LIVIVO - Search results -

Search results

Result 1 - 10 of total 1881

Search options

Article ; Online: Dos nuevos casos de sindrome de Leigh por mutacion m.13513G>A en el gen MTND5.

Jimenez-Legido, M / Bernardino-Cuesta, B / Lopez-Marin, L / Cantarin-Extremera, V / Blazquez-Encinar, A / Martin-Casanueva, M A / Gutierrez-Solana, L G

Revista de neurologia

2019 Volume 68, Issue 7, Page(s) 312–314

Title translation	Two new cases of Leigh syndrome caused by mutation m.13513G> A in the MTND5 gene.
MeSH term(s)	Blepharoptosis/genetics ; DNA, Mitochondrial/genetics ; Disease Progression ; Electron Transport Complex I/genetics ; Electron Transport Complex I/physiology ; Female ; Fetal Growth Retardation/genetics ; Gastrointestinal Diseases/genetics ; Genetic Heterogeneity ; Humans ; Infant ; Intellectual Disability/genetics ; Leigh Disease/genetics ; Male ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/physiology ; Mutation, Missense ; Ophthalmoplegia/genetics ; Phenotype ; Point Mutation ; Wolff-Parkinson-White Syndrome/genetics
Chemical Substances	DNA, Mitochondrial ; Mitochondrial Proteins ; MT-ND5 protein, human (EC 1.6.99.3) ; Electron Transport Complex I (EC 7.1.1.2)
Language	Spanish
Publishing date	2019-03-21
Publishing country	Spain
Document type	Case Reports ; Letter
ZDB-ID	1468278-3
ISSN	1576-6578 ; 0210-0010
ISSN (online)	1576-6578
ISSN	0210-0010
DOI	10.33588/rn.6807.2018393
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5003: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Re: Gazzeri R, Galarza M, Neroni M, et al. Fulminating septicemia secondary to oxygen-ozone therapy for lumbar disc herniation: case report. Spine 2007;32:E121-3.

Clavo, Bernardino / Robaina, Francisco / Kovacs, Francisco / Urrútia, Gerard

Spine

2007 Volume 32, Issue 18, Page(s) 2036; author reply 2037

MeSH term(s)	Humans ; Intervertebral Disc/microbiology ; Intervertebral Disc/surgery ; Intervertebral Disc Displacement/microbiology ; Intervertebral Disc Displacement/surgery ; Lumbar Vertebrae/microbiology ; Lumbar Vertebrae/surgery ; Oxygen/administration & dosage ; Oxygen/adverse effects ; Ozone/administration & dosage ; Ozone/adverse effects ; Sepsis/etiology ; Sepsis/microbiology
Chemical Substances	Ozone (66H7ZZK23N) ; Oxygen (S88TT14065)
Language	English
Publishing date	2007-08-15
Publishing country	United States
Document type	Letter
ZDB-ID	752024-4
ISSN	1528-1159 ; 0362-2436
ISSN (online)	1528-1159
ISSN	0362-2436
DOI	10.1097/BRS.0b013e3181342f8a
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1305: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Benthic biogeographic patterns on the deep Brazilian margin.

Gaurisas, Daniela Y / Bernardino, Angelo F

PeerJ

2023 Volume 11, Page(s) e14585

Abstract: ... 200-5,000 m) using available faunal distributions. We retrieved over 4,000 benthic data records ... we propose the use of two biogeographic realms, two provinces and seven bathyal ecoregions (200-3,500 m), and ... three abyssal provinces (>3,500 m) along the BCM. The main driver for these units seems to be ...

