenectomy. He presented to the hospital with abdominal pain and shortness of breath, which progressed to ... ...

    Abstract We hereby report a case of a 40-year-old male with a recent dog bite, a past history of immune thrombocytopenic purpura (ITP) and therapeutic splenectomy. He presented to the hospital with abdominal pain and shortness of breath, which progressed to sepsis and disseminated intravascular coagulation (DIC). Based on clinical presentation,
    Language English
    Publishing date 2023-05-23
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2023.e01808
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A quality improvement approach to integrating social determinants of health objectives into pediatric simulation.

    Feick, Megan / Iqbal, Ammarah U / Boolchandani, Henna / Kandil, Sarah / Johnston, Lindsay / Soma, Gauthami / Cordone, Alexis / Auerbach, Marc / Tiyyagura, Gunjan

    AEM education and training

    2023  Volume 7, Issue 5, Page(s) e10910

    Abstract: Background: Health disparities and the unequal distribution of social resources impact health outcomes. By considering social determinants of health (SDH), clinicians can provide holistic and equitable care. However, barriers such as lack of time or ... ...

    Abstract Background: Health disparities and the unequal distribution of social resources impact health outcomes. By considering social determinants of health (SDH), clinicians can provide holistic and equitable care. However, barriers such as lack of time or understanding of the relevance of SDH to patient care prevent providers from addressing SDH. Simulation curricula may improve learners' ability to address SDH in practice.
    Objectives: The primary objective was to increase the percentage of pediatric emergency simulations that included SDH objectives from 5% to 50% in 12 months at one institution. As a balancing metric, we examined whether trainees approved the incorporation of SDH objectives.
    Methods: Using the Model for Improvement approach, we conducted interviews of residents and simulation facilitators to identify challenges to integrating SDH objectives into the simulation curriculum. Review of interviews and visual representation of the system helped identify key drivers in the process. A team of simulation leaders, residents, and fellows met regularly to develop simulation cases with embedded SDH objectives. Using a plan, do, study, act approach, we tested, refined, and implemented interventions including engaging residency program and SDH leadership, piloting cases, providing facilitators concise resources, inviting SDH-specific experts to co-debrief, and eliciting and incorporating learner and facilitator feedback to improve cases. SDH topics include homelessness, undocumented status, and racism.
    Results: Prior to the start of the quality improvement work, SDH were rarely incorporated into emergency simulations for pediatric residents. A p-chart was used to track the percentage of monthly cases that incorporated SDH topics. During the study period, the percentage of simulations including SDH topics increased to 57% per month. Most trainees (94%) welcomed incorporating SDH objectives.
    Conclusions: Using the Model for Improvement, we incorporated SDH objectives into pediatric resident emergency simulations. Next steps include examining effectiveness of the curriculum, dissemination to additional learners, and examining sustainability in practice.
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article
    ISSN 2472-5390
    ISSN (online) 2472-5390
    DOI 10.1002/aet2.10910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Co-immunoprecipitation for Identifying Protein-Protein Interactions in Borrelia burgdorferi.

    Iqbal, Henna / Akins, Darrin R / Kenedy, Melisha R

    Methods in molecular biology (Clifton, N.J.)

    2017  Volume 1690, Page(s) 47–55

    Abstract: Co-immunoprecipitation can be utilized to study protein-protein interactions from various environments, cell types, or tissues. Herein, we describe a co-immunoprecipitation protocol that can be used to examine protein complexes found in the pathogenic ... ...

    Abstract Co-immunoprecipitation can be utilized to study protein-protein interactions from various environments, cell types, or tissues. Herein, we describe a co-immunoprecipitation protocol that can be used to examine protein complexes found in the pathogenic spirochete Borrelia burgdorferi. The method outlined here has successfully identified known and unknown members of borrelial protein complexes and is an efficient method for studying protein interactions in this pathogenic spirochete.
    MeSH term(s) Animals ; Bacterial Proteins/metabolism ; Borrelia burgdorferi/physiology ; Cell Culture Techniques/methods ; Humans ; Immunoprecipitation/methods ; Lyme Disease/metabolism ; Protein Interaction Mapping/methods ; Protein Interaction Maps
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2017-10-14
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-4939-7383-5_4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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