Abstract	The Brazilian continental margin (BCM) extends from the Tropical to the Subtropical Atlantic Ocean, with much of its seafloor within deep waters, supporting rich geomorphological features and under wide productivity gradients. Deep-sea biogeographic boundaries on the BCM have been limited to studies that used water mass and salinity properties of deep-water masses, partly as a result of historical under sampling and a lack of consolidation of available biological and ecological datasets. The aim of this study was to consolidate benthic assemblage datasets and test current oceanographic biogeographical deep-sea boundaries (200-5,000 m) using available faunal distributions. We retrieved over 4,000 benthic data records from open-access databases and used cluster analysis to examine assemblage distributions against the deep-sea biogeographical classification scheme from Watling et al. (2013). Starting from the assumption that vertical and horizontal distribution patterns can vary regionally, we test other schemes incorporating latitudinal and water masses stratification within the Brazilian margin. As expected, the classification scheme based on benthic biodiversity is in overall agreement with the general boundaries proposed by Watling et al. (2013). However, our analysis allowed much refinement in the former boundaries, and here we propose the use of two biogeographic realms, two provinces and seven bathyal ecoregions (200-3,500 m), and three abyssal provinces (>3,500 m) along the BCM. The main driver for these units seems to be latitudinal gradients as well as water mass characteristics such as temperature. Our study provides a significant improvement of benthic biogeographic ranges along the Brazilian continental margin allowing a more detailed recognition of its biodiversity and ecological value, and also supports the needed spatial management for industrial activities occurring in its deep waters.
MeSH term(s)	Atlantic Ocean ; Biodiversity ; Brazil ; Water
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2023-02-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.14585
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Editorial comment to the paper: RE: low cubilin/myeloperoxidase's ratio as a promising biomarker for prognosis of high grade T1 bladder cancer.

Bernardino, Rui M / Wettstein, Marian / Garisto, Juan / Fleshner, Neil E

International urology and nephrology

2024

Language	English
Publishing date	2024-04-02
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	204048-7
ISSN	1573-2584 ; 0301-1623 ; 0042-1162
ISSN (online)	1573-2584
ISSN	0301-1623 ; 0042-1162
DOI	10.1007/s11255-024-04035-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 733: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Genome-scale prediction of bacterial promoters.

Bernardino, Miria / Beiko, Robert

Bio Systems

2022 Volume 221, Page(s) 104771

Abstract: A key step in the transcription of RNA is the binding of the RNA polymerase protein complex to a short promoter sequence that is typically upstream of the gene to be expressed. Automated identification of promoters would serve as a valuable complement to ...

Abstract	A key step in the transcription of RNA is the binding of the RNA polymerase protein complex to a short promoter sequence that is typically upstream of the gene to be expressed. Automated identification of promoters would serve as a valuable complement to experimental validation in determining which genes are likely to be expressed and when; however, promoter sequences are short and highly variable, which makes them very difficult to accurately classify. The many tools developed to identify promoters in DNA have generally been tested on small and balanced subsets of genomic sequence, and the results may not reflect their expected performance on genomes with millions of DNA base pairs where promoters are likely to comprise less than ∼1% of the sequence. Here we introduce Expositor, a neural-network-based method that uses different types of DNA encodings and tunable sensitivity and specificity parameters. Expositor showed higher sensitivity and precision on the E. coli K-12 MG1655 chromosome than other tested approaches. Expositor predictions were more consistent in the homologous subset of sequence from a strain of Salmonella than they were with another strain of E. coli. We also examined the accuracy of Expositor in distinguishing different classes of promoters and found that misclassification between classes was consistent with the biological similarity between promoters.
MeSH term(s)	DNA-Directed RNA Polymerases/genetics ; DNA-Directed RNA Polymerases/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Genome ; Genome, Bacterial/genetics ; Promoter Regions, Genetic/genetics ; RNA
Chemical Substances	RNA (63231-63-0) ; DNA-Directed RNA Polymerases (EC 2.7.7.6)
Language	English
Publishing date	2022-09-12
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	186234-0
ISSN	1872-8324 ; 0303-2647
ISSN (online)	1872-8324
ISSN	0303-2647
DOI	10.1016/j.biosystems.2022.104771
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 768: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Exploring the biotechnological potential of

Bernardino, Ana R S / Grosso, Filipa / Torres, Cristiana A V / Reis, Maria A M / Peixe, Luísa

Biotechnology reports (Amsterdam, Netherlands)

2024 Volume 42, Page(s) e00839

Abstract: A bacterium, ...

Abstract	A bacterium,
Language	English
Publishing date	2024-04-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2801018-8
ISSN	2215-017X
ISSN	2215-017X
DOI	10.1016/j.btre.2024.e00839
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Characterization of O/W emulgels based on whey protein-alginate-inulin coacervates: Influence of temperature and ultrasound as protein preconditioning process.

Ortiz-Deleón, Anthony M / Román-Guerrero, Angélica / Sandoval-Castilla, Ofelia / Cuevas-Bernardino, Juan Carlos

International journal of biological macromolecules

2024 Volume 265, Issue Pt 2, Page(s) 131260

Abstract: Preconditioning processes in proteins play a crucial role in enhancing their functional properties as surface active agents. Whey protein isolate (WPI, 20 wt%) was preconditioned via temperature ( ... ...

Abstract	Preconditioning processes in proteins play a crucial role in enhancing their functional properties as surface active agents. Whey protein isolate (WPI, 20 wt%) was preconditioned via temperature (WPI
MeSH term(s)	Whey Proteins/chemistry ; Temperature ; Inulin ; Emulsions/chemistry
Chemical Substances	Whey Proteins ; Inulin (9005-80-5) ; Emulsions
Language	English
Publishing date	2024-04-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.131260
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2374: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Wetness severity increases abrupt shifts in ecosystem functioning in arid savannas.

Vermeulen, L M / Verbist, B / Van Meerbeek, K / Slingsby, J / Bernardino, P N / Somers, B

Global change biology

2024 Volume 30, Issue 3, Page(s) e17235

Abstract: The accelerating pace of climate change has led to unprecedented shifts in surface temperature and precipitation patterns worldwide, with African savannas being among the most vulnerable regions. Understanding the impacts of these extreme changes on ... ...

Abstract	The accelerating pace of climate change has led to unprecedented shifts in surface temperature and precipitation patterns worldwide, with African savannas being among the most vulnerable regions. Understanding the impacts of these extreme changes on ecosystem health, functioning and stability is crucial. This paper focuses on the detection of breakpoints, indicative of shifts in ecosystem functioning, while also determining relevant ecosystem characteristics and climatic drivers that increase susceptibility to these shifts within the semi-arid to arid savanna biome. Utilising a remote sensing change detection approach and rain use efficiency (RaUE) as a proxy for ecosystem functioning, spatial and temporal patterns of breakpoints in the savanna biome were identified. We then employed a novel combination of survival analysis and remote sensing time series analysis to compare ecosystem characteristics and climatic drivers in areas experiencing breakpoints versus areas with stable ecosystem functioning. Key ecosystem factors increasing savanna breakpoint susceptibility were identified, namely higher soil sand content, flatter terrain and a cooler long-term mean temperature during the wet summer season. Moreover, the primary driver of changes in ecosystem functioning in arid savannas, as opposed to wetter tropical savannas, was found to be the increased frequency and severity of rainfall events, rather than drought pressures. This research highlights the importance of incorporating wetness severity metrics alongside drought metrics to comprehensively understand climate-ecosystem interactions leading to abrupt shifts in ecosystem functioning in arid biomes. The findings also emphasise the need to consider the underlying ecosystem characteristics, including soil, topography and vegetation composition, in assessing ecosystem responses to climate change. While this research primarily concentrated on the southern African savanna as a case study, the methodological robustness of this approach enables its application to diverse arid and semi-arid biomes for the assessment of climate-ecosystem interactions that contribute to abrupt shifts.
MeSH term(s)	Ecosystem ; Grassland ; Rain ; Seasons ; Soil
Chemical Substances	Soil
Language	English
Publishing date	2024-03-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1281439-8
ISSN	1365-2486 ; 1354-1013
ISSN (online)	1365-2486
ISSN	1354-1013
DOI	10.1111/gcb.17235
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 6338: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Interactions of mitochondrial and skeletal muscle biology in mitochondrial myopathy.

Di Leo, Valeria / Bernardino Gomes, Tiago M / Vincent, Amy E

The Biochemical journal

2023 Volume 480, Issue 21, Page(s) 1767–1789

Abstract: Mitochondrial dysfunction in skeletal muscle fibres occurs with both healthy aging and a range of neuromuscular diseases. The impact of mitochondrial dysfunction in skeletal muscle and the way muscle fibres adapt to this dysfunction is important to ... ...

Abstract	Mitochondrial dysfunction in skeletal muscle fibres occurs with both healthy aging and a range of neuromuscular diseases. The impact of mitochondrial dysfunction in skeletal muscle and the way muscle fibres adapt to this dysfunction is important to understand disease mechanisms and to develop therapeutic interventions. Furthermore, interactions between mitochondrial dysfunction and skeletal muscle biology, in mitochondrial myopathy, likely have important implications for normal muscle function and physiology. In this review, we will try to give an overview of what is known to date about these interactions including metabolic remodelling, mitochondrial morphology, mitochondrial turnover, cellular processes and muscle cell structure and function. Each of these topics is at a different stage of understanding, with some being well researched and understood, and others in their infancy. Furthermore, some of what we know comes from disease models. Whilst some findings are confirmed in humans, where this is not yet the case, we must be cautious in interpreting findings in the context of human muscle and disease. Here, our goal is to discuss what is known, highlight what is unknown and give a perspective on the future direction of research in this area.
MeSH term(s)	Humans ; Muscle, Skeletal/metabolism ; Mitochondrial Myopathies/genetics ; Mitochondrial Myopathies/metabolism ; Mitochondria/metabolism ; Mitochondrial Turnover ; Biology
Language	English
Publishing date	2023-11-15
Publishing country	England
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2969-5
ISSN	1470-8728 ; 0006-2936 ; 0306-3275 ; 0264-6021
ISSN (online)	1470-8728
ISSN	0006-2936 ; 0306-3275 ; 0264-6021
DOI	10.1042/BCJ20220233
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.110: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: MicroRNA-124-3p Modulates Alpha-Synuclein Expression Levels in a Paraquat-Induced in vivo Model for Parkinson's Disease.

Esteves, Marta / Cristóvão, Ana Clara / Vale, Ana / Machado-Pereira, Marta / Ferreira, Raquel / Bernardino, Liliana

Neurochemical research

2024

Abstract: Parkinson's disease (PD) is the second most prevalent neurodegenerative disease and the most common movement disorder. Although PD etiology is not fully understood, alpha (α)-synuclein is a key protein involved in PD pathology. MicroRNAs (miRNA), small ... ...

Abstract	Parkinson's disease (PD) is the second most prevalent neurodegenerative disease and the most common movement disorder. Although PD etiology is not fully understood, alpha (α)-synuclein is a key protein involved in PD pathology. MicroRNAs (miRNA), small gene regulatory RNAs that control gene expression, have been identified as biomarkers and potential therapeutic targets for brain diseases, including PD. In particular, miR-124 is downregulated in the plasma and brain samples of PD patients. Recently we showed that the brain delivery of miR-124 counteracts 6-hydroxydopamine-induced motor deficits. However, its role in α-synuclein pathology has never been addressed. Here we used paraquat (PQ)-induced rat PD model to evaluate the role of miR-124-3p in α-synuclein accumulation and dopaminergic neuroprotection. Our results showed that an intranigral administration of miR-124-3p reduced the expression and aggregation of α-synuclein in the substantia nigra (SN) of rats exposed to PQ. NADPH oxidases (NOX), responsible for reactive oxygen species generation, have been considered major players in the development of α-synuclein pathology. Accordingly, miR-124-3p decreased protein expression levels of NOX1 and its activator, small GTPase Rac1, in the SN of PQ-lesioned rats. Moreover, miR-124-3p was able to counteract the reduced levels of pituitary homeobox 3 (PITX3), a protein required for the dopaminergic phenotype, induced by PQ in the SN. This is the first study showing that miR-124-3p decreases PQ-induced α-synuclein levels and the associated NOX1/Rac1 signaling pathway, and impacts PITX3 protein levels, supporting the potential of miR-124-3p as a disease-modifying agent for PD and related α-synucleinopathies.
Language	English
Publishing date	2024-03-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	199335-5
ISSN	1573-6903 ; 0364-3190
ISSN (online)	1573-6903
ISSN	0364-3190
DOI	10.1007/s11064-024-04130-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1368: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito